Cyclopamine inhibition of human breast cancer cell growth independent of Smoothened (Smo)

Breast Cancer Research and Treatment

Volumn 115, Issue 3, 2009, Pages 505-521

  Zhang, Xiaomei ^a   Harrington, Nikesha ^a   Moraes, Ricardo C ^a   Wu, Meng Fen ^a   Hilsenbeck, Susan G ^a   Lewis, Michael T ^a  

^a BAYLOR COLLEGE OF MEDICINE   (United States)

Author keywords

Breast cancer treatment; Hedgehog signaling; Mammary cancer; Targeted therapy

Indexed keywords

ANTINEOPLASTIC AGENT; CUR 0199691; CYCLOPAMINE; ESTROGEN RECEPTOR; SMOOTHENED PROTEIN; TOMATIDINE; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; BREAST CANCER; CANCER CELL CULTURE; CANCER GROWTH; CANCER INHIBITION; CELL PROLIFERATION; CONTROLLED STUDY; DOSE RESPONSE; DRUG MECHANISM; GROWTH INHIBITION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION;

APOPTOSIS; BINDING, COMPETITIVE; BREAST NEOPLASMS; CELL ADHESION; CELL LINE, TUMOR; CELL PROLIFERATION; CHOLESTEROL; DRUG RESISTANCE, NEOPLASM; FEMALE; FLOW CYTOMETRY; FLUORESCENT ANTIBODY TECHNIQUE; GENE EXPRESSION REGULATION, NEOPLASTIC; HEDGEHOG PROTEINS; HUMANS; RECEPTORS, ESTROGEN; RECEPTORS, G-PROTEIN-COUPLED; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SIGNAL TRANSDUCTION; VERATRUM ALKALOIDS;

EID: 67349224197     PISSN: 01676806     EISSN: 15737217     Source Type: Journal    
DOI: 10.1007/s10549-008-0093-3     Document Type: Article

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