Amino acid-stimulated Ca2+ oscillations produced by the Ca 2+-sensing receptor are mediated by a phospholipase C/inositol 1,4,5-trisphosphate-independent pathway that requires G12, Rho, filamin-A, and the actin cytoskeleton

Journal of Biological Chemistry

Volumn 280, Issue 24, 2005, Pages 22875-22882

  Rey, Osvaldo ^a   Young, Steven H ^a   Yuan, Jingzhen ^a   Slice, Lee ^a   Rozengurt, Enrique ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; CALCIUM; CELLS; CHEMICAL ACTIVATION; ISOMERS; OSCILLATIONS; PHOSPHATES; POSITIVE IONS;

ACTIN; CYTOSKELETON; L-PHENYLALANINE; SIGNAL TRANSDUCTION;

PROTEINS;

ACTIN; AMINO ACID; CALCIUM; CALCIUM SENSING RECEPTOR; FILAMIN; FILAMIN A; G PROTEIN COUPLED RECEPTOR; GUANINE NUCLEOTIDE BINDING PROTEIN; INOSITOL 1,4,5 TRISPHOSPHATE; PHENYLALANINE; PHOSPHATIDYLINOSITOL 4,5 BISPHOSPHATE; PHOSPHOLIPASE C; RHO FACTOR; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CALCIUM CELL LEVEL; CALCIUM SIGNALING; CARBOXY TERMINAL SEQUENCE; HUMAN; HUMAN CELL; HYDROLYSIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN STABILITY; SECOND MESSENGER; SIGNAL TRANSDUCTION;

ACTINS; ALLOSTERIC SITE; AMINO ACIDS; BLOTTING, WESTERN; CALCIUM; CATALYSIS; CELL LINE; CONTRACTILE PROTEINS; CYTOSKELETON; DNA PRIMERS; DNA, COMPLEMENTARY; GTP-BINDING PROTEIN ALPHA SUBUNITS, G12-G13; HUMANS; INOSITOL 1,4,5-TRISPHOSPHATE; MICROFILAMENT PROTEINS; OSCILLOMETRY; PHENYLALANINE; PHOSPHOLIPASE C; PROTEIN CONFORMATION; PROTEIN KINASE C; RECEPTORS, CALCIUM-SENSING; RHO GTP-BINDING PROTEINS; SIGNAL TRANSDUCTION; TIME FACTORS; TRANSFECTION;

EID: 20744460194     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M503455200     Document Type: Article

References (55)

1. Brown, E. M., Gamba, G., Riccardi, D., Lombardi, M., Butters, R., Kifor, O., Sun, A., Hediger, M. A., Lytton, J., and Hebert, S. C. (1993) Nature 366, 575-580
2. Hebert, S. C., Brown, E. M., and Harris, H. W. (1997) J. Exp. Biol. 200, 295-302
3. Hendy, G. N., D'Souza-Li, L., Yang, B., Canaff, L., and Cole, D. E. (2000) Hum. Mutat. 16, 281-296
4. Ho, C., Conner, D. A., Pollak, M. R., Ladd, D. J., Kifor, O., Warren, H. B., Brown, E. M., Seidman, J. G., and Seidman, C. E. (1995) Nat. Genet. 11, 389-394
5. Quarles, L. D. (2003) Curr. Opin. Nephrol. Hypertens. 12, 349-355
6. Brown, E. M., and MacLeod, R. J. (2001) Physiol. Rev. 81, 239-297
7. Hofer, A. M., and Brown, E. M. (2003) Nat. Rev. Mol. Cell. Biol. 4, 530-538
8. Breitwieser, G. E., and Gama, L. (2001) Am. J. Physiol. 280, C1412-C1421
9. Young, S. H., and Rozengurt, E. (2002) Am. J. Physiol. 282, C1414-C1422
10. Conigrave, A. D., Quinn, S. J., and Brown, E. M. (2000) Trends Pharmacol. Sci. 21, 401-407
11. Young, S. H., Wu, S. V., and Rozengurt, E. (2002) J. Biol. Chem. 277, 46871-46876
12. Berridge, M. J., Bootman, M. D., and Roderick, H. L. (2003) Nat. Rev. Mol. Cell. Biol. 4, 517-529
13. Yuan, J., Slice, L. W., Gu, J., and Rozengurt, E. (2003) J. Biol. Chem. 278, 4882-4891
14. Rey, O., Young, S. H., Cantrell, D., and Rozengurt, E. (2001) J. Biol. Chem. 276, 32616-32626
15. Sinnett-Smith, J., Lunn, J. A., Leopoldt, D., and Rozengurt, E. (2001) Exp. Cell Res. 266, 292-302
16. Yuan, J., Slice, L. W., and Rozengurt, E. (2001) J. Biol. Chem. 276, 38619-38627
17. Rozen, S., and Skaletsky, H. J. (2000) in Bioinformatics Methods and Protocols: Methods in Molecular Biology (Krawetz, S., and Misener, S., eds) pp. 365-386, Humana Press, Totowa, NJ
18. Rey, O., Yuan, J., Young, S. H., and Rozengurt, E. (2003) J. Biol. Chem. 278, 23773-23785
19. Nash, M. S., Young, K. W., Willars, G. B., Challiss, R. A., and Nahorski, S. R. (2001) Biochem. J. 356, 137-142
20. Hirose, K., Kadowaki, S., Tanabe, M., Takeshima, H., and Iino, M. (1999) Science 284, 1527-1530
21. van der Wal, J., Habets, R., Varnai, P., Balla, T., and Jalink, K. (2001) J. Biol. Chem. 276, 15337-15344
22. Nash, M. S., Young, K. W., Challiss, R. A., and Nahorski, S. R. (2001) Nature 413, 381-382
23. Rey, O., Reeve, J. R., Jr., Zhukova, E., Sinnett-Smith, J., and Rozengurt, E. (2004) J. Biol. Chem. 279, 34361-34372
24. Oancea, E., and Meyer, T. (1998) Cell 95, 307-318
25. Waldron, R. T., Rey, O., Iglesias, T., Tugal, T., Cantrell, D., and Rozengurt, E. (2001) J. Biol. Chem. 276, 32606-32615
26. Waldron, R. T., and Rozengurt, E. (2003) J. Biol. Chem. 278, 154-163
27. Mochizuki, H., Ito, T., and Hidaka, H. (1993) J. Biol. Chem. 268, 9143-9147
28. Lorca, T., Cruzalegui, F. H., Fesquet, D., Cavadore, J. C., Méry, J., Means, A., and Dorée, M. (1993) Nature 366, 270-273
29. Valverde, A. M., Sinnett-Smith, J., Van Lint, J., and Rozengurt, E. (1994) Proc. Natl. Acad. Sci. U. S. A. 91, 8572-8576
30. Aida, K., Koishi, S., Tawata, M., and Onaya, T. (1995) Biochem. Biophys. Res. Commun. 214, 524-529
31. Butters, R. R., Jr., Chattopadhyay, N., Nielsen, P., Smith, C. P., Mithal, A., Kifor, O., Bai, M., Quinn, S., Goldsmith, P., Hurwitz, S., Krapcho, K., Busby, J., and Brown, E. M. (1997) J. Bone Miner. Res. 12, 568-579
32. Riccardi, D., Park, J., Lee, W. S., Gamba, G., Brown, E. M., and Hebert, S. C. (1995) Proc. Natl. Acad. Sci. U. S. A. 92, 131-135
33. Ward, D. T., and Riccardi, D. (2002) Pflugers Arch. Eur. J. Physiol. 445, 169-176
34. Patterson, R. L., van Rossum, D. B., and Gill, D. L. (1999) Cell 98, 487-499
35. Ribeiro, C. M., Reece, J., and Putney, J. W., Jr. (1997) J. Biol. Chem. 272, 26555-26561
36. Lunn, J. A., Wong, H., Rozengurt, E., and Walsh, J. H. (2000) Am. J. Physiol. 279, C2019-C2027
37. Burridge, K., and Wennerberg, K. (2004) Cell 116, 167-179
38. Aktories, K. (1997) J. Clin. Investig. 99, 827-829
39. Just, I., Wilm, M., Selzer, J., Rex, G., von Eichel-Streiber, C., Mann, M., and Aktories, K. (1995) J. Biol. Chem. 270, 13932-13936
40. Sekine, A., Fujiwara, M., and Narumiya, S. (1989) J. Biol. Chem. 264, 8602-8605
41. Awata, H., Huang, C., Handlogten, M. E., and Miller, R. T. (2001) J. Biol. Chem. 276, 34871-34879
42. Hjalm, G., MacLeod, R. J., Kifor, O., Chattopadhyay, N., and Brown, E. M. (2001) J. Biol. Chem. 276, 34880-34887
43. Pi, M., Spurney, R. F., Tu, Q., Hinson, T., and Quarles, L. D. (2002) Endocrinology 143, 3830-3838
44. Hooley, R., Yu, C. Y., Symons, M., and Barber, D. L. (1996) J. Biol. Chem. 271, 6152-6158
45. Klages, B., Brandt, U., Simon, M. I., Schultz, G., and Offermanns, S. (1999) J. Cell Biol. 144, 745-754
46. Plonk, S. G., Park, S. K., and Exton, J. H. (1998) J. Biol. Chem. 273, 4823-4826
47. Needham, L. K., and Rozengurt, E. (1998) J. Biol. Chem. 273, 14626-14632
48. Seasholtz, T. M., Majumdar, M., and Brown, J. H. (1999) Mol. Pharmacol. 55, 949-956
49. Slice, L. W., Walsh, J. H., and Rozengurt, E. (1999) J. Biol. Chem. 274, 27562-27566
50. Sah, V. P., Seasholtz, T. M., Sagi, S. A., and Brown, J. H. (2000) Annu. Rev. Pharmacol. Toxicol. 40, 459-489
51. Iglesias, T., Waldron, R. T., and Rozengurt, E. (1998) J. Biol. Chem. 273, 27662-27667
52. Mehta, D., Ahmmed, G. U., Paria, B. C., Holinstat, M., Voyno-Yasenetskaya, T., Tiruppathi, C., Minshall, R. D., and Malik, A. B. (2003) J. Biol. Chem. 278, 33492-33500
53. Kenakin, T. (2003) Trends Pharmacol. Sci. 24, 346-354
54. Kenakin, T. (1995) Trends Pharmacol. Sci. 16, 188-192
55. Kenakin, T. (1995) Trends Pharmacol. Sci. 16, 232-238