Silencing of filamin A gene expression inhibits Ca2+-sensing receptor signaling

FEBS Letters

Volumn 580, Issue 7, 2006, Pages 1795-1800

  Huang, Chunfa ^a   Wu, Zhenzhen ^a   Hujer, Kristine M ^a   Miller, R Tyler ^a  

^a NONE

Author keywords

Ca2+ sensing receptor; Filamin A; MAP kinase; Signaling; siRNA

Indexed keywords

CALCIUM SENSING RECEPTOR; FILAMIN A; G PROTEIN COUPLED RECEPTOR; MITOGEN ACTIVATED PROTEIN KINASE; SMALL INTERFERING RNA;

ARTICLE; GENE EXPRESSION; GENE SILENCING; IMMUNOBLOTTING; IMMUNOFLUORESCENCE; PRIORITY JOURNAL; PROTEIN FUNCTION;

CELL LINE; CONTRACTILE PROTEINS; GENE EXPRESSION REGULATION; GENE SILENCING; HUMANS; MAP KINASE SIGNALING SYSTEM; MICROFILAMENT PROTEINS; RECEPTORS, CALCIUM-SENSING; RECEPTORS, G-PROTEIN-COUPLED; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION;

EID: 33644895118     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.febslet.2006.02.035     Document Type: Article

References (25)

1. A. Lambrechts, M. Van Troys, and C. Ampe The actin cytoskeleton in normal and pathological cell motility Int. J. Biochem. Cell Biol. 36 2004 1890 1909
2. K.A. DeMali, K. Wennerberg, and K. Burridge Integrin signaling to the actin cytoskeleton Curr. Opin. Cell Biol. 15 2003 572 582
3. C. Wu, and S. Dedhar Integrin-linked kinase (ILK) and its interactors: a new paradigm for the coupling of extracellular matrix to actin cytoskeleton and signaling complexes J. Cell. Biol. 155 2001 505 510
4. S. Etienne-Manneville, and A. Hall Rho GTPases in cell biology Nature 420 2002 629 635
5. D.A. Calderwood, S.J. Shattil, and M.H. Ginsberg Integrins and actin filaments: reciprocal regulation of cell adhesion and signaling J. Biol. Chem. 275 2000 22607 22610
6. A. van der Flier, and A. Sonnenberg Structural and functional aspects of filamins Biochim. Biophys. Acta 1538 2001 99 117
7. T.P. Stossel, J. Condeelis, L. Cooley, J.H. Hartwig, A. Noegel, M. Schleicher, and S.S. Shapiro Filamins as integrators of cell mechanics and signalling Nature Rev. Mol. Cell Biol. 2 2001 138 145
8. C.C. Cunningham, J.B. Gorlin, D.J. Kwiatkowski, J.H. Hartwig, P.A. Janmey, H.R. Byers, and T.P. Stossel Actin-binding protein requirement for cortical stability and efficient locomotion Science 255 1992 325 327
9. V.L. Sheen, Y. Feng, D. Graham, T. Takafuta, S.S. Shapiro, and C.A. Walsh Filamin A and Filamin B are co-expressed within neurons during periods of neuronal migration and can physically interact Hum. Mol. Genet. 11 2002 2845 2854
10. S.P. Robertson, S.R. Twigg, A.J. Sutherland-Smith, V. Biancalana, R.J. Gorlin, D. Horn, S.J. Kenwrick, C.A. Kim, E. Morava, R. Newbury-Ecob, K.H. Orstavik, O.W. Quarrell, C.E. Schwartz, D.J. Shears, M. Suri, J. Kendrick-Jones, A.O. Wilkie OPD-spectrum Disorders Clinical Collaborative Group Localized mutations in the gene encoding the cytoskeletal protein filamin A cause diverse malformations in humans Nat. Genet. 33 2003 487 491
11. M. Li, J.C. Bermak, Z.W. Wang, and Q.Y. Zhou Modulation of dopamine D2 receptor signaling by actin-binding protein (ABP-280) Mol. Pharmacol. 57 2001 446 452
12. 3 receptors are linked to the actin cytoskeleton via interaction with filamin A Proc. Natl. Acad. Sci. USA 98 2001 5258 5263
13. T. Seck, B. Baron, and W.C. Horne Binding of filamin to the C-terminal tail of the calcitonin receptor controls recycling J. Biol. Chem. 278 2003 10408 10416
14. H. Awata, C. Huang, M.E. Handlogten, and R.T. Miller Interaction of the calcium-sensing receptor and filamin, a potential scaffolding protein J. Biol. Chem. 276 2001 34871 34879
15. G. Hjalm, R.J. MacLeod, O. Kifor, N. Chattopadhyay, and E.M. Brown Filamin-A binds to the carboxyl-terminal tail of the calcium-sensing receptor, an interaction that participates in CaR-mediated activation of mitogen-activated protein kinase J. Biol. Chem. 276 2001 34880 34887
16. 12, Rho, filamin-A, and the actin cytoskeleton J. Biol. Chem. 280 2005 22875 22882
17. A. Marti, Z. Luo, C. Cunningham, Y. Ohta, J. Hartwig, T.P. Stossel, J.M. Kyriakis, and J. Avruch Actin-binding protein-280 binds the stress-activated protein kinase (SAPK) activator SEK-1 and is required for tumor necrosis factor-α activation of SAPK in melanoma cells J. Biol. Chem. 272 1997 2620 2628
18. L.A. Flanagan, J. Chou, H. Falet, R. Neujahr, J.H. Hartwig, and T. Stossel Filamin A, the Arp2/3 complex, and the morphology and function of cortical actin filaments in human melanoma cells J. Cell Biol. 155 2001 511 517
19. S.M. Hammond, E. Bernstein, D. Beach, and G.J. Hannon An RNA-directed nuclease mediates post-transcriptional gene silencing in Drosophila cells Nature 404 2000 293 296
20. S.M. Elbashir, J. Harborth, W. Lendeckel, A. Yalcin, K. Weber, and T. Tuschl Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells Nature 411 2001 494 498
21. qα-dependent ERK-independent pathway J. Biol. Chem. 276 2001 13941 13948
22. Z. Wu, R. Tandon, J. Ziembicki, J. Nagano, K.M. Hujer, R.T. Miller, and C. Huang Role of ceramide in Ca2+-sensing receptor-induced apoptosis J. Lipid Res. 46 2005 1396 1404
23. K.M. Kim, R.R. Gainetdinov, S.A. Laporte, M.G. Caron, and L.S. Barak G protein-coupled receptor kinase regulates dopamine D3 receptor signaling by modulating the stability of a receptor-filamin-beta-arrestin complex. A case of autoreceptor regulation J. Biol. Chem. 280 2005 12774 12780
24. D. Brown, and S. Breton Sorting proteins to their target membranes Kidney Int. 57 2000 816 824
25. M. Zhang, and G.E. Breitwieser High affinity interaction with filamin A protects against calcium-sensing receptor degradation J. Biol. Chem. 280 2005 11140 11146