Sulfotransferase 2B1b in human breast: Differences in subcellular localization in African American and Caucasian women

Journal of Steroid Biochemistry and Molecular Biology

Volumn 111, Issue 3-5, 2008, Pages 171-177

  Dumas, Nicole A ^a   He, Dongning ^a   Frost, Andra R ^b   Falany, Charles N ^a  

^a University of Alabama at Birmingham   (United States)

^b University of Alabama at Birmingham   (United States)

Author keywords

Estradiol; African American; Breast cancer; Caucasian; Dehydroepiandrosterone; Sulfation; Sulfotransferase; SULT2B1b

Indexed keywords

ESTROGEN; PRASTERONE; SULFOTRANSFERASE; SULFOTRANSFERASE 2B1B;

ADULT; AFRICAN AMERICAN; ARTICLE; BREAST CANCER; BREAST EPITHELIUM; CAUCASIAN; CELL FRACTIONATION; CELL NUCLEUS; CONTROLLED STUDY; CYTOSOL; DISEASE COURSE; ENZYME ACTIVITY; EPITHELIUM CELL; FEMALE; HORMONAL REGULATION; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; POSTMENOPAUSE; PROTEIN EXPRESSION; RACE DIFFERENCE; SULFATION; WOMEN'S HEALTH;

AFRICAN AMERICANS; ANIMALS; BREAST; BREAST NEOPLASMS; CELL LINE, TUMOR; DEHYDROEPIANDROSTERONE; EUROPEAN CONTINENTAL ANCESTRY GROUP; FEMALE; HUMANS; SULFOTRANSFERASES;

EID: 49449115829     PISSN: 09600760     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jsbmb.2008.05.006     Document Type: Article

References (38)

1. ACS, Breast cancer facts and figures 2005-2006, American Cancer Society, Inc., Atlanta, 2006.
2. Adly L., Hill D., Sherman M.E., Sturgeon S.R., Fears T., Mies C., Ziegler R.G., Hoover R.N., and Schairer C. Serum concentrations of estrogens, sex hormone-binding globulin, and androgens and risk of breast cancer in postmenopausal women. Int. J. Cancer 119 (2006) 2402-2407
3. Labrie F. Dehydroepiandrosterone, androgens and the mammary gland. Gynecol. Endocrinol. 22 (2006) 118-130
4. Mo Q., Lu S.F., and Simon N.G. Dehydroepiandrosterone and its metabolites: differential effects on androgen receptor trafficking and transcriptional activity. J. Steroid Biochem. Mol. Biol. 99 (2006) 50-58
5. Chen F., Knecht K., Birzin E., Fisher J., Wilkinson H., Mojena M., Moreno C.T., Schmidt A., Harada S., Freedman L.P., and Reszka A.A. Direct agonist/antagonist functions of dehydroepiandrosterone. Endocrinology 146 (2005) 4568-4576
6. Falany C.N., Wheeler J., Oh T.S., and Falany J.L. Steroid sulfation by expressed human cytosolic sulfotransferases. J. Steroid Biochem. Mol. Biol. 48 (1994) 369-375
7. Falany C.N. Enzymology of human cytosolic sulfotransferases. Faseb J. 11 (1997) 206-216
8. Falany C.N., He D., Dumas N., Frost A.R., and Falany J.L. Human cytosolic sulfotransferase 2B1: isoform expression, tissue specificity and subcellular localization. J. Steroid Biochem. Mol. Biol. 102 (2006) 214-221
9. Her C., Wood T.C., Eichler E.E., Mohrenweiser H.W., Ramagli L.S., Siciliano M.J., and Weinshilboum R.M. Human hydroxysteroid sulfotransferase SULT2B1: two enzymes encoded by a single chromosome 19 gene. Genomics 53 (1998) 284-295
10. He D., Meloche C.A., Dumas N.A., Frost A.R., and Falany C.N. Different subcellular localization of sulfotransferase 2B1b (SULT2B1b) in human placenta and prostate. Biochem. J. 379 (2004) 533-540
11. He D., Frost A.R., and Falany C.N. Identification and immunohistochemical localization of Sulfotransferase 2B1b (SULT2B1b) in human lung. Biochim. Biophys. Acta 1724 (2005) 119-126
12. Higashi Y., Fuda H., Yanai H., Lee Y., Fukushige T., Kanzaki T., and Strott C.A. Expression of cholesterol sulfotransferase (SULT2B1b) in human skin and primary cultures of human epidermal keratinocytes. J. Invest. Dermatol. 122 (2004) 1207-1213
13. Geese W.J., and Raftogianis R.B. Biochemical characterization and tissue distribution of human SULT2B1. Biochem. Biophys. Res. Commun. 288 (2001) 280-289
14. Meloche C.A., and Falany C.N. Expression and characterization of the human 3 beta-hydroxysteroid sulfotransferases (SULT2B1a and SULT2B1b). J. Steroid Biochem. Mol. Biol. 77 (2001) 261-269
15. He D., and Falany C.N. Characterization of proline-serine-rich carboxyl terminus in human sulfotransferase 2B1b: immunogenicity, subcellular localization, kinetic properties, and phosphorylation. Drug Metab. Dispos. 34 (2006) 1749-1755
16. Graham J., Ford T., and Rickwood D. The preparation of subcellular organelles from mouse liver in self-generated gradients of iodixanol. Anal. Biochem. 220 (1994) 367-373
17. Provost J., Fudge J., Israelit S., Siddiqi A.R., and Exton J.H. Tissue-specific distribution and subcellular distribution of phospholipase D in rat: evidence for distinct RhoA- and ADP-ribosylation factor (ARF)-regulated isoenzymes. Biochem. J. 319 (1996) 285-291
18. Falany C.N., Vazquez M.E., and Kalb J.M. Purification and characterization of human liver dehydroepiandrosterone sulphotransferase. Biochem. J. 260 (1989) 641-646
19. Frost A.R., Sparks D., and Grizzle W.E. Methods of antigen recovery vary in their usefulness in unmasking specific antigens in immunohistochemistry. Appl. Immunohistochem. Mol. Morphol. 8 (2000) 236-243
20. Talley L.I., Grizzle W.E., Waterbor J.W., Brown D., Weiss H., and Frost A.R. Hormone receptors and proliferation in breast carcinomas of equivalent histologic grades in pre- and postmenopausal women. Int. J. Cancer 98 (2002) 118-127
21. Falany J.L., and Falany C.N. Expression of cytosolic sulfotransferases in normal mammary epithelial cells and breast cancer cell lines. Cancer Res. 56 (1996) 1551-1555
22. Ji Y., Moon I., Zlatkovic J., Salavaggione O.E., Thomae B.A., Eckloff B.W., Wieben E.D., Schaid D.J., and Weinshilboum R.M. Human hydroxysteroid sulfotransferase SULT2B1 pharmacogenomics: gene sequence variation and functional genomics. J. Pharmacol. Exp. Ther. 322 (2007) 529-540
23. Fuda H., Javitt N.B., Mitamura K., Ikegawa S., and Strott C.A. Oxysterols are substrates for cholesterol sulfotransferase. J. Lipid Res. 48 (2007) 1343-1352
24. Meloche, CA, The activity and expression of the sulfotransferase 2b1 isoforms in human prostate, placenta, breast and skin, in: Pharmacology, University of Alabama at Birmingham, Birmingham, 2003.
25. He D., and Falany C.N. Inhibition of SULT2B1b expression alters effects of 3beta-hydroxysteroids on cell proliferation and steroid hormone receptor expression in human LNCaP prostate cancer cells. Prostate 67 (2007) 1318-1329
26. Labrie F., Luu-The V., Labrie C., and Simard J. DHEA and its transformation into androgens and estrogens in peripheral target tissues: intracrinology. Front Neuroendocrinol. 22 (2001) 185-212
27. Missmer S.A., Eliassen A.H., Barbieri R.L., and Hankinson S.E. Endogenous estrogen, androgen, and progesterone concentrations and breast cancer risk among postmenopausal women. J. Natl. Cancer Inst. 96 (2004) 1856-1865
28. Helzlsouer K.J., Gordon G.B., Alberg A.J., Bush T.L., and Comstock G.W. Relationship of prediagnostic serum levels of dehydroepiandrosterone and dehydroepiandrosterone sulfate to the risk of developing premenopausal breast cancer. Cancer Res. 52 (1992) 1-4
29. Pasqualini J.R. Role of androgens in breast cancer. J. Steroid Biochem. Mol. Biol. 45 (1993) 167-172
30. Zumoff B., Levin J., Rosenfeld R.S., Markham M., Strain G.W., and Fukushima D.K. Abnormal 24-hr mean plasma concentrations of dehydroisoandrosterone and dehydroisoandrosterone sulfate in women with primary operable breast cancer. Cancer Res. 41 (1981) 3360-3363
31. Gordon G.B., Bush T.L., Helzlsouer K.J., Miller S.R., and Comstock G.W. Relationship of serum levels of dehydroepiandrosterone and dehydroepiandrosterone sulfate to the risk of developing postmenopausal breast cancer. Cancer Res. 50 (1990) 3859-3862
32. Johnson M.D., Bebb R.A., and Sirrs S.M. Uses of DHEA in aging and other disease states. Ageing Res. Rev. 1 (2002) 29-41
33. Mehrotra J., Ganpat M.M., Kanaan Y., Fackler M.J., McVeigh M., Lahti-Domenici J., Polyak K., Argani P., Naab T., Garrett E., Parmigiani G., Broome C., and Sukumar S. Estrogen receptor/progesterone receptor-negative breast cancers of young African-American women have a higher frequency of methylation of multiple genes than those of Caucasian women. Clin. Cancer Res. 10 (2004) 2052-2057
34. Ademuyiwa F.O., and Olopade O.I. Racial differences in genetic factors associated with breast cancer. Cancer Metastasis Rev. 22 (2003) 47-53
35. De Jesus M.A., Fujita M., Kim K.S., and Goldson A.L. Retrospective analysis of breast cancer among young African American females. Breast Cancer Res. Treat. 78 (2003) 81-87
36. Trock B.J. Breast cancer in African American women: epidemiology and tumor biology. Breast Cancer Res. Treat. 40 (1996) 11-24
37. Gray G.E., Henderson B.E., and Pike M.C. Changing ratio of breast cancer incidence rates with age of black females compared with white females in the United States. J. Natl. Cancer Inst. 64 (1980) 461-463
38. Marbella A.M., and Layde P.M. Racial trends in age-specific breast cancer mortality rates in US women. Am. J. Public Health 91 (2001) 118-121