High-fat feeding increases insulin receptor and IRS-1 coimmunoprecipitation with SOCS-3, IKKα/β phosphorylation and decreases PI-3 kinase activity in muscle

American Journal of Physiology - Regulatory Integrative and Comparative Physiology

Volumn 296, Issue 6, 2009, Pages

  Yaspelkis III, Ben B ^a   Kvasha, Ilya A ^a   Figueroa, Tania Y ^a  

^a CALIFORNIA STATE UNIVERSITY   (United States)

Author keywords

Insulin resistance; Insulin signaling; Proinflammatory signaling

Indexed keywords

I KAPPA B KINASE ALPHA; I KAPPA B KINASE BETA; INSULIN; INSULIN RECEPTOR; INSULIN RECEPTOR SUBSTRATE 1; PHOSPHATIDYLINOSITOL 3 KINASE; SERINE; SUPPRESSOR OF CYTOKINE SIGNALING 3; TYROSINE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROL GROUP; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; IMMUNOPRECIPITATION; LIMB PERFUSION; LIPID DIET; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RAT; SKELETAL MUSCLE; SPRAGUE DAWLEY RAT;

1-PHOSPHATIDYLINOSITOL 3-KINASE; 3-O-METHYLGLUCOSE; ANIMALS; DIETARY FATS; HINDLIMB; I-KAPPA B KINASE; IMMUNOPRECIPITATION; INFLAMMATION MEDIATORS; INSULIN; INSULIN RECEPTOR SUBSTRATE PROTEINS; INSULIN RESISTANCE; MALE; MUSCLE, SKELETAL; PHOSPHORYLATION; PROTEIN BINDING; RATS; RATS, SPRAGUE-DAWLEY; RECEPTOR, INSULIN; SIGNAL TRANSDUCTION; SUPPRESSOR OF CYTOKINE SIGNALING PROTEINS;

EID: 67049132971     PISSN: 03636119     EISSN: 15221490     Source Type: Journal    
DOI: 10.1152/ajpregu.00117.2009     Document Type: Article

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