메뉴 건너뛰기




Volumn 15, Issue 12, 2006, Pages 2477-2481

Single-dose and multiple-dose administration of indole-3-carbinol to women: Pharmacokinetics based on 3,3′-diindolylmethane

Author keywords

[No Author keywords available]

Indexed keywords

3 INDOLEMETHANOL; 3,3' DIINDOLYLMETHANE; DRUG METABOLITE; UNCLASSIFIED DRUG;

EID: 33846024022     PISSN: 10559965     EISSN: None     Source Type: Journal    
DOI: 10.1158/1055-9965.EPI-06-0396     Document Type: Article
Times cited : (140)

References (31)
  • 1
    • 0018137952 scopus 로고
    • Inhibition of polycyclic aromatic hydrocarbon-induced neoplasia by naturally occurring indoles
    • Wattenberg LW, Loub WD. Inhibition of polycyclic aromatic hydrocarbon-induced neoplasia by naturally occurring indoles. Cancer Res 1978;38:1410-3.
    • (1978) Cancer Res , vol.38 , pp. 1410-1413
    • Wattenberg, L.W.1    Loub, W.D.2
  • 3
    • 0023760357 scopus 로고
    • 6- ethylguanine formation in rainbow trout by indole-3-carbinol, α-naphthoflavone, and Aroclor 1254
    • 6- ethylguanine formation in rainbow trout by indole-3-carbinol, α-naphthoflavone, and Aroclor 1254. Toxicol Appl Pharmacol 1988;96:93-100.
    • (1988) Toxicol Appl Pharmacol , vol.96 , pp. 93-100
    • Fong, A.T.1    Hendricks, J.D.2    Dashwood, R.H.3
  • 4
    • 0025776365 scopus 로고
    • Effects of dietary indole-3-carbinol on estradiol metabolism and spontaneous mammary tumors in mice
    • Bradlow HL, Michnovicz J, Telang NT, Osborne MP. Effects of dietary indole-3-carbinol on estradiol metabolism and spontaneous mammary tumors in mice. Carcinogenesis 1991;12:1571-4.
    • (1991) Carcinogenesis , vol.12 , pp. 1571-1574
    • Bradlow, H.L.1    Michnovicz, J.2    Telang, N.T.3    Osborne, M.P.4
  • 5
    • 0027254619 scopus 로고
    • Inhibition of tobacco-specific nitrosamine-induced lung tumorigenesis by compounds derived from cruciferous vegetables and green tea
    • Chung FL, Morse MA, Eklind KI, Xu Y. Inhibition of tobacco-specific nitrosamine-induced lung tumorigenesis by compounds derived from cruciferous vegetables and green tea. Ann N Y Acad Sci 1993;686:186-201.
    • (1993) Ann N Y Acad Sci , vol.686 , pp. 186-201
    • Chung, F.L.1    Morse, M.A.2    Eklind, K.I.3    Xu, Y.4
  • 6
    • 0028281779 scopus 로고
    • Chemoprevention of spontaneous endometrial cancer in female donryu rats by dietary indole-3-carbinol
    • Kojima T, Tanaka T, Mori H. Chemoprevention of spontaneous endometrial cancer in female donryu rats by dietary indole-3-carbinol. Cancer Res 1994;54:1446-9.
    • (1994) Cancer Res , vol.54 , pp. 1446-1449
    • Kojima, T.1    Tanaka, T.2    Mori, H.3
  • 7
    • 0029023920 scopus 로고
    • Chemoprevention of chemically-induced mammary carcinogenesis by indole-3-carbinol
    • Grubbs CJ, Steele VE, Casebolt T, et al. Chemoprevention of chemically-induced mammary carcinogenesis by indole-3-carbinol. Anticancer Res 1995;15:709-16.
    • (1995) Anticancer Res , vol.15 , pp. 709-716
    • Grubbs, C.J.1    Steele, V.E.2    Casebolt, T.3
  • 8
    • 0029909080 scopus 로고    scopus 로고
    • Effects of 1,4-phenylenebis (methylene)selenocyanate, phenethyl isothiocyanate, indole-3-carbinol, and d-limonene individually and in combination on the tumorigenicity of the tobacco-specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in A/J mouse lung
    • El Bayoumy K, Upadhyaya P, Desai DH, et al. Effects of 1,4-phenylenebis (methylene)selenocyanate, phenethyl isothiocyanate, indole-3-carbinol, and d-limonene individually and in combination on the tumorigenicity of the tobacco-specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in A/J mouse lung. Anticancer Res 1996;16:2709-12.
    • (1996) Anticancer Res , vol.16 , pp. 2709-2712
    • El Bayoumy, K.1    Upadhyaya, P.2    Desai, D.H.3
  • 9
    • 0033567096 scopus 로고    scopus 로고
    • Indole-3-carbinol prevents cervical cancer in human papilloma virus type 16 (HPV16) transgenic mice
    • Jin L, Qi M, Chen D-Z, et al. Indole-3-carbinol prevents cervical cancer in human papilloma virus type 16 (HPV16) transgenic mice. Cancer Res 1999;59:3991-7.
    • (1999) Cancer Res , vol.59 , pp. 3991-3997
    • Jin, L.1    Qi, M.2    Chen, D.-Z.3
  • 10
    • 0032782686 scopus 로고    scopus 로고
    • Chemoprevention of 2-amino-1-methyl-6-phenylimidazo[4,5]pyridine-induced mammary carcinogenesis in rats
    • Mori H, Sugie S, Rahman W, Suzui N. Chemoprevention of 2-amino-1-methyl-6-phenylimidazo[4,5]pyridine-induced mammary carcinogenesis in rats. Cancer Lett 1999;143:195-8.
    • (1999) Cancer Lett , vol.143 , pp. 195-198
    • Mori, H.1    Sugie, S.2    Rahman, W.3    Suzui, N.4
  • 11
    • 0031426564 scopus 로고    scopus 로고
    • Enhancement by indole-3-carbinol of liver and thyroid gland neoplastic development in a rat medium-term multiorgan carcinogenesis model
    • Kim DJ, Han BS, Ann B, et al. Enhancement by indole-3-carbinol of liver and thyroid gland neoplastic development in a rat medium-term multiorgan carcinogenesis model. Carcinogenesis 1997;18:377-81.
    • (1997) Carcinogenesis , vol.18 , pp. 377-381
    • Kim, D.J.1    Han, B.S.2    Ann, B.3
  • 12
    • 0035109432 scopus 로고    scopus 로고
    • Post-initiation effects of chlorophyllin and indole-3-carbinol in rats given 1,2-dimethylhydrazine or 2-amino-3-methylimidazo[4,5-f]quinoline
    • Xu M, Orner GA, Bailey GS, Stoner GD, Horio DT, Dashwood, RH. Post-initiation effects of chlorophyllin and indole-3-carbinol in rats given 1,2-dimethylhydrazine or 2-amino-3-methylimidazo[4,5-f]quinoline. Carcinogenesis 2001;22:309-14.
    • (2001) Carcinogenesis , vol.22 , pp. 309-314
    • Xu, M.1    Orner, G.A.2    Bailey, G.S.3    Stoner, G.D.4    Horio, D.T.5    Dashwood, R.H.6
  • 13
    • 0036119630 scopus 로고    scopus 로고
    • Development of a multi-organ rat model for evaluating chemopreventive agents: Efficacy if indole-3-carbinol
    • Stoner G, Casto B, Ralston S, Roebuck B, Pereira C, Bailey G. Development of a multi-organ rat model for evaluating chemopreventive agents: efficacy if indole-3-carbinol. Carcinogenesis 2002;23:265-72.
    • (2002) Carcinogenesis , vol.23 , pp. 265-272
    • Stoner, G.1    Casto, B.2    Ralston, S.3    Roebuck, B.4    Pereira, C.5    Bailey, G.6
  • 14
    • 8844252309 scopus 로고    scopus 로고
    • Dietary indole-3-carbinol promotes endometrial adenocarcinoma development in rats initiated with N-ethyl-N′-nitro-N-nitrosoguanidine, with induction of cytochrome P450s in the liver and consequent modulation of estrogen metabolism
    • Yoshida M, Katashima S, Ando J, et al. Dietary indole-3-carbinol promotes endometrial adenocarcinoma development in rats initiated with N-ethyl-N′-nitro-N-nitrosoguanidine, with induction of cytochrome P450s in the liver and consequent modulation of estrogen metabolism. Carcinogenesis 2004;25:2257-64.
    • (2004) Carcinogenesis , vol.25 , pp. 2257-2264
    • Yoshida, M.1    Katashima, S.2    Ando, J.3
  • 15
    • 32544432051 scopus 로고    scopus 로고
    • Indole-3-carbinol, but not its major digestive product 3,3′- diindolylmethane, induces reversible hepatocyte hypertrophy and cytochromes P450
    • Crowell JA, Page JG, Levine BS, Tomlinson MJ, Hebert CD. Indole-3-carbinol, but not its major digestive product 3,3′- diindolylmethane, induces reversible hepatocyte hypertrophy and cytochromes P450. Toxicol Appl Pharmacol 2006;211:115-23.
    • (2006) Toxicol Appl Pharmacol , vol.211 , pp. 115-123
    • Crowell, J.A.1    Page, J.G.2    Levine, B.S.3    Tomlinson, M.J.4    Hebert, C.D.5
  • 16
    • 0032822027 scopus 로고    scopus 로고
    • Chemoprevention of breast cancer
    • Osborne MP. Chemoprevention of breast cancer. Surg Clin North Am 1999;79:1207-21.
    • (1999) Surg Clin North Am , vol.79 , pp. 1207-1221
    • Osborne, M.P.1
  • 17
    • 0033648850 scopus 로고    scopus 로고
    • Clinical development of estrogen modulators for breast cancer chemoprevention in premenopausal and postmenopausal women
    • Lawrence JA, Malpas PB, Sigman CC, Kelloff GJ. Clinical development of estrogen modulators for breast cancer chemoprevention in premenopausal and postmenopausal women. J Cell Biochem Suppl 2000;34:103-14.
    • (2000) J Cell Biochem Suppl , vol.34 , pp. 103-114
    • Lawrence, J.A.1    Malpas, P.B.2    Sigman, C.C.3    Kelloff, G.J.4
  • 19
    • 0031401942 scopus 로고    scopus 로고
    • Wong GYC, Bradlow L, Sepkovic D, Mehl S, Mailman J, Osborne MP. Dose-ranging study of indole-3-carbinol for breast cancer prevention. J Cell Biochem 1997;Supplements 28/29:111-6.
    • Wong GYC, Bradlow L, Sepkovic D, Mehl S, Mailman J, Osborne MP. Dose-ranging study of indole-3-carbinol for breast cancer prevention. J Cell Biochem 1997;Supplements 28/29:111-6.
  • 20
    • 0026591316 scopus 로고
    • Oligomerization of indole-3-carbinol in aqueous acid
    • Grose KR, Bjeldanes LF. Oligomerization of indole-3-carbinol in aqueous acid. Chem Res Toxicol 1992;5:188-93.
    • (1992) Chem Res Toxicol , vol.5 , pp. 188-193
    • Grose, K.R.1    Bjeldanes, L.F.2
  • 21
    • 23844450586 scopus 로고    scopus 로고
    • A phase I study of indole-3-carbinol in women: Tolerability and effects
    • Reed GA, Peterson KS, Smith HJ, et al. A phase I study of indole-3-carbinol in women: tolerability and effects. Cancer Epidemiol Biomarkers Prev 2005;14:1953-60.
    • (2005) Cancer Epidemiol Biomarkers Prev , vol.14 , pp. 1953-1960
    • Reed, G.A.1    Peterson, K.S.2    Smith, H.J.3
  • 22
    • 0024801278 scopus 로고
    • Projecting the individualized probabilities of developing breast cancer for white females who are being examined annually
    • Gail MH, Brinton LA, Byar DP, et al. Projecting the individualized probabilities of developing breast cancer for white females who are being examined annually. J Natl Cancer Inst 1989;81:1879-86.
    • (1989) J Natl Cancer Inst , vol.81 , pp. 1879-1886
    • Gail, M.H.1    Brinton, L.A.2    Byar, D.P.3
  • 24
    • 4143051307 scopus 로고    scopus 로고
    • Pharmacokinetics and tissue disposition of indole-3-carbinol and its acid condensation products after oral administration to mice
    • Anderton MJ, Manson MM, Verschoyle RD, et al. Pharmacokinetics and tissue disposition of indole-3-carbinol and its acid condensation products after oral administration to mice. Clin Cancer Res 2004;10:5233-41.
    • (2004) Clin Cancer Res , vol.10 , pp. 5233-5241
    • Anderton, M.J.1    Manson, M.M.2    Verschoyle, R.D.3
  • 25
    • 0031802251 scopus 로고    scopus 로고
    • High basal gastric acid secretion in somatostatin receptor subtype 2 knockout mice
    • Martinez V, Curi AP, Torkian B, et al. High basal gastric acid secretion in somatostatin receptor subtype 2 knockout mice. Gastroenterology 1998;114:1125-32.
    • (1998) Gastroenterology , vol.114 , pp. 1125-1132
    • Martinez, V.1    Curi, A.P.2    Torkian, B.3
  • 26
    • 25444469389 scopus 로고    scopus 로고
    • L-Type amino acids stimulate gastric acid secretion by activation of the calcium-sensing receptor in parietal cells
    • Busque SM, Kerstetter JE, Geibel JP, Insogna K. L-Type amino acids stimulate gastric acid secretion by activation of the calcium-sensing receptor in parietal cells. Am J Physiol Gastrointest Liver Physiol 2005;289:G664-9.
    • (2005) Am J Physiol Gastrointest Liver Physiol , vol.289
    • Busque, S.M.1    Kerstetter, J.E.2    Geibel, J.P.3    Insogna, K.4
  • 27
    • 0344231143 scopus 로고    scopus 로고
    • Regulation of gastrointestical function
    • 20th ed. New York: Lange Medical Books/McGraw-Hill;
    • Ganong WF. Regulation of gastrointestical function. In: Review of medical physiology. 20th ed. New York: Lange Medical Books/McGraw-Hill; 2001. p. 476.
    • (2001) Review of medical physiology , pp. 476
    • Ganong, W.F.1
  • 28
    • 33645464056 scopus 로고    scopus 로고
    • Fate of 3,3′-diindolylmethane in cultured MCF-7 human breast cancer cells
    • Staub RE, Onisko B, Bjeldanes LF. Fate of 3,3′-diindolylmethane in cultured MCF-7 human breast cancer cells. Chem Res Toxicol 2006;19:436-42.
    • (2006) Chem Res Toxicol , vol.19 , pp. 436-442
    • Staub, R.E.1    Onisko, B.2    Bjeldanes, L.F.3
  • 29
    • 2442672870 scopus 로고    scopus 로고
    • Physiological modeling of formulated and crystalline 3,3′-diindolylmethane pharmacokinetics following oral administration in mice
    • Anderton MJ, Manson MM, Verschoyle R, et al. Physiological modeling of formulated and crystalline 3,3′-diindolylmethane pharmacokinetics following oral administration in mice. Drug Metab Dispos 2004;32:632-8.
    • (2004) Drug Metab Dispos , vol.32 , pp. 632-638
    • Anderton, M.J.1    Manson, M.M.2    Verschoyle, R.3
  • 30
    • 2442689845 scopus 로고    scopus 로고
    • New formulation strategies for bioavailability enhancement of two poorly absorbed phytonutrient supplements: Diindolylmethane and yohimbine bark extract
    • Jacobs IC, Zeligs MA. New formulation strategies for bioavailability enhancement of two poorly absorbed phytonutrient supplements: diindolylmethane and yohimbine bark extract. Proc Int Symp Control Rel Bioact Mater 2000;27:1324-5.
    • (2000) Proc Int Symp Control Rel Bioact Mater , vol.27 , pp. 1324-1325
    • Jacobs, I.C.1    Zeligs, M.A.2
  • 31
    • 0036380758 scopus 로고    scopus 로고
    • Improvement of the bioavailability if colchicines in rats by co-administration of D-α-tocopherol polyethylene glycol 1000 succinate and a polyethoxylated derivative of 12-hydroxy-stearic acid
    • Bittner B, Guenzi A, Fullhardt P, et al. Improvement of the bioavailability if colchicines in rats by co-administration of D-α-tocopherol polyethylene glycol 1000 succinate and a polyethoxylated derivative of 12-hydroxy-stearic acid. Arzneimittelforschung 2002;52:684-8.
    • (2002) Arzneimittelforschung , vol.52 , pp. 684-688
    • Bittner, B.1    Guenzi, A.2    Fullhardt, P.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.