-
1
-
-
0032770514
-
Selective regulation of G protein-coupled receptor-mediated signaling by G protein-coupled receptor kinase 2 in FRTL-5 cells: Analysis of thyrotropin, alpha(1B)-adrenergic, and A(1) adenosine receptor-mediated responses
-
Iacovelli L, Franchetti R, Grisolia D, De Blasi A. Selective regulation of G protein-coupled receptor-mediated signaling by G protein-coupled receptor kinase 2 in FRTL-5 cells: analysis of thyrotropin, alpha(1B)-adrenergic, and A(1) adenosine receptor-mediated responses. Mol Pharmacol. 1999 56 : 316 24.
-
(1999)
Mol Pharmacol.
, vol.56
, pp. 316-24
-
-
Iacovelli, L.1
Franchetti, R.2
Grisolia, D.3
De Blasi, A.4
-
2
-
-
0037799206
-
Keeping G proteins at bay: A complex between G protein-coupled receptor kinase 2 and Gbetagamma
-
Lodowski DT, Pitcher JA, Capel WD, Lefkowitz RJ, Tesmer JJ. Keeping G proteins at bay: a complex between G protein-coupled receptor kinase 2 and Gbetagamma. Science. 2003 300 : 1256 62.
-
(2003)
Science.
, vol.300
, pp. 1256-62
-
-
Lodowski, D.T.1
Pitcher, J.A.2
Capel, W.D.3
Lefkowitz, R.J.4
Tesmer, J.J.5
-
3
-
-
0033605584
-
Regulation of G protein-coupled receptor kinases by caveolin
-
Carman CV, Lisanti MP, Benovic JL. Regulation of G protein-coupled receptor kinases by caveolin. J Biol Chem. 1999 274 : 8858 64.
-
(1999)
J Biol Chem.
, vol.274
, pp. 8858-64
-
-
Carman, C.V.1
Lisanti, M.P.2
Benovic, J.L.3
-
4
-
-
33750617659
-
Overexpression of GRK2 in Alzheimer disease and in a chronic hypoperfusion rat model is an early marker of brain mitochondrial lesions
-
Obrenovich ME, Smith MA, Siedlak SL, Chen SG, de la Torre JC, Perry G, Aliev G. Overexpression of GRK2 in Alzheimer disease and in a chronic hypoperfusion rat model is an early marker of brain mitochondrial lesions. Neurotox Res. 2006 10 : 43 56.
-
(2006)
Neurotox Res.
, vol.10
, pp. 43-56
-
-
Obrenovich, M.E.1
Smith, M.A.2
Siedlak, S.L.3
Chen, S.G.4
De La Torre, J.C.5
Perry, G.6
Aliev, G.7
-
5
-
-
47549115789
-
What initiates the formation of senile plaques? the origin of Alzheimerlike dementias in capillary haemorrhages
-
Stone J. What initiates the formation of senile plaques? The origin of Alzheimerlike dementias in capillary haemorrhages. Med Hypotheses. 2008 71 : 347 59.
-
(2008)
Med Hypotheses.
, vol.71
, pp. 347-59
-
-
Stone, J.1
-
6
-
-
0033974885
-
A unifying hypothesis of Alzheimer's disease. III. Risk factors
-
DOI 10.1002/(SICI)1099-1077(200001)15:1<1::AID-HUP153>3.0.CO;2-1
-
Heininger K. A unifying hypothesis of Alzheimer's disease. III. Risk factors. Hum Psychopharmacol. 2000 15 : 1 70. (Pubitemid 30095420)
-
(2000)
Human Psychopharmacology
, vol.15
, Issue.1
, pp. 1-70
-
-
Heininger, K.1
-
7
-
-
0036591850
-
Interactions of oxidative stress with cellular calcium dynamics and glucose metabolism in Alzheimer's disease
-
Gibson GE. Interactions of oxidative stress with cellular calcium dynamics and glucose metabolism in Alzheimer's disease. Free Radic Biol Med. 2002 32 : 1061 70.
-
(2002)
Free Radic Biol Med.
, vol.32
, pp. 1061-70
-
-
Gibson, G.E.1
-
8
-
-
1342285214
-
Role of vascular hypoperfusion-induced oxidative stress and mitochondria failure in the pathogenesis of Azheimer disease
-
Aliev G, Smith MA, Obrenovich ME, de la Torre JC, Perry G. Role of vascular hypoperfusion-induced oxidative stress and mitochondria failure in the pathogenesis of Azheimer disease. Neurotox Res. 2003 5 : 491 504.
-
(2003)
Neurotox Res.
, vol.5
, pp. 491-504
-
-
Aliev, G.1
Smith, M.A.2
Obrenovich, M.E.3
De La Torre, J.C.4
Perry, G.5
-
9
-
-
0036449696
-
Atherosclerotic lesions and mitochondria DNA deletions in brain microvessels as a central target for the development of human AD and AD-like pathology in aged transgenic mice
-
Aliev G, Seyidova D, Neal ML, Shi J, Lamb BT, Siedlak SL, Vinters HV, Head E, Perry G, Lamanna JC, Friedland RP, Cotman CW. Atherosclerotic lesions and mitochondria DNA deletions in brain microvessels as a central target for the development of human AD and AD-like pathology in aged transgenic mice. Ann N Y Acad Sci. 2002 977 : 45 64. (Pubitemid 35418136)
-
(2002)
Annals of the New York Academy of Sciences
, vol.977
, pp. 45-64
-
-
Aliev, G.1
Seyidova, D.2
Neal, M.L.3
Shi, J.4
Lamb, B.T.5
Siedlak, S.L.6
Vinters, H.V.7
Head, E.8
Perry, G.9
Lamanna, J.C.10
Friedland, R.P.11
Cotman, C.W.12
-
10
-
-
0036133115
-
The role of oxidative stress in the pathophysiology of cerebrovascular lesions in Alzheimer's disease
-
Aliev G, Smith MA, Seyidov D, Neal ML, Lamb BT, Nunomura A, Gasimov EK, Vinters HV, Perry G, LaManna JC, Friedland R P. The role of oxidative stress in the pathophysiology of cerebrovascular lesions in Alzheimer's disease. Brain Pathol. 2002 12 : 21 35. (Pubitemid 33131359)
-
(2002)
Brain Pathology
, vol.12
, Issue.1
, pp. 21-35
-
-
Aliev, G.1
Smith, M.A.2
Seyidova, D.3
Neal, M.L.4
Lamb, B.T.5
Nunomura, A.6
Gasimov, E.K.7
Vinters, H.V.8
Perry, G.9
Lamanna, J.C.10
Friedland, R.P.11
-
11
-
-
33746565284
-
Apolipoprotein E, cholesterol metabolism, diabetes, and the convergence of risk factors for Alzheimer's disease and cardiovascular disease
-
Martins IJ, Hone E, Foster JK, Sunram-Lea SI, Gnjec A, Fuller SJ, Nolan D, Gandy SE, Martins RN. Apolipoprotein E, cholesterol metabolism, diabetes, and the convergence of risk factors for Alzheimer's disease and cardiovascular disease. Mol Psychiatry. 2006 11 : 721 36.
-
(2006)
Mol Psychiatry.
, vol.11
, pp. 721-36
-
-
Martins, I.J.1
Hone, E.2
Foster, J.K.3
Sunram-Lea, S.I.4
Gnjec, A.5
Fuller, S.J.6
Nolan, D.7
Gandy, S.E.8
Martins, R.N.9
-
12
-
-
34249776958
-
Vascular oxidative stress in Alzheimer disease
-
Zhu X, Smith MA, Honda K, Aliev G, Moreira PI, Nunomura A, Casadesus G, Harris PL, Siedlak SL, Perry G. Vascular oxidative stress in Alzheimer disease. J Neurol Sci. 2007 257 : 240 6.
-
(2007)
J Neurol Sci.
, vol.257
, pp. 240-6
-
-
Zhu, X.1
Smith, M.A.2
Honda, K.3
Aliev, G.4
Moreira, P.I.5
Nunomura, A.6
Casadesus, G.7
Harris, P.L.8
Siedlak, S.L.9
Perry, G.10
-
13
-
-
0029670896
-
Alterations in angiotensin AT1 and AT2 receptor subtype levels in brain regions from patients with neurodegenerative disorders
-
Ge J, Barnes NM. Alterations in angiotensin AT1 and AT2 receptor subtype levels in brain regions from patients with neurodegenerative disorders. Eur J Pharmacol. 1996 297 : 299 306.
-
(1996)
Eur J Pharmacol.
, vol.297
, pp. 299-306
-
-
Ge, J.1
Barnes, N.M.2
-
14
-
-
1842506382
-
Abnormality of G-protein-cou-pled receptor kinases at prodromal and early stages of Alzheimer's disease: An association with early beta-amyloid accumulation
-
Suo Z, Wu M, Citron BA, Wong GT, Festoff BW. Abnormality of G-protein-cou-pled receptor kinases at prodromal and early stages of Alzheimer's disease: an association with early beta-amyloid accumulation. J Neurosci. 2004 24 : 3444 52.
-
(2004)
J Neurosci.
, vol.24
, pp. 3444-52
-
-
Suo, Z.1
Wu, M.2
Citron, B.A.3
Wong, G.T.4
Festoff, B.W.5
-
15
-
-
67249089661
-
Protective effect of acetyl-L-carnitine and R-lipoic acid treatment in ApoE4 mouse as a model of human Alzheimer's disease
-
e-pub ahead of print. in press.
-
Shenk JC, Liu J, Fischbach K, Xu K, Puchowicz M, Obrenovich ME, Gasimov E, Ames BN, LaManna JC, Aliev G. Protective effect of acetyl-L-carnitine and R-lipoic acid treatment in ApoE4 mouse as a model of human Alzheimer's disease. J Neurolog Sci. 2009 e-pub ahead of print in press.
-
(2009)
J Neurolog Sci.
-
-
Shenk, J.C.1
Liu, J.2
Fischbach, K.3
Xu, K.4
Puchowicz, M.5
Obrenovich, M.E.6
Gasimov, E.7
Ames, B.N.8
Lamanna, J.C.9
Aliev, G.10
-
16
-
-
0346034895
-
Differential G protein receptor kinase 2 expression in compensated hypertrophy and heart failure after myocardial infarction in the rat
-
DOI 10.1007/s00395-003-0395-x
-
Theilade J, Strom C, Christiansen T, Haunso S, Sheikh SP. Differential G protein receptor kinase 2 expression in compensated hypertrophy and heart failure after myocardial infarction in the rat. Basic Res Cardiol. 2003 98 : 97 103. (Pubitemid 36342311)
-
(2003)
Basic Research in Cardiology
, vol.98
, Issue.2
, pp. 97-103
-
-
Theilade, J.1
Strom, C.2
Christiansen, T.3
Haunso, S.4
Sheikh, S.P.5
-
17
-
-
0345451057
-
Role of G protein-coupled receptor kinase 2 and arrestins in beta-adrenergic receptor inter-nalization
-
Mayor F Jr., Penela P, Ruiz-Gomez A. Role of G protein-coupled receptor kinase 2 and arrestins in beta-adrenergic receptor inter-nalization. Trends Cardiovasc Med. 1998 8 : 234 40.
-
(1998)
Trends Cardiovasc Med.
, vol.8
, pp. 234-40
-
-
Mayor Jr., F.1
Penela, P.2
Ruiz-Gomez, A.3
-
19
-
-
0026658663
-
The G-protein-coupled receptor kinases beta ARK1 and beta ARK2 are widely distributed at synapses in rat brain
-
Arriza JL, Dawson TM, Simerly RB, Martin LJ, Caron MG, Snyder SH, Lefkowitz RJ. The G-protein-coupled receptor kinases beta ARK1 and beta ARK2 are widely distributed at synapses in rat brain. J Neurosci. 1992 12 : 4045 55.
-
(1992)
J Neurosci.
, vol.12
, pp. 4045-55
-
-
Arriza, J.L.1
Dawson, T.M.2
Simerly, R.B.3
Martin, L.J.4
Caron, M.G.5
Snyder, S.H.6
Lefkowitz, R.J.7
-
20
-
-
0035500377
-
Distribution of G-protein-coupled receptor kinase (GRK) isoforms 2, 3, 5 and 6 mRNA in the rat brain
-
Erdtmann-Vourliotis M, Mayer P, Ammon S, Riechert U, Hollt V. Distribution of G-protein-coupled receptor kinase (GRK) isoforms 2, 3, 5 and 6 mRNA in the rat brain. Brain Res Mol Brain Res. 2001 95 : 129 37.
-
(2001)
Brain Res Mol Brain Res.
, vol.95
, pp. 129-37
-
-
Erdtmann-Vourliotis, M.1
Mayer, P.2
Ammon, S.3
Riechert, U.4
Hollt, V.5
-
21
-
-
0141582501
-
Expression patterns of the regulatory proteins G protein-coupled receptor kinase 2 and beta-arrestin 1 during rat postnatal brain development: Effect of hypothyroidism
-
Penela P, Alvarez-Dolado M, Munoz A, Mayor F Jr. Expression patterns of the regulatory proteins G protein-coupled receptor kinase 2 and beta-arrestin 1 during rat postnatal brain development: effect of hypothyroidism. Eur J Biochem. 2000 267 : 4390 6.
-
(2000)
Eur J Biochem.
, vol.267
, pp. 4390-6
-
-
Penela, P.1
Alvarez-Dolado, M.2
Munoz, A.3
Mayor Jr., F.4
-
22
-
-
24344482275
-
Alzheimer disease - A new beginning, or a final exit?
-
In. Nicoletti, F. Copani, A. editors. Austin, TX. Landes Biosciences. pp.
-
Obrenovich ME, Raina AK, Ogawa O, Atwood CS, Smith MA. Alzheimer disease - a new beginning, or a final exit? In : Nicoletti F, Copani A, editors. Cell-cycle mechanisms in neuronal death. Austin, TX : Landes Biosciences 2003. pp. 71 90.
-
(2003)
Cell-cycle Mechanisms in Neuronal Death.
, pp. 71-90
-
-
Obrenovich, M.E.1
Raina, A.K.2
Ogawa, O.3
Atwood, C.S.4
Smith, M.A.5
-
23
-
-
33645681674
-
Oncogenic parallels in Alzheimer disease
-
Raina AK, Garret MG, Previll LA, Obrenovich ME, Hartzler AW, Webber KM, Casadesus G, Lee H, Perry G, Zhu X, Smith MA. Oncogenic parallels in Alzheimer disease. Int. J. Neuroprot. Neurodegeneration. 2006 2 : 80 5.
-
(2006)
Int. J. Neuroprot. Neurodegeneration.
, vol.2
, pp. 80-5
-
-
Raina, A.K.1
Garret, M.G.2
Previll, L.A.3
Obrenovich, M.E.4
Hartzler, A.W.5
Webber, K.M.6
Casadesus, G.7
Lee, H.8
Perry, G.9
Zhu, X.10
Smith, M.A.11
-
24
-
-
67249085266
-
Alzheimer disease: A new beginning or a final exit?
-
In. Copani, A. Nicoletti, F. editors. Austin, TX. Landes Biosciences. pp.
-
Obrenovich MA, Raina AK, Ogawa O, Atwood CS, Morelli L, Smith MA. Alzheimer disease: a new beginning or a final exit? In : Copani A, Nicoletti F, editors. Cell cycle activation and cell death in the nervous system. Austin, TX : Landes Biosciences 2005. pp. 1 15.
-
(2005)
Cell Cycle Activation and Cell Death in the Nervous System.
, pp. 1-15
-
-
Obrenovich, M.A.1
Raina, A.K.2
Ogawa, O.3
Atwood, C.S.4
Morelli, L.5
Smith, M.A.6
-
25
-
-
2942666557
-
Phosphorylation of G protein-coupled receptors: GPCR kinases in heart disease
-
Hata JA, Koch WJ. Phosphorylation of G protein-coupled receptors: GPCR kinases in heart disease. Mol Interv. 2003 3 : 264 72.
-
(2003)
Mol Interv.
, vol.3
, pp. 264-72
-
-
Hata, J.A.1
Koch, W.J.2
-
26
-
-
0029798741
-
Activation of beta-adrenergic receptor kinase during myocardial ischemia
-
Ungerer M, Kessebohm K, Kronsbein K, Lohse MJ, Richardt G. Activation of beta-adrenergic receptor kinase during myocardial ischemia. Circ Res. 1996 79 : 455 60.
-
(1996)
Circ Res.
, vol.79
, pp. 455-60
-
-
Ungerer, M.1
Kessebohm, K.2
Kronsbein, K.3
Lohse, M.J.4
Richardt, G.5
-
27
-
-
0030798818
-
Mechanism of beta-adrenergic receptor desensitization in cardiac hypertrophy is increased beta-adrenergic receptor kinase
-
Choi DJ, Koch WJ, Hunter JJ, Rockman HA. Mechanism of beta-adrenergic receptor desensitization in cardiac hypertrophy is increased beta-adrenergic receptor kinase. J Biol Chem. 1997 272 : 17223 9.
-
(1997)
J Biol Chem.
, vol.272
, pp. 17223-9
-
-
Choi, D.J.1
Koch, W.J.2
Hunter, J.J.3
Rockman, H.A.4
-
28
-
-
0034927256
-
Expression of GRK2 is increased in the left ventricles of cardiomyopathic hamsters
-
Harris CA, Chuang TT, Scorer CA. Expression of GRK2 is increased in the left ventricles of cardiomyopathic hamsters. Basic Res Cardiol. 2001 96 : 364 8.
-
(2001)
Basic Res Cardiol.
, vol.96
, pp. 364-8
-
-
Harris, C.A.1
Chuang, T.T.2
Scorer, C.A.3
-
29
-
-
3142514666
-
Alterations of beta-adrenoceptor responsiveness in postischemic myocardium after 72 h of reperfusion
-
Boucher M, Nim S, de Montigny C, Rousseau G. Alterations of beta-adrenoceptor responsiveness in postischemic myocardium after 72 h of reperfusion. Eur J Pharmacol. 2004 495 : 185 91.
-
(2004)
Eur J Pharmacol.
, vol.495
, pp. 185-91
-
-
Boucher, M.1
Nim, S.2
De Montigny, C.3
Rousseau, G.4
-
30
-
-
0037315299
-
Cardiopulmonary bypass decreases G protein-coupled receptor kinase activity and expression in human peripheral blood mononuclear cells
-
Hagen SA, Kondyra AL, Grocott HP, El-Moalem H, Bainbridge D, Mathew JP, Newman MF, Reves JG, Schwinn DA, Kwatra MM. Cardiopulmonary bypass decreases G protein-coupled receptor kinase activity and expression in human peripheral blood mononuclear cells. Anesthesiology. 2003 98 : 343 8.
-
(2003)
Anesthesiology.
, vol.98
, pp. 343-8
-
-
Hagen, S.A.1
Kondyra, A.L.2
Grocott, H.P.3
El-Moalem, H.4
Bainbridge, D.5
Mathew, J.P.6
Newman, M.F.7
Reves, J.G.8
Schwinn, D.A.9
Kwatra, M.M.10
-
31
-
-
0034595227
-
Analysis of the human G protein-coupled receptor kinase 2 (GRK2) gene promoter: Regulation by signal transduction systems in aortic smooth muscle cells
-
Ramos-Ruiz R, Penela P, Penn RB, Mayor F Jr. Analysis of the human G protein-coupled receptor kinase 2 (GRK2) gene promoter: regulation by signal transduction systems in aortic smooth muscle cells. Circulation. 2000 101 : 2083 9.
-
(2000)
Circulation.
, vol.101
, pp. 2083-9
-
-
Ramos-Ruiz, R.1
Penela, P.2
Penn, R.B.3
Mayor Jr., F.4
-
32
-
-
24744444714
-
A crucial role for GRK2 in regulation of endothelial cell nitric oxide synthase function in portal hypertension
-
Liu S, Premont RT, Kontos CD, Zhu S, Rockey DC. A crucial role for GRK2 in regulation of endothelial cell nitric oxide synthase function in portal hypertension. Nat Med. 2005 11 : 952 8.
-
(2005)
Nat Med.
, vol.11
, pp. 952-8
-
-
Liu, S.1
Premont, R.T.2
Kontos, C.D.3
Zhu, S.4
Rockey, D.C.5
-
33
-
-
24044543283
-
Elevated myocar-dial and lymphocyte GRK2 expression and activity in human heart failure
-
Iaccarino G, Barbato E, Cipolletta E, De Amicis V, Margulies KB, Leosco D, Trimarco B, Koch WJ. Elevated myocar-dial and lymphocyte GRK2 expression and activity in human heart failure. Eur Heart J. 2005 26 : 1752 8.
-
(2005)
Eur Heart J.
, vol.26
, pp. 1752-8
-
-
Iaccarino, G.1
Barbato, E.2
Cipolletta, E.3
De Amicis, V.4
Margulies, K.B.5
Leosco, D.6
Trimarco, B.7
Koch, W.J.8
-
34
-
-
0029884416
-
Identification of the G protein-coupled receptor kinase phosphorylation sites in the human beta2-adrenergic receptor
-
Fredericks ZL, Pitcher JA, Lefkowitz RJ. Identification of the G protein-coupled receptor kinase phosphorylation sites in the human beta2-adrenergic receptor. J Biol Chem. 1996 271 : 13796 803.
-
(1996)
J Biol Chem.
, vol.271
, pp. 13796-803
-
-
Fredericks, Z.L.1
Pitcher, J.A.2
Lefkowitz, R.J.3
-
35
-
-
0035101820
-
Evolving concepts in G protein-coupled receptor endocytosis: The role in receptor desensitization and signaling
-
Ferguson SS. Evolving concepts in G protein-coupled receptor endocytosis: the role in receptor desensitization and signaling. Pharmacol Rev. 2001 53 : 1 24. (Pubitemid 32173106)
-
(2001)
Pharmacological Reviews
, vol.53
, Issue.1
, pp. 1-24
-
-
Ferguson, S.S.G.1
-
36
-
-
0033521109
-
Feedback inhibition of G protein-coupled receptor kinase 2 (GRK2) activity by extracellular signal-regulated kinases
-
Pitcher JA, Tesmer JJ, Freeman JL, Capel WD, Stone WC, Lefkowitz RJ. Feedback inhibition of G protein-coupled receptor kinase 2 (GRK2) activity by extracellular signal-regulated kinases. J Biol Chem. 1999 274 : 34531 4.
-
(1999)
J Biol Chem.
, vol.274
, pp. 34531-4
-
-
Pitcher, J.A.1
Tesmer, J.J.2
Freeman, J.L.3
Capel, W.D.4
Stone, W.C.5
Lefkowitz, R.J.6
-
37
-
-
4344632193
-
Transgenic mice targeting the heart unveil G protein-coupled receptor kinases as therapeutic targets
-
Iaccarino G, Koch WJ. Transgenic mice targeting the heart unveil G protein-coupled receptor kinases as therapeutic targets. Assay Drug Dev Technol. 2003 1 : 347 55.
-
(2003)
Assay Drug Dev Technol.
, vol.1
, pp. 347-55
-
-
Iaccarino, G.1
Koch, W.J.2
-
38
-
-
34547114525
-
GRK2 negatively regulates glycogen synthesis in mouse liver FL83B cells
-
Shahid G, Hussain T. GRK2 negatively regulates glycogen synthesis in mouse liver FL83B cells. J Biol Chem. 2007 282 : 20612 20.
-
(2007)
J Biol Chem.
, vol.282
, pp. 20612-20
-
-
Shahid, G.1
Hussain, T.2
-
39
-
-
0033607326
-
Selective regulation of Galpha(q-11) by an RGS domain in the G protein-coupled receptor kinase, GRK2
-
Carman CV, Parent JL, Day PW, Pronin AN, Sternweis PM, Wedegaertner PB, Gilman AG, Benovic JL, Kozasa T. Selective regulation of Galpha(q-11) by an RGS domain in the G protein-coupled receptor kinase, GRK2. J Biol Chem. 1999 274 : 34483 92.
-
(1999)
J Biol Chem.
, vol.274
, pp. 34483-92
-
-
Carman, C.V.1
Parent, J.L.2
Day, P.W.3
Pronin, A.N.4
Sternweis, P.M.5
Wedegaertner, P.B.6
Gilman, A.G.7
Benovic, J.L.8
Kozasa, T.9
-
40
-
-
27644433164
-
G protein-coupled receptor kinase 2 mediates endothelin-1-induced insulin resistance via the inhibition of both Galphaq-11 and insulin receptor substrate-1 pathways in 3T3-L1 adipocytes
-
Usui I, Imamura T, Babendure JL, Satoh H, Lu JC, Hupfeld CJ, Olefsky JM. G protein-coupled receptor kinase 2 mediates endothelin-1-induced insulin resistance via the inhibition of both Galphaq-11 and insulin receptor substrate-1 pathways in 3T3-L1 adipocytes. Mol Endocrinol. 2005 19 : 2760 8.
-
(2005)
Mol Endocrinol.
, vol.19
, pp. 2760-8
-
-
Usui, I.1
Imamura, T.2
Babendure, J.L.3
Satoh, H.4
Lu, J.C.5
Hupfeld, C.J.6
Olefsky, J.M.7
-
41
-
-
0032964882
-
Characterization of the carboxyl terminal-truncated endothelin B receptor coexpressed with G protein-coupled receptor kinase 2
-
Shibasaki T, Moroi K, Nishiyama M, Zhou J, Sakamoto A, Masaki T, Ito K, Haga T, Kimura S. Characterization of the carboxyl terminal-truncated endothelin B receptor coexpressed with G protein-coupled receptor kinase 2. Biochem Mol Biol Int. 1999 47 : 569 77.
-
(1999)
Biochem Mol Biol Int.
, vol.47
, pp. 569-77
-
-
Shibasaki, T.1
Moroi, K.2
Nishiyama, M.3
Zhou, J.4
Sakamoto, A.5
Masaki, T.6
Ito, K.7
Haga, T.8
Kimura, S.9
-
42
-
-
0037334111
-
Differential requirement of G alpha12, G alpha13, G alphaq, and G beta gamma for endothelin-1-induced c-Jun NH2-terminal kinase and extracellular signal-regulated kinase activation
-
Arai K, Maruyama Y, Nishida M, Tanabe S, Takagahara S, Kozasa T, Mori Y, Nagao T, Kurose H. Differential requirement of G alpha12, G alpha13, G alphaq, and G beta gamma for endothelin-1-induced c-Jun NH2-terminal kinase and extracellular signal-regulated kinase activation. Mol Pharmacol. 2003 63 : 478 88.
-
(2003)
Mol Pharmacol.
, vol.63
, pp. 478-88
-
-
Arai, K.1
Maruyama, Y.2
Nishida, M.3
Tanabe, S.4
Takagahara, S.5
Kozasa, T.6
Mori, Y.7
Nagao, T.8
Kurose, H.9
-
43
-
-
0029950405
-
Inhibition of myocardial endothelin pathway improves long-term survival in heart failure
-
Sakai S, Miyauchi T, Kobayashi M, Yamaguchi I, Goto K, Sugishita Y. Inhibition of myocardial endothelin pathway improves long-term survival in heart failure. Nature. 1996 384 : 353 5.
-
(1996)
Nature.
, vol.384
, pp. 353-5
-
-
Sakai, S.1
Miyauchi, T.2
Kobayashi, M.3
Yamaguchi, I.4
Goto, K.5
Sugishita, Y.6
-
44
-
-
0036208319
-
Deactivation of vasodilator responses by GRK2 overexpression: A mechanism or the mechanism for hypertension?
-
Feldman RD. Deactivation of vasodilator responses by GRK2 overexpression: a mechanism or the mechanism for hypertension? Mol Pharmacol. 2002 61 : 707 9.
-
(2002)
Mol Pharmacol.
, vol.61
, pp. 707-9
-
-
Feldman, R.D.1
-
45
-
-
0030757504
-
Phosphorylation and desensitization of human endothelin A and B receptors. Evidence for G protein-coupled receptor kinase specificity
-
Freedman NJ, Ament AS, Oppermann M, Stoffel RH, Exum ST, Lefkowitz RJ. Phosphorylation and desensitization of human endothelin A and B receptors. Evidence for G protein-coupled receptor kinase specificity. J Biol Chem. 1997 272 : 17734 43.
-
(1997)
J Biol Chem.
, vol.272
, pp. 17734-43
-
-
Freedman, N.J.1
Ament, A.S.2
Oppermann, M.3
Stoffel, R.H.4
Exum, S.T.5
Lefkowitz, R.J.6
-
46
-
-
0347379916
-
Endothelin-1 activates endothelial cell nitric-oxide synthase via heterotrimeric G-protein betagamma sub-unit signaling to protein kinase B-Akt
-
Liu S, Premont RT, Kontos CD, Huang J, Rockey DC. Endothelin-1 activates endothelial cell nitric-oxide synthase via heterotrimeric G-protein betagamma sub-unit signaling to protein kinase B-Akt. J Biol Chem. 2003 278 : 49929 35.
-
(2003)
J Biol Chem.
, vol.278
, pp. 49929-35
-
-
Liu, S.1
Premont, R.T.2
Kontos, C.D.3
Huang, J.4
Rockey, D.C.5
-
47
-
-
0033607513
-
Agonist-dependent phosphorylation of the G protein-coupled receptor kinase 2 (GRK2) by Src tyrosine kinase
-
Sarnago S, Elorza A, Mayor F Jr. Agonist-dependent phosphorylation of the G protein-coupled receptor kinase 2 (GRK2) by Src tyrosine kinase. J Biol Chem. 1999 274 : 34411 6.
-
(1999)
J Biol Chem.
, vol.274
, pp. 34411-6
-
-
Sarnago, S.1
Elorza, A.2
Mayor Jr., F.3
-
48
-
-
3142552421
-
P38 Mitogen-activated protein kinase regulates vasoconstriction in spontaneously hypertensive rats
-
Kwon S, Fang LH, Kim B, Ha TS, Lee SJ, Ahn HY. p38 Mitogen-activated protein kinase regulates vasoconstriction in spontaneously hypertensive rats. J Pharmacol Sci. 2004 95 : 267 72.
-
(2004)
J Pharmacol Sci.
, vol.95
, pp. 267-72
-
-
Kwon, S.1
Fang, L.H.2
Kim, B.3
Ha, T.S.4
Lee, S.J.5
Ahn, H.Y.6
-
49
-
-
0033516947
-
Activation of neuronal extracellular receptor kinase (ERK) in Alzheimer disease links oxidative stress to abnormal phosphorylation
-
Perry G, Roder H, Nunomura A, Takeda A, Friedlich AL, Zhu X, Raina AK, Holbrook N, Siedlak SL, Harris PL, Smith MA. Activation of neuronal extracellular receptor kinase (ERK) in Alzheimer disease links oxidative stress to abnormal phosphorylation. Neuroreport. 1999 10 : 2411 5.
-
(1999)
Neuroreport.
, vol.10
, pp. 2411-5
-
-
Perry, G.1
Roder, H.2
Nunomura, A.3
Takeda, A.4
Friedlich, A.L.5
Zhu, X.6
Raina, A.K.7
Holbrook, N.8
Siedlak, S.L.9
Harris, P.L.10
Smith, M.A.11
-
50
-
-
0027181221
-
Brain protein kinase PK40erk converts TAU into a PHF-like form as found in Alzheimer's disease
-
Roder HM, Eden PA, Ingram VM. Brain protein kinase PK40erk converts TAU into a PHF-like form as found in Alzheimer's disease. Biochem Biophys Res Commun. 1993 193 : 639 47.
-
(1993)
Biochem Biophys Res Commun.
, vol.193
, pp. 639-47
-
-
Roder, H.M.1
Eden, P.A.2
Ingram, V.M.3
-
51
-
-
0036770144
-
The role of mitogen-activated protein kinase pathways in Alzheimer's disease
-
Zhu X, Lee HG, Raina AK, Perry G, Smith MA. The role of mitogen-activated protein kinase pathways in Alzheimer's disease. Neurosignals. 2002 11 : 270 81.
-
(2002)
Neurosignals.
, vol.11
, pp. 270-81
-
-
Zhu, X.1
Lee, H.G.2
Raina, A.K.3
Perry, G.4
Smith, M.A.5
-
52
-
-
0035027964
-
Abortive apoptosis in Alzheimer's disease
-
Raina AK, Hochman A, Zhu X, Rottkamp CA, Nunomura A, Siedlak SL, Boux H, Castellani RJ, Perry G, Smith MA. Abortive apoptosis in Alzheimer's disease. Acta Neuropathol. 2001 101 : 305 10.
-
(2001)
Acta Neuropathol.
, vol.101
, pp. 305-10
-
-
Raina, A.K.1
Hochman, A.2
Zhu, X.3
Rottkamp, C.A.4
Nunomura, A.5
Siedlak, S.L.6
Boux, H.7
Castellani, R.J.8
Perry, G.9
Smith, M.A.10
-
53
-
-
0042707658
-
MAPK-dependent degradation of G protein-coupled receptor kinase 2
-
Elorza A, Penela P, Sarnago S, Mayor F Jr. MAPK-dependent degradation of G protein-coupled receptor kinase 2. J Biol Chem. 2003 278 : 29164 73.
-
(2003)
J Biol Chem.
, vol.278
, pp. 29164-73
-
-
Elorza, A.1
Penela, P.2
Sarnago, S.3
Mayor Jr., F.4
-
54
-
-
0037401753
-
G protein-coupled receptor kinases regulate metabotropic glutamate receptor 5 function and expression
-
DOI 10.1016/S0028-3908(03)00053-4
-
Sorensen SD, Conn PJ. G protein-coupled receptor kinases regulate metabotropic glutamate receptor 5 function and expression. Neuropharmacology. 2003 44 : 699 706. (Pubitemid 36385135)
-
(2003)
Neuropharmacology
, vol.44
, Issue.6
, pp. 699-706
-
-
Sorensen, S.D.1
Conn, P.J.2
-
55
-
-
0030021780
-
Chronic reduction of cerebral blood flow in the adult rat: Late-emerging CA1 cell loss and memory dysfunction
-
Pappas BA, de la Torre JC, Davidson CM, Keyes MT, Fortin T. Chronic reduction of cerebral blood flow in the adult rat: late-emerging CA1 cell loss and memory dysfunction. Brain Res. 1996 708 : 50 8.
-
(1996)
Brain Res.
, vol.708
, pp. 50-8
-
-
Pappas, B.A.1
De La Torre, J.C.2
Davidson, C.M.3
Keyes, M.T.4
Fortin, T.5
-
56
-
-
0026575915
-
Cerebral blood flow and histopathological changes following permanent bilateral carotid artery ligation in Wistar rats
-
Tsuchiya M, Sako K, Yura S, Yonemasu Y. Cerebral blood flow and histopathological changes following permanent bilateral carotid artery ligation in Wistar rats. Exp Brain Res. 1992 89 : 87 92.
-
(1992)
Exp Brain Res.
, vol.89
, pp. 87-92
-
-
Tsuchiya, M.1
Sako, K.2
Yura, S.3
Yonemasu, Y.4
-
57
-
-
0029022511
-
Correlates between nuclear magnetic resonance spectroscopy, diffusion weighted imaging, and CA1 morphometry following chronic brain ischemia
-
de la Torre JC, Butler K, Kozlowski P, Fortin T, Saunders JK. Correlates between nuclear magnetic resonance spectroscopy, diffusion weighted imaging, and CA1 morphometry following chronic brain ischemia. J Neurosci Res. 1995 41 : 238 45.
-
(1995)
J Neurosci Res.
, vol.41
, pp. 238-45
-
-
De La Torre, J.C.1
Butler, K.2
Kozlowski, P.3
Fortin, T.4
Saunders, J.K.5
-
58
-
-
0026725324
-
Aged but not young rats develop metabolic, memory deficits after chronic brain ischaemia
-
de la Torre JC, Fortin T, Park GA, Saunders JK, Kozlowski P, Butler K, de Socarraz H, Pappas B, Richard M. Aged but not young rats develop metabolic, memory deficits after chronic brain ischaemia. Neurol Res. 1992 14 : 177 80.
-
(1992)
Neurol Res.
, vol.14
, pp. 177-80
-
-
De La Torre, J.C.1
Fortin, T.2
Park, G.A.3
Saunders, J.K.4
Kozlowski, P.5
Butler, K.6
De Socarraz, H.7
Pappas, B.8
Richard, M.9
-
59
-
-
10644276189
-
Mitochondria as a primary target for vascular hypoperfusion and oxidative stress in Alzheimer's disease
-
Aliev G, Smith MA, de la Torre JC, Perry G. Mitochondria as a primary target for vascular hypoperfusion and oxidative stress in Alzheimer's disease. Mitochondrion. 2004 4 : 649 63.
-
(2004)
Mitochondrion.
, vol.4
, pp. 649-63
-
-
Aliev, G.1
Smith, M.A.2
De La Torre, J.C.3
Perry, G.4
-
61
-
-
18944380149
-
Inhibition of vascular nitric oxide after rat chronic brain hypoperfusion: Spatial memory and immunocytochemical changes
-
de la Torre JC, Aliev G. Inhibition of vascular nitric oxide after rat chronic brain hypoperfusion: spatial memory and immunocytochemical changes. J Cereb Blood Flow Metab. 2005 25 : 663 72.
-
(2005)
J Cereb Blood Flow Metab.
, vol.25
, pp. 663-72
-
-
De La Torre, J.C.1
Aliev, G.2
-
62
-
-
0036827161
-
Abeta as a bioflocculant: Implications for the amyloid hypothesis of Alzheimer's disease
-
Robinson SR, Bishop GM. Abeta as a bioflocculant: implications for the amyloid hypothesis of Alzheimer's disease. Neurobiol Aging. 2002 23 : 1051 72.
-
(2002)
Neurobiol Aging.
, vol.23
, pp. 1051-72
-
-
Robinson, S.R.1
Bishop, G.M.2
-
63
-
-
0036834187
-
Amyloid-beta: A (life) preserver for the brain
-
Obrenovich ME, Joseph JA, Atwood CS, Perry G, Smith MA. Amyloid-beta: a (life) preserver for the brain. Neurobiol Aging. 2002 23 : 1097 9.
-
(2002)
Neurobiol Aging.
, vol.23
, pp. 1097-9
-
-
Obrenovich, M.E.1
Joseph, J.A.2
Atwood, C.S.3
Perry, G.4
Smith, M.A.5
-
64
-
-
0345184327
-
Protein kinase and protein phosphatase expression in amyotrophic lateral sclerosis spinal cord
-
Hu JH, Zhang H, Wagey R, Krieger C, Pelech SL. Protein kinase and protein phosphatase expression in amyotrophic lateral sclerosis spinal cord. J Neurochem. 2003 85 : 432 42.
-
(2003)
J Neurochem.
, vol.85
, pp. 432-42
-
-
Hu, J.H.1
Zhang, H.2
Wagey, R.3
Krieger, C.4
Pelech, S.L.5
-
65
-
-
0042387969
-
Vasoactive effects of A beta in isolated human cerebrovessels and in a transgenic mouse model of Alzheimer's disease: Role of inflammation
-
Paris D, Humphrey J, Quadros A, Patel N, Crescentini R, Crawford F, Mullan M. Vasoactive effects of A beta in isolated human cerebrovessels and in a transgenic mouse model of Alzheimer's disease: role of inflammation. Neurol Res. 2003 25 : 642 51.
-
(2003)
Neurol Res.
, vol.25
, pp. 642-51
-
-
Paris, D.1
Humphrey, J.2
Quadros, A.3
Patel, N.4
Crescentini, R.5
Crawford, F.6
Mullan, M.7
-
66
-
-
0035341254
-
Mitochondrial abnormalities in Alzheimer's disease
-
Hirai K, Aliev G, Nunomura A, Fujioka H, Russell RL, Atwood CS, Johnson AB, Kress Y, Vinters HV, Tabaton M, Shimohama S, Cash AD, Siedlak SL, Harris PL, Jones PK, Petersen RB, Perry G, Smith MA. Mitochondrial abnormalities in Alzheimer's disease. J Neurosci. 2001 21 : 3017 23.
-
(2001)
J Neurosci.
, vol.21
, pp. 3017-23
-
-
Hirai, K.1
Aliev, G.2
Nunomura, A.3
Fujioka, H.4
Russell, R.L.5
Atwood, C.S.6
Johnson, A.B.7
Kress, Y.8
Vinters, H.V.9
Tabaton, M.10
Shimohama, S.11
Cash, A.D.12
Siedlak, S.L.13
Harris, P.L.14
Jones, P.K.15
Petersen, R.B.16
Perry, G.17
Smith, M.A.18
-
67
-
-
0034923434
-
Oxidative damage is the earliest event in Alzheimer disease
-
Nunomura A, Perry G, Aliev G, Hirai K, Takeda A, Balraj EK, Jones PK, Ghanbari H, Wataya T, Shimohama S, Chiba S, Atwood CS, Petersen RB, Smith MA. Oxidative damage is the earliest event in Alzheimer disease. J Neuropathol Exp Neurol. 2001 60 : 759 67.
-
(2001)
J Neuropathol Exp Neurol.
, vol.60
, pp. 759-67
-
-
Nunomura, A.1
Perry, G.2
Aliev, G.3
Hirai, K.4
Takeda, A.5
Balraj, E.K.6
Jones, P.K.7
Ghanbari, H.8
Wataya, T.9
Shimohama, S.10
Chiba, S.11
Atwood, C.S.12
Petersen, R.B.13
Smith, M.A.14
-
68
-
-
34547756449
-
Alpha-and beta-secretase activity as a function of age and beta-amyloid in Down syndrome and normal brain
-
Nistor M, Don M, Parekh M, Sarsoza F, Goodus M, Lopez GE, Kawas C, Leverenz J, Doran E, Lott IT, Hill M, Head E. Alpha-and beta-secretase activity as a function of age and beta-amyloid in Down syndrome and normal brain. Neurobiol Aging. 2007 28 : 1493 506.
-
(2007)
Neurobiol Aging.
, vol.28
, pp. 1493-506
-
-
Nistor, M.1
Don, M.2
Parekh, M.3
Sarsoza, F.4
Goodus, M.5
Lopez, G.E.6
Kawas, C.7
Leverenz, J.8
Doran, E.9
Lott, I.T.10
Hill, M.11
Head, E.12
-
69
-
-
15444340119
-
The G protein-coupled receptor kinase 2 is a micro-tubule-associated protein kinase that phosphorylates tubulin
-
Pitcher JA, Hall RA, Daaka Y, Zhang J, Ferguson SS, Hester S, Miller S, Caron MG, Lefkowitz RJ, Barak LS. The G protein-coupled receptor kinase 2 is a micro-tubule-associated protein kinase that phosphorylates tubulin. J Biol Chem. 1998 273 : 12316 24.
-
(1998)
J Biol Chem.
, vol.273
, pp. 12316-24
-
-
Pitcher, J.A.1
Hall, R.A.2
Daaka, Y.3
Zhang, J.4
Ferguson, S.S.5
Hester, S.6
Miller, S.7
Caron, M.G.8
Lefkowitz, R.J.9
Barak, L.S.10
-
70
-
-
0037349646
-
Identification of sites of phosphorylation by G-protein-coupled receptor kinase 2 in beta-tubulin
-
Yoshida N, Haga K, Haga T. Identification of sites of phosphorylation by G-protein-coupled receptor kinase 2 in beta-tubulin. Eur J Biochem. 2003 270 : 1154 63.
-
(2003)
Eur J Biochem.
, vol.270
, pp. 1154-63
-
-
Yoshida, N.1
Haga, K.2
Haga, T.3
-
71
-
-
0032528248
-
GTP-binding-protein-coupled receptor kinase 2 (GRK2) binds and phosphorylates tubulin
-
Haga K, Ogawa H, Haga T, Murofushi H. GTP-binding-protein-coupled receptor kinase 2 (GRK2) binds and phosphorylates tubulin. Eur J Biochem. 1998 255 : 363 8.
-
(1998)
Eur J Biochem.
, vol.255
, pp. 363-8
-
-
Haga, K.1
Ogawa, H.2
Haga, T.3
Murofushi, H.4
-
72
-
-
0033669923
-
The G-protein-coupled receptor kinase GRK4 mediates homologous desensitization of metabotropic gluta-mate receptor 1
-
Sallese M, Salvatore L, D'Urbano E, Sala G, Storto M, Launey T, Nicoletti F, Knopfel T, De Blasi A. The G-protein-coupled receptor kinase GRK4 mediates homologous desensitization of metabotropic gluta-mate receptor 1. FASEB J. 2000 14 : 2569 80.
-
(2000)
FASEB J.
, vol.14
, pp. 2569-80
-
-
Sallese, M.1
Salvatore, L.2
D'Urbano, E.3
Sala, G.4
Storto, M.5
Launey, T.6
Nicoletti, F.7
Knopfel, T.8
De Blasi, A.9
-
73
-
-
0345307648
-
Modulation of metabotropic glutamate receptors as potential treatment for acute and chronic neurodegenerative disorders
-
Lea PMt, Faden AI. Modulation of metabotropic glutamate receptors as potential treatment for acute and chronic neurodegenerative disorders. Drug News Perspect. 2003 16 : 513 22.
-
(2003)
Drug News Perspect.
, vol.16
, pp. 513-22
-
-
Pmt, L.1
Faden, A.I.2
-
74
-
-
15844386027
-
The role of group i metabotropic glutamate receptors in neuronal excitotoxicity in Alzheimer's disease
-
Tsai VW, Scott HL, Lewis RJ, Dodd PR. The role of group I metabotropic glutamate receptors in neuronal excitotoxicity in Alzheimer's disease. Neurotox Res. 2005 7 : 125 41.
-
(2005)
Neurotox Res.
, vol.7
, pp. 125-41
-
-
Tsai, V.W.1
Scott, H.L.2
Lewis, R.J.3
Dodd, P.R.4
-
75
-
-
49949085152
-
Role of metabotropic glutamate receptors in the control of neuroendocrine function
-
Durand D, Pampillo M, Caruso C, Lasaga M. Role of metabotropic glutamate receptors in the control of neuroendocrine function. Neuropharmacology. 2008 55 : 577 83.
-
(2008)
Neuropharmacology.
, vol.55
, pp. 577-83
-
-
Durand, D.1
Pampillo, M.2
Caruso, C.3
Lasaga, M.4
|