-
1
-
-
0346119152
-
Breast cancer and the environment
-
Sasco AJ: Breast cancer and the environment. Horm Res 60: 50, 2003.
-
(2003)
Horm Res
, vol.60
, pp. 50
-
-
Sasco, A.J.1
-
2
-
-
0018915706
-
Cancer of the breast: The past decade
-
Henderson IC and Canellos GP: Cancer of the breast: The past decade. N Engl J Med 302: 17-30, 1990.
-
(1990)
N Engl J Med
, vol.302
, pp. 17-30
-
-
Henderson, I.C.1
Canellos, G.P.2
-
3
-
-
0023836871
-
Estrogens as a cause of human Cancer: The Richard and Hinda Rosenthal Foundation award Lecture
-
Henderson HS, Ross RK and Bernstein L: Estrogens as a cause of human Cancer: The Richard and Hinda Rosenthal Foundation award Lecture. Cancer Research 48: 246, 1988.
-
(1988)
Cancer Research
, vol.48
, pp. 246
-
-
Henderson, H.S.1
Ross, R.K.2
Bernstein, L.3
-
4
-
-
0021953918
-
Atypical hyperplastic lesions of the female breast; a longterm follow-up study
-
Page DL, Dupont WD, Rogers LW and Rados MS: Atypical hyperplastic lesions of the female breast; a longterm follow-up study. Cancer 55: 2698-2708,1985.
-
(1985)
Cancer
, vol.55
, pp. 2698-2708
-
-
Page, D.L.1
Dupont, W.D.2
Rogers, L.W.3
Rados, M.S.4
-
5
-
-
0242662678
-
Estrogen and its metabolites are carcinogenic agents in human breast epithelial cells
-
Russo J, Hasan Lareef M, Balogh G, Guo S and Russo IH: Estrogen and its metabolites are carcinogenic agents in human breast epithelial cells. J Steroid Biochem Mol Biol 87: 1-25, 2003.
-
(2003)
J Steroid Biochem Mol Biol
, vol.87
, pp. 1-25
-
-
Russo, J.1
Hasan Lareef, M.2
Balogh, G.3
Guo, S.4
Russo, I.H.5
-
6
-
-
0000856185
-
Aromatase and breast cancer
-
Chen S: Aromatase and breast cancer. Front Biosci 3: 922-933, 1998.
-
(1998)
Front Biosci
, vol.3
, pp. 922-933
-
-
Chen, S.1
-
7
-
-
0026530997
-
A prospective study of benign breast disease and the risk of breast cancer
-
London SJ, Connolly JL, Schnitt SJ and Colditz GA: A prospective study of benign breast disease and the risk of breast cancer. JAMA 267: 941-944, 1992.
-
(1992)
JAMA
, vol.267
, pp. 941-944
-
-
London, S.J.1
Connolly, J.L.2
Schnitt, S.J.3
Colditz, G.A.4
-
8
-
-
0030692641
-
Environmental estrogen stimulation of growth and estrogen receptor function in preneoplastic and cancerous human breast cell lines
-
Shekhar PVM, Werdell J and Barsrur VS: Environmental estrogen stimulation of growth and estrogen receptor function in preneoplastic and cancerous human breast cell lines. J Natl Cancer Inst 89: 1774-1782, 1997.
-
(1997)
J Natl Cancer Inst
, vol.89
, pp. 1774-1782
-
-
Shekhar, P.V.M.1
Werdell, J.2
Barsrur, V.S.3
-
9
-
-
64949140608
-
-
Dao TL: The role of the ovarian steroid hormones in mammary carcinogenesis. In: Hormones and Breast Cancer, (anbury repport no.8). Pike MC, Siiteri PK and Welsch CW (eds.). Cold Spring Harbor Laboratory Press, Cold Spring Harbor. NY, pp. 281-295, 1981.
-
Dao TL: The role of the ovarian steroid hormones in mammary carcinogenesis. In: Hormones and Breast Cancer, (anbury repport no.8). Pike MC, Siiteri PK and Welsch CW (eds.). Cold Spring Harbor Laboratory Press, Cold Spring Harbor. NY, pp. 281-295, 1981.
-
-
-
-
10
-
-
34247158270
-
Perinatal bisphenol A exposure increases estrogen sensitivity of the mammary gland in diverse mouse strains
-
Wadia PR, Vandenberg LN, Schaeberle CM, Rubin BS, Sonnenschein C and Soto AM: Perinatal bisphenol A exposure increases estrogen sensitivity of the mammary gland in diverse mouse strains. Environ Health Perspect 115: 592-598, 2007.
-
(2007)
Environ Health Perspect
, vol.115
, pp. 592-598
-
-
Wadia, P.R.1
Vandenberg, L.N.2
Schaeberle, C.M.3
Rubin, B.S.4
Sonnenschein, C.5
Soto, A.M.6
-
11
-
-
23844552517
-
Perinatal exposure to bisphenol-A alters peripubertal mammary gland development in mice
-
Muñoz-de-Toro M, Markey CM, Wadia PR, Luque EH, Rubin BS, Sonnenschein C and Soto AM: Perinatal exposure to bisphenol-A alters peripubertal mammary gland development in mice. Endocrinology 146: 4138-4147, 2005.
-
(2005)
Endocrinology
, vol.146
, pp. 4138-4147
-
-
Muñoz-de-Toro, M.1
Markey, C.M.2
Wadia, P.R.3
Luque, E.H.4
Rubin, B.S.5
Sonnenschein, C.6
Soto, A.M.7
-
12
-
-
34247118406
-
Induction of mammary gland ductal hyperplasias and carcinoma in situ following fetal bisphenol A exposure
-
Murray TJ, Maffini MV, Ucci AA, Sonnenschein C and Soto AM: Induction of mammary gland ductal hyperplasias and carcinoma in situ following fetal bisphenol A exposure. Reprod Toxicol 23: 383-390, 2007.
-
(2007)
Reprod Toxicol
, vol.23
, pp. 383-390
-
-
Murray, T.J.1
Maffini, M.V.2
Ucci, A.A.3
Sonnenschein, C.4
Soto, A.M.5
-
13
-
-
18144381249
-
Estrogen and growth factor receptor interactions in human breast and non-small cell lung cancer cells
-
Pietras RJ, Marquez DC, Chen HW, Tsai E, Weinberg O and Fishbein M: Estrogen and growth factor receptor interactions in human breast and non-small cell lung cancer cells. Steroids 70: 372-381, 2005.
-
(2005)
Steroids
, vol.70
, pp. 372-381
-
-
Pietras, R.J.1
Marquez, D.C.2
Chen, H.W.3
Tsai, E.4
Weinberg, O.5
Fishbein, M.6
-
14
-
-
27644469160
-
Effects of oestradiol and tamoxifen on VEGF, soluble VEGFR-1, and VEGFR-2 in breast cancer and endothelial cells
-
Garvin S, Nilsson UW and Dabrosin C: Effects of oestradiol and tamoxifen on VEGF, soluble VEGFR-1, and VEGFR-2 in breast cancer and endothelial cells. Br J Cancer 93: 1005-1010, 2005.
-
(2005)
Br J Cancer
, vol.93
, pp. 1005-1010
-
-
Garvin, S.1
Nilsson, U.W.2
Dabrosin, C.3
-
15
-
-
33846846385
-
Estrogen receptor regulates insulin-like growth factor-I receptor gene expression in breast tumor cells: Involvement of transcription factor Spl
-
Maor S, Mayer D, Yarden RI, Lee AV, Sarfstein R, Werner H and Papa MZ: Estrogen receptor regulates insulin-like growth factor-I receptor gene expression in breast tumor cells: involvement of transcription factor Spl. J Endocrinol 191: 605-612, 2006.
-
(2006)
J Endocrinol
, vol.191
, pp. 605-612
-
-
Maor, S.1
Mayer, D.2
Yarden, R.I.3
Lee, A.V.4
Sarfstein, R.5
Werner, H.6
Papa, M.Z.7
-
16
-
-
0037158891
-
Transcriptional activation by the oestrogen receptor alpha is modulated through inhibition of cyclin-dependent kinases
-
Redeuilh G, Attia A, Mester J and Sabbah M: Transcriptional activation by the oestrogen receptor alpha is modulated through inhibition of cyclin-dependent kinases. Oncogene 21: 5773-5782, 2002.
-
(2002)
Oncogene
, vol.21
, pp. 5773-5782
-
-
Redeuilh, G.1
Attia, A.2
Mester, J.3
Sabbah, M.4
-
17
-
-
0032031754
-
In situ aromatization enhances breast tumor estradiol levels and cellular proliferation
-
Yue W, Wang JP, Hamilton CJ, Demers LM and Santen RJ: In situ aromatization enhances breast tumor estradiol levels and cellular proliferation. Cancer Res 58: 927-932, 1998.
-
(1998)
Cancer Res
, vol.58
, pp. 927-932
-
-
Yue, W.1
Wang, J.P.2
Hamilton, C.J.3
Demers, L.M.4
Santen, R.J.5
-
18
-
-
33947137689
-
Estrogen promotes reversible epithelial-to mesenchymal-like transition and collective motility in MCF-7 breast cancer cells
-
Planas-Silva MD and Waltz PK: Estrogen promotes reversible epithelial-to mesenchymal-like transition and collective motility in MCF-7 breast cancer cells. J Steroid Biochem Mol Biol 104: 11-21, 2007.
-
(2007)
J Steroid Biochem Mol Biol
, vol.104
, pp. 11-21
-
-
Planas-Silva, M.D.1
Waltz, P.K.2
-
19
-
-
0024599859
-
Immunolocalization of aromatase, 17 alpha-hydroxylase and side-chain-cleavage cytochromes P-450 in the human ovary
-
Sasano H, Okamoto M, Mason JI, Simpson ER, Mendelson CR, Sasano N and Silverberg SG: Immunolocalization of aromatase, 17 alpha-hydroxylase and side-chain-cleavage cytochromes P-450 in the human ovary. Reprod Fertil 85: 163-169, 1989.
-
(1989)
Reprod Fertil
, vol.85
, pp. 163-169
-
-
Sasano, H.1
Okamoto, M.2
Mason, J.I.3
Simpson, E.R.4
Mendelson, C.R.5
Sasano, N.6
Silverberg, S.G.7
-
20
-
-
0028002466
-
Functional pathology of human ovarian steroidogenesis: Normal cycling ovary and steroidproducing neoplasms
-
Sasano H: Functional pathology of human ovarian steroidogenesis: Normal cycling ovary and steroidproducing neoplasms. Endo Pathol 5: 81-89, 1994.
-
(1994)
Endo Pathol
, vol.5
, pp. 81-89
-
-
Sasano, H.1
-
21
-
-
0037396439
-
Endocrine and intracrine sources of androgens in women: Inhibition of breast cancer and other roles of androgens and their precursor dehydroepiandrosterone
-
Labrie F, Luu-The V, Labrie C, Belanger A, Simard J, Lin SX and Pelletier G: Endocrine and intracrine sources of androgens in women: inhibition of breast cancer and other roles of androgens and their precursor dehydroepiandrosterone. Endocr Rev 24: 152-182, 2003.
-
(2003)
Endocr Rev
, vol.24
, pp. 152-182
-
-
Labrie, F.1
Luu-The, V.2
Labrie, C.3
Belanger, A.4
Simard, J.5
Lin, S.X.6
Pelletier, G.7
-
22
-
-
0029862593
-
Serum sex hormone levels after menopause and subsequent breast cancer
-
Berrino F, Muti P, Micheli A, Bolelli G, Krogh V, Sciajno R, Pisani P, Panico S and Secreto G: Serum sex hormone levels after menopause and subsequent breast cancer. J Natl Cancer Inst 88: 291-296, 1996.
-
(1996)
J Natl Cancer Inst
, vol.88
, pp. 291-296
-
-
Berrino, F.1
Muti, P.2
Micheli, A.3
Bolelli, G.4
Krogh, V.5
Sciajno, R.6
Pisani, P.7
Panico, S.8
Secreto, G.9
-
23
-
-
0030059217
-
Serum steroid hormone levels, sex hormone-binding globulin, and body mass index in the etiology of postmenopausal breast cancer
-
Lipworth L, Adami HO, Trichopoulos D, Carlstrom K and Mantzoros C: Serum steroid hormone levels, sex hormone-binding globulin, and body mass index in the etiology of postmenopausal breast cancer. Epidemiology 7: 96-100, 1996.
-
(1996)
Epidemiology
, vol.7
, pp. 96-100
-
-
Lipworth, L.1
Adami, H.O.2
Trichopoulos, D.3
Carlstrom, K.4
Mantzoros, C.5
-
24
-
-
0030932246
-
Relationship of serum dehydroepiandrosterone (DHEA), DHEA sulfate, and 5-androstene-3 beta, 17 beta-diol to risk of breast cancer in postmenopausal women
-
Dorgan JF, Stanczyk FZ, Longcope C, Stephenson Jr HE, Chang L, Miller R, Franz C, Falk RT and Kahle L: Relationship of serum dehydroepiandrosterone (DHEA), DHEA sulfate, and 5-androstene-3 beta, 17 beta-diol to risk of breast cancer in postmenopausal women. Cancer Epidemiol Biomarkers Prev 6: 177-181, 1997.
-
(1997)
Cancer Epidemiol Biomarkers Prev
, vol.6
, pp. 177-181
-
-
Dorgan, J.F.1
Stanczyk, F.Z.2
Longcope, C.3
Stephenson Jr, H.E.4
Chang, L.5
Miller, R.6
Franz, C.7
Falk, R.T.8
Kahle, L.9
-
25
-
-
0031712804
-
Intratumoral aromatase in human breast, endometrial, and ovarian malignancies
-
Sasano H and Harada N: Intratumoral aromatase in human breast, endometrial, and ovarian malignancies. Endocrine Reviews 19: 593-607, 1998.
-
(1998)
Endocrine Reviews
, vol.19
, pp. 593-607
-
-
Sasano, H.1
Harada, N.2
-
26
-
-
0026003175
-
Aromatase activity in breast tissue
-
Miller WR: Aromatase activity in breast tissue. J Steroid Biochem Mol Biol 39: 783-790, 1991.
-
(1991)
J Steroid Biochem Mol Biol
, vol.39
, pp. 783-790
-
-
Miller, W.R.1
-
29
-
-
0030800535
-
Aromatase in human bone tissue
-
Sasano H, Uzuki M, Sawai T, Nagura H, Matsunaga G, Kashimoto O and Harada N: Aromatase in human bone tissue. J Bone Miner Res 12: 1416-1423, 1997.
-
(1997)
J Bone Miner Res
, vol.12
, pp. 1416-1423
-
-
Sasano, H.1
Uzuki, M.2
Sawai, T.3
Nagura, H.4
Matsunaga, G.5
Kashimoto, O.6
Harada, N.7
-
30
-
-
0027157709
-
Effect of androstenedione on growth of untransfected and aromatase-transfected MCF-7 cells in culture
-
Santner SJ, Chen S, Zhou D, Korsunsky Z, Martel J and Santen RJ. Effect of androstenedione on growth of untransfected and aromatase-transfected MCF-7 cells in culture. J Steroid Biochem Mol Biol 44: 611-616, 1993.
-
(1993)
J Steroid Biochem Mol Biol
, vol.44
, pp. 611-616
-
-
Santner, S.J.1
Chen, S.2
Zhou, D.3
Korsunsky, Z.4
Martel, J.5
Santen, R.J.6
-
31
-
-
0034016224
-
Comparison of estrogen concentrations, estrone sulfatase and aromatase activities in normal, and in cancerous, human breast tissues
-
Chetrite GS, Cortes-Prieto J, Philippe JC, Wright F and Pasqualini JR: Comparison of estrogen concentrations, estrone sulfatase and aromatase activities in normal, and in cancerous, human breast tissues. J Steroid Biochem Mol Biol 72: 23-27, 2000.
-
(2000)
J Steroid Biochem Mol Biol
, vol.72
, pp. 23-27
-
-
Chetrite, G.S.1
Cortes-Prieto, J.2
Philippe, J.C.3
Wright, F.4
Pasqualini, J.R.5
-
32
-
-
0029872530
-
Concentrations of estrone, estradiol, and estrone sulfate and evaluation of sulfatase and aromatase activities in pre- and postmenopausal breast cancer patients
-
Pasqualini JR, Chetrite G, Blacker C, Feinstein MC, Delalonde L, Talbi M and Maloche C: Concentrations of estrone, estradiol, and estrone sulfate and evaluation of sulfatase and aromatase activities in pre- and postmenopausal breast cancer patients. J Clin Endocr Metab 81: 1460-1464, 1996.
-
(1996)
J Clin Endocr Metab
, vol.81
, pp. 1460-1464
-
-
Pasqualini, J.R.1
Chetrite, G.2
Blacker, C.3
Feinstein, M.C.4
Delalonde, L.5
Talbi, M.6
Maloche, C.7
-
33
-
-
2542492928
-
The selective estrogen enzyme modulators in breast cancer: A review
-
Pasqualini JR: The selective estrogen enzyme modulators in breast cancer: a review. Biochimica et Biophysica Acta 1654: 123-143, 2004.
-
(2004)
Biochimica et Biophysica Acta
, vol.1654
, pp. 123-143
-
-
Pasqualini, J.R.1
-
34
-
-
0024419217
-
In situ oestrone synthesis in normal breast and breast tumour tissues: Effect of treatment with 4-hydroxyandrostenedione
-
Reed MJ, Owen AM, Lai LC, Coldham NG, Ghilchik MW, Shaikh NA and James VHT: In situ oestrone synthesis in normal breast and breast tumour tissues: effect of treatment with 4-hydroxyandrostenedione. Int J Cancer 44: 233-237, 1989.
-
(1989)
Int J Cancer
, vol.44
, pp. 233-237
-
-
Reed, M.J.1
Owen, A.M.2
Lai, L.C.3
Coldham, N.G.4
Ghilchik, M.W.5
Shaikh, N.A.6
James, V.H.T.7
-
36
-
-
0038175996
-
High expression of steroid sulfatase mRNA predicts poor prognosis in patients with estrogen receptor-positive breast cancer
-
Miyoshi Y, Ando A, Hasegawa S, Ishitobi M, Taguchi T, Tamaki Y and Noguchi S: High expression of steroid sulfatase mRNA predicts poor prognosis in patients with estrogen receptor-positive breast cancer. Clin Cancer Res 9: 2288-2293, 2003.
-
(2003)
Clin Cancer Res
, vol.9
, pp. 2288-2293
-
-
Miyoshi, Y.1
Ando, A.2
Hasegawa, S.3
Ishitobi, M.4
Taguchi, T.5
Tamaki, Y.6
Noguchi, S.7
-
37
-
-
9044254525
-
P450 superfamily: Update on new sequences, gene mapping, accession numbers and nomenclature
-
Nelson DR, Koymans L, Kamataki T, stegeman JJ, Feyereisen R, Waxman DJ, Waterman MR, Gotoh O, Coon MJ, Estabrook RW, Gunsalus IC and Nebert DW: P450 superfamily: Update on new sequences, gene mapping, accession numbers and nomenclature. Pharmacogenetics 6: 1-42, 1996.
-
(1996)
Pharmacogenetics
, vol.6
, pp. 1-42
-
-
Nelson, D.R.1
Koymans, L.2
Kamataki, T.3
stegeman, J.J.4
Feyereisen, R.5
Waxman, D.J.6
Waterman, M.R.7
Gotoh, O.8
Coon, M.J.9
Estabrook, R.W.10
Gunsalus, I.C.11
Nebert, D.W.12
-
38
-
-
0023846054
-
-
Chen SA, Besman MJ, Sparkes RS, Zollman S, Klisak I, Mohandas T, Hall PF and Shively JE: Human aromatase: cDNA cloning, Southern blot analysis, and assignment of the gene to chromosome 15. DNA 7: 27-38, 1988.
-
Chen SA, Besman MJ, Sparkes RS, Zollman S, Klisak I, Mohandas T, Hall PF and Shively JE: Human aromatase: cDNA cloning, Southern blot analysis, and assignment of the gene to chromosome 15. DNA 7: 27-38, 1988.
-
-
-
-
39
-
-
0028332035
-
Aromatase cytochrome P450, the enzyme responsible for estrogen biosynthesis
-
Simpson ER, Mahendroo MS, Means GD, Kilgore MW, Hinshelwood MM, Graham-Lorence S, Amarneh B, Ito Y, Fisher CR, Michael MD, Mendelson CR and Bulun SE: Aromatase cytochrome P450, the enzyme responsible for estrogen biosynthesis. Endocr Rev 15: 342-355, 1994.
-
(1994)
Endocr Rev
, vol.15
, pp. 342-355
-
-
Simpson, E.R.1
Mahendroo, M.S.2
Means, G.D.3
Kilgore, M.W.4
Hinshelwood, M.M.5
Graham-Lorence, S.6
Amarneh, B.7
Ito, Y.8
Fisher, C.R.9
Michael, M.D.10
Mendelson, C.R.11
Bulun, S.E.12
-
40
-
-
0034751150
-
A highly complex organization of the regulatory region of the human CYP 19 (Aromatase) gene revealed by the Human Genome Project
-
Sebastian S and Bulun SE: A highly complex organization of the regulatory region of the human CYP 19 (Aromatase) gene revealed by the Human Genome Project. J Clin Endocrinol Metab 86: 4600-4602, 2001.
-
(2001)
J Clin Endocrinol Metab
, vol.86
, pp. 4600-4602
-
-
Sebastian, S.1
Bulun, S.E.2
-
41
-
-
0036193893
-
Aromatase - a brief overview
-
Simpson ER, Clyne C, Rubin G, Boon WC, Robertson K, Britt K, Speed C and Jones M: Aromatase - a brief overview. Annu Rev Physiol 64: 93-127, 2002.
-
(2002)
Annu Rev Physiol
, vol.64
, pp. 93-127
-
-
Simpson, E.R.1
Clyne, C.2
Rubin, G.3
Boon, W.C.4
Robertson, K.5
Britt, K.6
Speed, C.7
Jones, M.8
-
42
-
-
0242457714
-
Sources of estrogen and their importance
-
Simpson ER: Sources of estrogen and their importance. J Steroid Biochem Mol Biol 86: 225-230, 2003.
-
(2003)
J Steroid Biochem Mol Biol
, vol.86
, pp. 225-230
-
-
Simpson, E.R.1
-
44
-
-
0034749898
-
Minireview: Aromatase and the regulation of estrogen biosynthesis- some new perspectives
-
Simpson ER and Davis SR: Minireview: Aromatase and the regulation of estrogen biosynthesis- some new perspectives. Endocrinology 142: 4589-4594, 2001.
-
(2001)
Endocrinology
, vol.142
, pp. 4589-4594
-
-
Simpson, E.R.1
Davis, S.R.2
-
45
-
-
0036794381
-
Cloning and characterization of a novel endothelial promoter of the human CYP19 (aromatase P450) gene that is up-regulated in breast cancer tissue
-
Sebastian S, Takayama K, Shozu M and Bulun SE: Cloning and characterization of a novel endothelial promoter of the human CYP19 (aromatase P450) gene that is up-regulated in breast cancer tissue. Mol Endocrinol 16: 2243-2254, 2002.
-
(2002)
Mol Endocrinol
, vol.16
, pp. 2243-2254
-
-
Sebastian, S.1
Takayama, K.2
Shozu, M.3
Bulun, S.E.4
-
46
-
-
0027099861
-
A unique aromatase (P-450arom) mRNA formed by alternative use of tissue-specific exons 1 in human skin fibroblasts
-
Harada N: A unique aromatase (P-450arom) mRNA formed by alternative use of tissue-specific exons 1 in human skin fibroblasts. Biochem Biophys Res Commun 189: 1001-1007, 1993.
-
(1993)
Biochem Biophys Res Commun
, vol.189
, pp. 1001-1007
-
-
Harada, N.1
-
47
-
-
0030266161
-
Aromatase gene expression and its exon I usage in human breast tumors. Detection of aromatase messenger RNA by reverse transcription-polymerase chain reaction (RT-PCR)
-
Zhou C, Zhou D, Esteban J, Murai J, Siiteri P.K, Wilczynski S and Chen S: Aromatase gene expression and its exon I usage in human breast tumors. Detection of aromatase messenger RNA by reverse transcription-polymerase chain reaction (RT-PCR). J Steroid Biochem Mol Biol 59: 163-171, 1996.
-
(1996)
J Steroid Biochem Mol Biol
, vol.59
, pp. 163-171
-
-
Zhou, C.1
Zhou, D.2
Esteban, J.3
Murai, J.4
Siiteri, P.K.5
Wilczynski, S.6
Chen, S.7
-
48
-
-
0031120019
-
Endocrine disorders associated with inappropriately high aromatase expression
-
Bulun SE, Noble LS, Takayama K, Michael MD, Agarwal V, Fisher C, Zhao Y, Hinshelwood MM, Ito Y and Simpson ER: Endocrine disorders associated with inappropriately high aromatase expression. J Steroid Biochem Mol Biol 61: 133-139, 1997.
-
(1997)
J Steroid Biochem Mol Biol
, vol.61
, pp. 133-139
-
-
Bulun, S.E.1
Noble, L.S.2
Takayama, K.3
Michael, M.D.4
Agarwal, V.5
Fisher, C.6
Zhao, Y.7
Hinshelwood, M.M.8
Ito, Y.9
Simpson, E.R.10
-
49
-
-
0030635820
-
Cytochromes P450 11: Expression of the CYP19 (aromatase) gene: an unusual case of alternative promoter usage
-
Simpson ER, Michael MD, Agarwal VR, Hinshelwood MM, Bulun SE and Zhao Y: Cytochromes P450 11: expression of the CYP19 (aromatase) gene: an unusual case of alternative promoter usage. FASEB J 11: 29-36, 1997.
-
(1997)
FASEB J
, vol.11
, pp. 29-36
-
-
Simpson, E.R.1
Michael, M.D.2
Agarwal, V.R.3
Hinshelwood, M.M.4
Bulun, S.E.5
Zhao, Y.6
-
50
-
-
0027362649
-
Tissue-specific expression of the human aromatase cytochrome P-450 gene by alternative use of multiple exons 1 and promoters, and switching of tissuespecific exons 1 in carcinogenesis
-
Harada N, Utsumi T and Takagi Y: Tissue-specific expression of the human aromatase cytochrome P-450 gene by alternative use of multiple exons 1 and promoters, and switching of tissuespecific exons 1 in carcinogenesis. Proc Natl Acad Sci USA 90: 11312-11316, 1993.
-
(1993)
Proc Natl Acad Sci USA
, vol.90
, pp. 11312-11316
-
-
Harada, N.1
Utsumi, T.2
Takagi, Y.3
-
51
-
-
0026550423
-
Detection of intratumoral aromatase in breast carcinomas
-
Esteban JM, Warsi Z, Haniu M, Hall P, Shively JE and Chen S: Detection of intratumoral aromatase in breast carcinomas. Am J Pathol 140: 337-343, 1992.
-
(1992)
Am J Pathol
, vol.140
, pp. 337-343
-
-
Esteban, J.M.1
Warsi, Z.2
Haniu, M.3
Hall, P.4
Shively, J.E.5
Chen, S.6
-
52
-
-
0028787970
-
Aromatase activity and interleukin 6 production by normal and malignant breast tissues
-
Purohit A, Ghilchik MW, Duncan LJ, Wang DY, Singh A, Walker MM and Reed MJ: Aromatase activity and interleukin 6 production by normal and malignant breast tissues. J Clin Endocrinol Metab 80: 3052-3058, 1995.
-
(1995)
J Clin Endocrinol Metab
, vol.80
, pp. 3052-3058
-
-
Purohit, A.1
Ghilchik, M.W.2
Duncan, L.J.3
Wang, D.Y.4
Singh, A.5
Walker, M.M.6
Reed, M.J.7
-
53
-
-
0031126176
-
Control of aromatase in breast tumours: The role of the immune system
-
Singh A, Purohit A, Duncan LJ, Mokbel K, Ghilchik MW and Reed MJ: Control of aromatase in breast tumours: the role of the immune system. J Steroid Biochem Mol Biol 61: 185-192, 1997.
-
(1997)
J Steroid Biochem Mol Biol
, vol.61
, pp. 185-192
-
-
Singh, A.1
Purohit, A.2
Duncan, L.J.3
Mokbel, K.4
Ghilchik, M.W.5
Reed, M.J.6
-
54
-
-
0026557138
-
Interleukin-1 and interleukin-6 in breast cyst fluid: Their role in regulating aromatase activity in breast cancer cells
-
Reed MJ, Coldham NG, Patel SR, Ghilchik MW and James VHT: Interleukin-1 and interleukin-6 in breast cyst fluid: their role in regulating aromatase activity in breast cancer cells. J Endocrinol 132: R5-R8, 1992.
-
(1992)
J Endocrinol
, vol.132
-
-
Reed, M.J.1
Coldham, N.G.2
Patel, S.R.3
Ghilchik, M.W.4
James, V.H.T.5
-
55
-
-
0002499936
-
Sulphatase inhibitors: The rationale for the development of a new endocrine therapy
-
Reed MJ and Purohit A: Sulphatase inhibitors: the rationale for the development of a new endocrine therapy. Rev Endocr Rel Cancer 45: 51-62, 1993.
-
(1993)
Rev Endocr Rel Cancer
, vol.45
, pp. 51-62
-
-
Reed, M.J.1
Purohit, A.2
-
56
-
-
0027193474
-
Factors influencing aromatase activity in the breast
-
Miller WR and Mullen P: Factors influencing aromatase activity in the breast. J Steroid Biochem Molec Biol 44: 597-604, 1993.
-
(1993)
J Steroid Biochem Molec Biol
, vol.44
, pp. 597-604
-
-
Miller, W.R.1
Mullen, P.2
-
57
-
-
0029002074
-
Aromatase P450 gene expression in human adipose tissue
-
Zhao Y, Nichols JE, Bulnn SE, Mendelson CR and Simpson ER: Aromatase P450 gene expression in human adipose tissue. J Biol Chem 270: 16449-16457, 1995.
-
(1995)
J Biol Chem
, vol.270
, pp. 16449-16457
-
-
Zhao, Y.1
Nichols, J.E.2
Bulnn, S.E.3
Mendelson, C.R.4
Simpson, E.R.5
-
58
-
-
0028880991
-
IL-6sR: Release from MCF-7 breast cancer cells and role in regulating peripheral oestrogen synthesis
-
Singh A, Purohit A, Wang DY, Duncan LJ, Ghilchik MW and Reed MJ: IL-6sR: release from MCF-7 breast cancer cells and role in regulating peripheral oestrogen synthesis. J Endocrinol 147: R9-R12, 1995.
-
(1995)
J Endocrinol
, vol.147
-
-
Singh, A.1
Purohit, A.2
Wang, D.Y.3
Duncan, L.J.4
Ghilchik, M.W.5
Reed, M.J.6
-
59
-
-
0028577281
-
Stimulation of aromatase activity in breast fibroblasts by tumour necrosis factor α
-
Macdiarmid F, Wang DY, Duncan LJ, Purohit A, Ghilchik MW and Reed MJ: Stimulation of aromatase activity in breast fibroblasts by tumour necrosis factor α. Molec Cell Endocr 106: 17-21, 1994.
-
(1994)
Molec Cell Endocr
, vol.106
, pp. 17-21
-
-
Macdiarmid, F.1
Wang, D.Y.2
Duncan, L.J.3
Purohit, A.4
Ghilchik, M.W.5
Reed, M.J.6
-
60
-
-
0035266474
-
TNFalpha and IL-11 secreted by malignant breast epithelial cells inhibit adipocyte differentiation by selectively down-regulating C/EBPalpha and PPARgamma: Mechanism of desmoplastic reaction
-
Meng L, Zhou J, Hironobu S, Suzuki T, Zeitoun K and Bulun S: TNFalpha and IL-11 secreted by malignant breast epithelial cells inhibit adipocyte differentiation by selectively down-regulating C/EBPalpha and PPARgamma: mechanism of desmoplastic reaction. Cancer Res 61: 2250-2255, 2001.
-
(2001)
Cancer Res
, vol.61
, pp. 2250-2255
-
-
Meng, L.1
Zhou, J.2
Hironobu, S.3
Suzuki, T.4
Zeitoun, K.5
Bulun, S.6
-
61
-
-
0029820178
-
Use of alternative promoters to express the aromatase P450 (CYP19) gene in breast adipose tissues of cancer-free and breast cancer patients
-
Agarwal V, Bulun SE, Leitch M, Rohrich R and Simpson ER: Use of alternative promoters to express the aromatase P450 (CYP19) gene in breast adipose tissues of cancer-free and breast cancer patients. J Clin Endocrinol Metab 81: 3843-3849, 1996.
-
(1996)
J Clin Endocrinol Metab
, vol.81
, pp. 3843-3849
-
-
Agarwal, V.1
Bulun, S.E.2
Leitch, M.3
Rohrich, R.4
Simpson, E.R.5
-
62
-
-
0031120091
-
Transcriptional regulation of CYP19 (aromatase) gene expression in adipose stromal cells in primary culture
-
Zhao Y, Agarwal VR, Mendelsohn CR and Simpson ER: Transcriptional regulation of CYP19 (aromatase) gene expression in adipose stromal cells in primary culture. J Steroid Biochem Mol Biol 61: 203-210, 1997.
-
(1997)
J Steroid Biochem Mol Biol
, vol.61
, pp. 203-210
-
-
Zhao, Y.1
Agarwal, V.R.2
Mendelsohn, C.R.3
Simpson, E.R.4
-
63
-
-
0033011611
-
The regulation of aromatase activity in breast fibroblasts: The role of interleukin- 6 and prostaglandin E2
-
Singh A, Purohit A, Ghilchik MW and Reed MJ: The regulation of aromatase activity in breast fibroblasts: the role of interleukin- 6 and prostaglandin E2. Endocr-Relat Cancer 6: 139-147, 1999.
-
(1999)
Endocr-Relat Cancer
, vol.6
, pp. 139-147
-
-
Singh, A.1
Purohit, A.2
Ghilchik, M.W.3
Reed, M.J.4
-
64
-
-
0023519279
-
The importance of local synthesis of estrogen within the breast
-
Miller WR and O'Neill JS: The importance of local synthesis of estrogen within the breast. Steroids 50: 537-547, 1987.
-
(1987)
Steroids
, vol.50
, pp. 537-547
-
-
Miller, W.R.1
O'Neill, J.S.2
-
65
-
-
0027131199
-
A link between breast cancer and local estrogen biosynthesis suggested by quantification of breast adipose tissue aromatase cytochrome P450 transcripts using competitive polymerase chain reaction after reverse transcription
-
Bulun SE, Price TM, Aitken J, Mahendroo MS and Simpson ER: A link between breast cancer and local estrogen biosynthesis suggested by quantification of breast adipose tissue aromatase cytochrome P450 transcripts using competitive polymerase chain reaction after reverse transcription. J Clin Endocrinol Metab 77: 1622-1628, 1993.
-
(1993)
J Clin Endocrinol Metab
, vol.77
, pp. 1622-1628
-
-
Bulun, S.E.1
Price, T.M.2
Aitken, J.3
Mahendroo, M.S.4
Simpson, E.R.5
-
66
-
-
0029887272
-
Presence of alternatively spliced transcripts of aromatase gene in human breast cancer
-
Utsumi T, Harada N, Maruta M and Takagi Y: Presence of alternatively spliced transcripts of aromatase gene in human breast cancer. J Clin Endocrinol Metab 81: 2344-2349, 1996.
-
(1996)
J Clin Endocrinol Metab
, vol.81
, pp. 2344-2349
-
-
Utsumi, T.1
Harada, N.2
Maruta, M.3
Takagi, Y.4
-
67
-
-
0023509164
-
Aromatase activity in normal breast and breast tumor tissues: In vivo and in vitro studies
-
James VHT, McNeill J M, Lai LC, Newton CJ, Ghilchik MW and Reed MJ: Aromatase activity in normal breast and breast tumor tissues: in vivo and in vitro studies. Steroids 50: 269-279, 1987.
-
(1987)
Steroids
, vol.50
, pp. 269-279
-
-
James, V.H.T.1
McNeill, J.M.2
Lai, L.C.3
Newton, C.J.4
Ghilchik, M.W.5
Reed, M.J.6
-
68
-
-
0025089197
-
Stable expression of human aromatase cDNA in mammalian cells - A useful system for aromatase inhibitor screening
-
Zhou D, Pompon D and Chen S: Stable expression of human aromatase cDNA in mammalian cells - A useful system for aromatase inhibitor screening. Cancer Res 50: 6949-6954, 1990.
-
(1990)
Cancer Res
, vol.50
, pp. 6949-6954
-
-
Zhou, D.1
Pompon, D.2
Chen, S.3
-
69
-
-
0027985528
-
A new nude mouse model for post.menopausal breast cancer using MCF-7 cells transfected with the htmmn aromatase gene
-
Yue W, Zhou D, Chen S and Brodie A: A new nude mouse model for post.menopausal breast cancer using MCF-7 cells transfected with the htmmn aromatase gene. Cancer Res 54: 5092-5095, 1994.
-
(1994)
Cancer Res
, vol.54
, pp. 5092-5095
-
-
Yue, W.1
Zhou, D.2
Chen, S.3
Brodie, A.4
-
70
-
-
0028054778
-
Biological effects of stable overexpression of aromatase in human hormone-dependent breast cancer ceils
-
Macaulay VM, Nicholls J E, GledhiU J, Rowlands MG, Dowsett M and Ashworth A: Biological effects of stable overexpression of aromatase in human hormone-dependent breast cancer ceils. Br J Cancer 69: 77-83, 1994.
-
(1994)
Br J Cancer
, vol.69
, pp. 77-83
-
-
Macaulay, V.M.1
Nicholls, J.E.2
GledhiU, J.3
Rowlands, M.G.4
Dowsett, M.5
Ashworth, A.6
-
71
-
-
33747588055
-
The role of aromatase and 17-beta hydroxysteroid dehydrogenase type 1 mRNA expression in predicting the clinical outcome of human breast cancer
-
Salhab M, Reed MJ, Al Sarakbi W, Jiang WG and Mokbel K: The role of aromatase and 17-beta hydroxysteroid dehydrogenase type 1 mRNA expression in predicting the clinical outcome of human breast cancer. Breast Cancer Res Treat 99: 155-162, 2006.
-
(2006)
Breast Cancer Res Treat
, vol.99
, pp. 155-162
-
-
Salhab, M.1
Reed, M.J.2
Al Sarakbi, W.3
Jiang, W.G.4
Mokbel, K.5
-
72
-
-
0025684712
-
Relationship between tumor aromatase activity, tumor characteristics and response to therapy, fr
-
Miller WR, Anderson TJ and Lack WJL: Relationship between tumor aromatase activity, tumor characteristics and response to therapy, fr. Steroid Biochem. Molec Biol 37: 1055-1059, 1990.
-
(1990)
Steroid Biochem. Molec Biol
, vol.37
, pp. 1055-1059
-
-
Miller, W.R.1
Anderson, T.J.2
Lack, W.J.L.3
-
73
-
-
0028302746
-
Immunolocalization of aromatase and other steroidogenic enzymes in human breast disorders
-
Sasano H, Nagura H, Harada N, Goukon Y and Kimyra M: Immunolocalization of aromatase and other steroidogenic enzymes in human breast disorders. Hure Pathol 25: 530-535, 1994.
-
(1994)
Hure Pathol
, vol.25
, pp. 530-535
-
-
Sasano, H.1
Nagura, H.2
Harada, N.3
Goukon, Y.4
Kimyra, M.5
-
74
-
-
0035988017
-
Semi quantitative immunohistochemical analysis of aromatase expression in ductal carcinoma in situ of the breast
-
Zhang Z, Yamashita H, Toyama T, Hara Y, Omoto Y, Sugiura H, Kobayashi S, Harada N and Iwase H: Semi quantitative immunohistochemical analysis of aromatase expression in ductal carcinoma in situ of the breast. Breast Cancer Res Treat 74: 47-53, 2002.
-
(2002)
Breast Cancer Res Treat
, vol.74
, pp. 47-53
-
-
Zhang, Z.1
Yamashita, H.2
Toyama, T.3
Hara, Y.4
Omoto, Y.5
Sugiura, H.6
Kobayashi, S.7
Harada, N.8
Iwase, H.9
-
76
-
-
0037157603
-
Anastrozole alone or in combination with tamoxifen versus tamoxifen alone for adjuvant treatment of postmenopausal women with early breast cancer: First results of the ATAC randomised trial
-
The ATAC (Arimidex Tamoxifen alone or in Combination) Trialists' Group
-
The ATAC (Arimidex Tamoxifen alone or in Combination) Trialists' Group, Anastrozole alone or in combination with tamoxifen versus tamoxifen alone for adjuvant treatment of postmenopausal women with early breast cancer: first results of the ATAC randomised trial, Lancet 359: 2131-2139, 2002.
-
(2002)
Lancet
, vol.359
, pp. 2131-2139
-
-
-
78
-
-
0036807501
-
The evolving role of aromatase inhibitors in breast cancer
-
Mokbel K: The evolving role of aromatase inhibitors in breast cancer. Int J Clin Oncol 7: 279-283, 2002.
-
(2002)
Int J Clin Oncol
, vol.7
, pp. 279-283
-
-
Mokbel, K.1
-
79
-
-
33749428878
-
Adjuvant endocrine therapy for postmenopausal breast cancer in the era of aromatase inhibitors: An update
-
Mokbel R, Karat I and Mokbel K: Adjuvant endocrine therapy for postmenopausal breast cancer in the era of aromatase inhibitors: an update. Int Semin Surg Oncol 3: 31, 2006.
-
(2006)
Int Semin Surg Oncol
, vol.3
, pp. 31
-
-
Mokbel, R.1
Karat, I.2
Mokbel, K.3
-
80
-
-
29544433211
-
Breast International Group (BIG) 1-98 Collaborative Group. A comparison of letrozole and tamoxifen in postmenopausal women with early breast cancer
-
Thurlimann B, Keshaviah A, Coates AS, Mouridsen H, Mauriac L, Forbes JF, Paridaens R, Castiglione-Gertsch M, Gelber RD, Rabaglio M, Smith I, Wardly A, Price KN and Goldhirsch A: Breast International Group (BIG) 1-98 Collaborative Group. A comparison of letrozole and tamoxifen in postmenopausal women with early breast cancer. N Engl J Med 353: 2747-2757, 2005.
-
(2005)
N Engl J Med
, vol.353
, pp. 2747-2757
-
-
Thurlimann, B.1
Keshaviah, A.2
Coates, A.S.3
Mouridsen, H.4
Mauriac, L.5
Forbes, J.F.6
Paridaens, R.7
Castiglione-Gertsch, M.8
Gelber, R.D.9
Rabaglio, M.10
Smith, I.11
Wardly, A.12
Price, K.N.13
Goldhirsch, A.14
-
81
-
-
0024361957
-
Characterization of cDNAs for human estradiol 17beta-dehydrogenase and assignment of the gene to chromosome 17: Evidence of two mRNA species with distinct 50 -termini in human placenta
-
Luu-The V, Labrie C, Zhao HF, Couet J, Lachance Y, Simard J, Leblanc G, Cote J, Berube D, Gagne R and Labrie F: Characterization of cDNAs for human estradiol 17beta-dehydrogenase and assignment of the gene to chromosome 17: evidence of two mRNA species with distinct 50 -termini in human placenta. J Mol Endocrinol 3: 1301-1309, 1989.
-
(1989)
J Mol Endocrinol
, vol.3
, pp. 1301-1309
-
-
Luu-The, V.1
Labrie, C.2
Zhao, H.F.3
Couet, J.4
Lachance, Y.5
Simard, J.6
Leblanc, G.7
Cote, J.8
Berube, D.9
Gagne, R.10
Labrie, F.11
-
82
-
-
0029670229
-
Human 17b-hydroxysteroid dehydrogenase type 1 and type 2 isozymes have opposite activities in 690 cultured cells and characteristic celland tissue-specific expression
-
Miettinen MM, Mustonen MVJ, Poutanen MH, Isomaa VV and Vihko RK: Human 17b-hydroxysteroid dehydrogenase type 1 and type 2 isozymes have opposite activities in 690 cultured cells and characteristic celland tissue-specific expression. Biochem J 314: 839-845, 1996.
-
(1996)
Biochem J
, vol.314
, pp. 839-845
-
-
Miettinen, M.M.1
Mustonen, M.V.J.2
Poutanen, M.H.3
Isomaa, V.V.4
Vihko, R.K.5
-
83
-
-
0037427071
-
Amplification of HSD17B1 and ERBB2 in primary breast cancer
-
Gunnarsson C, Ahnstrom M, Kirschner K, Olsson B, Nordenskjold B, Rutqvist LE, Skoog L and Stal O: Amplification of HSD17B1 and ERBB2 in primary breast cancer. Oncogene 22: 34-40, 2003.
-
(2003)
Oncogene
, vol.22
, pp. 34-40
-
-
Gunnarsson, C.1
Ahnstrom, M.2
Kirschner, K.3
Olsson, B.4
Nordenskjold, B.5
Rutqvist, L.E.6
Skoog, L.7
Stal, O.8
-
84
-
-
0031596231
-
17Betahydroxysteroid dehydrogenase types 1 and 2 in human placenta: An immunohistochemical study with correlation to placental development
-
Takeyama J, Sasano H, Suzuki T, Iinuma K, Nagura H and Andersson S: 17Betahydroxysteroid dehydrogenase types 1 and 2 in human placenta: an immunohistochemical study with correlation to placental development. J Clinic Endocrinol Metabol 83: 3710-3715, 1998.
-
(1998)
J Clinic Endocrinol Metabol
, vol.83
, pp. 3710-3715
-
-
Takeyama, J.1
Sasano, H.2
Suzuki, T.3
Iinuma, K.4
Nagura, H.5
Andersson, S.6
-
85
-
-
0034335393
-
17beta-hydroxysteroid dehydrogenase type 1 and 2 expression in the human fetus
-
Takeyama J, Suzuki T, Hirasawa G, Muramatsu Y, Nagura H, Iinuraa K, Nakamura J, Kimura KI, Yoshihama M, Harada N, Andersson S and Sasano H: 17beta-hydroxysteroid dehydrogenase type 1 and 2 expression in the human fetus. J Clinic Endocrinol Metabol 85: 410-416, 2000.
-
(2000)
J Clinic Endocrinol Metabol
, vol.85
, pp. 410-416
-
-
Takeyama, J.1
Suzuki, T.2
Hirasawa, G.3
Muramatsu, Y.4
Nagura, H.5
Iinuraa, K.6
Nakamura, J.7
Kimura, K.I.8
Yoshihama, M.9
Harada, N.10
Andersson, S.11
Sasano, H.12
-
86
-
-
0025866941
-
Interleukin-6 is secreted by breast fibroblasts and stimulates 17 beta oxidoreductase activity in MCF-7 breast cancer cells: Possible paracrine regulation of 17beta oestradiol levels
-
Adams EF, Rafferty B and White MC: Interleukin-6 is secreted by breast fibroblasts and stimulates 17 beta oxidoreductase activity in MCF-7 breast cancer cells: possible paracrine regulation of 17beta oestradiol levels. Int J Cancer 49: 118-121, 1991.
-
(1991)
Int J Cancer
, vol.49
, pp. 118-121
-
-
Adams, E.F.1
Rafferty, B.2
White, M.C.3
-
87
-
-
0028322040
-
The interaction of cytokines in regulating oestradiol 17beta hydroxysteroid dehydrogenase activity in MCF-7 cells
-
Duncan LJ, Coldham NG and Reed MJ: The interaction of cytokines in regulating oestradiol 17beta hydroxysteroid dehydrogenase activity in MCF-7 cells. J Steroid Biochem Mol Biol 49: 63-68, 1994.
-
(1994)
J Steroid Biochem Mol Biol
, vol.49
, pp. 63-68
-
-
Duncan, L.J.1
Coldham, N.G.2
Reed, M.J.3
-
88
-
-
0026751207
-
Synergistic interaction of growth factors and albumin in regulating estrogen synthesis in breast cancer cells
-
Singh A, Blench I, Morris HR, Savoy LA and Reed MJ: Synergistic interaction of growth factors and albumin in regulating estrogen synthesis in breast cancer cells. Mol Cell Endocrinol 85: 165-173, 1992.
-
(1992)
Mol Cell Endocrinol
, vol.85
, pp. 165-173
-
-
Singh, A.1
Blench, I.2
Morris, H.R.3
Savoy, L.A.4
Reed, M.J.5
-
89
-
-
0020326596
-
Significance of aromatase activity in human breast cancer
-
Miller WR, Hawkins RA and Forrest APM: Significance of aromatase activity in human breast cancer. Cancer Res 42: 3365-3368, 1982.
-
(1982)
Cancer Res
, vol.42
, pp. 3365-3368
-
-
Miller, W.R.1
Hawkins, R.A.2
Forrest, A.P.M.3
-
90
-
-
0018893170
-
The conversion of androstenedione to estrone, estradiol and testosterone in breast tissue
-
Perel E, Wilkins D and Killinger DW: The conversion of androstenedione to estrone, estradiol and testosterone in breast tissue. J Steroid Biochem 13: 89-94, 1980.
-
(1980)
J Steroid Biochem
, vol.13
, pp. 89-94
-
-
Perel, E.1
Wilkins, D.2
Killinger, D.W.3
-
91
-
-
0034132569
-
17 Beta hydroxysteroid dehydrogenase type 1 and type 2 in human breast carcinoma: A correlation to clinicopathological parameters
-
Suzuki T, Moriya T, Ariga N, Kaneko C, Kanazawa M and Sasano H: 17 Beta hydroxysteroid dehydrogenase type 1 and type 2 in human breast carcinoma: a correlation to clinicopathological parameters. Br J Cancer 82: 518-523, 2000.
-
(2000)
Br J Cancer
, vol.82
, pp. 518-523
-
-
Suzuki, T.1
Moriya, T.2
Ariga, N.3
Kaneko, C.4
Kanazawa, M.5
Sasano, H.6
-
92
-
-
33751240474
-
Human hydroxysteroid (17-beta) dehydrogenase 1 expression enhances estrogen sensitivity of MCF-7 breast cancer cell xenografts
-
Husen B, Huhtinen K, Saloniemi T, Messinger J, Thole HH and Poutanen M: Human hydroxysteroid (17-beta) dehydrogenase 1 expression enhances estrogen sensitivity of MCF-7 breast cancer cell xenografts. Endocrinology 747: 5333-5339, 2006.
-
(2006)
Endocrinology
, vol.747
, pp. 5333-5339
-
-
Husen, B.1
Huhtinen, K.2
Saloniemi, T.3
Messinger, J.4
Thole, H.H.5
Poutanen, M.6
-
93
-
-
0029817523
-
Aromatase and 17beta hydroxysteroid dehydrogenase type 1 in human breast carcinoma
-
Sasano H, Frost AR, Saitoh R, Harada N, Poutanen M, Vihko R, Buhm SE, Silverberg SG and Nagura H: Aromatase and 17beta hydroxysteroid dehydrogenase type 1 in human breast carcinoma. J Clin Endocrinol Metab 11: 4042-4046, 1996.
-
(1996)
J Clin Endocrinol Metab
, vol.11
, pp. 4042-4046
-
-
Sasano, H.1
Frost, A.R.2
Saitoh, R.3
Harada, N.4
Poutanen, M.5
Vihko, R.6
Buhm, S.E.7
Silverberg, S.G.8
Nagura, H.9
-
94
-
-
0037939776
-
Estrogen sulfotransferase and steroid sulfatase in human breast carcinoma
-
Suzuki T, Nakata T, Miki Y, Kaneko C, Moriya T, Ishida T, Akinaga S, Hirakawa H, Kimura M and Sasano H: Estrogen sulfotransferase and steroid sulfatase in human breast carcinoma. Cancer Res 63: 2762-2770, 2003.
-
(2003)
Cancer Res
, vol.63
, pp. 2762-2770
-
-
Suzuki, T.1
Nakata, T.2
Miki, Y.3
Kaneko, C.4
Moriya, T.5
Ishida, T.6
Akinaga, S.7
Hirakawa, H.8
Kimura, M.9
Sasano, H.10
-
95
-
-
0034053341
-
17 beta-Hydroxysteroid dehydrogenase type 1 and type 2 in ductal carcinoma in situ and intraductal proliferative lesions of the human breast
-
Ariga N, Moriya T, Suzuki T, Kimura M, Ohuchi N, Satomi S and Sasano H: 17 beta-Hydroxysteroid dehydrogenase type 1 and type 2 in ductal carcinoma in situ and intraductal proliferative lesions of the human breast. Anticancer Research 20: 1101-1108, 2000.
-
(2000)
Anticancer Research
, vol.20
, pp. 1101-1108
-
-
Ariga, N.1
Moriya, T.2
Suzuki, T.3
Kimura, M.4
Ohuchi, N.5
Satomi, S.6
Sasano, H.7
-
96
-
-
5644246147
-
17beta-hydroxysteroid dehydrogenase type 1 is an independent prognostic marker in breast cancer
-
Oduwole OO, Li Y, Isomaa VV, Mantyniemi A, Pulkka AE, Soini Y and Vihko PT: 17beta-hydroxysteroid dehydrogenase type 1 is an independent prognostic marker in breast cancer. Cancer Res 64: 7604-7609, 2004.
-
(2004)
Cancer Res
, vol.64
, pp. 7604-7609
-
-
Oduwole, O.O.1
Li, Y.2
Isomaa, V.V.3
Mantyniemi, A.4
Pulkka, A.E.5
Soini, Y.6
Vihko, P.T.7
-
97
-
-
0642367430
-
Quantitative determination, by real-time reverse transcription polymerase chain reaction, of aromatase mRNA in invasive ductal carcinoma of the breast
-
Zhang Z, Yamashita H, Toyama T, Omoto Y, Sugiura H, Hara Y, Wu X, Kobayashi S and Iwase H: Quantitative determination, by real-time reverse transcription polymerase chain reaction, of aromatase mRNA in invasive ductal carcinoma of the breast. Breast Cancer Res 5: 250-256, 2003.
-
(2003)
Breast Cancer Res
, vol.5
, pp. 250-256
-
-
Zhang, Z.1
Yamashita, H.2
Toyama, T.3
Omoto, Y.4
Sugiura, H.5
Hara, Y.6
Wu, X.7
Kobayashi, S.8
Iwase, H.9
-
98
-
-
0035529054
-
Southeast Sweden Breast Cancer GroupAbnormal expression of 17beta-hydroxysteroid dehydrogenases in breast cancer predicts late recurrence
-
Gunnarsson C, Olsson BM and Stal O: Southeast Sweden Breast Cancer GroupAbnormal expression of 17beta-hydroxysteroid dehydrogenases in breast cancer predicts late recurrence. Cancer Res 61: 8448 -8451, 2001.
-
(2001)
Cancer Res
, vol.61
, pp. 8448-8451
-
-
Gunnarsson, C.1
Olsson, B.M.2
Stal, O.3
-
99
-
-
43049108105
-
Amplification of HSD17B1 has prognostic significance in postmenopausal breast cancer
-
Gunnarsson C, Jerevall PL, Hammar K, Olsson B, Nordenskjöld B, Jansson A and Stål O: Amplification of HSD17B1 has prognostic significance in postmenopausal breast cancer. Breast Cancer Res Treat 108: 35-41, 2008.
-
(2008)
Breast Cancer Res Treat
, vol.108
, pp. 35-41
-
-
Gunnarsson, C.1
Jerevall, P.L.2
Hammar, K.3
Olsson, B.4
Nordenskjöld, B.5
Jansson, A.6
Stål, O.7
-
100
-
-
0035863524
-
Building a multigenic model of breast cancer susceptibility: CYP 17 and HSD 17 beta 1 are two important candidates
-
lOO Feigelson SH, McKean-Cowdin R, Coetzee GA, Stram DO, Kolonel LN and Henderson BE: Building a multigenic model of breast cancer susceptibility: CYP 17 and HSD 17 beta 1 are two important candidates. Cancer Res 61: 785-789, 2001.
-
(2001)
Cancer Res
, vol.61
, pp. 785-789
-
-
lOO Feigelson, S.H.1
McKean-Cowdin, R.2
Coetzee, G.A.3
Stram, D.O.4
Kolonel, L.N.5
Henderson, B.E.6
-
101
-
-
24744437348
-
E-ring modified steroids as novel potent inhibitors of 17 beta-hydroxysteroid dehydrogenase type 1
-
Fischer DS, Allan GM, Bubert C, Vicker N, Smith A, Tutill HJ, Purohit A, Wood L, Packham G, Mahon MF, Reed MJ and Potter BV: E-ring modified steroids as novel potent inhibitors of 17 beta-hydroxysteroid dehydrogenase type 1. J Med Chem 48: 5749-5770, 2005.
-
(2005)
J Med Chem
, vol.48
, pp. 5749-5770
-
-
Fischer, D.S.1
Allan, G.M.2
Bubert, C.3
Vicker, N.4
Smith, A.5
Tutill, H.J.6
Purohit, A.7
Wood, L.8
Packham, G.9
Mahon, M.F.10
Reed, M.J.11
Potter, B.V.12
-
102
-
-
0031568850
-
Structure of a human lysosomal sulfatase
-
Bond CS, Clements PR, Ashby SJ, Collyer CA, Harrop SJ, Hopwood JJ and Guss JM: Structure of a human lysosomal sulfatase. Structure 5: 277-289, 1997.
-
(1997)
Structure
, vol.5
, pp. 277-289
-
-
Bond, C.S.1
Clements, P.R.2
Ashby, S.J.3
Collyer, C.A.4
Harrop, S.J.5
Hopwood, J.J.6
Guss, J.M.7
-
103
-
-
0036922691
-
Molecular and biochemical characterisation of a novel sulphatase gene: Ary1 sulphatase G (ARSG)
-
Ferrante P, Messali S, Meroni G and Ballabio A: Molecular and biochemical characterisation of a novel sulphatase gene: ary1 sulphatase G (ARSG). Eur J Hum Genet 10: 813-818, 2002.
-
(2002)
Eur J Hum Genet
, vol.10
, pp. 813-818
-
-
Ferrante, P.1
Messali, S.2
Meroni, G.3
Ballabio, A.4
-
104
-
-
0024208474
-
The human X-linked steroid sulfatase gene and a Y-encoded pseudogene: Evidence for an inversion of the Y chromosome during primate evolution
-
Yen PH, Marsh B, Allen E, Tsai SP, Ellison J, Connoly L, Neiswanger K and Shapiro LJ: The human X-linked steroid sulfatase gene and a Y-encoded pseudogene: evidence for an inversion of the Y chromosome during primate evolution. Cell 55: 1123-1135, 1988.
-
(1988)
Cell
, vol.55
, pp. 1123-1135
-
-
Yen, P.H.1
Marsh, B.2
Allen, E.3
Tsai, S.P.4
Ellison, J.5
Connoly, L.6
Neiswanger, K.7
Shapiro, L.J.8
-
105
-
-
17044428337
-
Steroid sulfatase: Molecular biology, regulation, and inhibition
-
Reed MJ, Purohit A, Woo LW, Newman SP and Potter BV: Steroid sulfatase: molecular biology, regulation, and inhibition. Endocr Rev 26: 171-202, 2005.
-
(2005)
Endocr Rev
, vol.26
, pp. 171-202
-
-
Reed, M.J.1
Purohit, A.2
Woo, L.W.3
Newman, S.P.4
Potter, B.V.5
-
106
-
-
0026555455
-
Oestrogen sulphatase activity in hormone-dependent and hormone-independent breast cancer cells: Modulation by steroidal and non760 steroidal therapeutic agents
-
Purohit A and Reed MJ: Oestrogen sulphatase activity in hormone-dependent and hormone-independent breast cancer cells: modulation by steroidal and non760 steroidal therapeutic agents. Int J Cancer 50: 901-905, 1992.
-
(1992)
Int J Cancer
, vol.50
, pp. 901-905
-
-
Purohit, A.1
Reed, M.J.2
-
107
-
-
0034739787
-
Regulation of steroid sulphatase expression and activity in breast cancer
-
Newman SP, Purohit A, Ghilchik MW, Potter BVL and Reed MJ: Regulation of steroid sulphatase expression and activity in breast cancer. J Steroid Biochem Mol Biol 75: 259-264, 2000.
-
(2000)
J Steroid Biochem Mol Biol
, vol.75
, pp. 259-264
-
-
Newman, S.P.1
Purohit, A.2
Ghilchik, M.W.3
Potter, B.V.L.4
Reed, M.J.5
-
108
-
-
0028061872
-
Effect of the progestagen Promegestone (R-5020) on mRNA of the oestrone sulphatase in the MCF-7 human mammary cancer cells
-
Pasqualini JR, Maloche C, Maroni M and Chetrite G: Effect of the progestagen Promegestone (R-5020) on mRNA of the oestrone sulphatase in the MCF-7 human mammary cancer cells. Anticancer Res 14: 1589-1594, 1994.
-
(1994)
Anticancer Res
, vol.14
, pp. 1589-1594
-
-
Pasqualini, J.R.1
Maloche, C.2
Maroni, M.3
Chetrite, G.4
-
110
-
-
0027155267
-
Control of aromatase activity in breast cancer cells: The role of cytokines and growth factors
-
Reed MJ, Topping L, Coldham NG, Purohit A, Ghilchik MW and James VHT: Control of aromatase activity in breast cancer cells: the role of cytokines and growth factors. J Steroid Biochem Molec Biol 44: 589-596, 1993.
-
(1993)
J Steroid Biochem Molec Biol
, vol.44
, pp. 589-596
-
-
Reed, M.J.1
Topping, L.2
Coldham, N.G.3
Purohit, A.4
Ghilchik, M.W.5
James, V.H.T.6
-
111
-
-
0010595026
-
Inhibition of steroid sulphatases
-
Sandler M, Smith HJ eds, Oxford: Oxford University Press, pp
-
Reed MJ and Purohit A: Inhibition of steroid sulphatases. In: Sandler M, Smith HJ (eds.). Design of enzyme inhibitors as drugs, vol. 2. Oxford: Oxford University Press, pp. 481-494, 1994.
-
(1994)
Design of enzyme inhibitors as drugs
, vol.2
, pp. 481-494
-
-
Reed, M.J.1
Purohit, A.2
-
112
-
-
0026550483
-
Identification of point mutations in the steroid sulfatase gene of three patients with X-linked ichthyosis
-
Basler E, Grompe M, Parenti G, Yates J and Ballabio A: Identification of point mutations in the steroid sulfatase gene of three patients with X-linked ichthyosis. Am J Hum Genet 50: 483-491, 1992.
-
(1992)
Am J Hum Genet
, vol.50
, pp. 483-491
-
-
Basler, E.1
Grompe, M.2
Parenti, G.3
Yates, J.4
Ballabio, A.5
-
113
-
-
0030753202
-
Characterization of point mutations in patients with Xlinked ichthyosis. Effects on the structure and function of the steroid sulfatase protein
-
Alperin ES and Shapiro LJ: Characterization of point mutations in patients with Xlinked ichthyosis. Effects on the structure and function of the steroid sulfatase protein. J Biol Chem 272: 20756-20763, 1997.
-
(1997)
J Biol Chem
, vol.272
, pp. 20756-20763
-
-
Alperin, E.S.1
Shapiro, L.J.2
-
114
-
-
0001081682
-
In: Adrenal androgen secretion and metabolism in postmenopausal women
-
Genazzani AR, Thijssen JHH, Siiteri PK eds, New York: Raven Press, pp
-
Poortman J, Andriesse R, Agema A, Douker GH, Schwarz F and Thijssen JHH: In: Adrenal androgen secretion and metabolism in postmenopausal women. Genazzani AR, Thijssen JHH, Siiteri PK (eds.). Adrenal androgens. New York: Raven Press, pp. 219-240, 1980.
-
(1980)
Adrenal androgens
, pp. 219-240
-
-
Poortman, J.1
Andriesse, R.2
Agema, A.3
Douker, G.H.4
Schwarz, F.5
Thijssen, J.H.H.6
-
115
-
-
0022536513
-
Stimulation of cell proliferation and estrogenic response by adrenal C19- delta 5-steroids in the ZR-75-1 human breast cancer cell line
-
Poulin R and Labrie F: Stimulation of cell proliferation and estrogenic response by adrenal C19- delta 5-steroids in the ZR-75-1 human breast cancer cell line. Cancer Res 46: 4933-4937, 1986.
-
(1986)
Cancer Res
, vol.46
, pp. 4933-4937
-
-
Poulin, R.1
Labrie, F.2
-
116
-
-
0033214658
-
Adrenal androgens stimulate the proliferation of breast cancer cells as direct activators of estrogen receptor alpha
-
Maggiolini M, Donze O, Jeannin E, Ando S and Picard D: Adrenal androgens stimulate the proliferation of breast cancer cells as direct activators of estrogen receptor alpha. Cancer Res 59: 4864-4869, 1999.
-
(1999)
Cancer Res
, vol.59
, pp. 4864-4869
-
-
Maggiolini, M.1
Donze, O.2
Jeannin, E.3
Ando, S.4
Picard, D.5
-
117
-
-
0035666689
-
High dehydroepiandrosterone-sulfate predicts breast cancer progression during new aromatase inhibitor therapy and stimulates breast cancer cell growth in tissue culture: A renewed role for adrenalectomy
-
Morris KT, Toth-Fejel SE, Schmidt J, Fletcher WS and Pommier RF: High dehydroepiandrosterone-sulfate predicts breast cancer progression during new aromatase inhibitor therapy and stimulates breast cancer cell growth in tissue culture: a renewed role for adrenalectomy. Surgery 130: 947-953, 2001.
-
(2001)
Surgery
, vol.130
, pp. 947-953
-
-
Morris, K.T.1
Toth-Fejel, S.E.2
Schmidt, J.3
Fletcher, W.S.4
Pommier, R.F.5
-
118
-
-
0034210051
-
Elevated steroid sulfatase expression in breast cancer
-
Utsumi T, Yoshimura N, Takeuchi S, Maruta M, Maeda K and Harada N: Elevated steroid sulfatase expression in breast cancer. J Steroid Biochem Mol Biol 73: 141-145, 2000.
-
(2000)
J Steroid Biochem Mol Biol
, vol.73
, pp. 141-145
-
-
Utsumi, T.1
Yoshimura, N.2
Takeuchi, S.3
Maruta, M.4
Maeda, K.5
Harada, N.6
-
119
-
-
0028328913
-
Intratumoral oestrone sulphatase activity as a prognostic marker in human breast carcinoma
-
Evans TR, Rowlands MG, Law M and Coombes RC: Intratumoral oestrone sulphatase activity as a prognostic marker in human breast carcinoma. Br J Cancer 69: 555-561, 1994.
-
(1994)
Br J Cancer
, vol.69
, pp. 555-561
-
-
Evans, T.R.1
Rowlands, M.G.2
Law, M.3
Coombes, R.C.4
-
120
-
-
0033555597
-
Steroid sulfatase expression is an independent predictor of recurrence in human breast cancer
-
Utsumi T, Yoshimura N, Takeuchi S, Ando J, Maruta M, Maeda K and Harada N: Steroid sulfatase expression is an independent predictor of recurrence in human breast cancer. Cancer Res 59: 377-381, 1999.
-
(1999)
Cancer Res
, vol.59
, pp. 377-381
-
-
Utsumi, T.1
Yoshimura, N.2
Takeuchi, S.3
Ando, J.4
Maruta, M.5
Maeda, K.6
Harada, N.7
-
121
-
-
33845942044
-
The Role of STS and OATP-B mRNA Expression in Predicting the Clinical Outcome in Human Breast Cancer
-
Al Sarakbi W, Mokbel R, Salhab M, Jiang WG, Reed MJ and Mokbel K: The Role of STS and OATP-B mRNA Expression in Predicting the Clinical Outcome in Human Breast Cancer. Anticancer Res 26: 4985-4990, 2006.
-
(2006)
Anticancer Res
, vol.26
, pp. 4985-4990
-
-
Al Sarakbi, W.1
Mokbel, R.2
Salhab, M.3
Jiang, W.G.4
Reed, M.J.5
Mokbel, K.6
-
122
-
-
10744226017
-
Role of steroid sulfatase in local formation of estrogen in postmenopausal breast cancer patients
-
Nakata T, Takashima S, Shiotsu Y, Murakata C, Ishida H, Akinaga S, Li PK, Sasano H, Suzuki T and Saeki T: Role of steroid sulfatase in local formation of estrogen in postmenopausal breast cancer patients. J Steroid Biochem Mol Biol 86: 455-460, 2003.
-
(2003)
J Steroid Biochem Mol Biol
, vol.86
, pp. 455-460
-
-
Nakata, T.1
Takashima, S.2
Shiotsu, Y.3
Murakata, C.4
Ishida, H.5
Akinaga, S.6
Li, P.K.7
Sasano, H.8
Suzuki, T.9
Saeki, T.10
-
123
-
-
0031045478
-
Inhibition of estrone sulfatase and proliferation of human breast cancer cells by nonsteroidal (p-O-sulfamoyl)-N- alkanoyl tyramines
-
Selcer KW, Hegde PV and Li PK: Inhibition of estrone sulfatase and proliferation of human breast cancer cells by nonsteroidal (p-O-sulfamoyl)-N- alkanoyl tyramines. Cancer Res 57: 702-707, 1997.
-
(1997)
Cancer Res
, vol.57
, pp. 702-707
-
-
Selcer, K.W.1
Hegde, P.V.2
Li, P.K.3
-
124
-
-
0034234951
-
In vivo inhibition of estrone sulfatase activity and growth of nitrosomethylurea-induced mammary tumors by 667 COUMATE
-
Purohit A, Woo LWL, Potter BVL and Reed MJ: In vivo inhibition of estrone sulfatase activity and growth of nitrosomethylurea-induced mammary tumors by 667 COUMATE. Cancer Res 60: 3394-3396, 2000.
-
(2000)
Cancer Res
, vol.60
, pp. 3394-3396
-
-
Purohit, A.1
Woo, L.W.L.2
Potter, B.V.L.3
Reed, M.J.4
-
125
-
-
0242500489
-
-
Fischer DS, Chander SK, Woo, Fenton JC, Purohit A, Reed MJ and Potter BV: Novel D-ring modified steroid derivatives as potent, non-estrogenic steroid sulfatase inhibitors with in vivo activity. J Steroid Biochem Mol 84: 343-349, 2003.
-
Fischer DS, Chander SK, Woo, Fenton JC, Purohit A, Reed MJ and Potter BV: Novel D-ring modified steroid derivatives as potent, non-estrogenic steroid sulfatase inhibitors with in vivo activity. J Steroid Biochem Mol 84: 343-349, 2003.
-
-
-
-
126
-
-
33749331848
-
In vivo efficacy of STX213, a second-generation steroid sulfatase inhibitor, for hormone-dependent breast cancer therapy
-
Foster PA, Newman SP, Chander SK, Stengel C, Jhalli R, Woo LWL, Potter BVL, Reed MJ and Purohit A: In vivo efficacy of STX213, a second-generation steroid sulfatase inhibitor, for hormone-dependent breast cancer therapy. Clin Cancer Res 12: 5543-5549, 2006.
-
(2006)
Clin Cancer Res
, vol.12
, pp. 5543-5549
-
-
Foster, P.A.1
Newman, S.P.2
Chander, S.K.3
Stengel, C.4
Jhalli, R.5
Woo, L.W.L.6
Potter, B.V.L.7
Reed, M.J.8
Purohit, A.9
-
127
-
-
0037904915
-
Inhibition of carbonic anhydrase II by steroidal and nonsteroidal sulphamates
-
Ho YT, Purohit A, Vicker N, Newman SP, Robinson JJ, Leese MP, Ganeshapillai D, Woo LWL, Potter BVL and Reed MJ: Inhibition of carbonic anhydrase II by steroidal and nonsteroidal sulphamates. Biochem Biophys Res Commun 305: 909-914, 2003.
-
(2003)
Biochem Biophys Res Commun
, vol.305
, pp. 909-914
-
-
Ho, Y.T.1
Purohit, A.2
Vicker, N.3
Newman, S.P.4
Robinson, J.J.5
Leese, M.P.6
Ganeshapillai, D.7
Woo, L.W.L.8
Potter, B.V.L.9
Reed, M.J.10
-
128
-
-
33645082465
-
Phase I study of STX 64 (667 Coumate) in breast cancer patients: The first study of a steroid sulfatase inhibitor
-
Stanway SJ, Purohit A, Woo LWL, Sufi S, Vigushin D, Ward R, Wilson RH, Stanczyk FZ, Dobbs N, Kulinskaya E, Elliott M, Potter BVL, Reed MJ and Coombes RC: Phase I study of STX 64 (667 Coumate) in breast cancer patients: The first study of a steroid sulfatase inhibitor. Clin Cancer Res 12: 1585-1592, 2006.
-
(2006)
Clin Cancer Res
, vol.12
, pp. 1585-1592
-
-
Stanway, S.J.1
Purohit, A.2
Woo, L.W.L.3
Sufi, S.4
Vigushin, D.5
Ward, R.6
Wilson, R.H.7
Stanczyk, F.Z.8
Dobbs, N.9
Kulinskaya, E.10
Elliott, M.11
Potter, B.V.L.12
Reed, M.J.13
Coombes, R.C.14
-
129
-
-
34547595440
-
Dual Aromatase-Steroid Sulfatase Inhibitors
-
Woo LW, Bubert C, Sutcliffe OB, Smith A, Chander SK, Mahon MF, Purohit A, Reed MJ and Potter BV: Dual Aromatase-Steroid Sulfatase Inhibitors. J Med Chem 26: 3540-60, 2007.
-
(2007)
J Med Chem
, vol.26
, pp. 3540-3560
-
-
Woo, L.W.1
Bubert, C.2
Sutcliffe, O.B.3
Smith, A.4
Chander, S.K.5
Mahon, M.F.6
Purohit, A.7
Reed, M.J.8
Potter, B.V.9
-
130
-
-
18144391164
-
A letrozole-based dual aromatase-sulphatase inhibitor with in vivo activity
-
Wood PM, Woo LW, Humphreys A, Chander SK, Purohit A, Reed MJ and Potter BV: A letrozole-based dual aromatase-sulphatase inhibitor with in vivo activity. J Steroid Biochem Mol Biol 94: 123-130, 2005.
-
(2005)
J Steroid Biochem Mol Biol
, vol.94
, pp. 123-130
-
-
Wood, P.M.1
Woo, L.W.2
Humphreys, A.3
Chander, S.K.4
Purohit, A.5
Reed, M.J.6
Potter, B.V.7
-
131
-
-
0031593569
-
Expression of 3beta-hydroxysteroid dehydrogenase-5,4-en isomerase activity by infiltrating ductal human breast carcinoma in vitro
-
Gunasegaram R, Peh KL, Loganath A and Ratnam SS: Expression of 3beta-hydroxysteroid dehydrogenase-5,4-en isomerase activity by infiltrating ductal human breast carcinoma in vitro. Breast Cancer Res Treat 50: 117-123, 1998.
-
(1998)
Breast Cancer Res Treat
, vol.50
, pp. 117-123
-
-
Gunasegaram, R.1
Peh, K.L.2
Loganath, A.3
Ratnam, S.S.4
-
132
-
-
0028302746
-
Immunolocalization of aromatase and other steroidogenic enzymes in human breast disorders
-
Sasano H, Nagura H, Harada N, Goukon Y and Kimura M: Immunolocalization of aromatase and other steroidogenic enzymes in human breast disorders. Human Pathology 5: 530-533, 1994.
-
(1994)
Human Pathology
, vol.5
, pp. 530-533
-
-
Sasano, H.1
Nagura, H.2
Harada, N.3
Goukon, Y.4
Kimura, M.5
-
133
-
-
0027461214
-
Regulation of 3beta-hydroxysteroid dehydrogenase and 17betahydroxysteroid dehydrogenase messenger ribonucleic acid levels by cyclic adenosine 30 ,50-monophosphate and phorbol myristate acetate in human choriocarcinoma cells
-
Tremblay Y and Beaudoin C: Regulation of 3beta-hydroxysteroid dehydrogenase and 17betahydroxysteroid dehydrogenase messenger ribonucleic acid levels by cyclic adenosine 30 ,50-monophosphate and phorbol myristate acetate in human choriocarcinoma cells. J Mol Endocrinol 7: 355-364, 1993.
-
(1993)
J Mol Endocrinol
, vol.7
, pp. 355-364
-
-
Tremblay, Y.1
Beaudoin, C.2
-
134
-
-
0032615619
-
Induction of 3beta-hydroxysteroid dehydrogenase/delta5-delta4 isomerase type 1 gene transcription in human breast cancer cell lines and in normal mammary epithelial cells by interleukin-4 and interleukin-13
-
Gingras S, Moriggl R, Groner B and Simard J: Induction of 3beta-hydroxysteroid dehydrogenase/delta5-delta4 isomerase type 1 gene transcription in human breast cancer cell lines and in normal mammary epithelial cells by interleukin-4 and interleukin-13. J Mol Endocrinol 13: 66-81, 1999.
-
(1999)
J Mol Endocrinol
, vol.13
, pp. 66-81
-
-
Gingras, S.1
Moriggl, R.2
Groner, B.3
Simard, J.4
-
135
-
-
0034456023
-
Multiple signaling pathways mediate interleukin-4-induced 3betahydroxysteroid dehydro-genase/delta5-delta4 isomerase type 1 gene expression in human breast cancer cells
-
Gingras S, Cote S and Simard J: Multiple signaling pathways mediate interleukin-4-induced 3betahydroxysteroid dehydro-genase/delta5-delta4 isomerase type 1 gene expression in human breast cancer cells. J Mol Endocrinol 14: 229-240, 2000.
-
(2000)
J Mol Endocrinol
, vol.14
, pp. 229-240
-
-
Gingras, S.1
Cote, S.2
Simard, J.3
-
136
-
-
0028359554
-
Human liver estrogen sulfotransferase: Identification by cDNA cloning and expression
-
Aksoy IA, Wood TC and Weinshilboum R: Human liver estrogen sulfotransferase: identification by cDNA cloning and expression. Biochem Biophys Res Commun 200: 1621-1629, 1994.
-
(1994)
Biochem Biophys Res Commun
, vol.200
, pp. 1621-1629
-
-
Aksoy, I.A.1
Wood, T.C.2
Weinshilboum, R.3
-
137
-
-
0029053067
-
Bacterial expression and characterization of a cDNA for human liver estrogen sulfotransferase
-
Falany CN, Krasnykh V and Falany JL: Bacterial expression and characterization of a cDNA for human liver estrogen sulfotransferase. J Steroid Biochem Mol Biol 52: 529-539, 1995.
-
(1995)
J Steroid Biochem Mol Biol
, vol.52
, pp. 529-539
-
-
Falany, C.N.1
Krasnykh, V.2
Falany, J.L.3
-
138
-
-
0029916538
-
Expression of cytosolic sulfotransferases in normal mammary epithelial cells and breast cancer cell lines
-
Falany JL and Falany CN: Expression of cytosolic sulfotransferases in normal mammary epithelial cells and breast cancer cell lines. Cancer Research 56: 1551-1555, 1996.
-
(1996)
Cancer Research
, vol.56
, pp. 1551-1555
-
-
Falany, J.L.1
Falany, C.N.2
-
139
-
-
0031759925
-
Human estrogen sulfotransferase (hESTl) activities and its mRNA in various breast cancer cell lines. Effect of the progestin, promegestone (R-5020)
-
Chetrite G, Le Nestour E and Pasqualini JR: Human estrogen sulfotransferase (hESTl) activities and its mRNA in various breast cancer cell lines. Effect of the progestin, promegestone (R-5020). J Steroid Biochem Mol Biol 66: 295-302, 1998.
-
(1998)
J Steroid Biochem Mol Biol
, vol.66
, pp. 295-302
-
-
Chetrite, G.1
Le Nestour, E.2
Pasqualini, J.R.3
-
140
-
-
0018654197
-
A correlation between estrogen sulfotransferase levels and estrogen receptor status in human primary breast carcinoma
-
Adams JB, Pewnim T, Chandra DP, Archibald L and Foo MS: A correlation between estrogen sulfotransferase levels and estrogen receptor status in human primary breast carcinoma. Cancer Research 39: 5124-5126,1979.
-
(1979)
Cancer Research
, vol.39
, pp. 5124-5126
-
-
Adams, J.B.1
Pewnim, T.2
Chandra, D.P.3
Archibald, L.4
Foo, M.S.5
-
141
-
-
0021020861
-
Estrogen sulfatase and estrogen sulfotransferase in human primary mammary carcinoma
-
Tseng L, Mazella J, Lee LY and Stone ML: Estrogen sulfatase and estrogen sulfotransferase in human primary mammary carcinoma. J Steroid Biochem 4: 1413-1417, 1983.
-
(1983)
J Steroid Biochem
, vol.4
, pp. 1413-1417
-
-
Tseng, L.1
Mazella, J.2
Lee, L.Y.3
Stone, M.L.4
-
142
-
-
0029872530
-
Concentrations of estrone, estradiol, and estrone sulfate and evaluation of sulfatase and aromatase activities in pre- and post-menopausal breast cancer patients
-
Pasqualini JR, Chetrite G, Blacker C, Feinstein MC, Delalonde L, Talbi M and Maloche C: Concentrations of estrone, estradiol, and estrone sulfate and evaluation of sulfatase and aromatase activities in pre- and post-menopausal breast cancer patients. J Clin Endocrinol Metab 81: 1460-1464, 1996.
-
(1996)
J Clin Endocrinol Metab
, vol.81
, pp. 1460-1464
-
-
Pasqualini, J.R.1
Chetrite, G.2
Blacker, C.3
Feinstein, M.C.4
Delalonde, L.5
Talbi, M.6
Maloche, C.7
-
143
-
-
0029834242
-
Expression of cytochromes P450 in human breast tissue and tumors
-
Huang Z, Fasco MJ, Figge HL, Keyomarsi K and Kaminsky S: Expression of cytochromes P450 in human breast tissue and tumors. Drug Metab Dispos 24: 899-905, 1996.
-
(1996)
Drug Metab Dispos
, vol.24
, pp. 899-905
-
-
Huang, Z.1
Fasco, M.J.2
Figge, H.L.3
Keyomarsi, K.4
Kaminsky, S.5
-
144
-
-
0035198175
-
The expression of cytochrome P450 enzymes in human breast tumours and normal breast tissue
-
Iscan M, Klaavuniemi T, Coban T, Kapucuoglu N, Pelkonen O and Raunio H: The expression of cytochrome P450 enzymes in human breast tumours and normal breast tissue. Breast Cancer Res and Treat 70: 47-54, 2001.
-
(2001)
Breast Cancer Res and Treat
, vol.70
, pp. 47-54
-
-
Iscan, M.1
Klaavuniemi, T.2
Coban, T.3
Kapucuoglu, N.4
Pelkonen, O.5
Raunio, H.6
-
145
-
-
0031792505
-
Characterization of cytochrome P450 enzymes in human breast tissue from reduction mammaplasties
-
Hellmold H, Rylander T, Magnusson M, Reihner E, Warner M and Gustafsson JA: Characterization of cytochrome P450 enzymes in human breast tissue from reduction mammaplasties. J Clin Endocrinol Metab 83: 886-895, 1998.
-
(1998)
J Clin Endocrinol Metab
, vol.83
, pp. 886-895
-
-
Hellmold, H.1
Rylander, T.2
Magnusson, M.3
Reihner, E.4
Warner, M.5
Gustafsson, J.A.6
-
146
-
-
0037652178
-
Cytochrome p450 and glutathione transferase expression in human breast cancer
-
El-Rayes BF, Ali S, Heilbrun LK, Lababidi S, Bouwman D, Visscher D and Philip PA: Cytochrome p450 and glutathione transferase expression in human breast cancer. Clin Cancer Res 9: 705-709, 2003.
-
(2003)
Clin Cancer Res
, vol.9
, pp. 705-709
-
-
El-Rayes, B.F.1
Ali, S.2
Heilbrun, L.K.3
Lababidi, S.4
Bouwman, D.5
Visscher, D.6
Philip, P.A.7
-
147
-
-
0346244028
-
A potential role for the estrogen-metabolizing cytochrome P450 enzymes in human breast carcinogenesis
-
Modugno F, Knoll C, Kanbour-Shakir A and Romkes M: A potential role for the estrogen-metabolizing cytochrome P450 enzymes in human breast carcinogenesis. Breast Cancer Res Treat 82: 191-197, 2003.
-
(2003)
Breast Cancer Res Treat
, vol.82
, pp. 191-197
-
-
Modugno, F.1
Knoll, C.2
Kanbour-Shakir, A.3
Romkes, M.4
-
148
-
-
0032744286
-
Immunohistochemical localization of cytochrome P450 CYP1B1 in breast cancer with monoclonal antibodies specific for CYP1B1
-
McFadyen MC, Breeman S, Payne S, Stirk C, Miller ID, Melvin WT and Murray GI: Immunohistochemical localization of cytochrome P450 CYP1B1 in breast cancer with monoclonal antibodies specific for CYP1B1. J Histochem Cytochem 47: 1457-1464, 1999.
-
(1999)
J Histochem Cytochem
, vol.47
, pp. 1457-1464
-
-
McFadyen, M.C.1
Breeman, S.2
Payne, S.3
Stirk, C.4
Miller, I.D.5
Melvin, W.T.6
Murray, G.I.7
-
149
-
-
29144440747
-
-
0yama T, Morita M, Isse T, Kagawa N, Nakata S, So T, Mizukami M, Ichiki Y, Ono K, Sugaya M, Uramoto H, Yoshimatsu T, Hanagiri T, Sugio K, Kawamoto T and Yasumoto K: Immunohistochemical evaluation of cytochrome P450 (CYP) and p53 in breast cancer. Front Biosci 10: 1156-1161, 2005.
-
0yama T, Morita M, Isse T, Kagawa N, Nakata S, So T, Mizukami M, Ichiki Y, Ono K, Sugaya M, Uramoto H, Yoshimatsu T, Hanagiri T, Sugio K, Kawamoto T and Yasumoto K: Immunohistochemical evaluation of cytochrome P450 (CYP) and p53 in breast cancer. Front Biosci 10: 1156-1161, 2005.
-
-
-
-
150
-
-
0034463957
-
Is estradiol a genotoxic mutagenic carcinogen?
-
Liehr JG: Is estradiol a genotoxic mutagenic carcinogen? Endocrine Reviews 21: 40-54, 2000.
-
(2000)
Endocrine Reviews
, vol.21
, pp. 40-54
-
-
Liehr, J.G.1
-
151
-
-
0031841053
-
C16 and C17 derivatives of estradiol as inhibitors of 17β-hydroxysteroid dehydrogenase type 1: Chemical synthesis and structure-activity relationships
-
Sam KM, Boivin, RP, Tremblay MR, Auger S and Poirier D: C16 and C17 derivatives of estradiol as inhibitors of 17β-hydroxysteroid dehydrogenase type 1: Chemical synthesis and structure-activity relationships. Drug Des and Discov 15: 157-180, 1998.
-
(1998)
Drug Des and Discov
, vol.15
, pp. 157-180
-
-
Sam, K.M.1
Boivin, R.P.2
Tremblay, M.R.3
Auger, S.4
Poirier, D.5
-
153
-
-
33845336541
-
Luu-The and Poirier D: C6-(N,N-butyl-methyl-heptanamide) derivatives of estrone and estradiol as inhibitors of type 1 17β-hydroxysteroid dehydrogenase: Chemical synthesis and biological evaluation
-
Cadot, C, Laplante, Y, Kamal, F, Luu-The and Poirier D: C6-(N,N-butyl-methyl-heptanamide) derivatives of estrone and estradiol as inhibitors of type 1 17β-hydroxysteroid dehydrogenase: Chemical synthesis and biological evaluation. Bioorg Med Chem 15: 714-726, 2007.
-
(2007)
Bioorg Med Chem
, vol.15
, pp. 714-726
-
-
Cadot, C.1
Laplante, Y.2
Kamal, F.3
-
154
-
-
42249099968
-
Novel inhibitors of 17β-hydroxysteroid dehydrogenase type 1: Templates for design
-
Allan GM, Vicker N, Lawrence HR, Tutill HJ, Day JM, Huchet M, Ferrandis E, Reed MJ, Purohit A and Barry Potter VL: Novel inhibitors of 17β-hydroxysteroid dehydrogenase type 1: Templates for design. Bioorg Med Chem 16: 4438-4456, 2008.
-
(2008)
Bioorg Med Chem
, vol.16
, pp. 4438-4456
-
-
Allan, G.M.1
Vicker, N.2
Lawrence, H.R.3
Tutill, H.J.4
Day, J.M.5
Huchet, M.6
Ferrandis, E.7
Reed, M.J.8
Purohit, A.9
Barry Potter, V.L.10
-
155
-
-
10744224981
-
Steroid sulphatase inhibitors for breast cancer therapy
-
Purohit A, Woo LW, Chander SK, Newman SP, Ireson C, Ho Y, Grasso A, Leese MP, Potter BV and Reed MJ: Steroid sulphatase inhibitors for breast cancer therapy. J Steroid Biochem Mol Biol 86: 423-432, 2003.
-
(2003)
J Steroid Biochem Mol Biol
, vol.86
, pp. 423-432
-
-
Purohit, A.1
Woo, L.W.2
Chander, S.K.3
Newman, S.P.4
Ireson, C.5
Ho, Y.6
Grasso, A.7
Leese, M.P.8
Potter, B.V.9
Reed, M.J.10
-
156
-
-
34548327156
-
Dual aromatase-sulfatase inhibitors based on the anastrozole template: Synthesis, in vitro SAR, molecular modelling and in vivo activity
-
Jackson T, Woo LW, Trusselle MN, Chander SK, Purohit A, Reed MJ and Potter BV: Dual aromatase-sulfatase inhibitors based on the anastrozole template: synthesis, in vitro SAR, molecular modelling and in vivo activity. Org Biomol Chem 5: 2940-2952, 2007.
-
(2007)
Org Biomol Chem
, vol.5
, pp. 2940-2952
-
-
Jackson, T.1
Woo, L.W.2
Trusselle, M.N.3
Chander, S.K.4
Purohit, A.5
Reed, M.J.6
Potter, B.V.7
-
157
-
-
47749151848
-
Chiral aromatase and dual aromatase-steroid sulfatase inhibitors from the letrozole template: Synthesis, absolute configuration, and in vitro activity
-
Wood PM, Woo LWL, Labrosse JR, Trusselle MN, Abbate S, Longhi G, Ettore Castiglioni, Lebon F, Purohit A, Reed MJ and Potter BV: Chiral aromatase and dual aromatase-steroid sulfatase inhibitors from the letrozole template: synthesis, absolute configuration, and in vitro activity. J Med Chem 51: 4226-4238, 2008.
-
(2008)
J Med Chem
, vol.51
, pp. 4226-4238
-
-
Wood, P.M.1
Woo, L.W.L.2
Labrosse, J.R.3
Trusselle, M.N.4
Abbate, S.5
Longhi, G.6
Castiglioni, E.7
Lebon, F.8
Purohit, A.9
Reed, M.J.10
Potter, B.V.11
-
158
-
-
11244349925
-
The higher affinity of human type 1 3beta-hydroxysteroid dehydrogenase (3beta-HSDl) for substrate and inhibitor steroids relative to human 3beta-HSD2 is validated in MCF-7 tumor cells and related to subunit interactions
-
Thomas JL, Umland TC, Scaccia LA, Boswell EL and Kacsoh B: The higher affinity of human type 1 3beta-hydroxysteroid dehydrogenase (3beta-HSDl) for substrate and inhibitor steroids relative to human 3beta-HSD2 is validated in MCF-7 tumor cells and related to subunit interactions. Endocr Res 30: 935-941, 2004.
-
(2004)
Endocr Res
, vol.30
, pp. 935-941
-
-
Thomas, J.L.1
Umland, T.C.2
Scaccia, L.A.3
Boswell, E.L.4
Kacsoh, B.5
-
159
-
-
49449115829
-
Sulfotransferase 2Blb in human breast: Differences in subcellular localization in African American and Caucasian women
-
Dumas NA, He D, Frost AR and Falany CN: Sulfotransferase 2Blb in human breast: Differences in subcellular localization in African American and Caucasian women. J Steroid Biochem Mol Biol 111: 171-177, 2008.
-
(2008)
J Steroid Biochem Mol Biol
, vol.111
, pp. 171-177
-
-
Dumas, N.A.1
He, D.2
Frost, A.R.3
Falany, C.N.4
-
160
-
-
34248208754
-
Genetic variants of CYP3A5, CYP2D6, SULT1A1, UGT2B15 and tamoxifen response in postmenopausal patients with breast cancer
-
Wegman P, Elingarami S, Carstensen J, Stål O, Nordenskjöld B and Wingren S: Genetic variants of CYP3A5, CYP2D6, SULT1A1, UGT2B15 and tamoxifen response in postmenopausal patients with breast cancer. Breast Cancer Res 9: 7, 2007.
-
(2007)
Breast Cancer Res
, vol.9
, pp. 7
-
-
Wegman, P.1
Elingarami, S.2
Carstensen, J.3
Stål, O.4
Nordenskjöld, B.5
Wingren, S.6
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