Environmental estrogen stimulation of growth and estrogen receptor function in preneoplastic and cancerous human breast cell lines

Journal of the National Cancer Institute

Volumn 89, Issue 23, 1997, Pages 1774-1782

  Shekhar, P V M ^a,b   Werdell, J ^b   Basrur, V S ^b  

^a WAYNE STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b KARMANOS CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AROCLOR 1254; CHLORPHENOTANE; ESTRADIOL; ESTROGEN; ESTROGEN RECEPTOR; FULVESTRANT; HEPTACHLOR; ORGANOCHLORINE DERIVATIVE; POLYCHLORINATED BIPHENYL;

ANCHORAGE INDEPENDENT GROWTH; ARTICLE; BREAST CANCER; CANCER CELL CULTURE; CONTROLLED STUDY; ESTROGEN ACTIVITY; GENE EXPRESSION; HUMAN; HUMAN CELL; PRECANCER; RECEPTOR BINDING; REPORTER GENE;

EID: 0030692641     PISSN: 00278874     EISSN: None     Source Type: Journal    
DOI: 10.1093/jnci/89.23.1774     Document Type: Article

References (64)

1. Hunter DJ, Kelsey KT. Pesticide residues and breast cancer: the harvest of a silent spring? [editorial]. J Natl Cancer Inst 1993;85:598-9.
2. Colborn T, Vom Saal FS, Soto AM. Developmental effects of endocrinedisrupting chemicals in wildlife and humans. Environ Health Perspect 1993;101:378-84.
3. Rennie J. Malignant mimicry. False estrogens may cause cancer and lower sperm counts [news]. Sci Am 1993;269:34.
4. Sharpe RM, Skakkebaek NE. Are oestrogens involved in falling sperm counts and disorders of the male reproductive tract? Lancet 1993;341: 1392-5.
5. Sumpter JP, Jobling S. Male sexual development in "a sea of oestrogen" [letter]. Lancet 1993;342:124-5.
6. Davis DL, Bradlow HL, Wolff M, Woodruff T, Hoel DG, Anton-Culver H. Medical hypothesis: xenoestrogens as preventable causes of breast cancer. Environ Health Perspect 1993;101:372-7.
7. Stone R. Environmental estrogens stir debate. Science 1994;265:308-10.
8. Safe SH. Dietary and environmental estrogens and antiestrogens and their possible role in human disease. Environ Sci Pollut Res 1994;1:29-33.
9. Fagin D. Estrogen link. Newsday 1994 (28 Dec), A7-A9.
10. Safe SH. Environmental and dietary estrogens and human health: is there a problem? Environ Health Perspect 1995;103:346-51.
11. Davidson NE, Lippman ME. The role of estrogens in growth regulation of breast cancer. Crit Rev Oncog 1989;1:89-111.
12. Weisz A, Bresciani F. Estrogen regulation of proto-oncogenes coding for nuclear proteins. Crit Rev Oncog 1993;4:361-88.
13. Weisz A, Rosales R. Identification of an estrogen response element upstream of the human c-fos gene that binds the estrogen receptor and the AP-1 transcription factor. Nucleic Acids Res 1990;18:5097-106.
14. Hyder SM, Stancel GM, Nawaz Z, McDonnell DP, Loose-Mitchell DS. Identification of an estrogen response element in the 3′-flanking region of the murine c-fos protooncogene. J Biol Chem 1992;267:18047-54.
15. Dubik D, Shiu RP. Mechanism of estrogen activation of c-myc oncogene expression. Oncogene 1992;7:1587-94.
16. Cicatiello L, Ambrosino C, Coletta B, Scalona M, Sica V, Bresciani F, et al. Transcriptional activation of jun and actin genes by estrogen during mitogenic stimulation of rat uterine cells. J Steroid Biochem Mol Biol 1992;41:523-8.
17. Cicatiello L, Sica V, Bresciani F, Weisz A. Identification of a specific pattern of "immediate-early" gene activation induced by estrogen during mitogenic stimulation of rat uterine cells. Receptor 1993;3:17-30.
18. Hyder SM, Nawaz Z, Chiappetta C, Yokoyama K, Stancel GM. The protooncogene c-jun contains an unusual estrogen-inducible enhancer within the coding sequence. J Biol Chem 1995;270:8506-13.
19. Jensen AA. Environmental and occupational chemicals. In: Bennet PN, editor. Drugs and human lactation. New York: Elsevier Sci Publ, 1988;551-73.
20. Kutz FW, Wood PH, Bottimore DP. Organochlorine pesticides and polychlorinated biphenyls in human adipose tissue. Rev Environ Contam Toxicol 1991;120:1-82.
21. Wolff MS. Occupationally derived chemicals in breast milk. Am J Ind Med 1983;4:259-81.
22. Mussalo-Rauhamaa H. Partitioning and levels of neutral organochlorine compounds in human serum, blood cells, and adipose and liver tissue. Sci Total Environ 1991;103:159-75.
23. Rogan WJ, Gladen BC, McKinney JD, Carreras N, Hardy P, Thullen J, et al. Polychlorinated biphenyls (PCBs) and dichlorodiphenyl dichloroethene (DDE) in human milk: effects of maternal factors and previous lactation. Am J Public Health 1986;76:172-7.
24. Levine R. Recognized and possible effects of pesticides in humans. In: Hayes WJ Jr, Laws ER Jr, editors. Handbook of pesticide toxicology. Vol 1. General principles. San Diego:Academic Press, 1991:275-360.
25. Safe S. Toxicology, structure-function relationship, and human and environmental health impacts of polychlorinated biphenyls: progress and problems. Environ Health Perspect 1993;100:259-68.
26. International Agency for Research on Cancer. Overall evaluations of carcinogenicity: an update of IARC Monographs Volumes 1 to 42. Geneva: WHO, 1987:186-7.
27. Smith AG. Chlorinated hydrocarbon insecticides. In: Hayes WJ Jr, Laws ER Jr, editors. Handbook of pesticide toxicology. Vol 2. Classes of pesticides. San Diego: Academic Press, 1991:731-915.
28. Welch RM, Levin W, Conney AH. Estrogenic action of DDT and its analogs. Toxicol Appl Pharmacol 1969;14:358-67.
29. Kupfer D, Bulger WH. Estrogenic properties of DDT and its analogs. In: McLachlan J, editor. Estrogens in the environment. New York: Elsevier, 1980:239-63.
30. Bulger WH, Kupfer D. Estrogenic action of DDT analogs. Am J Ind Med 1983;4:163-73.
31. Scribner JD, Mottet NK. DDT acceleration of mammary gland tumors induced in the male Sprague-Dawley rat by 2-acetamidophenanthrene. Carcinogenesis 1981;2:1235-9.
32. Robison AK, Sirbasku DA, Stancel GM. DDT supports growth of an estrogen-responsive tumor. Toxicol Lett 1985;27:109-13.
33. Mason RR, Schulte GJ. Interaction of o,p′-DDT with the estrogen-binding protein (EBP) of DMBA-induced rat mammary tumors. Res Commun Chem Pathol Pharmacol 1981;33:119-28.
34. Kupfer D, Bulger WH. Interaction of o,p′-DDT with the estrogen-binding protein (EBP) in human mammary and uterine tumors. Res Commun Chem Pathol Pharmacol 1977;16:451-62.
35. Soto AM, Lin TM, Justicia H, Silvia RM, Sonnenscheim C. An "in culture" bioassay to access the estrogenicity of xenobiotics (E. screen). In: Colbom T, Clemens C, editors. Chemically induced alterations in sexual and functional development: the wild-life/human connection. Advances in modern environmental toxicology. Vol 21. Princeton (NJ): Princeton Scientific Publishing, 1992:107-12.
36. Miller FR, Soule HD, Tait L, Pauley RJ, Wolman SR, Dawson PJ, et al. Xenograft model of human proliferative breast disease. J Natl Cancer Inst 1993;85:1725-32.
37. Basolo F, Elliott J, Tait L, Chen XQ, Maloney T, Russo IH, et al. Transformation of human breast epithelial cells by c-Ha-ras oncogene. Mol Carcinog 1991;4:25-35.
38. Dawson PJ, Wolman SR, Tait L, Heppner GH, Miller FR. MCF10AT: a model for the evolution of cancer from proliferative breast disease. Am J Pathol 1996;148:313-9.
39. Shekhar PV, Chen ML, Werdell J, Heppner GH, Miller FR, Christman JK. Activation of the endogenous estrogen receptor gene in MCF10AT system cells, a potential factor for neoplastic progression of MCF10AT xenografts. Proc Am Assoc Cancer Res 1995;36:255.
40. Wiese TE, Kral LG, Dennis KE, Butler WB, Brooks SC. Optimization of estrogen growth response in MCF-7 cells. In Vitro Cell Dev Biol 1992; 28A:595-602.
41. Green B, Leake RE. Steroid hormones: a practical approach. Oxford (U.K.): IRL Press, 1987.
42. Bradford MM. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 1976;72:248-54.
43. VanderKuur JA, Hafner MS, Christman JK, Brooks SC. Effects of estradiol-17β analogues on activation of estrogen response element regulated chloramphenicol acetyltransferase expression. Biochemistry 1993:32: 7016-21.
44. Strahle U, Schmid W, Schutz G. Synergistic action of the glucocorticoid receptor with transcription factors. EMBO J 1988;7:3389-95.
45. Graham FL, Eb AJ van der. A new technique for the assay of infectivity of human adenovirus 5 DNA. Virology 1973;52:456-67.
46. Gorman CM, Moffat LF, Howard BH. Recombinant genomes which express chloramphenicol acetyltransferase in mammalian cells. Mol Cell Biol 1982;2:1044-51.
47. Brown AM, Jeltsch JM, Roberts M, Chambon P. Activation of pS2 gene transcription is a primary response to estrogen in the human breast cancer cell line MCF-7. Proc Natl Acad Sci U S A 1984;81:6344-8.
48. Pilat MJ, Christman JK, Brooks SC. Characterization of the estrogen receptor transfected MCF10A breast cell line 139B6. Breast Cancer Res Treat 1996;37:253-66.
49. Soule HD, Maloney TM, Wolman SR, Peterson WD Jr, Brenz R, McGrath CM, et al. Isolation and characterization of a spontaneously immortalized human breast epithelial cell line, MCF-10. Cancer Res 1990;50: 6075-86.
50. Masiakowski P, Breathnach R, Bloch J, Gannon F, Krust A, Chambon P. Cloning of cDNA sequences of hormone-regulated genes from the MCF-7 human breast cancer cell line. Nucleic Acids Res 1982;10:7895-903.
51. Nesaretnam K, Corcoran D, Dils RR, Darbre P. 3,4,3′,4′-Tetrachlorobiphenyl acts as an estrogen in vitro and in vivo. Mol Endocrinol 1996; 10:923-6.
52. Safe SH. Do environmental estrogens play a role in development of breast cancer in women and male reproductive problems? Hum Ecol Risk Assess 1995;1:17-23.
53. MacMahon B. Pesticide residues and breast cancer? [editorial]. J Natl Cancer Inst 1994;86:572-3.
54. Dewailly E, Dodin S, Verreault R, Ayotte P, Sauve L, Morin J, et al. High organochlorine body burden in women with estrogen receptor-positive breast cancer. J Natl Cancer Inst 1994;86:232-4.
55. Krieger N, Wolff MS, Hiatt RA, Rivera M, Vogeiman J, Orentreich N. Breast cancer and serum organochlorines: a prospective study among white, black, and Asian women. J Natl Cancer Inst 1994;86: 589-99.
56. Djordjevic MV, Hoffmann D, Fran J, Prokopczyk B, Citron ML, Stellman SD. Assessment of chlorinated pesticides and polychlorinated biphenyls in adipose breast tissue using a supercritical fluid extraction method. Carcinogenesis 1994;15:2581-5.
57. Zava DT, Blen M, Duwe G. Estrogenic activity of natural and synthetic estrogens in human breast cancer cells in culture. Environ Health Perspect 1997;105 Suppl 3:637-45.
58. Wolff MS, Toniolo PG, Lee EW, Rivera M, Dubin N. Blood levels of organochlorine residues and risk of breast cancer. J Natl Cancer Inst 1993; 85:648-52.
59. Kanja LW, Skaare JU, Ojwang SB, Maitai CK. A comparison of organochlorine pesticide residues in maternal adipose tissue, maternal blood, cord blood and human milk from mother/infant pairs. Arch Environ Contam Toxicol 1992;22:21-4.
60. Soto AM, Chung KL, Sonnenschein C. The pesticides endosulfan, toxaphene, and dieldrin have estrogenic effects on human estrogen-sensitive cells. Environ Health Perspect 1994;102:380-3.
61. Henderson BE, Ross RK, Pike MC. Toward the primary prevention of cancers. Science 1991;254:1131-8.
62. Lipworth L. Epidemiology of breast cancer. Eur J Cancer Prev 1995;4: 7-30.
63. Miller WR. Endocrine treatment for breast cancers: biological rationale and current progress. J Steroid Biochem Mol Biol 1990;37:467-80.
64. Steinmetz R, Young PC, Caperell-Grant A, Gize EA, Madhukar BV, Ben-Jonathan N, et al. Novel estrogenic action of the pesticide residue β-hexachlorocyclohexane in human breast cancer cells. Cancer Res 1996;56: 5403-9.