Induction of G1 and G2/M cell cycle arrests by the dietary compound 3,3′-diindolylmethane in HT-29 human colon cancer cells

BMC Gastroenterology

Volumn 9, Issue , 2009, Pages

  Choi, Hyun Ju ^a   Lim, Do Young ^a   Park, Jung Han Yoon ^a  

^a Hallym University   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

3,3' DIINDOLYLMETHANE; BETA ACTIN; CELL DEPENDENT KINASE 25C PHOSPHATASE; CYCLIN A; CYCLIN B1; CYCLIN D1; CYCLIN DEPENDENT KINASE 1; CYCLIN DEPENDENT KINASE 4; CYCLIN DEPENDENT KINASE INHIBITOR 1; CYCLIN DEPENDENT KINASE INHIBITOR 1B; CYCLIN E; PHOSPHOTRANSFERASE; PROPIDIUM IODIDE; PROTEIN P16; PROTEIN TYROSINE PHOSPHATASE; RETINOBLASTOMA PROTEIN; THYMIDINE; TRANSCRIPTION FACTOR E2F1; UNCLASSIFIED DRUG; 3,3'-DIINDOLYLMETHANE; ANTINEOPLASTIC AGENT; CDC2 PROTEIN, HUMAN; CDK2 PROTEIN, HUMAN; CDK4 PROTEIN, HUMAN; CDKN1A PROTEIN, HUMAN; CYCLIN B; CYCLIN DEPENDENT KINASE 2; CYCLIN DEPENDENT KINASE INHIBITOR 1A; DNA; INDOLE DERIVATIVE;

ARTICLE; CELL CYCLE ARREST; CELL CYCLE G1 PHASE; CELL CYCLE G2 PHASE; CELL CYCLE PROGRESSION; CELL CYCLE S PHASE; CELL STRAIN HT29; COLON CANCER; CONCENTRATION RESPONSE; CONTROLLED STUDY; DNA SYNTHESIS; DRUG MECHANISM; ENZYME ACTIVITY; FLOW CYTOMETRY; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; IN VITRO STUDY; PROTEIN PHOSPHORYLATION; WESTERN BLOTTING; ADENOCARCINOMA; CELL CYCLE; CELL DIVISION; COLON TUMOR; DOSE RESPONSE; DRUG EFFECT; METABOLISM; PATHOLOGY; TUMOR CELL LINE;

ADENOCARCINOMA; ANTICARCINOGENIC AGENTS; CELL CYCLE; CELL DIVISION; CELL LINE, TUMOR; COLONIC NEOPLASMS; CYCLIN A; CYCLIN B; CYCLIN D1; CYCLIN-DEPENDENT KINASE 2; CYCLIN-DEPENDENT KINASE 4; CYCLIN-DEPENDENT KINASE INHIBITOR P21; CYCLIN-DEPENDENT KINASE INHIBITOR P27; DNA, NEOPLASM; DOSE-RESPONSE RELATIONSHIP, DRUG; G1 PHASE; G2 PHASE; HT29 CELLS; HUMANS; INDOLES;

EID: 67649641442     PISSN: None     EISSN: 1471230X     Source Type: Journal    
DOI: 10.1186/1471-230X-9-39     Document Type: Article

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