Conversion of wild-type α-synuclein into mutant-type fibrils and its propagation in the presence of A30P mutant

Journal of Biological Chemistry

Volumn 284, Issue 12, 2009, Pages 7940-7950

  Yonetani, Motokuni ^a,b   Nonaka, Takashi ^a   Masuda, Masami ^a,b   Inukai, Yuki ^a,b   Oikawa, Takayuki ^a,b   Hisanaga, Shin Ichi ^b   Hasegawa, Masato ^a  

^a TOKYO METROPOLITAN INSTITUTE OF MEDICAL SCIENCE   (Japan)

^b TOKYO METROPOLITAN UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

BIOCHEMICAL ANALYSIS; CONFORMATIONAL CHANGE; FIBRILLIZATION; IMMUNOCHEMICAL ANALYSIS; MOLECULAR MECHANISM; PARKINSON DISEASE; SYNUCLEIN; ULTRACENTRIFUGATION EXPERIMENTS; WILD TYPES;

CENTRIFUGATION;

SEED;

ALANINE; ALPHA SYNUCLEIN; EPITOPE; MUTANT PROTEIN; PROLINE; PROTEINASE; ANTIBODY;

ANTIBODY SPECIFICITY; ARTICLE; BIOCHEMISTRY; CONTROLLED STUDY; DISEASE COURSE; FIBER; HUMAN; NONHUMAN; PARKINSON DISEASE; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN DEFECT; WILD TYPE; AMINO ACID SUBSTITUTION; CHEMISTRY; GENETICS; METABOLISM; MISSENSE MUTATION; PROTEIN QUATERNARY STRUCTURE;

ALPHA-SYNUCLEIN; AMINO ACID SUBSTITUTION; ANTIBODIES; EPITOPES; HUMANS; MUTATION, MISSENSE; PARKINSON DISEASE; PROTEIN STRUCTURE, QUATERNARY;

EID: 65549150887     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M807482200     Document Type: Article

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