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Volumn 16, Issue 8, 2005, Pages 3488-3500

Cathepsin B regulates the intrinsic angiogenic threshold of endothelial cells

Author keywords

[No Author keywords available]

Indexed keywords

CATHEPSIN B; COMPLEMENTARY DNA; ENDOSTATIN; HYPOXIA INDUCIBLE FACTOR 1ALPHA; LYSOSOME ENZYME; MESSENGER RNA; PROTEINASE; RETROVIRUS VECTOR; SMALL INTERFERING RNA; VASCULOTROPIN;

EID: 23044432584     PISSN: 10591524     EISSN: None     Source Type: Journal    
DOI: 10.1091/mbc.E04-11-1029     Document Type: Article
Times cited : (119)

References (58)
  • 1
    • 0026715161 scopus 로고
    • Peptidyl fluoromethyl ketones as inhibitors of cathepsin B. Implication for treatment of rheumatoid arthritis
    • Ahmed, N. K., Martin, L. A., Watts, L. M., Palmer, J., Thomburg, L., Prior, J., and Esser, R. E. (1992). Peptidyl fluoromethyl ketones as inhibitors of cathepsin B. Implication for treatment of rheumatoid arthritis. Biochem. Pharmacol. 44, 1201-1207.
    • (1992) Biochem. Pharmacol. , vol.44 , pp. 1201-1207
    • Ahmed, N.K.1    Martin, L.A.2    Watts, L.M.3    Palmer, J.4    Thomburg, L.5    Prior, J.6    Esser, R.E.7
  • 2
    • 0027942607 scopus 로고
    • Vascular endothelial growth factor in ocular fluid of patients with diabetic retinopathy and other retinal disorders
    • Aiello, L. P. et al. (1994). Vascular endothelial growth factor in ocular fluid of patients with diabetic retinopathy and other retinal disorders. N. Engl. J. Med. 331, 1519-1520.
    • (1994) N. Engl. J. Med. , vol.331 , pp. 1519-1520
    • Aiello, L.P.1
  • 3
    • 0017886726 scopus 로고
    • The specificity of cathepsin B. Hydrolysis of glucagon at the C-terminus by a peptidyldipeptidase mechanism
    • Aronson, N. N., Jr., and Barrett, A. J. (1978). The specificity of cathepsin B. Hydrolysis of glucagon at the C-terminus by a peptidyldipeptidase mechanism. Biochem. J. 171, 759-765.
    • (1978) Biochem. J. , vol.171 , pp. 759-765
    • Aronson Jr., N.N.1    Barrett, A.J.2
  • 4
    • 0037136311 scopus 로고    scopus 로고
    • Surface cathepsin B protects cytotoxic lymphocytes from self-destruction after degranulation
    • Balaji, K. N., Schaschke, N., Machleidt, W., Catalfamo, M., and Henkart, P. A. (2002). Surface cathepsin B protects cytotoxic lymphocytes from self-destruction after degranulation. J. Exp. Med. 196, 493-503.
    • (2002) J. Exp. Med. , vol.196 , pp. 493-503
    • Balaji, K.N.1    Schaschke, N.2    Machleidt, W.3    Catalfamo, M.4    Henkart, P.A.5
  • 5
    • 0019765848 scopus 로고
    • Cathepsin B, Cathepsin H, and cathepsin L
    • Barrett, A. J., and Kirschke, H. (1981). Cathepsin B, Cathepsin H, and cathepsin L. Methods Enzymol. 80 (Pt C), 535-561.
    • (1981) Methods Enzymol. , vol.80 , Issue.PART C , pp. 535-561
    • Barrett, A.J.1    Kirschke, H.2
  • 6
    • 0000391746 scopus 로고    scopus 로고
    • Matrix metalloproteinase-9 triggers the angiogenic switch during carcinogenesis
    • Bergers, G. et al. (2000). Matrix metalloproteinase-9 triggers the angiogenic switch during carcinogenesis. Nat. Cell Biol. 2, 737-744.
    • (2000) Nat. Cell Biol. , vol.2 , pp. 737-744
    • Bergers, G.1
  • 7
    • 0026575258 scopus 로고
    • Degradation of extracellular-matrix proteins by human cathepsin B from normal and tumour tissues
    • Buck, M. R., Karustis, D. G., Day, N. A., Honn, K. V., and Sloane, B. F. (1992). Degradation of extracellular-matrix proteins by human cathepsin B from normal and tumour tissues. Biochem. J. 282, 273-278.
    • (1992) Biochem. J. , vol.282 , pp. 273-278
    • Buck, M.R.1    Karustis, D.G.2    Day, N.A.3    Honn, K.V.4    Sloane, B.F.5
  • 8
    • 0344844410 scopus 로고    scopus 로고
    • Activation of vascular endothelial growth factor receptor-1 sustains angiogenesis and Bcl-2 expression via the phosphatidylinositol 3-kinase pathway in endothelial cells
    • Cai, J., Ahmad, S., Jiang, W. G., Huang, J., Kontos, C. D., Boulton, M., and Ahmed, A. (2003). Activation of vascular endothelial growth factor receptor-1 sustains angiogenesis and Bcl-2 expression via the phosphatidylinositol 3-kinase pathway in endothelial cells. Diabetes 52, 2959-2968.
    • (2003) Diabetes , vol.52 , pp. 2959-2968
    • Cai, J.1    Ahmad, S.2    Jiang, W.G.3    Huang, J.4    Kontos, C.D.5    Boulton, M.6    Ahmed, A.7
  • 9
    • 0034648765 scopus 로고    scopus 로고
    • Angiogenesis in cancer and other diseases
    • Carmeliet, P., and Jain, R. K. (2000). Angiogenesis in cancer and other diseases. Nature 407, 249-257.
    • (2000) Nature , vol.407 , pp. 249-257
    • Carmeliet, P.1    Jain, R.K.2
  • 10
    • 0030833817 scopus 로고    scopus 로고
    • CD36 mediates the in vitro inhibitory effects of thrombospondin-1 on endothelial cells
    • Dawson, D. W., Pearce, S. F., Zhong, R., Silverstein, R. L., Frazier, W. A., and Bouck, N. P. (1997). CD36 mediates the in vitro inhibitory effects of thrombospondin-1 on endothelial cells. J. Cell Biol. 138, 707-717.
    • (1997) J. Cell Biol. , vol.138 , pp. 707-717
    • Dawson, D.W.1    Pearce, S.F.2    Zhong, R.3    Silverstein, R.L.4    Frazier, W.A.5    Bouck, N.P.6
  • 11
    • 0037025342 scopus 로고    scopus 로고
    • Cathepsin L. and cathepsin B mediate reovirus disassembly in murine fibroblast cells
    • Ebert, D. H., Deussing, J., Peters, C., and Dermody, T. S. (2002). Cathepsin L. and cathepsin B mediate reovirus disassembly in murine fibroblast cells. J. Biol. Chem. 277, 24609-24617.
    • (2002) J. Biol. Chem. , vol.277 , pp. 24609-24617
    • Ebert, D.H.1    Deussing, J.2    Peters, C.3    Dermody, T.S.4
  • 12
    • 0027296221 scopus 로고
    • The effects of fluoromethyl ketone inhibitors of cathepsin B on adjuvant induced arthritis
    • Esser, R. E., Watts, L. M., Angelo, R. A., Thornburg, L. P., Prior, J. J., and Palmer, J. T. (1993). The effects of fluoromethyl ketone inhibitors of cathepsin B on adjuvant induced arthritis. J. Rheumatol. 20, 1176-1183.
    • (1993) J. Rheumatol. , vol.20 , pp. 1176-1183
    • Esser, R.E.1    Watts, L.M.2    Angelo, R.A.3    Thornburg, L.P.4    Prior, J.J.5    Palmer, J.T.6
  • 13
  • 15
    • 0031039243 scopus 로고    scopus 로고
    • The biology of vascular endothelial growth factor
    • Ferrara, N., and Davis-Smyth, T. (1997). The biology of vascular endothelial growth factor. Endocr. Rev. 18, 4-25.
    • (1997) Endocr. Rev. , vol.18 , pp. 4-25
    • Ferrara, N.1    Davis-Smyth, T.2
  • 16
    • 0037699954 scopus 로고    scopus 로고
    • The biology of VEGF and its receptors
    • Ferrara, N., Gerber, H. P., and LeCouter, J. (2003). The biology of VEGF and its receptors. Nat. Med. 9, 669-676.
    • (2003) Nat. Med. , vol.9 , pp. 669-676
    • Ferrara, N.1    Gerber, H.P.2    Lecouter, J.3
  • 17
    • 0034672644 scopus 로고    scopus 로고
    • Generation and degradation of human endostarin proteins by various proteinases
    • Ferreras, M., Felbor, U., Lenhard, T., Olsen, B. R., and Delaisse, J. (2000). Generation and degradation of human endostarin proteins by various proteinases. FEBS Lett. 486, 247-251.
    • (2000) FEBS Lett. , vol.486 , pp. 247-251
    • Ferreras, M.1    Felbor, U.2    Lenhard, T.3    Olsen, B.R.4    Delaisse, J.5
  • 18
    • 0028929803 scopus 로고
    • Angiogenesis in cancer, vascular, rheumatoid and other disease
    • Folkman, J. (1995). Angiogenesis in cancer, vascular, rheumatoid and other disease. Nat. Med. 1, 27-31.
    • (1995) Nat. Med. , vol.1 , pp. 27-31
    • Folkman, J.1
  • 19
    • 0029761644 scopus 로고    scopus 로고
    • Activation of vascular endothelial growth factor gene transcription by hypoxia-inducible factor 1
    • Forsythe, J. A., Jiang, B. H., Iyer, N. V., Agani, F., Leung, S. W., Koos, R. D., and Semenza, G. L., (1996). Activation of vascular endothelial growth factor gene transcription by hypoxia-inducible factor 1. Mol. Cell Biol. 16, 4604-4613.
    • (1996) Mol. Cell Biol. , vol.16 , pp. 4604-4613
    • Forsythe, J.A.1    Jiang, B.H.2    Iyer, N.V.3    Agani, F.4    Leung, S.W.5    Koos, R.D.6    Semenza, G.L.7
  • 20
    • 18444389460 scopus 로고    scopus 로고
    • Lack of collagen XVIII/endostatin results in eye abnormalities
    • Fukai, N. et al. (2002). Lack of collagen XVIII/endostatin results in eye abnormalities. EMBO J. 21, 1535-1544.
    • (2002) EMBO J. , vol.21 , pp. 1535-1544
    • Fukai, N.1
  • 21
    • 0020571614 scopus 로고
    • Culture of retinal capillary cells using selective growth media
    • Gitlin, J. D., and D'Amore, P. A. (1983). Culture of retinal capillary cells using selective growth media. Microvasc. Res. 26, 74-80.
    • (1983) Microvasc. Res. , vol.26 , pp. 74-80
    • Gitlin, J.D.1    D'Amore, P.A.2
  • 22
    • 0025147371 scopus 로고
    • A tumor suppressor-dependent inhibitor of angiogenesis is immunologically and functionally indistinguishable from a fragment of thrombospondin
    • Good, D. J., Polverini, P. J., Rastinejad, F., Le Beau, M. M., Lemons, R. S., Frazier, W. A., and Bouck, N. P. (1990). A tumor suppressor-dependent inhibitor of angiogenesis is immunologically and functionally indistinguishable from a fragment of thrombospondin. Proc. Natl. Acad. Sci. USA 87, 6624-6628.
    • (1990) Proc. Natl. Acad. Sci. USA , vol.87 , pp. 6624-6628
    • Good, D.J.1    Polverini, P.J.2    Rastinejad, F.3    Le Beau, M.M.4    Lemons, R.S.5    Frazier, W.A.6    Bouck, N.P.7
  • 23
    • 0033756474 scopus 로고    scopus 로고
    • Cathepsin B contributes to TNF-alpha-mediated hepatocyte apoptosis by promoting mitochondrial release of cytochrome c
    • Guicciardi, M. E., Deussing, J., Miyoshi, H., Bronk, S. F., Svingen, P. A., Peters, C., Kaufmann, S. H., and Gores, G. (2000). Cathepsin B contributes to TNF-alpha-mediated hepatocyte apoptosis by promoting mitochondrial release of cytochrome c. J. Clin. Invest. 106, 1127-1137.
    • (2000) J. Clin. Invest. , vol.106 , pp. 1127-1137
    • Guicciardi, M.E.1    Deussing, J.2    Miyoshi, H.3    Bronk, S.F.4    Svingen, P.A.5    Peters, C.6    Kaufmann, S.H.7    Gores, G.8
  • 25
    • 0030576517 scopus 로고    scopus 로고
    • Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis
    • Hanahan, D., and Folkman, J. (1996). Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis. Cell 86, 353-364.
    • (1996) Cell , vol.86 , pp. 353-364
    • Hanahan, D.1    Folkman, J.2
  • 26
    • 0037119415 scopus 로고    scopus 로고
    • Hsp90 regulates a von Hippel Lindau-independent hypoxia-inducible factor-1 alpha-degradative pathway
    • Isaacs, J. S., Jung, Y. J., Mimnaugh, E. G., Martinez, A., Cuttitta, F., and Neckers, L. M. (2002). Hsp90 regulates a von Hippel Lindau-independent hypoxia-inducible factor-1 alpha-degradative pathway. J. Biol. Chem. 277, 29936-29944.
    • (2002) J. Biol. Chem. , vol.277 , pp. 29936-29944
    • Isaacs, J.S.1    Jung, Y.J.2    Mimnaugh, E.G.3    Martinez, A.4    Cuttitta, F.5    Neckers, L.M.6
  • 27
    • 0035917808 scopus 로고    scopus 로고
    • Targeting of HIF-alpha to the von Hippel-Lindau ubiquitylation complex by deregulated prolyl hydroxylation
    • Jaakkola, P. et al. (2001). Targeting of HIF-alpha to the von Hippel-Lindau ubiquitylation complex by deregulated prolyl hydroxylation. Science 292, 468-472.
    • (2001) Science , vol.292 , pp. 468-472
    • Jaakkola, P.1
  • 30
    • 0032764742 scopus 로고    scopus 로고
    • A model system for the study of human retinal angiogenesis: Activation of monocytes and endothelial cells and the association with the expression of the monocarboxylate transporter type 1 (MCT-1)
    • Knott, R. M., Robertson, M., Muckersie, E., Folefac, V. A., Fairhurst, F. E., Wileman, S. M., and Forrester, J. V. (1999). A model system for the study of human retinal angiogenesis: activation of monocytes and endothelial cells and the association with the expression of the monocarboxylate transporter type 1 (MCT-1). Diabetologia 42, 870-877.
    • (1999) Diabetologia , vol.42 , pp. 870-877
    • Knott, R.M.1    Robertson, M.2    Muckersie, E.3    Folefac, V.A.4    Fairhurst, F.E.5    Wileman, S.M.6    Forrester, J.V.7
  • 31
    • 0025845425 scopus 로고
    • Cathepsin B efficiently activates the soluble and the tumor cell receptor-bound form of the proenzyme urokinase-type plasminogen activator (Pro-uPA)
    • Kobayashi, H., Schmitt, M., Goretzki, L., Chucholowski, N., Calvete, J., Kramer, M., Gunzler, W. A., Janicke, F., and Graeff, H. (1991). Cathepsin B efficiently activates the soluble and the tumor cell receptor-bound form of the proenzyme urokinase-type plasminogen activator (Pro-uPA). J. Biol. Chem. 266, 5147-5152.
    • (1991) J. Biol. Chem. , vol.266 , pp. 5147-5152
    • Kobayashi, H.1    Schmitt, M.2    Goretzki, L.3    Chucholowski, N.4    Calvete, J.5    Kramer, M.6    Gunzler, W.A.7    Janicke, F.8    Graeff, H.9
  • 33
    • 0035911957 scopus 로고    scopus 로고
    • Oligomerization-dependent regulation of motility and morphogenesis by the collagen XVIII NC1/endostatin domain
    • Kuo, C. J. et al. (2001). Oligomerization-dependent regulation of motility and morphogenesis by the collagen XVIII NC1/endostatin domain. J. Cell Biol. 152, 1233-1246.
    • (2001) J. Cell Biol. , vol.152 , pp. 1233-1246
    • Kuo, C.J.1
  • 34
    • 0033567263 scopus 로고    scopus 로고
    • Exocytosis of active cathepsin B enzyme activity at pH 7.0, inhibition and molecular mass
    • Linebaugh, B. E., Sameni, M., Day, N. A., Sloane, B. F., and Keppler, D. (1999). Exocytosis of active cathepsin B enzyme activity at pH 7.0, inhibition and molecular mass. Eur. J. Biochem. 264, 100-109.
    • (1999) Eur. J. Biochem. , vol.264 , pp. 100-109
    • Linebaugh, B.E.1    Sameni, M.2    Day, N.A.3    Sloane, B.F.4    Keppler, D.5
  • 35
    • 8044250876 scopus 로고    scopus 로고
    • A possible role for cathepsins D, E, and B in the processing of beta-amyloid precursor protein in Alzheimer's disease
    • Mackay, E. A. et al. (1997). A possible role for cathepsins D, E, and B in the processing of beta-amyloid precursor protein in Alzheimer's disease. Eur. J. Biochem. 244, 414-425.
    • (1997) Eur. J. Biochem. , vol.244 , pp. 414-425
    • Mackay, E.A.1
  • 36
    • 0036754586 scopus 로고    scopus 로고
    • Degradation of extracellular matrix protein tenascin-C by cathepsin B: An interaction involved in the progression of gliomas
    • Mai, J., Sameni, M., Mikkelsen, T., and Sloane, B. F. (2002). Degradation of extracellular matrix protein tenascin-C by cathepsin B: an interaction involved in the progression of gliomas. Biol. Chem. 383, 1407-1413.
    • (2002) Biol. Chem. , vol.383 , pp. 1407-1413
    • Mai, J.1    Sameni, M.2    Mikkelsen, T.3    Sloane, B.F.4
  • 37
    • 3843095197 scopus 로고    scopus 로고
    • HIF-1's relationship to oxygen: Simple yet sophisticated
    • Maxwell, P. H. (2004). HIF-1's relationship to oxygen: simple yet sophisticated. Cell Cycle 3, 156-159.
    • (2004) Cell Cycle , vol.3 , pp. 156-159
    • Maxwell, P.H.1
  • 39
    • 0027970092 scopus 로고
    • Angiostatin: A novel angiogenesis inhibitor that mediates the suppression of metastases by a Lewis lung carcinoma
    • O'Reilly, M. S., Holmgren, L., Shing, Y., Chen, C., Rosenthal, R. A., Moses, M., Lane, W. S., Cao, Y., Sage, E. H., and Folkman, J. (1994). Angiostatin: a novel angiogenesis inhibitor that mediates the suppression of metastases by a Lewis lung carcinoma. Cell 79, 315-328.
    • (1994) Cell , vol.79 , pp. 315-328
    • O'Reilly, M.S.1    Holmgren, L.2    Shing, Y.3    Chen, C.4    Rosenthal, R.A.5    Moses, M.6    Lane, W.S.7    Cao, Y.8    Sage, E.H.9    Folkman, J.10
  • 40
    • 0344637004 scopus 로고    scopus 로고
    • Systemic activation of the vascular endothelial growth factor receptor KDR/flk-1 selectively triggers endothelial cells with an angiogenic phenotype
    • Ortega, N., Jonca, F., Vincent, S., Favard, C., Ruchoux, M. M., and Plouet, J. (1997). Systemic activation of the vascular endothelial growth factor receptor KDR/flk-1 selectively triggers endothelial cells with an angiogenic phenotype. Am. J. Pathol. 151, 1215-1224.
    • (1997) Am. J. Pathol. , vol.151 , pp. 1215-1224
    • Ortega, N.1    Jonca, F.2    Vincent, S.3    Favard, C.4    Ruchoux, M.M.5    Plouet, J.6
  • 41
    • 0029862497 scopus 로고    scopus 로고
    • A stable human-derived packaging cell line for production of high titer retrovirus/vesicular stomatitis virus G pseudotypes
    • Ory, D. S., Neugeboren, B. A., and Mulligan, R. C. (1996). A stable human-derived packaging cell line for production of high titer retrovirus/vesicular stomatitis virus G pseudotypes. Proc. Natl. Acad. Sci. USA 93, 11400-11406.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 11400-11406
    • Ory, D.S.1    Neugeboren, B.A.2    Mulligan, R.C.3
  • 42
    • 3042701598 scopus 로고    scopus 로고
    • Hypoxia activates matrix metalloproteinase expression and the VEGF system in monkey choroid-retinal endothelial cells: Involvement of cytosolic phospholipase A2 activity
    • Ottino, P., Finley, J., Rojo, E., Ottlecz, A., Lambrou, G. N., Bazan, H. E., and Bazan, N. G. (2004). Hypoxia activates matrix metalloproteinase expression and the VEGF system in monkey choroid-retinal endothelial cells: Involvement of cytosolic phospholipase A2 activity. Mol. Vis. 10, 341-350.
    • (2004) Mol. Vis. , vol.10 , pp. 341-350
    • Ottino, P.1    Finley, J.2    Rojo, E.3    Ottlecz, A.4    Lambrou, G.N.5    Bazan, H.E.6    Bazan, N.G.7
  • 43
    • 0026446102 scopus 로고
    • Vascular endothelial growth factor is a potential tumour angiogenesis factor in human gliomas in vivo
    • Plate, K. H., Breier, G., Weich, H. A., and Risau, W. (1992). Vascular endothelial growth factor is a potential tumour angiogenesis factor in human gliomas in vivo. Nature 359, 845-848.
    • (1992) Nature , vol.359 , pp. 845-848
    • Plate, K.H.1    Breier, G.2    Weich, H.A.3    Risau, W.4
  • 44
    • 0024322516 scopus 로고
    • Expression of five cathepsins in murine melanomas of varying metastatic potential and normal tissues
    • Qian, F., Bajkowski, A. S., Steiner, D. F., Chan, S. J., and Frankfater, A. (1989). Expression of five cathepsins in murine melanomas of varying metastatic potential and normal tissues. Cancer Res. 49, 4870-4875.
    • (1989) Cancer Res. , vol.49 , pp. 4870-4875
    • Qian, F.1    Bajkowski, A.S.2    Steiner, D.F.3    Chan, S.J.4    Frankfater, A.5
  • 45
    • 0022398321 scopus 로고
    • Synthesis of peptide fluoromethyl ketones and the inhibition of human cathepsin B
    • Rasnick, D. (1985). Synthesis of peptide fluoromethyl ketones and the inhibition of human cathepsin B. Anal Biochem. 149, 461-465.
    • (1985) Anal Biochem. , vol.149 , pp. 461-465
    • Rasnick, D.1
  • 46
    • 0035862167 scopus 로고    scopus 로고
    • Nuclear localization of cystatin B, the cathepsin inhibitor implicated in myoclonus epilepsy (EPM1)
    • Riccio, M., Di Giaimo, R., Pianetti, S., Palmieri, P. P., Melli, M., and Santi, S. (2001). Nuclear localization of cystatin B, the cathepsin inhibitor implicated in myoclonus epilepsy (EPM1). Exp. Cell Res. 262, 84-94.
    • (2001) Exp. Cell Res. , vol.262 , pp. 84-94
    • Riccio, M.1    Di Giaimo, R.2    Pianetti, S.3    Palmieri, P.P.4    Melli, M.5    Santi, S.6
  • 47
    • 0035940429 scopus 로고    scopus 로고
    • Thrombospondin-1 suppresses spontaneous tumor growth and inhibits activation of matrix metalloproteiriase-9 and mobilization of vascular endothelial growth factor
    • Rodriguez-Manzaneque, J. C., Lane, T. F., Ortega, M. A., Hynes, R. O., Lawler, J., and Iruela-Arispe, M. L. (2001). Thrombospondin-1 suppresses spontaneous tumor growth and inhibits activation of matrix metalloproteiriase-9 and mobilization of vascular endothelial growth factor. Proc. Natl. Acad. Sci. USA 38, 12485-12490.
    • (2001) Proc. Natl. Acad. Sci. USA , vol.38 , pp. 12485-12490
    • Rodriguez-Manzaneque, J.C.1    Lane, T.F.2    Ortega, M.A.3    Hynes, R.O.4    Lawler, J.5    Iruela-Arispe, M.L.6
  • 48
    • 0035877804 scopus 로고    scopus 로고
    • The cathepsin B inhibitor z-FA.fmk inhibits cytokine production in macrophages stimulated by lipopolysaccharide
    • Schotte, P., Schauvliege, R., Janssens, S., and Beyaert, R. (2001). The cathepsin B inhibitor z-FA.fmk inhibits cytokine production in macrophages stimulated by lipopolysaccharide. J. Biol. Chem. 276, 21153-21157.
    • (2001) J. Biol. Chem. , vol.276 , pp. 21153-21157
    • Schotte, P.1    Schauvliege, R.2    Janssens, S.3    Beyaert, R.4
  • 49
    • 0032500886 scopus 로고    scopus 로고
    • Cathepsin B-mediated activation of the proinflammatory caspase-11
    • Schotte, P. et al. (1998). Cathepsin B-mediated activation of the proinflammatory caspase-11. Biochem. Biophys. Res. Commun. 252, 379-387.
    • (1998) Biochem. Biophys. Res. Commun. , vol.252 , pp. 379-387
    • Schotte, P.1
  • 50
    • 0034663989 scopus 로고    scopus 로고
    • HIF-1 and human disease: One highly involved factor
    • Semenza, G. L. (2000). HIF-1 and human disease: one highly involved factor. Genes Dev. 24, 1983-1991.
    • (2000) Genes Dev. , vol.24 , pp. 1983-1991
    • Semenza, G.L.1
  • 53
    • 0034615570 scopus 로고    scopus 로고
    • Lysosomal cysteine proteases: More than scavengers
    • Turk, B., Turk, D., and Turk, V. (2000). Lysosomal cysteine proteases: more than scavengers. Biochim. Biophys. Acta 1477, 98-111.
    • (2000) Biochim. Biophys. Acta , vol.1477 , pp. 98-111
    • Turk, B.1    Turk, D.2    Turk, V.3
  • 54
    • 0027506762 scopus 로고
    • Tyrosines 1021 and 1009 are phosphorylation sites in the carboxy terminus of the platelet-derived growth factor receptor beta subunit and are required for binding of phospholipase C gamma and a 64-kilodalton protein, respectively
    • Valius, M., Bazenet, C., and Kazlauskas, A. (1993). Tyrosines 1021 and 1009 are phosphorylation sites in the carboxy terminus of the platelet-derived growth factor receptor beta subunit and are required for binding of phospholipase C gamma and a 64-kilodalton protein, respectively. Mol. Cell Biol. 13, 133-143.
    • (1993) Mol. Cell Biol. , vol.13 , pp. 133-143
    • Valius, M.1    Bazenet, C.2    Kazlauskas, A.3
  • 55
    • 0042972556 scopus 로고    scopus 로고
    • Ras modulates Myc activity to repress thrombospondin-1 expression and increase tumor angiogenesis
    • Watnick, R. S., Cheng, Y. N., Rangarajan, A., Ince, T. A., and Weinberg, R. A. (2003). Ras modulates Myc activity to repress thrombospondin-1 expression and increase tumor angiogenesis. Cancer Cell 3, 219-231.
    • (2003) Cancer Cell , vol.3 , pp. 219-231
    • Watnick, R.S.1    Cheng, Y.N.2    Rangarajan, A.3    Ince, T.A.4    Weinberg, R.A.5
  • 57
    • 0012330613 scopus 로고    scopus 로고
    • Importance of lysosomal cysteine proteases in lung disease
    • Wolters, P. J., and Chapman, H. A. (2000). Importance of lysosomal cysteine proteases in lung disease. Respir. Res. 1, 170-177.
    • (2000) Respir. Res. , vol.1 , pp. 170-177
    • Wolters, P.J.1    Chapman, H.A.2
  • 58
    • 1842538729 scopus 로고    scopus 로고
    • Blockade of cathepsin B expression in human glioblastoma cells is associated with suppression of angiogenesis
    • Yanamandra, N., Gumidyala, K. V., Waldron, K. G., Gujrati, M., Olivero, W. C., Dinh, D. H., Rao, J. S., and Mohanam, S. (2004). Blockade of cathepsin B expression in human glioblastoma cells is associated with suppression of angiogenesis. Oncogene 23, 2224-2230.
    • (2004) Oncogene , vol.23 , pp. 2224-2230
    • Yanamandra, N.1    Gumidyala, K.V.2    Waldron, K.G.3    Gujrati, M.4    Olivero, W.C.5    Dinh, D.H.6    Rao, J.S.7    Mohanam, S.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.