Genetic, structural and functional properties of an IgG DNA-binding monoclonal antibody from a lupus patient with nephritis

European Journal of Immunology

Volumn 28, Issue 1, 1998, Pages 339-350

  Ravirajan, Chelliah T ^a   Rahman, Mohamad A ^a   Papadaki, Lucienne ^a   Griffiths, Meryl H ^a   Kalsi, Jatinderpal ^a   Martin, Andrew C R ^a   Ehrenstein, Michael R ^a   Latchman, David S ^a   Isenberg, David A ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

Antigen binding; Autoantibody; DNA sequence; Lupus; Nephritis

Indexed keywords

COMPLEMENTARY DNA; HISTONE; IMMUNOGLOBULIN G; IMMUNOGLOBULIN HEAVY CHAIN; IMMUNOGLOBULIN LAMBDA CHAIN; MONOCLONAL ANTIBODY;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CASE REPORT; COMBINED IMMUNODEFICIENCY; DNA BINDING; ELECTRON MICROSCOPY; FEMALE; HUMAN; HUMAN CELL; IMMUNOGLOBULIN GENE; IMMUNOGLOBULIN VARIABLE REGION; LUPUS ERYTHEMATOSUS NEPHRITIS; MOUSE; MYELOMA CELL; NONHUMAN; NUCLEOSOME; PERIPHERAL LYMPHOCYTE; PRIORITY JOURNAL; SOMATIC MUTATION; SYSTEMIC LUPUS ERYTHEMATOSUS;

AMINO ACID SEQUENCE; ANIMALS; ANTIBODIES, ANTINUCLEAR; ANTIBODIES, MONOCLONAL; ANTIBODY AFFINITY; ANTIBODY SPECIFICITY; ANTIGEN-ANTIBODY REACTIONS; AUTOIMMUNE DISEASES; BASE SEQUENCE; BINDING, COMPETITIVE; DNA; DNA, COMPLEMENTARY; DNA, SINGLE-STRANDED; FEMALE; GENES, IMMUNOGLOBULIN; HUMANS; HYBRIDOMAS; IMMUNOGLOBULIN G; IMMUNOGLOBULIN HEAVY CHAINS; KIDNEY; LUPUS NEPHRITIS; MICE; MICE, SCID; MICROSCOPY, ELECTRON; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PROTEIN CONFORMATION; PROTEINURIA; SEQUENCE ALIGNMENT; SEQUENCE HOMOLOGY, NUCLEIC ACID; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0031964947     PISSN: 00142980     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1521-4141(199801)28:01<339::AID-IMMU339>3.0.CO;2-C     Document Type: Article

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