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Feng Y, Mao G, Ren X, et al. Ser1369Ala variant in sulfonylurea receptor gene ABCC8 is associated with antidiabetic efficacy of gliclazide in Chinese type 2 diabetic patients. Diabetes Care 2008; 31:1939-1944. This article demonstrates that Chinese patients homozygous for the Ala/Ala variant of the sulfonylurea receptor have a statistically significant decrease in FPG compared with Ser/Ser homozygotes.
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(2008)
Diabetes Care
, vol.31
, pp. 1939-1944
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Feng, Y.1
Mao, G.2
Ren, X.3
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50
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34547585382
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Variation in TCF7L2 influences therapeutic response to sulfonylureas: A GoDARTs study
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A retrospective study suggesting that diabetic individuals with TCF7L2 variants respond differently to sulfonylureas than to metformin
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Pearson ER, Donnelly LA, Kimber C, et al. Variation in TCF7L2 influences therapeutic response to sulfonylureas: a GoDARTs study. Diabetes 2007; 56:2178-2182. A retrospective study suggesting that diabetic individuals with TCF7L2 variants respond differently to sulfonylureas than to metformin.
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(2007)
Diabetes
, vol.56
, pp. 2178-2182
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Pearson, E.R.1
Donnelly, L.A.2
Kimber, C.3
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51
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34248156160
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Effect of genetic variation in the organic cation transporter 1 (OCT1) on metformin action
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This article shows that normoglycemic individuals have differential hypoglycemic responses to metformin based on variation in OCT1
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Shu Y, Sheardown SA, Brown C, et al. Effect of genetic variation in the organic cation transporter 1 (OCT1) on metformin action. J Clin Invest 2007; 117:1422-1431. This article shows that normoglycemic individuals have differential hypoglycemic responses to metformin based on variation in OCT1.
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(2007)
J Clin Invest
, vol.117
, pp. 1422-1431
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Shu, Y.1
Sheardown, S.A.2
Brown, C.3
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