Pharmacokinetics and tissue disposition of indole-3-carbinol and its acid condensation products after oral administration to mice

Clinical Cancer Research

Volumn 10, Issue 15, 2004, Pages 5233-5241

  Anderton, Mark J ^a   Manson, Margaret M ^a,c   Verschoyle, Richard D ^a   Gescher, Andreas ^a   Lamb, John H ^a   Farmer, Peter B ^a   Steward, William P ^a   Williams, Marion L ^b  

^a UNIVERSITY OF LEICESTER   (United Kingdom)

^b NATIONAL INSTITUTE ON AGING   (United States)

^c Biocentre   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

1 (3 HYDROXYMETHYL)INDOLYL 3 INDOLYLMETHANE; 3 INDOLECARBALDEHYDE; 3 INDOLECARBOXYLIC ACID; 3 INDOLEMETHANOL; 3,3' DIINDOLYLMETHANE; [2 (INDOL 3 YLMETHYL)INDOL 3 YL]INDOL 3 YLMETHANE; CARBAZOLE DERIVATIVE; CARBOXYLIC ACID; INDOLE DERIVATIVE; INDOLO[3,2B]CARBAZOLE; METHANE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD; BRAIN; CANCER PREVENTION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DISEASE MODEL; DOSE TIME EFFECT RELATION; DRUG ABSORPTION; DRUG BLOOD LEVEL; DRUG DISPOSITION; DRUG DISTRIBUTION; DRUG ELIMINATION; DRUG MECHANISM; FEMALE; HEART; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IN VIVO STUDY; KIDNEY; LIVER; LUNG; METABOLITE; MOUSE; NONHUMAN; POLYMERIZATION; PRIORITY JOURNAL; TISSUE DISTRIBUTION; TISSUE PERFUSION;

ADMINISTRATION, ORAL; ANIMALS; ANTICARCINOGENIC AGENTS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CHROMATOGRAPHY, LIQUID; FEMALE; FREE RADICAL SCAVENGERS; INDOLES; LIVER; MICE; MODELS, CHEMICAL; OXYGEN; PERFUSION; TIME FACTORS; TISSUE DISTRIBUTION;

EID: 4143051307     PISSN: 10780432     EISSN: None     Source Type: Journal    
DOI: 10.1158/1078-0432.CCR-04-0163     Document Type: Article

References (45)

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