-
1
-
-
0033401924
-
Novel targets for CNS gene therapy
-
Federoff HJ. Novel targets for CNS gene therapy. Gene Ther 1999;6(12):1907-1908
-
(1999)
Gene Ther
, vol.6
, Issue.12
, pp. 1907-1908
-
-
Federoff, H.J.1
-
2
-
-
0036007257
-
Why is the global CNS pharmaceutical market so under-penetrated?
-
Pardridge WM. Why is the global CNS pharmaceutical market so under-penetrated? Drug Discov Today 2002;7(1):5-7
-
(2002)
Drug Discov Today
, vol.7
, Issue.1
, pp. 5-7
-
-
Pardridge, W.M.1
-
3
-
-
33646673555
-
A review of nanocarrier-based CNS delivery systems
-
Tiwari SB, Amiji MM. A review of nanocarrier-based CNS delivery systems. Curr Drug Deliv 2006;3(2):219-232
-
(2006)
Curr Drug Deliv
, vol.3
, Issue.2
, pp. 219-232
-
-
Tiwari, S.B.1
Amiji, M.M.2
-
4
-
-
2342635267
-
Neuroprotection in a rat Parkinson model by GDNF gene therapy using EIAV vector
-
Azzouz M, Ralph S, Wong LF, et al. Neuroprotection in a rat Parkinson model by GDNF gene therapy using EIAV vector. Neuroreport 2004;15(6):985-990
-
(2004)
Neuroreport
, vol.15
, Issue.6
, pp. 985-990
-
-
Azzouz, M.1
Ralph, S.2
Wong, L.F.3
-
5
-
-
0035292828
-
Delivery of peptides and proteins through the blood-brain barrier
-
Bickel U, Yoshikawa T, Pardridge WM. Delivery of peptides and proteins through the blood-brain barrier. Adv Drug Deliv Rev 2001;46(1-3):247-279
-
(2001)
Adv Drug Deliv Rev
, vol.46
, Issue.1-3
, pp. 247-279
-
-
Bickel, U.1
Yoshikawa, T.2
Pardridge, W.M.3
-
6
-
-
33746932893
-
Gene delivery to the spinal cord: Comparison between lentiviral, adenoviral, and retroviral vector delivery systems
-
Abdellatif AA, Pelt JL, Benton RL, et al. Gene delivery to the spinal cord: comparison between lentiviral, adenoviral, and retroviral vector delivery systems. J Neurosci Res 2006;84(3):553-567
-
(2006)
J Neurosci Res
, vol.84
, Issue.3
, pp. 553-567
-
-
Abdellatif, A.A.1
Pelt, J.L.2
Benton, R.L.3
-
7
-
-
0034884096
-
Gene therapy for central nervous system repair
-
Berry M, Barrett L, Seymour L, et al. Gene therapy for central nervous system repair. Curr Opin Mol Ther 2001;3(4):338-349
-
(2001)
Curr Opin Mol Ther
, vol.3
, Issue.4
, pp. 338-349
-
-
Berry, M.1
Barrett, L.2
Seymour, L.3
-
8
-
-
0033968031
-
Gene therapy in the CNS
-
Costantini LC, Bakowska JC, Breakefield XO, Isacson O. Gene therapy in the CNS. Gene Ther 2000;7(2):93-109
-
(2000)
Gene Ther
, vol.7
, Issue.2
, pp. 93-109
-
-
Costantini, L.C.1
Bakowska, J.C.2
Breakefield, X.O.3
Isacson, O.4
-
10
-
-
1842353062
-
Gene therapy for disorders of the CNS
-
Friedmann T. Gene therapy for disorders of the CNS. Gene Ther 1994;1(Suppl 1):S47-8
-
(1994)
Gene Ther
, vol.1
, Issue.SUPPL. 1
-
-
Friedmann, T.1
-
11
-
-
0037077040
-
Toxic proteins in neurodegenerative disease
-
Taylor JP, Hardy J, Fischbeck KH. Toxic proteins in neurodegenerative disease. Science 2002;296:1991-1995
-
(2002)
Science
, vol.296
, pp. 1991-1995
-
-
Taylor, J.P.1
Hardy, J.2
Fischbeck, K.H.3
-
12
-
-
23944444806
-
Molecular, structural, and functional characterization of alzheimer's disease: Evidence for a relationship between default activity, amyloid, and memory
-
Buckner RL, Snyder AZ, Shannon BJ, et al. Molecular, structural, and functional characterization of alzheimer's disease: evidence for a relationship between default activity, amyloid, and memory. J Neurosci 2005;25:7709-7717
-
(2005)
J Neurosci
, vol.25
, pp. 7709-7717
-
-
Buckner, R.L.1
Snyder, A.Z.2
Shannon, B.J.3
-
13
-
-
25844469583
-
Drug metabolism and pharmacokinetics, the blood-brain barrier, and central nervous system drug discovery
-
Alavijeh MS, Chishty M, Qaiser MZ, Palmer AM. Drug metabolism and pharmacokinetics, the blood-brain barrier, and central nervous system drug discovery. NeuroRx 2005;2(4):554-571
-
(2005)
NeuroRx
, vol.2
, Issue.4
, pp. 554-571
-
-
Alavijeh, M.S.1
Chishty, M.2
Qaiser, M.Z.3
Palmer, A.M.4
-
14
-
-
0042023711
-
Alzheimer disease in the US population: Prevalence estimates using the 2000 census
-
Hebert LE, Scherr PA, Bienias JL, et al. Alzheimer disease in the US population: prevalence estimates using the 2000 census. Arch Neurol 2003;60:1119-1122
-
(2003)
Arch Neurol
, vol.60
, pp. 1119-1122
-
-
Hebert, L.E.1
Scherr, P.A.2
Bienias, J.L.3
-
15
-
-
34247876141
-
Therapies for Alzheimer's disease
-
Melnikova I. Therapies for Alzheimer's disease. Nat Rev Drug Discov 2007;6(5):341-342
-
(2007)
Nat Rev Drug Discov
, vol.6
, Issue.5
, pp. 341-342
-
-
Melnikova, I.1
-
16
-
-
33749618085
-
Effectiveness of atypical antipsychotic drugs in patients with Alzheimer's disease
-
Schneider LS, Tariot PN, Dagerman KS, et al. Effectiveness of atypical antipsychotic drugs in patients with Alzheimer's disease. N Engl J Med 2006;355(15):1525-1538
-
(2006)
N Engl J Med
, vol.355
, Issue.15
, pp. 1525-1538
-
-
Schneider, L.S.1
Tariot, P.N.2
Dagerman, K.S.3
-
17
-
-
0035503597
-
The curry spice curcumin reduces oxidative damage and amyloid pathology in an Alzheimer transgenic mouse
-
Lim G. The curry spice curcumin reduces oxidative damage and amyloid pathology in an Alzheimer transgenic mouse. J Neurosci 2001;21(21):8370-8377
-
(2001)
J Neurosci
, vol.21
, Issue.21
, pp. 8370-8377
-
-
Lim, G.1
-
18
-
-
16244416174
-
A diet enriched with the omega-3 fatty acid docosahexaenoic acid reduces amyloid burden in an aged Alzheimer mouse model
-
Lim GP, Calon F, Morihara T, et al. A diet enriched with the omega-3 fatty acid docosahexaenoic acid reduces amyloid burden in an aged Alzheimer mouse model. J Neurosci 2005;25:3032-3040
-
(2005)
J Neurosci
, vol.25
, pp. 3032-3040
-
-
Lim, G.P.1
Calon, F.2
Morihara, T.3
-
19
-
-
38549178015
-
Rapid cognitive improvement in Alzheimer's disease following perispinal etanercept administration
-
This paper shows that etanercept has potential, if an acceptable delivery strategy can be employed
-
Tobinick E, Gross H. Rapid cognitive improvement in Alzheimer's disease following perispinal etanercept administration. J Neuroinflamm 2008;5(1):2 • This paper shows that etanercept has potential, if an acceptable delivery strategy can be employed.
-
(2008)
J Neuroinflamm
, vol.5
, Issue.1
, pp. 2
-
-
Tobinick, E.1
Gross, H.2
-
20
-
-
0037654372
-
Growth-factor gene therapy for neurodegenerative disorders
-
Tuszynski MH. Growth-factor gene therapy for neurodegenerative disorders. Lancet Neurology 2002;1(1):51-57
-
(2002)
Lancet Neurology
, vol.1
, Issue.1
, pp. 51-57
-
-
Tuszynski, M.H.1
-
21
-
-
21044458854
-
A phase 1 clinical trial of nerve growth factor gene therapy for Alzheimer disease
-
Tuszynski MH, Thal L, Pay M, et al. A phase 1 clinical trial of nerve growth factor gene therapy for Alzheimer disease. Nat Med 2005;11(5):551-555
-
(2005)
Nat Med
, vol.11
, Issue.5
, pp. 551-555
-
-
Tuszynski, M.H.1
Thal, L.2
Pay, M.3
-
22
-
-
50949166667
-
Mixed results for disease-modification strategies for Alzheimer's disease
-
Opar A. Mixed results for disease-modification strategies for Alzheimer's disease. Nat Rev Drug Discov 2008;7(9):717-718
-
(2008)
Nat Rev Drug Discov
, vol.7
, Issue.9
, pp. 717-718
-
-
Opar, A.1
-
23
-
-
41349111452
-
Parkinson's disease - Part 1: Pathophysiology, symptoms, burden, diagnosis, and assessment
-
Weintraub D, Comella CL, Horn S. Parkinson's disease - Part 1: Pathophysiology, symptoms, burden, diagnosis, and assessment. Am J Manag Care 2008;14:S40-8
-
(2008)
Am J Manag Care
, vol.14
-
-
Weintraub, D.1
Comella, C.L.2
Horn, S.3
-
24
-
-
41349112934
-
Parkinson's disease - Part 2: Treatment of motor symptoms
-
Weintraub D, Comella CL, Horn S. Parkinson's disease - Part 2: Treatment of motor symptoms. Am J Manag Care 2008;14:S49-58
-
(2008)
Am J Manag Care
, vol.14
-
-
Weintraub, D.1
Comella, C.L.2
Horn, S.3
-
25
-
-
0034721690
-
Neurodegeneration prevented by lentiviral vector delivery of GDNF in primate models of Parkinson's disease
-
Kordower JH, Emborg ME, Bloch J, et al. Neurodegeneration prevented by lentiviral vector delivery of GDNF in primate models of Parkinson's disease. Science 2000;290(5492):767-773
-
(2000)
Science
, vol.290
, Issue.5492
, pp. 767-773
-
-
Kordower, J.H.1
Emborg, M.E.2
Bloch, J.3
-
26
-
-
33645159024
-
RNA knockdown as a potential therapeutic strategy in Parkinson's disease
-
Manfredsson FP, Lewin AS, Mandel RJ. RNA knockdown as a potential therapeutic strategy in Parkinson's disease. Gene Ther 2005;13(6):517-524
-
(2005)
Gene Ther
, vol.13
, Issue.6
, pp. 517-524
-
-
Manfredsson, F.P.1
Lewin, A.S.2
Mandel, R.J.3
-
27
-
-
33846225133
-
Huntington's disease
-
Walker FO. Huntington's disease. Lancet 2007;369:218-228
-
(2007)
Lancet
, vol.369
, pp. 218-228
-
-
Walker, F.O.1
-
28
-
-
44449131447
-
Huntington's disease: From pathology and genetics to potential therapies
-
Imarisio S, Carmichael J, Korolchuk V, et al. Huntington's disease: from pathology and genetics to potential therapies. Biochem J 2008;412:191-209
-
(2008)
Biochem J
, vol.412
, pp. 191-209
-
-
Imarisio, S.1
Carmichael, J.2
Korolchuk, V.3
-
29
-
-
41249096422
-
Symptomatic treatment of Huntington Disease
-
Adam OR, Jankovic J. Symptomatic treatment of Huntington Disease. Neurotherapeutics 2008;5:181-197
-
(2008)
Neurotherapeutics
, vol.5
, pp. 181-197
-
-
Adam, O.R.1
Jankovic, J.2
-
30
-
-
33645104092
-
RAAV-mediated shRNA ameliorated neuropathology in Huntington disease model mouse
-
Machida Y, Okada T, Kurosawa M, et al. rAAV-mediated shRNA ameliorated neuropathology in Huntington disease model mouse. Biochem Biophys Res Commun 2006;343(1):190-197
-
(2006)
Biochem Biophys Res Commun
, vol.343
, Issue.1
, pp. 190-197
-
-
Machida, Y.1
Okada, T.2
Kurosawa, M.3
-
31
-
-
12344273726
-
The blood-brain barrier: Bottleneck in brain drug development
-
Pardridge WM. The blood-brain barrier: bottleneck in brain drug development. NeuroRx 2005;2:3-14
-
(2005)
NeuroRx
, vol.2
, pp. 3-14
-
-
Pardridge, W.M.1
-
33
-
-
22944483792
-
The blood-brain barrier/neurovascular unit in health and disease
-
Hawkins BT, Davis TP. The blood-brain barrier/neurovascular unit in health and disease. Pharmacol Rev 2005;57(2):173-185
-
(2005)
Pharmacol Rev
, vol.57
, Issue.2
, pp. 173-185
-
-
Hawkins, B.T.1
Davis, T.P.2
-
34
-
-
0014109002
-
Fine structural localization of a blood-brain barrier to exogenous peroxidase
-
Reese TS, Karnovsky MJ. Fine structural localization of a blood-brain barrier to exogenous peroxidase. J Cell Biol 1967;34(1):207-217
-
(1967)
J Cell Biol
, vol.34
, Issue.1
, pp. 207-217
-
-
Reese, T.S.1
Karnovsky, M.J.2
-
35
-
-
29244463365
-
Astrocyte-endothelial interactions at the blood-brain barrier
-
Abbott NJ, Ronnback L, Hansson E. Astrocyte-endothelial interactions at the blood-brain barrier. Nat Rev Neurosci 2006;7:41-53
-
(2006)
Nat Rev Neurosci
, vol.7
, pp. 41-53
-
-
Abbott, N.J.1
Ronnback, L.2
Hansson, E.3
-
36
-
-
38149090292
-
The blood-brain barrier in health and chronic neurodegenerative disorders
-
This paper provides an excellent review of the BBB with regards to neurodegeneration
-
Zlokovic B. The blood-brain barrier in health and chronic neurodegenerative disorders. Neuron 2008;57(2):178-201 • This paper provides an excellent review of the BBB with regards to neurodegeneration.
-
(2008)
Neuron
, vol.57
, Issue.2
, pp. 178-201
-
-
Zlokovic, B.1
-
37
-
-
0023909760
-
A new aspect of the protective functions of the blood-brain barrier: Activities of four drug-metabolizing enzymes in isolated rat brain microvessels
-
Ghersi-Egea JF, Minn A, Siest G. A new aspect of the protective functions of the blood-brain barrier: activities of four drug-metabolizing enzymes in isolated rat brain microvessels. Life Sci 1988;42(24):2515-2523
-
(1988)
Life Sci
, vol.42
, Issue.24
, pp. 2515-2523
-
-
Ghersi-Egea, J.F.1
Minn, A.2
Siest, G.3
-
38
-
-
0025804884
-
Drug metabolizing enzymes in the brain and cerebral microvessels
-
Minn A, Ghersi-Egea JF, Perrin R, et al. Drug metabolizing enzymes in the brain and cerebral microvessels. Brain Res Rev 1991;16(1):65-82
-
(1991)
Brain Res Rev
, vol.16
, Issue.1
, pp. 65-82
-
-
Minn, A.1
Ghersi-Egea, J.F.2
Perrin, R.3
-
39
-
-
0037079071
-
And gene delivery to the brain: The vascular route
-
This paper provides a concise overview of the pathways for drug delivery to the CNS from blood
-
Pardridge WM. Drug and gene delivery to the brain: the vascular route. Neuron 2002;36:555-558 • This paper provides a concise overview of the pathways for drug delivery to the CNS from blood.
-
(2002)
Neuron
, vol.36
, pp. 555-558
-
-
Drug, P.W.M.1
-
40
-
-
0026695276
-
Recent developments in peptide drug delivery to the brain
-
Pardridge WM. Recent developments in peptide drug delivery to the brain. Pharmacol Toxicol 1992;71(1):3-10
-
(1992)
Pharmacol Toxicol
, vol.71
, Issue.1
, pp. 3-10
-
-
Pardridge, W.M.1
-
41
-
-
0029555077
-
Distribution of 1,3-bis(2-chloroethyl)-1-nitrosourea and tracers in the rabbit brain after interstitial delivery by biodegradable polymer implants
-
Strasser JF, Fung LK, Eller S, et al. Distribution of 1,3-bis(2-chloroethyl)-1-nitrosourea and tracers in the rabbit brain after interstitial delivery by biodegradable polymer implants. J Pharmacol Exp Ther 1995;275(3):1647-1655
-
(1995)
J Pharmacol Exp Ther
, vol.275
, Issue.3
, pp. 1647-1655
-
-
Strasser, J.F.1
Fung, L.K.2
Eller, S.3
-
42
-
-
0036251428
-
Polymer delivery of camptothecin against 9L gliosarcoma: Release, distribution, and efficacy
-
Storm PB, Moriarity JL, Tyler B, et al. Polymer delivery of camptothecin against 9L gliosarcoma: release, distribution, and efficacy. J Neurooncol 2002;56(3):209-217
-
(2002)
J Neurooncol
, vol.56
, Issue.3
, pp. 209-217
-
-
Storm, P.B.1
Moriarity, J.L.2
Tyler, B.3
-
43
-
-
0030583639
-
Alleviation of behavioral deficits in aged rodents following implantation of encapsulated GDNF-producing fibroblasts
-
Ernerich DF, Plone M, Francis J, et al. Alleviation of behavioral deficits in aged rodents following implantation of encapsulated GDNF-producing fibroblasts. Brain Res 1996;736(1-2):99-110
-
(1996)
Brain Res
, vol.736
, Issue.1-2
, pp. 99-110
-
-
Ernerich, D.F.1
Plone, M.2
Francis, J.3
-
44
-
-
33644833272
-
Randomized controlled trial of intraputamenal glial cell line-derived neurotrophic factor infusion in Parkinson disease
-
Lang AE, Gill S, Patel NK, et al. Randomized controlled trial of intraputamenal glial cell line-derived neurotrophic factor infusion in Parkinson disease. Ann Neurol 2006;59(3):459
-
(2006)
Ann Neurol
, vol.59
, Issue.3
, pp. 459
-
-
Lang, A.E.1
Gill, S.2
Patel, N.K.3
-
45
-
-
37549031788
-
Six-month continuous intraputamenal infusion toxicity study of recombinant methionyl human glial cell line-derived neurotrophic factor (r-metHuGDNF) in Rhesus monkeys
-
Hovland DN, Boyd RB, Butt MT, et al. Six-month continuous intraputamenal infusion toxicity study of recombinant methionyl human glial cell line-derived neurotrophic factor (r-metHuGDNF) in Rhesus monkeys. Toxicol Pathol 2007;35(5):676
-
(2007)
Toxicol Pathol
, vol.35
, Issue.5
, pp. 676
-
-
Hovland, D.N.1
Boyd, R.B.2
Butt, M.T.3
-
46
-
-
5644295321
-
Neuroprotective gene therapy for Huntington's disease, using polymer-encapsulated cells engineered to secrete human ciliary neurotrophic factor: Results of a phase I study
-
Bloch J, Bachoud-Levi AC, Deglon N, et al. Neuroprotective gene therapy for Huntington's disease, using polymer-encapsulated cells engineered to secrete human ciliary neurotrophic factor: results of a phase I study. Hum Gene Ther 2004;15(10):968-975
-
(2004)
Hum Gene Ther
, vol.15
, Issue.10
, pp. 968-975
-
-
Bloch, J.1
Bachoud-Levi, A.C.2
Deglon, N.3
-
47
-
-
10544254259
-
Quantification and pharmacokinetics of blood-brain barrier disruption in humans
-
Zünkeler B, Carson RE, Olson J, et al. Quantification and pharmacokinetics of blood-brain barrier disruption in humans. J Neurosurg 1996;85(6):1056-1065
-
(1996)
J Neurosurg
, vol.85
, Issue.6
, pp. 1056-1065
-
-
Zünkeler, B.1
Carson, R.E.2
Olson, J.3
-
48
-
-
0033950424
-
The blood-brain barrier and bilirubin encephalopathy
-
Wennberg R. The blood-brain barrier and bilirubin encephalopathy. Cell Mol Neurobiol 2000;20(1):97-109
-
(2000)
Cell Mol Neurobiol
, vol.20
, Issue.1
, pp. 97-109
-
-
Wennberg, R.1
-
49
-
-
0015320687
-
Ethanol enhancement of blood-brain barrier permeability to catecholamines in chicks
-
Hanig JP, Morrison JM Jr, Krop S. Ethanol enhancement of blood-brain barrier permeability to catecholamines in chicks. Eur J Pharmacol 1972;18(1):79-82
-
(1972)
Eur J Pharmacol
, vol.18
, Issue.1
, pp. 79-82
-
-
Hanig, J.P.1
Morrison Jr., J.M.2
Krop, S.3
-
50
-
-
0020478136
-
Morphologic effect of dimethyl sulfoxide on the blood-brain barrier
-
Broadwell RD, Salcman M, Kaplan RS. Morphologic effect of dimethyl sulfoxide on the blood-brain barrier. Science 1982;217(4555):164-166
-
(1982)
Science
, vol.217
, Issue.4555
, pp. 164-166
-
-
Broadwell, R.D.1
Salcman, M.2
Kaplan, R.S.3
-
51
-
-
0029079452
-
Reversal of multidrug resistance phenotype by surfactants: Relationship to membrane lipid fluidity
-
Dudeja PK, Anderson KM, Harris JS, et al. Reversal of multidrug resistance phenotype by surfactants: relationship to membrane lipid fluidity. Arch Biochem Biophys 1995;319(1):309-315
-
(1995)
Arch Biochem Biophys
, vol.319
, Issue.1
, pp. 309-315
-
-
Dudeja, P.K.1
Anderson, K.M.2
Harris, J.S.3
-
52
-
-
0037607657
-
The role of surfactants in the reversal of active transport mediated by multidrug resistance proteins
-
This article describes a major factor in some of the early successes of nanoparticle use in CNS delivery due to the surfactant interaction with efflux transporters
-
Bogman K, Erne-Brand F, Alsenz J, Drewe J. The role of surfactants in the reversal of active transport mediated by multidrug resistance proteins. J Pharm Sci 2003;92(6):1250-1261 • This article describes a major factor in some of the early successes of nanoparticle use in CNS delivery due to the surfactant interaction with efflux transporters.
-
(2003)
J Pharm Sci
, vol.92
, Issue.6
, pp. 1250-1261
-
-
Bogman, K.1
Erne-Brand, F.2
Alsenz, J.3
Drewe, J.4
-
53
-
-
0033536163
-
Immunization with amyloid-β attenuates Alzheimer's disease-like pathology in the PDAPP mouse
-
Schenk D, Barbour R, Dunn W, et al. Immunization with amyloid-β attenuates Alzheimer's disease-like pathology in the PDAPP mouse. Nature 1999;400(6740):173-177
-
(1999)
Nature
, vol.400
, Issue.6740
, pp. 173-177
-
-
Schenk, D.1
Barbour, R.2
Dunn, W.3
-
54
-
-
48249140247
-
Ultrasound enhanced delivery of molecular imaging and therapeutic agents in Alzheimer's disease mouse models
-
Raymond SB, Treat LH, Dewey JD, et al. Ultrasound enhanced delivery of molecular imaging and therapeutic agents in Alzheimer's disease mouse models. PLoS ONE 2008;3(5):e2175
-
(2008)
PLoS ONE
, vol.3
, Issue.5
-
-
Raymond, S.B.1
Treat, L.H.2
Dewey, J.D.3
-
55
-
-
1042265187
-
Neuropathology and pathogenesis of encephalitis following amyloid β Immunization in Alzheimer's disease
-
Ferrer I, Rovira MB, Guerra MLS, et al. Neuropathology and pathogenesis of encephalitis following amyloid β Immunization in Alzheimer's disease. Brain Pathol 2004;14(1):11-20
-
(2004)
Brain Pathol
, vol.14
, Issue.1
, pp. 11-20
-
-
Ferrer, I.1
Rovira, M.B.2
Guerra, M.L.S.3
-
56
-
-
84872213231
-
-
cited; Available from
-
NCBI. PubChem Compound. cited; Available from: http://pubchem.ncbi.nlm. nih.gov/
-
PubChem Compound
-
-
-
57
-
-
33845888453
-
Treatment of central nervous system degenerative disorders. Eleventh editon
-
Brunton LL, editor, New York: McGraw-Hill
-
Standaert DG, Young AB. Treatment of central nervous system degenerative disorders. Eleventh editon. In: Brunton LL, editor, Goodman and Gillman's Pharmacologic basis of therapeutics. New York: McGraw-Hill; 2006. p. 527-545
-
(2006)
Goodman and Gillman's Pharmacologic Basis of Therapeutics
, pp. 527-545
-
-
Standaert, D.G.1
Young, A.B.2
-
58
-
-
0030053701
-
Transport of Dopamine at the blood-brain barrier of the guinea pig: Inhibition by psychotropic drugs and nicotine
-
Martel CL, Mackic JB, Adams JD, et al. Transport of Dopamine at the blood-brain barrier of the guinea pig: inhibition by psychotropic drugs and nicotine. Pharm Res 1996;13(2):290-295
-
(1996)
Pharm Res
, vol.13
, Issue.2
, pp. 290-295
-
-
Martel, C.L.1
Mackic, J.B.2
Adams, J.D.3
-
59
-
-
17344392837
-
The 4F2hc/LAT1 complex transports L-DOPA across the blood-brain barrier
-
Kageyama T, Nakamura M, Matsuo A, et al. The 4F2hc/LAT1 complex transports L-DOPA across the blood-brain barrier. Brain Res 2000;879(1-2):115- 121
-
(2000)
Brain Res
, vol.879
, Issue.1-2
, pp. 115-121
-
-
Kageyama, T.1
Nakamura, M.2
Matsuo, A.3
-
60
-
-
0033526179
-
Carrier-mediated or specialized transport of drugs across the blood-brain barrier
-
Tsuji A, Tamai I. Carrier-mediated or specialized transport of drugs across the blood-brain barrier. Adv Drug Deliv Rev 1999;36(2-3):277-290
-
(1999)
Adv Drug Deliv Rev
, vol.36
, Issue.2-3
, pp. 277-290
-
-
Tsuji, A.1
Tamai, I.2
-
61
-
-
34447114618
-
Transvascular delivery of small interfering RNA to the central nervous system
-
This paper describes a novel delivery strategy for siRNA to the CNS
-
Kumar P, Wu H, McBride JL, et al. Transvascular delivery of small interfering RNA to the central nervous system. Nature 2007;448:39-43 • This paper describes a novel delivery strategy for siRNA to the CNS.
-
(2007)
Nature
, vol.448
, pp. 39-43
-
-
Kumar, P.1
Wu, H.2
McBride, J.L.3
-
62
-
-
33748452503
-
Molecular Trojan horses for blood-brain barrier drug delivery
-
Pardridge WM. Molecular Trojan horses for blood-brain barrier drug delivery. Curr Opin Pharm 2006;6:494-500
-
(2006)
Curr Opin Pharm
, vol.6
, pp. 494-500
-
-
Pardridge, W.M.1
-
63
-
-
0036605677
-
Functional expression and localization of P-glycoprotein at the blood brain barrier
-
Bendayan R, Lee G, Bendayan M. Functional expression and localization of P-glycoprotein at the blood brain barrier. Microsc Res Tech 2002;57(5):365-380
-
(2002)
Microsc Res Tech
, vol.57
, Issue.5
, pp. 365-380
-
-
Bendayan, R.1
Lee, G.2
Bendayan, M.3
-
64
-
-
0033833430
-
Increased drug delivery to the brain by P-glycoprotein inhibition
-
Sadeque AJ, Wandel C, He H, et al. Increased drug delivery to the brain by P-glycoprotein inhibition. Clin Pharm Ther 2000;68:231-237
-
(2000)
Clin Pharm Ther
, vol.68
, pp. 231-237
-
-
Sadeque, A.J.1
Wandel, C.2
He, H.3
-
65
-
-
0026783425
-
A strategy for delivering peptides into the central nervous system by sequential metabolism
-
This article provided one of the foundations for the 'lock-in' strategy to deliver drugs to the CNS
-
Bodor N, Prokai L, Wu WM, et al. A strategy for delivering peptides into the central nervous system by sequential metabolism. Science 1992;257(5077):1698-700 • This article provided one of the foundations for the 'lock-in' strategy to deliver drugs to the CNS.
-
(1992)
Science
, vol.257
, Issue.5077
, pp. 1698-1700
-
-
Bodor, N.1
Prokai, L.2
Wu, W.M.3
-
66
-
-
0035990561
-
Synthesis and biological evaluations of brain-targeted chemical delivery systems of [Nva2]-TRH
-
Wu J, Yoon SH, Wu WM, Bodor N. Synthesis and biological evaluations of brain-targeted chemical delivery systems of [Nva2]-TRH. J Pharm Pharmacol 2002;54(7):945-950
-
(2002)
J Pharm Pharmacol
, vol.54
, Issue.7
, pp. 945-950
-
-
Wu, J.1
Yoon, S.H.2
Wu, W.M.3
Bodor, N.4
-
67
-
-
21344453274
-
Nasal drug administration: Potential for targeted central nervous system delivery
-
Graff CL, Pollack GM. Nasal drug administration: potential for targeted central nervous system delivery. J Pharm Sci 2005;94:1187-1195
-
(2005)
J Pharm Sci
, vol.94
, pp. 1187-1195
-
-
Graff, C.L.1
Pollack, G.M.2
-
69
-
-
0742304311
-
The potential of nasal application for delivery to the central brain - A microdialysis study of fluorescein in rats
-
Bagger MA, Bechgaard E. The potential of nasal application for delivery to the central brain - a microdialysis study of fluorescein in rats. Eur J Pharm Sci 2004;21(2-3):235-242
-
(2004)
Eur J Pharm Sci
, vol.21
, Issue.2-3
, pp. 235-242
-
-
Bagger, M.A.1
Bechgaard, E.2
-
70
-
-
14944384581
-
Intranasal administration of nerve growth factor (NGF) rescues recognition memory deficits in AD11 anti-NGF transgenic mice
-
De Rosa R, Garcia AA, Braschi C, et al. Intranasal administration of nerve growth factor (NGF) rescues recognition memory deficits in AD11 anti-NGF transgenic mice. Proc Natl Acad Sci USA 2005;102(10):3811-3816
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, Issue.10
, pp. 3811-3816
-
-
De Rosa, R.1
Garcia, A.A.2
Braschi, C.3
-
71
-
-
0029959813
-
Bioavailability and bioactivity of three different doses of nasal growth hormone (GH) administered to GH-deficient patients: Comparison with intravenous and subcutaneous administration
-
Laursen T, Grandjean B, Jorgensen JO, Christiansen JS. Bioavailability and bioactivity of three different doses of nasal growth hormone (GH) administered to GH-deficient patients: comparison with intravenous and subcutaneous administration. Eur J Endocrinol 1996;135(3):309-315
-
(1996)
Eur J Endocrinol
, vol.135
, Issue.3
, pp. 309-315
-
-
Laursen, T.1
Grandjean, B.2
Jorgensen, J.O.3
Christiansen, J.S.4
-
72
-
-
0035875455
-
Intranasal administration of insulin-like growth factor-I bypasses the blood-brain barrier and protects against focal cerebral ischemic damage
-
This provided evidence for the transport of larger molecules through the intranasal route
-
Liu XF, Fawcett JR, Thorne RG, et al. Intranasal administration of insulin-like growth factor-I bypasses the blood-brain barrier and protects against focal cerebral ischemic damage. J Neurol Sci 2001;187(1-2):91-97 • This provided evidence for the transport of larger molecules through the intranasal route.
-
(2001)
J Neurol Sci
, vol.187
, Issue.1-2
, pp. 91-97
-
-
Liu, X.F.1
Fawcett, J.R.2
Thorne, R.G.3
-
73
-
-
0035800541
-
Non-invasive intranasal insulin-like growth factor-I reduces infarct volume and improves neurologic function in rats following middle cerebral artery occlusion
-
Liu XF, Fawcett JR, Thorne RG, Frey WH 2nd. Non-invasive intranasal insulin-like growth factor-I reduces infarct volume and improves neurologic function in rats following middle cerebral artery occlusion. Neurosci Lett 2001;308(2):91-94
-
(2001)
Neurosci Lett
, vol.308
, Issue.2
, pp. 91-94
-
-
Liu, X.F.1
Fawcett, J.R.2
Thorne, R.G.3
Frey II, W.H.4
-
74
-
-
16844374013
-
Intranasal drug delivery for brain targeting
-
Vyas TK, Shahiwala A, Marathe S, Misra A. Intranasal drug delivery for brain targeting. Curr Drug Deliv 2005;2(2):165-175
-
(2005)
Curr Drug Deliv
, vol.2
, Issue.2
, pp. 165-175
-
-
Vyas, T.K.1
Shahiwala, A.2
Marathe, S.3
Misra, A.4
-
75
-
-
0037062327
-
Intranasal delivery could be used to administer drugs directly to the brain
-
Lawrence D. Intranasal delivery could be used to administer drugs directly to the brain. Lancet 2002;359(9318):1674
-
(2002)
Lancet
, vol.359
, Issue.9318
, pp. 1674
-
-
Lawrence, D.1
-
76
-
-
33645731771
-
Preliminary brain-targeting studies on intranasal mucoadhesive microemulsions of sumatriptan
-
Vyas TK, Babbar AK, Sharma RK, et al. Preliminary brain-targeting studies on intranasal mucoadhesive microemulsions of sumatriptan. AAPS PharmSciTech 2006;7(1):E8
-
(2006)
AAPS PharmSciTech
, vol.7
, Issue.1
-
-
Vyas, T.K.1
Babbar, A.K.2
Sharma, R.K.3
-
77
-
-
1042269557
-
Is nose-to-brain transport of drugs in man a reality?
-
Illum L. Is nose-to-brain transport of drugs in man a reality? J Pharm Pharmacol 2004;56(1):3-17
-
(2004)
J Pharm Pharmacol
, vol.56
, Issue.1
, pp. 3-17
-
-
Illum, L.1
-
78
-
-
0029844165
-
Effect of chronic treatment with octreotide nasal powder on serum levels of growth hormone, insulin-like growth factor I, insulin-like growth factor binding proteins and 3 in acromegalic patients
-
Invitti C, Fatti L, Camboni MG, et al. Effect of chronic treatment with octreotide nasal powder on serum levels of growth hormone, insulin-like growth factor I, insulin-like growth factor binding proteins and 3 in acromegalic patients. J Endocrinol Invest 1996;19(8):548-555
-
(1996)
J Endocrinol Invest
, vol.19
, Issue.8
, pp. 548-555
-
-
Invitti, C.1
Fatti, L.2
Camboni, M.G.3
-
79
-
-
0034730443
-
Manipulating neuropeptidergic pathways in humans: A novel approach to neuropharmacology?
-
Fehm HL, Perras B, Smolnik R, et al. Manipulating neuropeptidergic pathways in humans: a novel approach to neuropharmacology? Eur J Pharmacol 2000;405(1-3):43-54
-
(2000)
Eur J Pharmacol
, vol.405
, Issue.1-3
, pp. 43-54
-
-
Fehm, H.L.1
Perras, B.2
Smolnik, R.3
-
80
-
-
0037272797
-
An effective absorption behavior of insulin for diabetic treatment following intranasal delivery using porous spherical calcium carbonate in monkeys and healthy human volunteers
-
Haruta S, Hanafusa T, Fukase H, et al. An effective absorption behavior of insulin for diabetic treatment following intranasal delivery using porous spherical calcium carbonate in monkeys and healthy human volunteers. Diabetes Technol Ther 2003;5(1):1-9
-
(2003)
Diabetes Technol Ther
, vol.5
, Issue.1
, pp. 1-9
-
-
Haruta, S.1
Hanafusa, T.2
Fukase, H.3
-
81
-
-
0034083868
-
Activity-dependent neurotrophic factor: Intranasal administration of femtomolar-acting peptides improve performance in a water maze
-
Gozes I, Giladi E, Pinhasov A, et al. Activity-dependent neurotrophic factor: intranasal administration of femtomolar-acting peptides improve performance in a water maze. J Pharmacol Exp Ther 2000;293(3):1091-1098
-
(2000)
J Pharmacol Exp Ther
, vol.293
, Issue.3
, pp. 1091-1098
-
-
Gozes, I.1
Giladi, E.2
Pinhasov, A.3
-
82
-
-
12344302551
-
Intranasal delivery of nerve growth factor to protect the central nervous system against acute cerebral infarction
-
Zhao HM, Liu XF, Mao XW, Chen CF. Intranasal delivery of nerve growth factor to protect the central nervous system against acute cerebral infarction. Chin Med Sci J 2004;19(4):257-261
-
(2004)
Chin Med Sci J
, vol.19
, Issue.4
, pp. 257-261
-
-
Zhao, H.M.1
Liu, X.F.2
Mao, X.W.3
Chen, C.F.4
-
83
-
-
0036330242
-
Labeling of cerebral amyloid beta deposits in vivo using intranasal basic fibroblast growth factor and serum amyloid P component in mice
-
Shi J, Perry G, Berridge MS, et al. Labeling of cerebral amyloid beta deposits in vivo using intranasal basic fibroblast growth factor and serum amyloid P component in mice. J Nucl Med 2002;43(8):1044-1051
-
(2002)
J Nucl Med
, vol.43
, Issue.8
, pp. 1044-1051
-
-
Shi, J.1
Perry, G.2
Berridge, M.S.3
-
84
-
-
34248218097
-
Can nasal drug delivery bypass the blood-brain barrier?
-
This review examined the differences between intranasal delivery in animals and humans. This gives an anatomical basis and experimental data to suggest that intranasal delivery in humans may be more challenging than previously thought
-
Merkus FWHM, van den Berg MP. Can nasal drug delivery bypass the blood-brain barrier? Drugs R D 2007;8(3):133-144 •• This review examined the differences between intranasal delivery in animals and humans. This gives an anatomical basis and experimental data to suggest that intranasal delivery in humans may be more challenging than previously thought
-
(2007)
Drugs R D
, vol.8
, Issue.3
, pp. 133-144
-
-
Fwhm, M.1
Van Den Berg, M.P.2
-
85
-
-
34047157527
-
Formulation and physiological factors influencing CNS delivery upon intranasal administration
-
Vyas TK, Tiwari SB, Amiji MM. Formulation and physiological factors influencing CNS delivery upon intranasal administration. Crit Rev Ther Drug Carrier Syst 2006;23(4):319-347
-
(2006)
Crit Rev Ther Drug Carrier Syst
, vol.23
, Issue.4
, pp. 319-347
-
-
Vyas, T.K.1
Tiwari, S.B.2
Amiji, M.M.3
-
86
-
-
35348970995
-
Role of nanotechnology in pharmaceutical product development
-
Devalapally H, Chakilam A, Amiji MM. Role of nanotechnology in pharmaceutical product development. J Pharm Sci 2007;96(10):2547-2565
-
(2007)
J Pharm Sci
, vol.96
, Issue.10
, pp. 2547-2565
-
-
Devalapally, H.1
Chakilam, A.2
Amiji, M.M.3
-
87
-
-
33646673555
-
A review of nanocarrier-based CNS delivery systems
-
Tiwari SB, Amiji MM. A review of nanocarrier-based CNS delivery systems. Curr Drug Deliv 2006;3:219-232
-
(2006)
Curr Drug Deliv
, vol.3
, pp. 219-232
-
-
Tiwari, S.B.1
Amiji, M.M.2
-
88
-
-
0030447660
-
Brain drug delivery of small molecules using immunoliposomes
-
Huwyler J, Wu D, Pardridge WM. Brain drug delivery of small molecules using immunoliposomes. Proc Natl Acad Sci 1996;93:14164-14169
-
(1996)
Proc Natl Acad Sci
, vol.93
, pp. 14164-14169
-
-
Huwyler, J.1
Wu, D.2
Pardridge, W.M.3
-
89
-
-
0036665418
-
Antisense gene therapy of brain cancer with an artificial virus gene delivery system
-
Zhang Y, Zhu C, Pardridge WM. Antisense gene therapy of brain cancer with an artificial virus gene delivery system. Mol Ther 2002;6(1):67-72
-
(2002)
Mol Ther
, vol.6
, Issue.1
, pp. 67-72
-
-
Zhang, Y.1
Zhu, C.2
Pardridge, W.M.3
-
90
-
-
0036463371
-
Drug and gene targeting to the brain with molecular Trojan horses
-
Pardridge WM. Drug and gene targeting to the brain with molecular Trojan horses. Nat Rev Drug Discov 2002;1(2):131-139
-
(2002)
Nat Rev Drug Discov
, vol.1
, Issue.2
, pp. 131-139
-
-
Pardridge, W.M.1
-
91
-
-
35348900910
-
Emulsion-based delivery systems for lipophilic bioactive components
-
McClements DJ, Decker EA, Weiss J. Emulsion-based delivery systems for lipophilic bioactive components. J Food Sci 2007;72:R109-24
-
(2007)
J Food Sci
, vol.72
-
-
McClements, D.J.1
Decker, E.A.2
Weiss, J.3
-
92
-
-
36549029876
-
Improved oral bioavailability and brain transport of Saquinavir upon administration in novel nanoemulsion formulations
-
Vyas TK, Shahiwala A, Amiji MM. Improved oral bioavailability and brain transport of Saquinavir upon administration in novel nanoemulsion formulations. Int J Pharm 2008;347:93-101
-
(2008)
Int J Pharm
, vol.347
, pp. 93-101
-
-
Vyas, T.K.1
Shahiwala, A.2
Amiji, M.M.3
-
93
-
-
0031692458
-
Astrocytes are mainly responsible for the polyunsaturated fatty acid enrichment in blood-brain barrier endothelial cells in vitro
-
Bernoud N, Fenart L, Benistant C, et al. Astrocytes are mainly responsible for the polyunsaturated fatty acid enrichment in blood-brain barrier endothelial cells in vitro. J Lipid Res 1998;39:1816-1824
-
(1998)
J Lipid Res
, vol.39
, pp. 1816-1824
-
-
Bernoud, N.1
Fenart, L.2
Benistant, C.3
-
94
-
-
0038032150
-
Solid lipid nanoparticles (SLN) for controlled drug delivery - A review of the state of the art
-
Müller RH, Mäder K, Gohla S. Solid lipid nanoparticles (SLN) for controlled drug delivery - a review of the state of the art. Eur J Pharm Biopharm 2000;50(1):161-177
-
(2000)
Eur J Pharm Biopharm
, vol.50
, Issue.1
, pp. 161-177
-
-
Müller, R.H.1
Mäder, K.2
Gohla, S.3
-
95
-
-
0035984818
-
Intravenous administration to rabbits of non-stealth and stealth doxorubicin-loaded solid lipid nanoparticles at increasing concentrations of stealth agent: Pharmacokinetics and distribution of doxorubicin in brain and other tissues
-
Zara GP, Cavalli R, Bargoni A, et al. Intravenous administration to rabbits of non-stealth and stealth doxorubicin-loaded solid lipid nanoparticles at increasing concentrations of stealth agent: pharmacokinetics and distribution of doxorubicin in brain and other tissues. J Drug Target 2002;10(4):327-335
-
(2002)
J Drug Target
, vol.10
, Issue.4
, pp. 327-335
-
-
Zara, G.P.1
Cavalli, R.2
Bargoni, A.3
-
97
-
-
0028911362
-
Passage of peptides through the blood-brain barrier with colloidal polymer particles (nanoparticles)
-
Kreuter J, Alyautdin RN, Kharkevich DA, Ivanov AA. Passage of peptides through the blood-brain barrier with colloidal polymer particles (nanoparticles). Brain Res 1995;674(1):171-174
-
(1995)
Brain Res
, vol.674
, Issue.1
, pp. 171-174
-
-
Kreuter, J.1
Alyautdin, R.N.2
Kharkevich, D.A.3
Ivanov, A.A.4
-
98
-
-
1142309721
-
Specific role of polysorbate 80 coating on the targeting of nanoparticles to the brain
-
Sun W, Xie C, Wang H, Hu Y. Specific role of polysorbate 80 coating on the targeting of nanoparticles to the brain. Biomaterials 2004;25(15):3065-3071
-
(2004)
Biomaterials
, vol.25
, Issue.15
, pp. 3065-3071
-
-
Sun, W.1
Xie, C.2
Wang, H.3
Hu, Y.4
-
99
-
-
12344273726
-
The blood-brain barrier: Bottleneck in brain drug development
-
Pardridge WM. The blood-brain barrier: bottleneck in brain drug development. NeuroRx 2005;2(1):3-14
-
(2005)
NeuroRx
, vol.2
, Issue.1
, pp. 3-14
-
-
Pardridge, W.M.1
-
100
-
-
33846848061
-
Strategies for intranasal delivery of therapeutics for the prevention and treatment of neuroAIDS
-
Hanson LR, Frey WH 2nd. Strategies for intranasal delivery of therapeutics for the prevention and treatment of neuroAIDS. J Neuroimmune Pharmacol 2007;2(1):81-86
-
(2007)
J Neuroimmune Pharmacol
, vol.2
, Issue.1
, pp. 81-86
-
-
Hanson, L.R.1
Frey II, W.H.2
-
101
-
-
0035693963
-
Delivery of neurotrophic factors to the central nervous system: Pharmacokinetic considerations
-
Thorne RG, Frey WH 2nd. Delivery of neurotrophic factors to the central nervous system: pharmacokinetic considerations. Clin Pharmacokinet 2001;40(12):907-946
-
(2001)
Clin Pharmacokinet
, vol.40
, Issue.12
, pp. 907-946
-
-
Thorne, R.G.1
Frey II, W.H.2
-
102
-
-
3242740239
-
Delivery of insulin-like growth factor-I to the rat brain and spinal cord along olfactory and trigeminal pathways following intranasal administration
-
Thorne RG, Pronk GJ, Padmanabhan V, Frey WH 2nd. Delivery of insulin-like growth factor-I to the rat brain and spinal cord along olfactory and trigeminal pathways following intranasal administration. Neuroscience 2004;127(2):481-496
-
(2004)
Neuroscience
, vol.127
, Issue.2
, pp. 481-496
-
-
Thorne, R.G.1
Pronk, G.J.2
Padmanabhan, V.3
Frey II, W.H.4
-
103
-
-
33846572874
-
Projected number of people with Parkinson disease in the most populous nations, 2005 through 2030
-
Dorsey ER, Constantinescu R, Thompson JP, et al. Projected number of people with Parkinson disease in the most populous nations, 2005 through 2030. Neurology 2007;68(5):384-386
-
(2007)
Neurology
, vol.68
, Issue.5
, pp. 384-386
-
-
Dorsey, E.R.1
Constantinescu, R.2
Thompson, J.P.3
-
104
-
-
0029939467
-
Multiple Sclerosis: A coordinated immunological attack against myelin in the central nervous system
-
Steinman MDL. Multiple Sclerosis: a coordinated immunological attack against myelin in the central nervous system. Cell 1996;85(3):299-302
-
(1996)
Cell
, vol.85
, Issue.3
, pp. 299-302
-
-
Steinman, M.D.L.1
-
105
-
-
0033797526
-
Estimation of the amyotrophic lateral sclerosis incidence by capture-recapture method in the Limousin region of France
-
Preux PM, Druet-Cabanac M, Couratier P, et al. Estimation of the amyotrophic lateral sclerosis incidence by capture-recapture method in the Limousin region of France. J Clin Epidemiol 2000;53(10):1025-1029
-
(2000)
J Clin Epidemiol
, vol.53
, Issue.10
, pp. 1025-1029
-
-
Preux, P.M.1
Druet-Cabanac, M.2
Couratier, P.3
-
106
-
-
23644437308
-
Comparison of the capability of GDNF, BDNF, or both, to protect nigrostriatal neurons in a rat model of Parkinson's disease
-
Sun M, Kong L, Wang X, et al. Comparison of the capability of GDNF, BDNF, or both, to protect nigrostriatal neurons in a rat model of Parkinson's disease. Brain Res 2005;1052(2):119-129
-
(2005)
Brain Res
, vol.1052
, Issue.2
, pp. 119-129
-
-
Sun, M.1
Kong, L.2
Wang, X.3
-
107
-
-
0035451329
-
Recombinant proteins for neurodegenerative diseases: The delivery issue
-
Aebischer P, Ridet JL. Recombinant proteins for neurodegenerative diseases: the delivery issue. Trends Neurosci 2001;24(9):533-540
-
(2001)
Trends Neurosci
, vol.24
, Issue.9
, pp. 533-540
-
-
Aebischer, P.1
Ridet, J.L.2
-
108
-
-
0032826920
-
Cellular delivery of trophic factors for the treatment of Huntington's disease: Is neuroprotection possible?
-
Kordower JH, Isacson O, Emerich DF. Cellular delivery of trophic factors for the treatment of Huntington's disease: is neuroprotection possible? Exp Neurol 1999;159:4-20
-
(1999)
Exp Neurol
, vol.159
, pp. 4-20
-
-
Kordower, J.H.1
Isacson, O.2
Emerich, D.F.3
-
109
-
-
0025081990
-
Liposomes as carriers of cisplatin into the central nervous system-experiments with 9L gliomas in rats
-
Tokyo
-
Shibata S, Ochi A, Mori K. Liposomes as carriers of cisplatin into the central nervous system-experiments with 9L gliomas in rats. Neurol Med Chir (Tokyo) 1990;30(4):242-245
-
(1990)
Neurol Med Chir
, vol.30
, Issue.4
, pp. 242-245
-
-
Shibata, S.1
Ochi, A.2
Mori, K.3
-
110
-
-
0344970108
-
Efficient oligonucleotide delivery using the HVJ-liposome method in the central nervous system
-
Yamada K, Moriguchi A, Morishita R, et al. Efficient oligonucleotide delivery using the HVJ-liposome method in the central nervous system. Am J Physiol Regul Integr Comp Physiol 1996;271(5):R1212-20
-
(1996)
Am J Physiol Regul Integr Comp Physiol
, vol.271
, Issue.5
-
-
Yamada, K.1
Moriguchi, A.2
Morishita, R.3
-
111
-
-
23944465946
-
Tf-lipoplex-mediated NGF gene transfer to the CNS: Neuronal protection and recovery in an excitotoxic model of brain injury
-
Teresa Girão da Cruz M, Cardoso ALC, de Almeida LP, et al. Tf-lipoplex-mediated NGF gene transfer to the CNS: neuronal protection and recovery in an excitotoxic model of brain injury. Gene Ther 2005;12(16):1242- 1252
-
(2005)
Gene Ther
, vol.12
, Issue.16
, pp. 1242-1252
-
-
Teresa Girão Da Cruz, M.1
Cardoso, A.L.C.2
De Almeida, L.P.3
-
112
-
-
38449115418
-
Convection-enhanced delivery of nanoliposomal CPT-11 (irinotecan) and PEGylated liposomal doxorubicin (Doxil) in rodent intracranial brain tumor xenografts
-
Krauze MT, Noble CO, Kawaguchi T, et al. Convection-enhanced delivery of nanoliposomal CPT-11 (irinotecan) and PEGylated liposomal doxorubicin (Doxil) in rodent intracranial brain tumor xenografts. Neurooncol 2007;9(4):393-403
-
(2007)
Neurooncol
, vol.9
, Issue.4
, pp. 393-403
-
-
Krauze, M.T.1
Noble, C.O.2
Kawaguchi, T.3
-
113
-
-
4544240398
-
Paclitaxel nanoparticles for the potential treatment of brain tumors
-
Koziara JM, Lockman PR, Allen DD, Mumper RJ. Paclitaxel nanoparticles for the potential treatment of brain tumors. J Control Release 2004;99(2):259-269
-
(2004)
J Control Release
, vol.99
, Issue.2
, pp. 259-269
-
-
Koziara, J.M.1
Lockman, P.R.2
Allen, D.D.3
Mumper, R.J.4
-
114
-
-
33646648428
-
Etoposide-incorporated tripalmitin nanoparticles with different surface charge: Formulation, characterization, radiolabeling, and biodistribution studies
-
Reddy L, Sharma R, Chuttani K, et al. Etoposide-incorporated tripalmitin nanoparticles with different surface charge: formulation, characterization, radiolabeling, and biodistribution studies. AAPS Journal 2004;6(3):55-64
-
(2004)
AAPS Journal
, vol.6
, Issue.3
, pp. 55-64
-
-
Reddy, L.1
Sharma, R.2
Chuttani, K.3
-
115
-
-
0032950389
-
Body distribution in mice of intravenously injected camptothecin solid lipid nanoparticles and targeting effect on brain
-
Yang SC, Lu LF, Cai Y, et al. Body distribution in mice of intravenously injected camptothecin solid lipid nanoparticles and targeting effect on brain. J Control Release 1999;59(3):299-307
-
(1999)
J Control Release
, vol.59
, Issue.3
, pp. 299-307
-
-
Yang, S.C.1
Lu, L.F.2
Cai, Y.3
-
116
-
-
50849094554
-
TAT-conjugated nanoparticles for the CNS delivery of anti-HIV drugs
-
This shows a strategy for using endogenous transporters to traffic encapsulated drug payload
-
Rao KS, Reddy MK, Horning JL, Labhasetwar V. TAT-conjugated nanoparticles for the CNS delivery of anti-HIV drugs. Biomaterials 2008;29(33):4429-4438 • This shows a strategy for using endogenous transporters to traffic encapsulated drug payload.
-
(2008)
Biomaterials
, vol.29
, Issue.33
, pp. 4429-4438
-
-
Rao, K.S.1
Reddy, M.K.2
Horning, J.L.3
Labhasetwar, V.4
-
117
-
-
33750512963
-
Effect of nanoparticulate polybutylcyanoacrylate and methylmethacrylate- sulfopropylmethacrylate on the permeability of zidovudine and lamivudine across the in vitro blood-brain barrier
-
Kuo YC, Chen HH. Effect of nanoparticulate polybutylcyanoacrylate and methylmethacrylate-sulfopropylmethacrylate on the permeability of zidovudine and lamivudine across the in vitro blood-brain barrier. Int J Pharm 2006;327:160-169
-
(2006)
Int J Pharm
, vol.327
, pp. 160-169
-
-
Kuo, Y.C.1
Chen, H.H.2
-
118
-
-
33645863163
-
Biodistribution of polysorbate 80-coated doxorubicin-loaded [14 C]-poly(butyl cyanoacrylate) nanoparticles after intravenous administration to glioblastoma-bearing rats
-
Ambruosi A, Khalansky AS, Yamamoto H, et al. Biodistribution of polysorbate 80-coated doxorubicin-loaded [14 C]-poly(butyl cyanoacrylate) nanoparticles after intravenous administration to glioblastoma-bearing rats. J Drug Target 2006;14(2):97-105
-
(2006)
J Drug Target
, vol.14
, Issue.2
, pp. 97-105
-
-
Ambruosi, A.1
Khalansky, A.S.2
Yamamoto, H.3
-
119
-
-
34548041658
-
Targeting the central nervous system: In vivo experiments with peptide-derivatized nanoparticles loaded with Loperamide and Rhodamine-123
-
Tosi G, Costantino L, Rivasi F, et al. Targeting the central nervous system: In vivo experiments with peptide-derivatized nanoparticles loaded with Loperamide and Rhodamine-123. J Control Release 2007;122(1):1-9
-
(2007)
J Control Release
, vol.122
, Issue.1
, pp. 1-9
-
-
Tosi, G.1
Costantino, L.2
Rivasi, F.3
-
120
-
-
26944477353
-
Peptide-derivatized biodegradable nanoparticles able to cross the blood-brain barrier
-
Costantino L, Gandolfi F, Tosi G, et al. Peptide-derivatized biodegradable nanoparticles able to cross the blood-brain barrier. J Control Release 2005;108(1):84-96
-
(2005)
J Control Release
, vol.108
, Issue.1
, pp. 84-96
-
-
Costantino, L.1
Gandolfi, F.2
Tosi, G.3
-
121
-
-
33947625559
-
Efficient gene delivery targeted to the brain using a transferrin-conjugated polyethyleneglycol-modified polyamidoamine dendrimer
-
Huang RQ, Qu YH, Ke WL, et al. Efficient gene delivery targeted to the brain using a transferrin-conjugated polyethyleneglycol-modified polyamidoamine dendrimer. FASEB J 2007;21(4):1117-1125
-
(2007)
FASEB J
, vol.21
, Issue.4
, pp. 1117-1125
-
-
Huang, R.Q.1
Qu, Y.H.2
Ke, W.L.3
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