메뉴 건너뛰기




Volumn 59, Issue 19, 1999, Pages 4864-4869

Adrenal androgens stimulate the proliferation of breast cancer cells as direct activators of estrogen receptor α

Author keywords

[No Author keywords available]

Indexed keywords

5ALPHA ANDROSTENE 3BETA,17BETA DIOL; ANDROGEN; ANDROSTANOLONE; ANTIESTROGEN; AROMATASE INHIBITOR; ESTROGEN RECEPTOR; PRASTERONE; TESTOSTERONE; UNCLASSIFIED DRUG;

EID: 0033214658     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (140)

References (39)
  • 1
    • 0028079844 scopus 로고
    • The biology of breast cancer
    • Hoskins, K., and Weber, B. L. The biology of breast cancer. Curr. Opin. Oncol., 6: 554-559, 1994.
    • (1994) Curr. Opin. Oncol. , vol.6 , pp. 554-559
    • Hoskins, K.1    Weber, B.L.2
  • 2
    • 0028625491 scopus 로고
    • Insights from the study of animals lacking functional estrogen receptor
    • Washington DC
    • Korach, K. S. Insights from the study of animals lacking functional estrogen receptor. Science (Washington DC), 266: 1524-1527, 1994.
    • (1994) Science , vol.266 , pp. 1524-1527
    • Korach, K.S.1
  • 3
    • 0031755454 scopus 로고    scopus 로고
    • Recent advances in breast cancer biology
    • Eisen, A., and Weber, B. L. Recent advances in breast cancer biology. Curr. Opin. Oncol., 10: 486-491, 1998.
    • (1998) Curr. Opin. Oncol. , vol.10 , pp. 486-491
    • Eisen, A.1    Weber, B.L.2
  • 4
    • 0032187509 scopus 로고    scopus 로고
    • Designer estrogens
    • Jordan, V. Designer estrogens. Sci. Am., 279: 60-67, 1998.
    • (1998) Sci. Am. , vol.279 , pp. 60-67
    • Jordan, V.1
  • 5
    • 0032134252 scopus 로고    scopus 로고
    • Therapeutic potential of selective estrogen receptor modulators
    • Gustafsson, J-Å. Therapeutic potential of selective estrogen receptor modulators. Curr. Opin. Chem. Biol., 2: 508-511, 1998.
    • (1998) Curr. Opin. Chem. Biol. , vol.2 , pp. 508-511
    • Gustafsson, J.-A.1
  • 6
    • 0030959014 scopus 로고    scopus 로고
    • Steroid-independent activation of steroid receptors in mammalian and yeast cells and in breast cancer
    • Picard, D., Bunone, G., Liu, S. W., and Donzé, O. Steroid-independent activation of steroid receptors in mammalian and yeast cells and in breast cancer. Biochem. Soc. Trans., 25: 597-602, 1997.
    • (1997) Biochem. Soc. Trans. , vol.25 , pp. 597-602
    • Picard, D.1    Bunone, G.2    Liu, S.W.3    Donzé, O.4
  • 7
    • 0030004535 scopus 로고    scopus 로고
    • Growth inhibition by anti-estrogens and progestins in TGF-β-resistant and -sensitive breast-tumor cells
    • Kalkhoven, E., Beraldi, E., Panno, M. L., De Winter, J. P., Thijssen, J. H., and Van Der Burg, B. Growth inhibition by anti-estrogens and progestins in TGF-β-resistant and -sensitive breast-tumor cells. Int. J. Cancer, 65: 682-687, 1996.
    • (1996) Int. J. Cancer , vol.65 , pp. 682-687
    • Kalkhoven, E.1    Beraldi, E.2    Panno, M.L.3    De Winter, J.P.4    Thijssen, J.H.5    Van Der Burg, B.6
  • 8
    • 0033037866 scopus 로고    scopus 로고
    • Ligand-independent activation of steroid receptors: New roles for old players
    • Cenni, B., and Picard, D. Ligand-independent activation of steroid receptors: new roles for old players. Trends Endocrinol. Metab., 10: 41-46, 1999.
    • (1999) Trends Endocrinol. Metab. , vol.10 , pp. 41-46
    • Cenni, B.1    Picard, D.2
  • 9
    • 0028853923 scopus 로고
    • Estrogen deprivation causes estradiol hypersensitivity in human breast cancer cells
    • Masamura, S., Santner, S. J., Heitjan, D. F., and Santen, R. J. Estrogen deprivation causes estradiol hypersensitivity in human breast cancer cells. J. Clin. Endocrinol. Metab., 80: 2918-2925, 1995.
    • (1995) J. Clin. Endocrinol. Metab. , vol.80 , pp. 2918-2925
    • Masamura, S.1    Santner, S.J.2    Heitjan, D.F.3    Santen, R.J.4
  • 11
    • 0031027033 scopus 로고    scopus 로고
    • Aromatase activity and expression in breast cancer and benign breast tissue stromal cells
    • Santner, S. J., Pauley, R. J., Tait, L., Kaseta, J., and Santen, R. J. Aromatase activity and expression in breast cancer and benign breast tissue stromal cells. J. Clin. Endocrinol. Metab., 82: 200-208, 1997.
    • (1997) J. Clin. Endocrinol. Metab. , vol.82 , pp. 200-208
    • Santner, S.J.1    Pauley, R.J.2    Tait, L.3    Kaseta, J.4    Santen, R.J.5
  • 12
    • 0031974628 scopus 로고    scopus 로고
    • Determinants of ligand specificity of estrogen receptor-α: Estrogen versus androgen discrimination
    • Ekena, K., Katzenellenbogen, J. A., and Katzenellenbogen, B. S. Determinants of ligand specificity of estrogen receptor-α: estrogen versus androgen discrimination. J. Biol. Chem., 273: 693-699, 1998.
    • (1998) J. Biol. Chem. , vol.273 , pp. 693-699
    • Ekena, K.1    Katzenellenbogen, J.A.2    Katzenellenbogen, B.S.3
  • 13
    • 0031039888 scopus 로고    scopus 로고
    • Comparison of the ligand binding specificity and transcript tissue distribution of estrogen receptors α and β
    • Kuiper, G. G., Carlsson, B., Grandien, K., Enmark, E., Haggblad, J., Nilsson, S., and Gustafsson, J. A. Comparison of the ligand binding specificity and transcript tissue distribution of estrogen receptors α and β. Endocrinology, 138; 863-870, 1997.
    • (1997) Endocrinology , vol.138 , pp. 863-870
    • Kuiper, G.G.1    Carlsson, B.2    Grandien, K.3    Enmark, E.4    Haggblad, J.5    Nilsson, S.6    Gustafsson, J.A.7
  • 14
    • 0019820902 scopus 로고
    • Estrogenic effects of physiological concentrations of 5-androstene-3β,17β-diol and its metabolism in MCF7 human breast cancer cells
    • Adams, J., Garcia, M., and Rochefort, H. Estrogenic effects of physiological concentrations of 5-androstene-3β,17β-diol and its metabolism in MCF7 human breast cancer cells. Cancer Res., 41: 4720-4726, 1981.
    • (1981) Cancer Res. , vol.41 , pp. 4720-4726
    • Adams, J.1    Garcia, M.2    Rochefort, H.3
  • 15
    • 0022536513 scopus 로고
    • Stimulation of cell proliferation and estrogenic response by adrenal C19-Δ5-steroids in the ZR-75-1 human breast cancer cell line
    • Poulin, R., and Labrie, F. Stimulation of cell proliferation and estrogenic response by adrenal C19-Δ5-steroids in the ZR-75-1 human breast cancer cell line. Cancer Res., 46: 4933-4937, 1986.
    • (1986) Cancer Res. , vol.46 , pp. 4933-4937
    • Poulin, R.1    Labrie, F.2
  • 16
    • 0032217322 scopus 로고    scopus 로고
    • C19 steroids estrogenic activity in human breast cancer cell lines: Importance of dehydroepiandrosterone sulfate at physiological plasma concentration
    • Le Bail, J. C., Marre-Fournier, F., Nicolas, J. C., and Habrioux, G. C19 steroids estrogenic activity in human breast cancer cell lines: importance of dehydroepiandrosterone sulfate at physiological plasma concentration. Steroids, 63: 678-683, 1998.
    • (1998) Steroids , vol.63 , pp. 678-683
    • Le Bail, J.C.1    Marre-Fournier, F.2    Nicolas, J.C.3    Habrioux, G.4
  • 17
    • 0031947016 scopus 로고    scopus 로고
    • Dehydroepiandrosterone sulfate estrogenic action at its physiological plasma concentration in human breast cancer cell lines
    • Le Bail, J. C., Allen, K., Nicolas, J. C., and Habrioux, G. Dehydroepiandrosterone sulfate estrogenic action at its physiological plasma concentration in human breast cancer cell lines. Anticancer Res., 18: 1683-1688, 1998.
    • (1998) Anticancer Res. , vol.18 , pp. 1683-1688
    • Le Bail, J.C.1    Allen, K.2    Nicolas, J.C.3    Habrioux, G.4
  • 18
    • 0025359783 scopus 로고
    • Biological effects of adrenal androgens on MCF-7 and BT-20 human breast cancer cells
    • Najid, A., and Habrioux, G. Biological effects of adrenal androgens on MCF-7 and BT-20 human breast cancer cells. Oncology, 47: 269-274, 1990.
    • (1990) Oncology , vol.47 , pp. 269-274
    • Najid, A.1    Habrioux, G.2
  • 20
    • 0026699122 scopus 로고
    • Influence of dehydroepiandrosterone and 5-en-androstene-3β,17β-diol on the growth of MCF-7 human breast cancer cells induced by 17β-estradiol
    • Boccuzzi, G., Brignardello, E., di Monaco, M., Forte, C., Leonardi, L., and Pizzini, A. Influence of dehydroepiandrosterone and 5-en-androstene-3β,17β-diol on the growth of MCF-7 human breast cancer cells induced by 17β-estradiol. Anticancer Res., 12: 799-803, 1992.
    • (1992) Anticancer Res. , vol.12 , pp. 799-803
    • Boccuzzi, G.1    Brignardello, E.2    Di Monaco, M.3    Forte, C.4    Leonardi, L.5    Pizzini, A.6
  • 21
    • 0029877913 scopus 로고    scopus 로고
    • Activation of the unliganded estrogen receptor by EGF involves the MAP kinase pathway and direct phosphorylation
    • Bunone, G., Briand, P-A., Miksicek, R. J., and Picard, D. Activation of the unliganded estrogen receptor by EGF involves the MAP kinase pathway and direct phosphorylation. EMBO J., 15: 2174-2183, 1996.
    • (1996) EMBO J. , vol.15 , pp. 2174-2183
    • Bunone, G.1    Briand, P.-A.2    Miksicek, R.J.3    Picard, D.4
  • 23
    • 0006694522 scopus 로고    scopus 로고
    • Regulation of heterologous proteins by fusion to a hormone binding domain
    • D. Picard (ed.), Oxford, United Kingdom: Oxford University Press
    • Picard, D. Regulation of heterologous proteins by fusion to a hormone binding domain. In: D. Picard (ed.), Nuclear Receptors: A Practical Approach. Oxford, United Kingdom: Oxford University Press, 1999.
    • (1999) Nuclear Receptors: A Practical Approach
    • Picard, D.1
  • 24
    • 0027052876 scopus 로고
    • Different activation domains stimulate transcription from remote (enhancer) and proximal (promoter) positions
    • Seipel, K., Georgiev, O., and Schaffner, W. Different activation domains stimulate transcription from remote (enhancer) and proximal (promoter) positions. EMBO J., 11: 4961-4968, 1992.
    • (1992) EMBO J. , vol.11 , pp. 4961-4968
    • Seipel, K.1    Georgiev, O.2    Schaffner, W.3
  • 25
    • 0032520155 scopus 로고    scopus 로고
    • Bioactive steroids as contaminants of the common carbon source galactose
    • Liu, J. W., and Picard, D. Bioactive steroids as contaminants of the common carbon source galactose. FEMS Microbiol. Lett., 159: 167-171, 1998.
    • (1998) FEMS Microbiol. Lett. , vol.159 , pp. 167-171
    • Liu, J.W.1    Picard, D.2
  • 26
    • 0026030413 scopus 로고
    • Vectors for constitutive and inducible gene expression in yeast
    • Schena, M., Picard, D., and Yamamoto, K. R. Vectors for constitutive and inducible gene expression in yeast. Methods Enzymol., 194: 389-398, 1991.
    • (1991) Methods Enzymol. , vol.194 , pp. 389-398
    • Schena, M.1    Picard, D.2    Yamamoto, K.R.3
  • 28
    • 0021710272 scopus 로고
    • Use of lacZ fusions to delimit regulatory elements of the inducible divergent GAL1-GAL10 promoter in Saccharomyces cerevisiae
    • Yocum, R. R., Hanley, S., West, R. W., Jr., and Ptashne, M. Use of lacZ fusions to delimit regulatory elements of the inducible divergent GAL1-GAL10 promoter in Saccharomyces cerevisiae. Mol. Cell. Biol., 4: 1985-1998, 1984.
    • (1984) Mol. Cell. Biol. , vol.4 , pp. 1985-1998
    • Yocum, R.R.1    Hanley, S.2    West R.W., Jr.3    Ptashne, M.4
  • 29
    • 0028021514 scopus 로고
    • Mutational analysis of cysteine residues within the hormone-binding domain of the human estrogen receptor identifies mutants that are defective in both DNA-binding and subcellular distribution
    • Neff, S., Sadowski, C., and Miksicek, R. J. Mutational analysis of cysteine residues within the hormone-binding domain of the human estrogen receptor identifies mutants that are defective in both DNA-binding and subcellular distribution. Mol. Endocrinol., 8: 1215-1223, 1994.
    • (1994) Mol. Endocrinol. , vol.8 , pp. 1215-1223
    • Neff, S.1    Sadowski, C.2    Miksicek, R.J.3
  • 30
    • 0021327660 scopus 로고
    • Estrogen receptor synthesis and turnover in MCF-7 breast cancer cells measured by a density shift technique
    • Eckert, R. L., Mullick, A., Rorke, E. A., and Katzenellenbogen, B. S. Estrogen receptor synthesis and turnover in MCF-7 breast cancer cells measured by a density shift technique. Endocrinology, 114: 629-637, 1984.
    • (1984) Endocrinology , vol.114 , pp. 629-637
    • Eckert, R.L.1    Mullick, A.2    Rorke, E.A.3    Katzenellenbogen, B.S.4
  • 31
    • 0030990377 scopus 로고    scopus 로고
    • Oligonucleotide squelching reveals the mechanism of estrogen receptor autologous down-regulation
    • Santagati, S., Gianazza, E., Agrati, P., Vegeto, E., Patrone, C., Pollio, G., and Maggi, A. Oligonucleotide squelching reveals the mechanism of estrogen receptor autologous down-regulation. Mol. Endocrinol., 11: 938-949, 1997.
    • (1997) Mol. Endocrinol. , vol.11 , pp. 938-949
    • Santagati, S.1    Gianazza, E.2    Agrati, P.3    Vegeto, E.4    Patrone, C.5    Pollio, G.6    Maggi, A.7
  • 32
    • 0023895442 scopus 로고
    • The human estrogen receptor functions in yeast
    • Lond.
    • Metzger, D., White, J. H., and Chambon, P. The human estrogen receptor functions in yeast. Nature (Lond.), 334: 31-36, 1988.
    • (1988) Nature , vol.334 , pp. 31-36
    • Metzger, D.1    White, J.H.2    Chambon, P.3
  • 33
    • 0027073107 scopus 로고
    • Genetic dissection of the signaling domain of a mammalian steroid receptor in yeast
    • Garabedian, M. J., and Yamamoto, K. R. Genetic dissection of the signaling domain of a mammalian steroid receptor in yeast. Mol. Biol. Cell, 3: 1245-1257, 1992.
    • (1992) Mol. Biol. Cell , vol.3 , pp. 1245-1257
    • Garabedian, M.J.1    Yamamoto, K.R.2
  • 34
    • 0029013333 scopus 로고
    • LEM1, an ATP-binding-cassette transporter, selectively modulates the biological potency of steroid hormones
    • Kralli, A., Bohen, S. P., and Yamamoto, K. R. LEM1, an ATP-binding-cassette transporter, selectively modulates the biological potency of steroid hormones. Proc. Natl. Acad. Sci. USA, 92: 4701-4705, 1995.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 4701-4705
    • Kralli, A.1    Bohen, S.P.2    Yamamoto, K.R.3
  • 35
    • 0031465938 scopus 로고    scopus 로고
    • Dehydroepiandrosterone stimulates the estrogen response element
    • Bruder, J. M., Sobek, L., and Oettel, M. Dehydroepiandrosterone stimulates the estrogen response element. J. Steroid Biochem. Mol. Biol., 62: 461-466, 1997.
    • (1997) J. Steroid Biochem. Mol. Biol. , vol.62 , pp. 461-466
    • Bruder, J.M.1    Sobek, L.2    Oettel, M.3
  • 37
    • 0031712804 scopus 로고    scopus 로고
    • Intratumoral aromatase in human breast, endometrial, and ovarian malignancies
    • Sasarro, H., and Harada, N. Intratumoral aromatase in human breast, endometrial, and ovarian malignancies. Endocr. Rev., 19: 593-607, 1998.
    • (1998) Endocr. Rev. , vol.19 , pp. 593-607
    • Sasarro, H.1    Harada, N.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.