Suppression of murine SLE by oral anti-CD3: Inducible CD4+CD25-LAP+ regulatory T cells control the expansion of IL-17+ follicular helper T cells

Lupus

Volumn 18, Issue 7, 2009, Pages 586-596

  Wu, Henry Yim ^a   Center, E M ^a   Tsokos, G C ^b   Weiner, Howard L ^a,b  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

Author keywords

CD4+CD25 LAP+ regulatory T cells; IL 17+ follicular helper T cells; Oral anti CD3; Spontaneous lupus

Indexed keywords

5' NUCLEOTIDASE; AUTOANTIBODY; CD4 ANTIGEN; CHEMOKINE RECEPTOR CXCR5; DOUBLE STRANDED DNA ANTIBODY; INTERLEUKIN 17; INTERLEUKIN 2 RECEPTOR ALPHA; LATENCY ASSOCIATED PEPTIDE; MONOCLONAL ANTIBODY CD3; SYNDECAN 1; TRANSFORMING GROWTH FACTOR BETA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBODY PRODUCTION; ARTICLE; CD4+ CD25+ T LYMPHOCYTE; CELL EXPANSION; CONTROLLED STUDY; DOWN REGULATION; DRUG MECHANISM; FEMALE; GLOMERULONEPHRITIS; IMMUNOREGULATION; MALE; MEMORY CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; REGULATORY T LYMPHOCYTE; SYSTEMIC LUPUS ERYTHEMATOSUS; TH17 CELL;

ADMINISTRATION, ORAL; ANIMALS; ANTIBODIES; ANTIGENS, CD3; AUTOANTIBODIES; B-LYMPHOCYTES; CELL PROLIFERATION; DISEASE MODELS, ANIMAL; DNA; FEMALE; GLOMERULONEPHRITIS; INTERLEUKIN-17; INTERLEUKIN-2 RECEPTOR ALPHA SUBUNIT; KIDNEY; LUPUS ERYTHEMATOSUS, SYSTEMIC; MALE; MICE; MICE, INBRED NZB; SPLEEN; T-LYMPHOCYTES, HELPER-INDUCER; T-LYMPHOCYTES, REGULATORY;

EID: 65649117701     PISSN: 09612033     EISSN: None     Source Type: Journal    
DOI: 10.1177/0961203308100511     Document Type: Article

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