The sweet taste quality is linked to a cluster of taste fibers in primates: Lactisole diminishes preference and responses to sweet in S fibers (sweet best) chorda tympani fibers of M. fascicularis monkey

BMC Physiology

Volumn 9, Issue 1, 2009, Pages

  Wang, Yiwen ^a   Danilova, Vicktoria ^a   Cragin, Tiffany ^a   Roberts, Thomas W ^a   Koposov, Alexey ^a   Hellekant, Göran ^a  

^a UNIVERSITY OF MINNESOTA MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL RESPONSE MODIFIER; LACTISOLE; SUGAR; SWEETENING AGENT; UNCLASSIFIED DRUG; BENZENE DERIVATIVE; CITRIC ACID; G PROTEIN COUPLED RECEPTOR; GLUTAMATE SODIUM; GLYCOPROTEIN; MIRACULIN PROTEIN, SYNSEPALUM DULCIFICUM; SODIUM CHLORIDE;

ARTICLE; CHORDA TYMPANI; CONTROLLED STUDY; FEMALE; FLUID INTAKE; MONKEY; NONHUMAN; PRIMATE; SWEETNESS; TASTE; TASTE BUD; TASTE PREFERENCE; TONGUE; ANIMAL; CLASSIFICATION; COMPARATIVE STUDY; DRINKING BEHAVIOR; DRUG EFFECT; HUMAN; MACACA; NERVE FIBER; PHYSIOLOGY; SPECIES DIFFERENCE;

ANIMALS; BENZENE DERIVATIVES; CHORDA TYMPANI NERVE; CITRIC ACID; DRINKING BEHAVIOR; FEMALE; GLYCOPROTEINS; HUMANS; MACACA FASCICULARIS; NERVE FIBERS; RECEPTORS, G-PROTEIN-COUPLED; SODIUM CHLORIDE; SODIUM GLUTAMATE; SPECIES SPECIFICITY; SWEETENING AGENTS; TASTE; TASTE BUDS;

EID: 63849254154     PISSN: None     EISSN: 14726793     Source Type: Journal    
DOI: 10.1186/1472-6793-9-1     Document Type: Article

References (81)

1. T2Rs function as bitter taste receptors. J Chandrashekar KL Mueller MA Hoon E Adler L Feng W Guo CS Zuker NJ Ryba, Cell 2000 100 6 703 711 10.1016/S0092-8674(00)80706-0 10761935
2. Mammalian sweet taste receptors. G Nelson MA Hoon J Chandrashekar Y Zhang NJ Ryba CS Zuker, Cell 2001 106 3 381 390 10.1016/S0092-8674(01)00451-2 11509186
3. Coding of sweet, bitter, and umami tastes: different receptor cells sharing similar signaling pathways. Y Zhang MA Hoon J Chandrashekar KL Mueller B Cook D Wu CS Zuker NJ Ryba, Cell 2003 112 3 293 301 10.1016/S0092-8674(03) 00071-0 12581520
4. The receptors for mammalian sweet and umami taste. GQ Zhao Y Zhang MA Hoon J Chandrashekar I Erlenbach NJ Ryba CS Zuker, Cell 2003 115 3 255 266 10.1016/S0092-8674(03)00844-4 14636554
5. The receptors and coding logic for bitter taste. KL Mueller MA Hoon I Erlenbach J Chandrashekar CS Zuker NJ Ryba, Nature 2005 434 7030 225 229 10.1038/nature03352 15759003
6. The receptors and cells for mammalian taste. J Chandrashekar M Hoon N Ryba C Zuker, Nature 2006 444 288 294 10.1038/nature05401 17108952
7. The cells and logic for mammalian sour taste detection. AL Huang X Chen MA Hoon J Chandrashekar W Guo D Trankner NJ Ryba CS Zuker, Nature 2006 442 7105 934 938 16929298 10.1038/nature05084
8. Action potentials in the glossopharyngeal nerve and in the chorda tympani. Y Zotterman, Skandinavisches Archiv für Physiologie 1935 72 73 77
9. Pseudogenization of a sweet-receptor gene accounts for cats' indifference toward sugar. X Li W Li H Wang J Cao K Maehashi L Huang AA Bachmanov DR Reed V Legrand-Defretin GK Beauchamp, PLoS genetics 2005 1 1 27 35 16103917 10.1371/journal.pgen.0010003
10. The sweet taste fibres of the dog. B Andersson S Landgren L Olsson Y Zotterman, Acta Physiology Scand 1950 21 105 119 10.1111/j.1748-1716.1950. tb00718.x
11. Studies on the nervous mechanism of taste. Y Zotterman, Exp Cell Res 1959 14 Suppl 5 520 526 13586308
12. The response pattern of taste fibres in the chorda tympani of the monkey. G Gordon R Kitchell L Strom Y Zotterman, Acta Physiologica Scandivanica 1959 46 119 132 10.1111/j.1748-1716.1959.tb01741.x
13. Sensory neural patterns and gustation. RP Erickson, Olfaction and Taste Oxford, London, New York, Paris: Pergamon Press, Zotterman Y, 1963 1 205 213
14. The evolution of neural coding ideas in the chemical senses. RP Erickson, Physiology & behavior 2000 69 1-2 3 13 10.1016/S0031-9384(00)00193-1 10854913
15. Issues of gustatory neural coding: where they stand today. TR Scott BK Giza, Physiology & behavior 2000 69 1-2 65 76 10.1016/S0031-9384(00)00189-X 10854918
16. The neural processing of taste. CH Lemon DB Katz, BMC neuroscience 2007 8 Suppl 3 S5 17903281 10.1186/1471-2202-8-S3-S5
17. Selective inhibition of sweetness by the sodium salt of +/-2-(4-methoxyphenoxy)propanoic acid. SS Schiffman BJ Booth EA Sattely-Miller BG Graham KM Gibes, Chem Senses 1999 24 4 439 447 10.1093/chemse/24.4.439 10480680
18. Less common high-potency sweeteners. AD Kinghorn CM Compadre, Alternative Sweeteners Edited by Nabors LOB, 3rd edn: CRC Press 2001 209 234
19. The liaison of sweet and savory. V Galindo-Cuspinera PA Breslin, Chem Senses 2006 31 3 221 225 10.1093/chemse/bjj022 16384922
20. Whole nerve and single fiber recordings in non-human primates. G Hellekant TW Roberts, Experimental Cell Biology of Taste and Olfaction: Current Techniques and Protocols Boca Raton, New York, London, Tokyo: CRC Press, Spielman AI, Brand JG, 1995 277 290
21. A method to measure taste qualities, taste intensity and temporal profile of compounds aimed at human consumption by taste nerve recordings in monkeys. G Hellekant A Wang, Sweetness and Sweeteners: Biology, Chemistry and Psychophysics Edited by Weerasinghe DK, Dubois GE, vol. ACS Symposium Series 979: Oxford University Press 2008 185 201
22. A metric for the breadth of turning of gustatory neurons. DV Smith JB Travers, Chem Sens Flavor 1979 4 3 215 229 10.1093/chemse/4.3.215
23. Electrophysiological recordings of mammalian taste nerves. V Danilova Y Danilov T Roberts D Elmer G Hellekant, Methods and Frontiers in Neuroscience Boka Raton, London, New York, Washington D.C.: CRC Press, Simon SA, Nicolelis MAL, 2002 239 264
24. Order Primates. RM Nowak, Walker's Mammals of the world Baltimore and London: John Hopkins 5 1991 II 472
25. Gustatory responsiveness of chorda tympany fibers in cynomolgus monkey. M Sato H Ogawa S Yamashita, Chem Senses 1994 19 5 381 400 10.1093/chemse/19.5.381 7881972
26. The effect of miraculin on the taste buds of man, monkey and rat. H Diamant G Hellekant Y Zotterman, Olfaction and Taste IV Stuttgart: Wissenschaftlige Verlagsgesellschaft MB4 Stuttgart, Schneider D, 1972 241 244
27. On the gustatory effects of miraculin and gymnemic acid in monkey. G Hellekant EC Hagstrom Y Kasahara Y Zotterman, Chem Sens Flavor 1974 1 137 145 10.1093/chemse/1.2.137
28. Gustatory effects of miraculin, monellin and thaumatin in the Saguinus midas tamarin monkey studied with electrophysiological and behavioural techniques. G Hellekant D Glaser JN Brouwer H van der Wel, Acta Physiologica Scandinavica 1976 97 2 241 250 10.1111/j.1748-1716.1976.tb10257.x 821313
29. Effects of Miraculin and Gymnemic acid in the Rhesus monkey (Macaca mulatta). G Hellekant, Food Intake and Chemical Senses Tokyo: University of Tokyo Press, Katsuki Y, Sato M, Takagi SF, Oomura Y, 1977 201 210
30. The sweetness-inducing effect of miraculin; behavioural and neurophysiological experiments in the rhesus monkey Macaca mulatta. JN Brouwer D Glaser Af Hard C Segerstad G Hellekant Y Ninomiya H Van der Wel, Journal of Physiology 1983 337 221 240 6875928
31. Effects of Gymnema sylvestre and Synesepalum dulcificum on taste in man. LM Bartoshuk GP Dateo DJ Vandenbelt RL Buttrick L Long Jr, Olfaction and Taste 1969 1 436 449
32. Gymnema sylvestre. P Edgeworth, PharmJ 1847 48 351
33. Isolation and mechanism of taste modifiers; taste-modifying protein and gymnemic acids. K Kurihara Y Kurihara LM Beidler, Olfaction & Taste III New York: The Rockefeller University Press, Pfaffmann C, 1 1969 1 450 469
34. Antisweet activity of gymnemic acid A1 and its derivatives. Y Kurihara, Life sciences 1969 8 9 537 543 10.1016/0024-3205(69)90449-4 5791706
35. A comparison of neural and psychophysical responses to taste stimuli in man. H Diamant B Oakley L Strom C Wells Y Zotterman, Acta Physiol Scand 1965 64 67 74 10.1111/j.1748-1716.1965.tb04154.x 14348506
36. Taste responses of human Chorda tympani nerve. B Oakley, Chem Senses 1985 10 4 469 481 10.1093/chemse/10.4.469
37. Taste in chimpanzee: I. The summated response to sweeteners and the effect of gymnemic acid. G Hellekant Y Ninomiya GE DuBois V Danilova TW Roberts, Physiology & behavior 1996 60 2 469 479 10.1016/S0031-9384(96)80021-7 8840908
38. Taste in chimpanzees II: single chorda tympani fibers. G Hellekant Y Ninomiya V Danilova, Physiol Behav 1997 61 6 829 841 10.1016/S0031-9384(96) 00562-8 9177554
39. Taste in chimpanzees III: Labeled line coding in sweet taste. G Hellekant Y Ninomiya V Danilova, Physiol Behav 1998 65 2 191 200 10.1016/S0031-9384(97) 00532-5 9855466
40. Monkey electrophysiological responses to brazzein mutants-where are the critical regions for brazzein's sweet taste. Z Jin V Danilova F Assadi-Porter Q Zhao D Aceti J Markley G Hellekant, 2nd International Symposium on Sweetener: 2002; Hiroshima, Japan 2002 143 P-128
41. Monkey electrophysiological and human psychophysical responses to mutants of the sweet protein brazzein: delineating brazzein sweetness. Z Jin V Danilova FM Assadi-Porter JL Markley G Hellekant, Chem Senses 2003 28 6 491 498 10.1093/chemse/28.6.491 12907586
42. Effect of miraculin on behavioral and single taste fibers responses in common marmoset, Callithrix jacchus jacchus. V Danilova G Hellekant Z Jin, Chem Senses: 1998; Sarasota FL 1998 550
43. Behavioral and single chorda tympani taste fiber responses in the common marmoset, Callithrix jacchus jacchus. V Danilova G Hellekant R Roberts JM Tinti C Nofre, An NY Acad Sci Olfaction and Taste XII 1998 855 160 164 10.1111/j.1749-6632.1998.tb10559.x
44. The sense of taste in a New World monkey, the common marmoset: recordings from the chorda tympani and glossopharyngeal nerves. V Danilova Y Danilov T Roberts J-M Tinti C Nofre G Hellekant, J Neurophysiol 2002 88 579 594 12163511
45. Sense of taste in a New World monkey, the common marmoset. II. Link between behavior and nerve activity. V Danilova G Hellekant, J Neurophysiol 2004 92 2 1067 1076 10.1152/jn.01183.2003 15071088
46. Elucidating coding of taste qualities with the taste modifier miraculin in the common marmoset. V Danilova G Hellekant, Brain research bulletin 2006 68 5 315 321 10.1016/j.brainresbull.2005.09.008 16377437
47. Human receptors for sweet and umami taste. X Li L Staszewski H Xu K Durick M Zoller E Adler, Proceedings of the National Academy of Sciences of the United States of America 2002 99 7 4692 4696 11917125 10.1073/pnas.072090199
48. Comparative analysis of the T1R taste receptor genes in primates. X Li W Li KJ Mascioli AA Bachmanov MG Tordoff G Epple GK Beauchamp DR Reed, AChems XXV: 2003; Sarasota Fl 2003 74 abstract 296
49. Different functional roles of T1R subunits in the heteromeric taste receptors. H Xu L Staszewski H Tang E Adler M Zoller X Li, Proceedings of the National Academy of Sciences of the United States of America 2004 101 39 14258 14263 15353592 10.1073/pnas.0404384101
50. Lactisole interacts with the transmembrane domains of human T1R3 to inhibit sweet taste. P Jiang M Cui B Zhao Z Liu LA Snyder LM Benard R Osman RF Margolskee M Max, J Biol Chem 2005 280 15 15238 15246 10.1074/jbc.M414287200 15668251
51. T1R3 sequence pers. X Li, Communication to Hellekant G 2008
52. Cypha [propionic acid, 2-(4-methoxyphenol) salt] inhibits sweet taste in humans, but not in rats. A Sclafani C Perez, Physiology & behavior 1997 61 1 25 29 10.1016/S0031-9384(96)00316-2 8976529
53. Valine 738 and lysine 735 in the fifth transmembrane domain of rTas1r3 mediate insensitivity towards lactisole of the rat sweet taste receptor. M Winnig B Bufe W Meyerhof, BMC neuroscience 2005 6 1 22 15817126 10.1186/1471-2202-6-22
54. Renewal of taste bud cells in rat circumvallate papillae. AI Farbman, Cell Tissue Kinet 1980 13 4 349 357 7428010
55. Effects of gymnemic acid on the chorda tympani proper nerve responses to sweet, sour, salty and bitter taste stimuli in the chimpanzee. G Hellekant CH Segerstad T Roberts H van der Wel JN Brouwer D Glaser R Haynes JW Eichberg, Acta Physiology Scand 1985 124 3 399 408 10.1111/j.1748-1716.1985.tb07675.x
56. Specific taste sensitivity of single chorda tympani fibers in chimpanzee. Y Ninomiya G Hellekant, Proc Jpn Symp Taste and Smell 1991 313 316
57. "Type III" cells of rat taste buds: immunohistochemical and ultrastructural studies of neuron-specific enolase, protein gene product 9.5, and serotonin. CL Yee R Yang B Bottger TE Finger JC Kinnamon, The Journal of comparative neurology 2001 440 1 97 108 10.1002/cne.1372 11745610
58. Morphologic characterization of rat taste receptor cells that express components of the phospholipase C signaling pathway. TR Clapp R Yang CL Stoick SC Kinnamon JC Kinnamon, The Journal of comparative neurology 2004 468 3 311 321 10.1002/cne.10963 14681927
59. Synaptobrevin-2-like immunoreactivity is associated with vesicles at synapses in rat circumvallate taste buds. R Yang CL Stoick JC Kinnamon, The Journal of comparative neurology 2004 471 1 59 71 10.1002/cne.20021 14983476
60. Structure of taste buds in foliate papillae of the rhesus monkey, Macaca mulatta. AI Farbman G Hellekant A Nelson, American Journal of Anatomy 1985 172 1 41 56 10.1002/aja.1001720104 3969929
61. Ultrastructure of mouse vallate taste buds. I. Taste cells and their associated synapses. JC Kinnamon BJ Taylor RJ Delay SD Roper, Journal of Comparative Neurology 1985 235 1 48 60 10.1002/cne.902350105 3989005
62. Ultrastructure of mouse vallate taste buds: II. Cell types and cell lineage. RJ Delay JC Kinnamon SD Roper, Journal of Comparative Neurology 1986 253 2 242 252 10.1002/cne.902530210 3793992
63. Ultrastructure of Mouse Fungiform Taste Buds. DM Henzler JC Kinnamon, Olfaction and Taste 1987 IX 359 361
64. Interactions between Taste Cells and Nerve Fibers in Murine Foliate Taste Buds. SM Royer JC Kinnamon, Olfaction and Taste 1987 IX 577 579
65. Ultrastructure of mouse vallate taste buds: III. Patterns of synaptic connectivity. JC Kinnamon TA Sherman SD Roper, Journal of Comparative Neurology 1988 270 1 1 10 10.1002/cne.902700102 3372731
66. Ultrastructure of mouse foliate taste buds: synaptic and nonsynaptic interactions between taste cells and nerve fibers. SM Royer JC Kinnamon, Journal of Comparative Neurology 1988 270 1 11 24 10.1002/cne.902700103 3372732
67. HVEM ultrastructural analysis of mouse fungiform taste buds, cell types, and associated synapses. JC Kinnamon DM Henzler SM Royer, Microscopy Research and Technique 1993 26 142 156 10.1002/jemt.1070260207
68. Electrophysiological and morphological properties of light and dark cells isolated from mudpuppy taste buds. M McPheeters AJ Barber SC Kinnamon JC Kinnamon, The Journal of comparative neurology 1994 346 4 601 612 10.1002/cne.903460411 7983246
69. Application of serial sectioning and three-dimensional reconstruction to the study of taste bud ultrastructure and organization. SM Royer JC Kinnamon, Microsc Res Tech 1994 29 5 381 407 10.1002/jemt.1070290508 7858318
70. Taste cells with synapses in rat circumvallate papillae display SNAP-25-like immunoreactivity. R Yang HH Crowley ME Rock JC Kinnamon, The Journal of comparative neurology 2000 424 2 205 215 10.1002/1096-9861(20000821) 424:2<205::AID-CNE23.0.CO;2-F 10906698
71. The role of pannexin 1 hemichannels in ATP release and cell-cell communication in mouse taste buds. YJ Huang Y Maruyama G Dvoryanchikov E Pereira N Chaudhari SD Roper, Proceedings of the National Academy of Sciences of the United States of America 2007 104 15 6436 6441 17389364 10.1073/pnas.0611280104
72. Signal transduction and information processing in mammalian taste buds. SD Roper, Pflugers Arch 2007 454 5 759 776 10.1007/s00424-007-0247-x 17468883
73. Breadth of tuning and taste coding in mammalian taste buds. SM Tomchik S Berg JW Kim N Chaudhari SD Roper, J Neurosci 2007 27 40 10840 10848 10.1523/JNEUROSCI.1863-07.2007 17913917
74. ATP signaling is crucial for communication from taste buds to gustatory nerves. TE Finger V Danilova J Barrows DL Bartel AJ Vigers L Stone G Hellekant SC Kinnamon, Science 2005 310 5753 1495 1499 16322458 10.1126/science.1118435
75. Taste signal transmission from fungiform taste bud cells to chorda tympani nerve fibers in mice. R Yoshida Y Murata T Yasuo K Yasumatsu N Shigemura Y Ninomiya, ECRO 2008 Portoroz Slovenia: University of Ljubljana and Slovenian Physiological Society 2008
76. Coding channels for taste perception: information transmission from taste cells to gustatory nerve fibers. R Yoshida K Yasumatsu N Shigemura Y Ninomiya, Archives of histology and cytology 2006 69 4 233 242 10.1679/aohc.69.233
77. Single neurons in the nucleus of the solitary tract respond selectively to bitter taste stimuli. LC Geran SP Travers, J Neurophysiol 2006 96 5 2513 2527 10.1152/jn.00607.2006 16899635
78. Vasoactive intestinal peptide-like immunoreactivity in rodent taste cells. MS Herness, Neuroscience 1989 33 2 411 419 10.1016/0306-4522(89)90220-0 2622534
79. A paracrine signaling role for serotonin in rat taste buds: expression and localization of serotonin receptor subtypes. N Kaya T Shen SG Lu FL Zhao S Herness, American journal of physiology 2004 286 4 R649 658 14715493
80. Mouse taste buds use serotonin as a neurotransmitter. YJ Huang Y Maruyama KS Lu E Pereira I Plonsky JE Baur D Wu SD Roper, J Neurosci 2005 25 4 843 847 10.1523/JNEUROSCI.4446-04.2005 15673664
81. Co-expression patterns of the neuropeptides vasoactive intestinal peptide and cholecystokinin with the transduction molecules alpha-gustducin and T1R2 in rat taste receptor cells. T Shen N Kaya FL Zhao SG Lu Y Cao S Herness, Neuroscience 2005 130 1 229 238 10.1016/j.neuroscience.2004.09.017 15561439