Allosteric activation of the extracellular Ca2+-sensing receptor by L-amino acids enhances ERK1/2 phosphorylation

Biochemical Journal

Volumn 404, Issue 1, 2007, Pages 141-149

  Lee, Heather J ^a   Mun, Hee Chang ^a   Lewis, Narelle C ^a   Crouch, Michael F ^b   Culverston, Emma L ^a   Mason, Rebecca S ^a   Conigrave, Arthur D ^a  

^a UNIVERSITY OF SYDNEY   (Australia)

^b TGR Biosciences and Australian Proteome Analysis Facility   (Australia)

Author keywords

Allosteric activator; Calcium sensing receptor; Extracellular calcium; Extracellular signal regulated kinase 1 2 (ERK1 2); L amino acid; Mitogen activated protein kinase (MAPK)

Indexed keywords

AMINO ACIDS; BIOASSAY; CALCIUM; ENZYME ACTIVITY; PHOSPHORYLATION; PHYSIOLOGY; POSITIVE IONS; STEREOSELECTIVITY;

ALLOSTERIC ACTIVATORS; CALCIUM SENSING RECEPTORS; HUMAN EMBRYONIC KIDNEY CELLS; INTRACELLULAR SIGNALLING ENZYMES; MITOGEN ACTIVATED PROTEIN KINASE (MAPK); PHENYLALANINE; WESTERN BLOTTING;

PROTEINS;

AMINO ACID; AROMATIC CARBOXYLIC ACID; CALCIUM SENSING RECEPTOR; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PHENYLALANINE; TRYPTOPHAN;

ALLOSTERISM; ARTICLE; CALCIUM MOBILIZATION; CONTROLLED STUDY; EXTRACELLULAR CALCIUM; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; QUANTITATIVE ASSAY; STEREOCHEMISTRY; WESTERN BLOTTING;

ALLOSTERIC REGULATION; AMINO ACID SUBSTITUTION; AMINO ACIDS; CALCIUM CHANNELS; CELL LINE; HUMANS; KIDNEY; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; PHENYLALANINE; PHOSPHORYLATION; RECOMBINANT PROTEINS;

EID: 34249076114     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/BJ20061826     Document Type: Article

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