-
1
-
-
0004202923
-
-
National Institutes of Health, NIH publ, Bethesda No. 95-1468
-
La Porte R.E., Matsushima M., and Chang Y.F. Prevalence and incidence of insulin-dependant diabetes. 2nd Edition (1995), National Institutes of Health, NIH publ, Bethesda No. 95-1468
-
(1995)
Prevalence and incidence of insulin-dependant diabetes. 2nd Edition
-
-
La Porte, R.E.1
Matsushima, M.2
Chang, Y.F.3
-
2
-
-
0033429304
-
World wide increase in the incidence of Type 1 diabetes-analysis of the data on published incidence trends
-
Onkamo P., Vaananen S., Karvonen M., et al. World wide increase in the incidence of Type 1 diabetes-analysis of the data on published incidence trends. Diabetologia 42 (1999) 1395-1403
-
(1999)
Diabetologia
, vol.42
, pp. 1395-1403
-
-
Onkamo, P.1
Vaananen, S.2
Karvonen, M.3
-
3
-
-
0033744232
-
Analysis of 20 years of prospective registration of childhood onset diabetes time trends and birth cohort effects. Swedish Childhood Study Group
-
Dahlquist G., and Mustonen L. Analysis of 20 years of prospective registration of childhood onset diabetes time trends and birth cohort effects. Swedish Childhood Study Group. Acta Paediatr 89 (2000) 1231-1237
-
(2000)
Acta Paediatr
, vol.89
, pp. 1231-1237
-
-
Dahlquist, G.1
Mustonen, L.2
-
4
-
-
0036580691
-
The incidence of type 1 diabetes in the age group 0-39 years has not increased in Antwerp (Belgium) between 1989 and 2000
-
Weet I., De Leeuw I.H., Du Caju M.V., et al. The incidence of type 1 diabetes in the age group 0-39 years has not increased in Antwerp (Belgium) between 1989 and 2000. Diabetes Care 25 (2002) 840-846
-
(2002)
Diabetes Care
, vol.25
, pp. 840-846
-
-
Weet, I.1
De Leeuw, I.H.2
Du Caju, M.V.3
-
5
-
-
0003514452
-
-
Available at:
-
World Health Organization. Available at: (Accessed December 1, 2008). http://www.who.int/en
-
(2008)
World Health Organization
-
-
-
6
-
-
21244454753
-
ADA Outstanding Scientific Achievement Lecture 2004. Thirty years of investigating the autoimmune basis for type 1 diabetes: why can't we prevent or reverse this disease?
-
Atkinson M.A. ADA Outstanding Scientific Achievement Lecture 2004. Thirty years of investigating the autoimmune basis for type 1 diabetes: why can't we prevent or reverse this disease?. Diabetes 54 (2005) 1253-1263
-
(2005)
Diabetes
, vol.54
, pp. 1253-1263
-
-
Atkinson, M.A.1
-
7
-
-
10744229777
-
Insulin secretion in type 1 diabetes
-
Steele C., Hagopian W.A., Gitelman S., et al. Insulin secretion in type 1 diabetes. Diabetes 53 2 (2004) 426-433
-
(2004)
Diabetes
, vol.53
, Issue.2
, pp. 426-433
-
-
Steele, C.1
Hagopian, W.A.2
Gitelman, S.3
-
8
-
-
0031423760
-
The nonobese diabetic mouse as a model of autoimmune diabetes: immune dysregulation gets the NOD
-
Delovitch T.L., and Singh B. The nonobese diabetic mouse as a model of autoimmune diabetes: immune dysregulation gets the NOD. Immunity 7 6 (1997) 727-738
-
(1997)
Immunity
, vol.7
, Issue.6
, pp. 727-738
-
-
Delovitch, T.L.1
Singh, B.2
-
9
-
-
0035061420
-
The regulatory role of DR4 in a spontaneous diabetes DQ8 transgenic model
-
Wen L., Chen N.Y., Tang J., et al. The regulatory role of DR4 in a spontaneous diabetes DQ8 transgenic model. J Clin Invest 107 7 (2001) 871-880
-
(2001)
J Clin Invest
, vol.107
, Issue.7
, pp. 871-880
-
-
Wen, L.1
Chen, N.Y.2
Tang, J.3
-
10
-
-
16244371700
-
Human leukocyte antigen-DQ8 transgenic mice: a model to examine the toxicity of aerosolized staphylococcal enterotoxin B
-
Roy C.J., Warfield K.L., Welcher B.C., et al. Human leukocyte antigen-DQ8 transgenic mice: a model to examine the toxicity of aerosolized staphylococcal enterotoxin B. Infect Immun 73 4 (2005) 2452-2460
-
(2005)
Infect Immun
, vol.73
, Issue.4
, pp. 2452-2460
-
-
Roy, C.J.1
Warfield, K.L.2
Welcher, B.C.3
-
11
-
-
0028006398
-
Beta 2-microglobulin-deficient NOD mice do not develop insulitis or diabetes
-
Wicker L.S., Leiter E.H., Todd J.A., et al. Beta 2-microglobulin-deficient NOD mice do not develop insulitis or diabetes. Diabetes 43 3 (1994) 500-504
-
(1994)
Diabetes
, vol.43
, Issue.3
, pp. 500-504
-
-
Wicker, L.S.1
Leiter, E.H.2
Todd, J.A.3
-
12
-
-
0942264435
-
The role of B lymphocytes as key antigen-presenting cells in the development of T cell-mediated autoimmune type 1 diabetes
-
Serreze D.V., and Silveira P.A. The role of B lymphocytes as key antigen-presenting cells in the development of T cell-mediated autoimmune type 1 diabetes. Curr Dir Autoimmun 6 (2003) 212-227
-
(2003)
Curr Dir Autoimmun
, vol.6
, pp. 212-227
-
-
Serreze, D.V.1
Silveira, P.A.2
-
13
-
-
0025951776
-
Insulitis in type 1 (insulin-dependent) diabetes mellitus in man-macrophages, lymphocytes, and interferon-gamma containing cells
-
Foulis A.K., McGill M., and Farquharson M.A. Insulitis in type 1 (insulin-dependent) diabetes mellitus in man-macrophages, lymphocytes, and interferon-gamma containing cells. J Pathol 165 2 (1991) 97-103
-
(1991)
J Pathol
, vol.165
, Issue.2
, pp. 97-103
-
-
Foulis, A.K.1
McGill, M.2
Farquharson, M.A.3
-
14
-
-
0027361654
-
Mononuclear cell infiltration and its relation to the expression of major histocompatibility complex antigens and adhesion molecules in pancreas biopsy specimens from newly diagnosed insulin-dependent diabetes mellitus patients
-
Itoh N., Hanafusa T., Miyazaki A., et al. Mononuclear cell infiltration and its relation to the expression of major histocompatibility complex antigens and adhesion molecules in pancreas biopsy specimens from newly diagnosed insulin-dependent diabetes mellitus patients. J Clin Invest 92 (1993) 2313-2322
-
(1993)
J Clin Invest
, vol.92
, pp. 2313-2322
-
-
Itoh, N.1
Hanafusa, T.2
Miyazaki, A.3
-
15
-
-
34247627376
-
Coxsackie B4 virus infection of beta cells and natural killer cell insulitis in recent-onset type 1 diabetic patients
-
Dotta F., Censini S., van Halteren A.G., et al. Coxsackie B4 virus infection of beta cells and natural killer cell insulitis in recent-onset type 1 diabetic patients. Proc Natl Acad Sci U S A 104 12 (2007) 5115-5120
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, Issue.12
, pp. 5115-5120
-
-
Dotta, F.1
Censini, S.2
van Halteren, A.G.3
-
16
-
-
13144265739
-
Genome-wide association studies: theoretical and practical concerns
-
Wang W.Y., Barratt B.J., Clayton D.G., et al. Genome-wide association studies: theoretical and practical concerns. Nat Rev Genet 6 2 (2005) 109-118
-
(2005)
Nat Rev Genet
, vol.6
, Issue.2
, pp. 109-118
-
-
Wang, W.Y.1
Barratt, B.J.2
Clayton, D.G.3
-
17
-
-
34347341846
-
Robust associations of four new chromosome regions from genome-wide analyses of type 1 diabetes
-
Todd J.A., Walker N.M., Cooper J.D., et al. Robust associations of four new chromosome regions from genome-wide analyses of type 1 diabetes. Nat Genet 39 7 (2007) 857-864
-
(2007)
Nat Genet
, vol.39
, Issue.7
, pp. 857-864
-
-
Todd, J.A.1
Walker, N.M.2
Cooper, J.D.3
-
18
-
-
18744385526
-
Expanded T cells from pancreatic lymph nodes of type 1 diabetic subjects recognize the insulin epitope
-
Kent S.C., Chen Y., Bregoli L., et al. Expanded T cells from pancreatic lymph nodes of type 1 diabetic subjects recognize the insulin epitope. Nature 435 (2005) 224-228
-
(2005)
Nature
, vol.435
, pp. 224-228
-
-
Kent, S.C.1
Chen, Y.2
Bregoli, L.3
-
19
-
-
27744524215
-
The insulin A-chain epitope recognized by human T cells is post translationally modified
-
Mannering S.I., Harrison L.C., Williamson N.A., et al. The insulin A-chain epitope recognized by human T cells is post translationally modified. J Exp Med 202 (2005) 1191-1197
-
(2005)
J Exp Med
, vol.202
, pp. 1191-1197
-
-
Mannering, S.I.1
Harrison, L.C.2
Williamson, N.A.3
-
20
-
-
18744366947
-
Prime role for an insulin epitope in the development of type 1 diabetes in NOD mice
-
Nakayama M., Abiru N., Moriyama H., et al. Prime role for an insulin epitope in the development of type 1 diabetes in NOD mice. Nature 435 7039 (2005) 220-223
-
(2005)
Nature
, vol.435
, Issue.7039
, pp. 220-223
-
-
Nakayama, M.1
Abiru, N.2
Moriyama, H.3
-
21
-
-
34247101086
-
Cellular and molecular pathogenesis of type 1A diabetes
-
Jahromi M.M., and Eisenbarth G.S. Cellular and molecular pathogenesis of type 1A diabetes. Cell Mol Life Sci 64 (2007) 865-872
-
(2007)
Cell Mol Life Sci
, vol.64
, pp. 865-872
-
-
Jahromi, M.M.1
Eisenbarth, G.S.2
-
22
-
-
44449148889
-
Autoimmunity to both proinsulin and IGRP is required for diabetes in nonobese diabetic 8.3 TCR transgenic mice
-
Krishnamurthy B., Mariana L., Gellert S.A., et al. Autoimmunity to both proinsulin and IGRP is required for diabetes in nonobese diabetic 8.3 TCR transgenic mice. J Immunol 180 7 (2008) 4458-4464
-
(2008)
J Immunol
, vol.180
, Issue.7
, pp. 4458-4464
-
-
Krishnamurthy, B.1
Mariana, L.2
Gellert, S.A.3
-
23
-
-
40249120466
-
Standards of medical care in diabetes-2008
-
American Diabetes Association. Standards of medical care in diabetes-2008. Diabetes Care 31 (2008) S12-S54
-
(2008)
Diabetes Care
, vol.31
-
-
American Diabetes Association1
-
24
-
-
0027370108
-
The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus
-
Diabetes Control and Complications Trial Research Group. The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus. N Engl J Med 329 (1993) 977-986
-
(1993)
N Engl J Med
, vol.329
, pp. 977-986
-
-
Diabetes Control and Complications Trial Research Group1
-
25
-
-
0038323914
-
Regression of microalbuminuria in type 1 diabetes
-
Perkin B.A., Ficocrello L.H., Silva K.H., et al. Regression of microalbuminuria in type 1 diabetes. N Engl J Med 348 (2003) 2085-2093
-
(2003)
N Engl J Med
, vol.348
, pp. 2085-2093
-
-
Perkin, B.A.1
Ficocrello, L.H.2
Silva, K.H.3
-
26
-
-
0031006603
-
Hypoglycemia in the Diabetes Control and Complications Trial
-
Diabetes Control and Complications Trial Research Group. Hypoglycemia in the Diabetes Control and Complications Trial. Diabetes 46 2 (1997) 271-286
-
(1997)
Diabetes
, vol.46
, Issue.2
, pp. 271-286
-
-
Diabetes Control and Complications Trial Research Group1
-
27
-
-
0032496876
-
Effect of excessive weight gain with insulin therapy of type 1 diabetes on lipid levels and blood pressure: results from the DCCT. The Diabetes Control and Complications Trial
-
Purnell J.Q., Hokanson J.E., Marcovina S.M., et al. Effect of excessive weight gain with insulin therapy of type 1 diabetes on lipid levels and blood pressure: results from the DCCT. The Diabetes Control and Complications Trial. JAMA 280 (1998) 140-146
-
(1998)
JAMA
, vol.280
, pp. 140-146
-
-
Purnell, J.Q.1
Hokanson, J.E.2
Marcovina, S.M.3
-
28
-
-
0035514022
-
Limitations of conventional methods of self monitoring of blood glucose: lessons learned from three days of continuous glucose sensing in paediatric patients with type 1 diabetes
-
Boland E., Monsod T., Delucia M., et al. Limitations of conventional methods of self monitoring of blood glucose: lessons learned from three days of continuous glucose sensing in paediatric patients with type 1 diabetes. Diabetes Care 24 11 (2001) 1858-1862
-
(2001)
Diabetes Care
, vol.24
, Issue.11
, pp. 1858-1862
-
-
Boland, E.1
Monsod, T.2
Delucia, M.3
-
29
-
-
0036085788
-
Type IA diabetes mellitus-associated autoimmunity
-
vii-viii
-
Liu E., and Eisenbarth G.S. Type IA diabetes mellitus-associated autoimmunity. Endocrinol Metab Clin North Am 31 (2002) 391-410 vii-viii
-
(2002)
Endocrinol Metab Clin North Am
, vol.31
, pp. 391-410
-
-
Liu, E.1
Eisenbarth, G.S.2
-
30
-
-
56249130403
-
Towards a curative therapy in type 1 diabetes: remission of autoimmunity, maintenance and augmentation of β cell mass. 2007 Defining Optimal Immunotherapies for Type 1 Diabetes
-
Waldron-Lynch F., von Herrath M., and Herold K.C. Towards a curative therapy in type 1 diabetes: remission of autoimmunity, maintenance and augmentation of β cell mass. 2007 Defining Optimal Immunotherapies for Type 1 Diabetes. Novartis Found Symp 292 (2009) 146-155
-
(2009)
Novartis Found Symp
, vol.292
, pp. 146-155
-
-
Waldron-Lynch, F.1
von Herrath, M.2
Herold, K.C.3
-
31
-
-
34848894301
-
Rational development of antigen-specific therapies for type 1 diabetes
-
Fousteri G., Bresson, and von Herrath M. Rational development of antigen-specific therapies for type 1 diabetes. Adv Exp Med Biol 601 (2007) 313-319
-
(2007)
Adv Exp Med Biol
, vol.601
, pp. 313-319
-
-
Fousteri, G.1
Bresson, von Herrath, M.2
-
32
-
-
10744226541
-
Regulatory T cells and dendritic cells in transplantation tolerance: molecular markers and mechanisms
-
Cobbold S.P., Nolan K.F., Graca L., et al. Regulatory T cells and dendritic cells in transplantation tolerance: molecular markers and mechanisms. Immunol Rev 196 (2003) 109-124
-
(2003)
Immunol Rev
, vol.196
, pp. 109-124
-
-
Cobbold, S.P.1
Nolan, K.F.2
Graca, L.3
-
33
-
-
34047097525
-
New reagents on the horizon for immune tolerance
-
St. Clair E.M., Turka L.A., Saxon A., et al. New reagents on the horizon for immune tolerance. Annu Rev Med 58 (2007) 329-346
-
(2007)
Annu Rev Med
, vol.58
, pp. 329-346
-
-
St. Clair, E.M.1
Turka, L.A.2
Saxon, A.3
-
34
-
-
14644388075
-
Dominant tolerance: activation thresholds for peripheral generation of regulatory T cells
-
Graca L., Chen T.C., Le Moine A., et al. Dominant tolerance: activation thresholds for peripheral generation of regulatory T cells. Trends Immunol 26 (2005) 131-135
-
(2005)
Trends Immunol
, vol.26
, pp. 131-135
-
-
Graca, L.1
Chen, T.C.2
Le Moine, A.3
-
35
-
-
34447542181
-
Type 1 diabetes intervention trials 2007: where are we and where are we going?
-
Haller M.J., Gottieb P.A., and Schatz D.A. Type 1 diabetes intervention trials 2007: where are we and where are we going?. Curr Opin Endocrinol Diabetes Obes 14 (2007) 283-287
-
(2007)
Curr Opin Endocrinol Diabetes Obes
, vol.14
, pp. 283-287
-
-
Haller, M.J.1
Gottieb, P.A.2
Schatz, D.A.3
-
36
-
-
34249032122
-
Are insights gained from NOD mice sufficient to guide clinical translation?
-
Roep B.O. Are insights gained from NOD mice sufficient to guide clinical translation?. Ann N Y Acad Sci 1103 (2007) 1-10
-
(2007)
Ann N Y Acad Sci
, vol.1103
, pp. 1-10
-
-
Roep, B.O.1
-
37
-
-
0027480065
-
Insulin prophylaxis in individuals at high risk of type 1 diabetes
-
Keller R.J., Eisenbarth G.S., and Jackson R.A. Insulin prophylaxis in individuals at high risk of type 1 diabetes. Lancet 341 (1993) 927-928
-
(1993)
Lancet
, vol.341
, pp. 927-928
-
-
Keller, R.J.1
Eisenbarth, G.S.2
Jackson, R.A.3
-
38
-
-
0031976734
-
Delay of type 1 diabetes in high risk, first degree relatives by parental antigen administration: the Schwabling Insulin Prophylaxis Pilot Trial
-
Fuchtenbusch M., Rabl W., Grassi B., et al. Delay of type 1 diabetes in high risk, first degree relatives by parental antigen administration: the Schwabling Insulin Prophylaxis Pilot Trial. Diabetologia 41 (1998) 536-541
-
(1998)
Diabetologia
, vol.41
, pp. 536-541
-
-
Fuchtenbusch, M.1
Rabl, W.2
Grassi, B.3
-
39
-
-
18144391496
-
Effects of oral insulin in relatives of patients with type 1 diabetes. Diabetes Prevention Trial-Type 1
-
Skyler J.S., Krischer J.P., Wolfsorf J., et al. Effects of oral insulin in relatives of patients with type 1 diabetes. Diabetes Prevention Trial-Type 1. Diabetes Care 28 (2005) 1068-1076
-
(2005)
Diabetes Care
, vol.28
, pp. 1068-1076
-
-
Skyler, J.S.1
Krischer, J.P.2
Wolfsorf, J.3
-
40
-
-
62749127388
-
-
Available at: Accessed December 1, 2008
-
Available at:. http://www.diabetestrialnet.org Accessed December 1, 2008
-
-
-
-
41
-
-
4644230843
-
Pancreatic beta-cell function and immune responses to insulin after administration of intranasal insulin to humans at risk for type 1 diabetes
-
Harrison L.C., Honeyman M.C., Steele C.E., et al. Pancreatic beta-cell function and immune responses to insulin after administration of intranasal insulin to humans at risk for type 1 diabetes. Diabetes Care 27 10 (2004) 2348-2355
-
(2004)
Diabetes Care
, vol.27
, Issue.10
, pp. 2348-2355
-
-
Harrison, L.C.1
Honeyman, M.C.2
Steele, C.E.3
-
42
-
-
62749162748
-
-
Available at: Accessed December 1, 2008
-
Available at:. http://www.thegeorgeinstitute.org Accessed December 1, 2008
-
-
-
-
43
-
-
0036498093
-
Antibiodies against different epitopes of heat shock protein 60 in children with type 1 diabetes mellitus
-
Horvath L., Cervenak L., Orosazlan M., et al. Antibiodies against different epitopes of heat shock protein 60 in children with type 1 diabetes mellitus. Immunol Lett 80 3 (2002) 155-162
-
(2002)
Immunol Lett
, vol.80
, Issue.3
, pp. 155-162
-
-
Horvath, L.1
Cervenak, L.2
Orosazlan, M.3
-
44
-
-
0026699473
-
Secretory granule autoantigen in insulin-dependent diabetes mellitus is related to 62 kDa heat-shock protein (hsp60)
-
Brudzynski K., Martinez V., and Gupta R.S. Secretory granule autoantigen in insulin-dependent diabetes mellitus is related to 62 kDa heat-shock protein (hsp60). J Autoimmun 5 4 (1992) 453-463
-
(1992)
J Autoimmun
, vol.5
, Issue.4
, pp. 453-463
-
-
Brudzynski, K.1
Martinez, V.2
Gupta, R.S.3
-
45
-
-
0036035624
-
Peptide therapy for type 1 diabetes: the immunological homunculus and the rational for vaccination
-
Cohen I.R. Peptide therapy for type 1 diabetes: the immunological homunculus and the rational for vaccination. Diabetologia 45 (2002) 1468-1474
-
(2002)
Diabetologia
, vol.45
, pp. 1468-1474
-
-
Cohen, I.R.1
-
46
-
-
4143123430
-
Neonatal administration of DiaPep277 combined with hydrolysed casein diet, protects against Type 1 diabetes in BB-DP rat. An experimental study
-
Brugman S., Klatter F.A., Visser J., et al. Neonatal administration of DiaPep277 combined with hydrolysed casein diet, protects against Type 1 diabetes in BB-DP rat. An experimental study. Diabetologia 47 7 (2004) 1331-1333
-
(2004)
Diabetologia
, vol.47
, Issue.7
, pp. 1331-1333
-
-
Brugman, S.1
Klatter, F.A.2
Visser, J.3
-
47
-
-
14844347311
-
Heat shock protein 60 inhibits Th1-mediated hepatitis model via innate regulation of Th1/Th2 transcription factors and cytokines
-
Zanin-Zhorov A., Bruck R., Tal G., et al. Heat shock protein 60 inhibits Th1-mediated hepatitis model via innate regulation of Th1/Th2 transcription factors and cytokines. J Immunol 174 6 (2005) 3227-3236
-
(2005)
J Immunol
, vol.174
, Issue.6
, pp. 3227-3236
-
-
Zanin-Zhorov, A.1
Bruck, R.2
Tal, G.3
-
48
-
-
33748988721
-
Peptide p277 of HSP60 signals T cells: inhibition of inflammatory chemotaxis
-
Nussbaum G., Zanin-Zhorov A., Quintana F., et al. Peptide p277 of HSP60 signals T cells: inhibition of inflammatory chemotaxis. Int Immunol 18 (2006) 1413-1419
-
(2006)
Int Immunol
, vol.18
, pp. 1413-1419
-
-
Nussbaum, G.1
Zanin-Zhorov, A.2
Quintana, F.3
-
49
-
-
0035944844
-
Beta cell function in new-onset type 1 diabetes and immunomodulation with heat-shock protein peptide (DiaPep277): a randomised, double-blind, phase II trial
-
Raz I., Elias D., Avron A., et al. Beta cell function in new-onset type 1 diabetes and immunomodulation with heat-shock protein peptide (DiaPep277): a randomised, double-blind, phase II trial. Lancet 358 (2001) 1749-1753
-
(2001)
Lancet
, vol.358
, pp. 1749-1753
-
-
Raz, I.1
Elias, D.2
Avron, A.3
-
50
-
-
34249812097
-
Treatment of new-onset type 1 diabetes with peptide DiaPep277 is safe and associated with preserved beta-cell function: extension of a randomised, double-blind, phase II trial
-
Elias D., Raz I., Avron A., et al. Treatment of new-onset type 1 diabetes with peptide DiaPep277 is safe and associated with preserved beta-cell function: extension of a randomised, double-blind, phase II trial. Diabetes Metab Res Rev 23 (2007) 292-298
-
(2007)
Diabetes Metab Res Rev
, vol.23
, pp. 292-298
-
-
Elias, D.1
Raz, I.2
Avron, A.3
-
51
-
-
34249825219
-
Therapy with the hsp60 peptide DiaPep277 in C-peptide positive type 1 diabetes patients
-
Roep B., Huurman V., Decochez K., et al. Therapy with the hsp60 peptide DiaPep277 in C-peptide positive type 1 diabetes patients. Diabetes Metab Res Rev 23 (2007) 269-275
-
(2007)
Diabetes Metab Res Rev
, vol.23
, pp. 269-275
-
-
Roep, B.1
Huurman, V.2
Decochez, K.3
-
52
-
-
34249786263
-
Effect of heat shock protein peptide DiaPep277 on β-cell function in paediatric and adult patients with recent-onset diabetes mellitus type 1: two prospective, randomised, double blind phase II trials
-
Schloot N., Meierhoff G., Lengyel C., et al. Effect of heat shock protein peptide DiaPep277 on β-cell function in paediatric and adult patients with recent-onset diabetes mellitus type 1: two prospective, randomised, double blind phase II trials. Diabetes Metab Res Rev 23 (2007) 276-285
-
(2007)
Diabetes Metab Res Rev
, vol.23
, pp. 276-285
-
-
Schloot, N.1
Meierhoff, G.2
Lengyel, C.3
-
53
-
-
34249820806
-
Heat-shock protein peptide DiaPep277 treatment in children with newly diagnosed type 1 diabetes: a randomised, double-blind phase II study
-
Lazar L., Ofan R., Weintrob N., et al. Heat-shock protein peptide DiaPep277 treatment in children with newly diagnosed type 1 diabetes: a randomised, double-blind phase II study. Diabetes Metab Res Rev 23 (2007) 286-291
-
(2007)
Diabetes Metab Res Rev
, vol.23
, pp. 286-291
-
-
Lazar, L.1
Ofan, R.2
Weintrob, N.3
-
54
-
-
0025039679
-
Identification of the 64K autoantigen in insulin-dependent diabetes as the GABA-synthesizing enzyme glutamic acid decarboxylase
-
Baekkeskov S., Aanstoot H.J., Christgau S., et al. Identification of the 64K autoantigen in insulin-dependent diabetes as the GABA-synthesizing enzyme glutamic acid decarboxylase. Nature 347 (1990) 151-156
-
(1990)
Nature
, vol.347
, pp. 151-156
-
-
Baekkeskov, S.1
Aanstoot, H.J.2
Christgau, S.3
-
55
-
-
27844561478
-
GAD65 and proinsulin-specific CD4 + T cells detected by MHC class II tetramers in peripheral blood of type 1 diabetes patients and at-risk subjects
-
Oling V., Marttila J., Ilonen J., et al. GAD65 and proinsulin-specific CD4 + T cells detected by MHC class II tetramers in peripheral blood of type 1 diabetes patients and at-risk subjects. J Autoimmun 25 (2005) 235-243
-
(2005)
J Autoimmun
, vol.25
, pp. 235-243
-
-
Oling, V.1
Marttila, J.2
Ilonen, J.3
-
56
-
-
0029923430
-
Nasal administration of glutamate decarboxylase (GAD65) peptides induces Th2 responses and prevents murine insulin-dependent diabetes
-
Tian J., Atkinson M.A., Clare-Salzler M., et al. Nasal administration of glutamate decarboxylase (GAD65) peptides induces Th2 responses and prevents murine insulin-dependent diabetes. J Exp Med 183 (1996) 1561-1567
-
(1996)
J Exp Med
, vol.183
, pp. 1561-1567
-
-
Tian, J.1
Atkinson, M.A.2
Clare-Salzler, M.3
-
57
-
-
16144361909
-
Modulating autoimmune responses to GAD inhibits disease progression and prolongs islet graft survival in diabetes-prone mice
-
Tian J., Clare-Salzler M., Herschenfeld A., et al. Modulating autoimmune responses to GAD inhibits disease progression and prolongs islet graft survival in diabetes-prone mice. Nat Med 2 12 (1996) 1348-1353
-
(1996)
Nat Med
, vol.2
, Issue.12
, pp. 1348-1353
-
-
Tian, J.1
Clare-Salzler, M.2
Herschenfeld, A.3
-
58
-
-
21344461521
-
Clinical evidence for the safety of GAD65 immunomodulation in adult-onset autoimmune diabetes
-
Agardh C.D., Cilio C.M., Lethagen A., et al. Clinical evidence for the safety of GAD65 immunomodulation in adult-onset autoimmune diabetes. J Diabet Complications 19 (2005) 238-246
-
(2005)
J Diabet Complications
, vol.19
, pp. 238-246
-
-
Agardh, C.D.1
Cilio, C.M.2
Lethagen, A.3
-
59
-
-
62749134622
-
-
Available at: Accessed December 1, 2008
-
Available at:. http://www.diamyd.com Accessed December 1, 2008
-
-
-
-
60
-
-
0019945886
-
Preventive and therapeutic effects of large-dose nicotinamide injections on diabetes associated with insulitis. An observation in nonobese diabetic (NOD) mice
-
Yamada K., Nonaka K., Hanafusa T., et al. Preventive and therapeutic effects of large-dose nicotinamide injections on diabetes associated with insulitis. An observation in nonobese diabetic (NOD) mice. Diabetes 31 9 (1982) 749-753
-
(1982)
Diabetes
, vol.31
, Issue.9
, pp. 749-753
-
-
Yamada, K.1
Nonaka, K.2
Hanafusa, T.3
-
61
-
-
0025495693
-
Early nicotinamide treatment in the NOD mouse: effects on diabetes and insulitis suppression and autoantibody levels
-
Reddy S., Bibby N.J., and Elliott R.B. Early nicotinamide treatment in the NOD mouse: effects on diabetes and insulitis suppression and autoantibody levels. Diabetes Res 15 (1990) 95-102
-
(1990)
Diabetes Res
, vol.15
, pp. 95-102
-
-
Reddy, S.1
Bibby, N.J.2
Elliott, R.B.3
-
62
-
-
1642277657
-
European Nicotinamide Diabetes Intervention Trial (ENDIT): a randomised controlled trial if intervention before the onset of type 1 diabetes
-
European Nicotinamide Diabetes Intervention Trial (ENDIT) group. European Nicotinamide Diabetes Intervention Trial (ENDIT): a randomised controlled trial if intervention before the onset of type 1 diabetes. Lancet 363 (2004) 925-931
-
(2004)
Lancet
, vol.363
, pp. 925-931
-
-
European Nicotinamide Diabetes Intervention Trial (ENDIT) group1
-
63
-
-
2942703755
-
A randomized trial of nicotinamide and vitamin E in children with recent onset type 1 diabetes (IMDIAB IX)
-
Crino A., Schiaffinin R., Manfrini S., et al. A randomized trial of nicotinamide and vitamin E in children with recent onset type 1 diabetes (IMDIAB IX). Eur J Endocrinol 150 (2004) 719-724
-
(2004)
Eur J Endocrinol
, vol.150
, pp. 719-724
-
-
Crino, A.1
Schiaffinin, R.2
Manfrini, S.3
-
64
-
-
24944438390
-
A two year observational study of nicotinamide and intensive insulin therapy in patients with recent onset type 1 diabetes mellitus
-
Crino A., Schiaffini R., Ciampalini P., et al. A two year observational study of nicotinamide and intensive insulin therapy in patients with recent onset type 1 diabetes mellitus. J Pediatr Endocrinol Metab 18 (2005) 749-754
-
(2005)
J Pediatr Endocrinol Metab
, vol.18
, pp. 749-754
-
-
Crino, A.1
Schiaffini, R.2
Ciampalini, P.3
-
65
-
-
0028069299
-
Randomized trial comparing nicotinamide and nicotinamide plus cyclosporin in recent onset insulin-dependent diabetes (IMDIAB 1). The IMDIAB Study Group
-
Pozzilli P., Visalli N., Boccuni M.L., et al. Randomized trial comparing nicotinamide and nicotinamide plus cyclosporin in recent onset insulin-dependent diabetes (IMDIAB 1). The IMDIAB Study Group. Diabet Med 11 (1994) 98-104
-
(1994)
Diabet Med
, vol.11
, pp. 98-104
-
-
Pozzilli, P.1
Visalli, N.2
Boccuni, M.L.3
-
66
-
-
0021359025
-
Effects of cyclosporine immunosuppression in insulin-dependent diabetes mellitus of recent onset
-
Stiller C.R., Dupre J., Gent M., et al. Effects of cyclosporine immunosuppression in insulin-dependent diabetes mellitus of recent onset. Science 223 4643 (1984) 1362-1367
-
(1984)
Science
, vol.223
, Issue.4643
, pp. 1362-1367
-
-
Stiller, C.R.1
Dupre, J.2
Gent, M.3
-
67
-
-
0023601936
-
Effects of cyclosporine in recent-onset juvenile type 1 diabetes: impact of age and duration of disease
-
Stiller C.R., Dupre J., Gent M., et al. Effects of cyclosporine in recent-onset juvenile type 1 diabetes: impact of age and duration of disease. J Pediatr 111 6 Pt 2 (1987) 1069-1072
-
(1987)
J Pediatr
, vol.111
, Issue.6 PART 2
, pp. 1069-1072
-
-
Stiller, C.R.1
Dupre, J.2
Gent, M.3
-
68
-
-
0023735943
-
Immunosuppression with azathioprine and prednisone in recent-onset insulin-dependent diabetes mellitus
-
Silverstein J., Maclaren N., Riley W., et al. Immunosuppression with azathioprine and prednisone in recent-onset insulin-dependent diabetes mellitus. N Engl J Med 319 10 (1988) 599-604
-
(1988)
N Engl J Med
, vol.319
, Issue.10
, pp. 599-604
-
-
Silverstein, J.1
Maclaren, N.2
Riley, W.3
-
69
-
-
0023849461
-
Factors associated with early remission of type I diabetes in children treated with cyclosporine
-
Bougneres P.F., Carel J.C., Castano L., et al. Factors associated with early remission of type I diabetes in children treated with cyclosporine. N Engl J Med 318 11 (1988) 663-670
-
(1988)
N Engl J Med
, vol.318
, Issue.11
, pp. 663-670
-
-
Bougneres, P.F.1
Carel, J.C.2
Castano, L.3
-
70
-
-
0025049497
-
Limited duration of remission of insulin dependency in children with recent overt type I diabetes treated with low-dose cyclosporin
-
Bougnères P.F., Landais P., Boisson C., et al. Limited duration of remission of insulin dependency in children with recent overt type I diabetes treated with low-dose cyclosporin. Diabetes 39 10 (1990) 1264-1272
-
(1990)
Diabetes
, vol.39
, Issue.10
, pp. 1264-1272
-
-
Bougnères, P.F.1
Landais, P.2
Boisson, C.3
-
71
-
-
0033009588
-
Cyclosporine nephrotoxicity in type 1 diabetic patients. A 7-year follow-up study
-
Parving H.H., Tarnow L., Nielsen F.S., et al. Cyclosporine nephrotoxicity in type 1 diabetic patients. A 7-year follow-up study. Diabetes Care 22 3 (1999) 478-483
-
(1999)
Diabetes Care
, vol.22
, Issue.3
, pp. 478-483
-
-
Parving, H.H.1
Tarnow, L.2
Nielsen, F.S.3
-
72
-
-
0019851727
-
Treatment of acute renal allograft rejection with OKT3 monoclonal antibody
-
Cosimi A.B., Burton R.C., Colvin R.B., et al. Treatment of acute renal allograft rejection with OKT3 monoclonal antibody. Transplantation 32 (1981) 535-539
-
(1981)
Transplantation
, vol.32
, pp. 535-539
-
-
Cosimi, A.B.1
Burton, R.C.2
Colvin, R.B.3
-
73
-
-
62749170532
-
Phase I study of an engineered aglycosylated humanized CD3 antibody in renal transplant rejection
-
Friend P.J., Hale G., Chatenoud L., et al. Phase I study of an engineered aglycosylated humanized CD3 antibody in renal transplant rejection. Transplantation 32 (1981) 535-539
-
(1981)
Transplantation
, vol.32
, pp. 535-539
-
-
Friend, P.J.1
Hale, G.2
Chatenoud, L.3
-
74
-
-
0030896612
-
Nonmitogenic anti-CD3 monoclonal antibodies deliver a partial T cell receptor signal and induce clonal anergy
-
Smith J.A., Tso J.Y., Clark M.R., et al. Nonmitogenic anti-CD3 monoclonal antibodies deliver a partial T cell receptor signal and induce clonal anergy. J Exp Med 185 (1997) 1413-1422
-
(1997)
J Exp Med
, vol.185
, pp. 1413-1422
-
-
Smith, J.A.1
Tso, J.Y.2
Clark, M.R.3
-
75
-
-
0020361983
-
Human in vivo antigenic modulation induced by the anti-T cell OKT3 monoclonal antibody
-
Chatenoud L., Baudrihaye M.F., Kreis H., et al. Human in vivo antigenic modulation induced by the anti-T cell OKT3 monoclonal antibody. Eur J Immunol 12 11 (1982) 979-982
-
(1982)
Eur J Immunol
, vol.12
, Issue.11
, pp. 979-982
-
-
Chatenoud, L.1
Baudrihaye, M.F.2
Kreis, H.3
-
76
-
-
0027958044
-
Anti-CD3 antibody induces long-term remission of overt autoimmunity in nonobese diabetic mice
-
Chatenoud L., Thervet E., Primo J., et al. Anti-CD3 antibody induces long-term remission of overt autoimmunity in nonobese diabetic mice. Proc Natl Acad Sci U S A 91 (1994) 123-127
-
(1994)
Proc Natl Acad Sci U S A
, vol.91
, pp. 123-127
-
-
Chatenoud, L.1
Thervet, E.2
Primo, J.3
-
77
-
-
0031569177
-
CD3 antibody-induced dominant self tolerance in overtly diabetic NOD mice
-
Chatenoud L., Primo J., and Bach J.F. CD3 antibody-induced dominant self tolerance in overtly diabetic NOD mice. J Immunol 158 (1997) 2947-2954
-
(1997)
J Immunol
, vol.158
, pp. 2947-2954
-
-
Chatenoud, L.1
Primo, J.2
Bach, J.F.3
-
78
-
-
0037314237
-
Activation of human T cells by FcR nonbinding anti-CD3 mAb, hOKT3gamma1 (Ala-Ala)
-
Herold K.C., Burton J.B., Francois, et al. Activation of human T cells by FcR nonbinding anti-CD3 mAb, hOKT3gamma1 (Ala-Ala). J Clin Invest 111 (2003) 409-418
-
(2003)
J Clin Invest
, vol.111
, pp. 409-418
-
-
Herold, K.C.1
Burton, J.B.2
Francois3
-
79
-
-
0141796312
-
TGF-beta-dependent mechanisms mediate restoration of self-tolerance induced by antibodies to CD3 in overt autoimmune diabetes
-
Belghith M., Bluestone J.A., Barriot S., et al. TGF-beta-dependent mechanisms mediate restoration of self-tolerance induced by antibodies to CD3 in overt autoimmune diabetes. Nat Med 9 9 (2003) 1202-1208
-
(2003)
Nat Med
, vol.9
, Issue.9
, pp. 1202-1208
-
-
Belghith, M.1
Bluestone, J.A.2
Barriot, S.3
-
80
-
-
26444515022
-
TCR stimulation with modified anti-CD3 mAb expands CD8 T cell population and induces CD8CD25 Tregs
-
Bisikirska B., Colgan J., and Luban J. TCR stimulation with modified anti-CD3 mAb expands CD8 T cell population and induces CD8CD25 Tregs. J Clin Invest 115 10 (2005) 2904-2913
-
(2005)
J Clin Invest
, vol.115
, Issue.10
, pp. 2904-2913
-
-
Bisikirska, B.1
Colgan, J.2
Luban, J.3
-
81
-
-
34547204632
-
Adaptive TCG-β-dependent regulatory T cells control autoimmune diabetes and are a privileged target of anti-CD3 antibody treatment
-
You S., Leforban B., Garcia C., et al. Adaptive TCG-β-dependent regulatory T cells control autoimmune diabetes and are a privileged target of anti-CD3 antibody treatment. Proc Natl Acad Sci U S A 104 (2007) 6335-6340
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, pp. 6335-6340
-
-
You, S.1
Leforban, B.2
Garcia, C.3
-
82
-
-
0037198420
-
Anti-CD3 monoclonal antibody in new-onset type 1 diabetes mellitus
-
Herold K.C., Hagopian W., Auger J.A., et al. Anti-CD3 monoclonal antibody in new-onset type 1 diabetes mellitus. N Engl J Med 346 22 (2002) 1692-1698
-
(2002)
N Engl J Med
, vol.346
, Issue.22
, pp. 1692-1698
-
-
Herold, K.C.1
Hagopian, W.2
Auger, J.A.3
-
83
-
-
20044375937
-
A single course of anti-CD3 monoclonal antibody hOKT3{gamma}1(Ala-Ala) results in improvement in C-peptide responses and clinical parameters for at least 2 years after onset of type 1 diabetes
-
Herold K.C., Gitelman S.E., Masharani U., et al. A single course of anti-CD3 monoclonal antibody hOKT3{gamma}1(Ala-Ala) results in improvement in C-peptide responses and clinical parameters for at least 2 years after onset of type 1 diabetes. Diabetes 54 6 (2005) 1763-1769
-
(2005)
Diabetes
, vol.54
, Issue.6
, pp. 1763-1769
-
-
Herold, K.C.1
Gitelman, S.E.2
Masharani, U.3
-
84
-
-
20544443927
-
Insulin needs after CD3-antibody therapy in new-onset type 1 diabetes
-
Keymeulen B., Vandemeulebroucke E., Ziegler A.G., et al. Insulin needs after CD3-antibody therapy in new-onset type 1 diabetes. N Engl J Med 352 25 (2005) 2598-2608
-
(2005)
N Engl J Med
, vol.352
, Issue.25
, pp. 2598-2608
-
-
Keymeulen, B.1
Vandemeulebroucke, E.2
Ziegler, A.G.3
-
85
-
-
34249012115
-
Autoimmunity and Beta cell regeneration in mouse and human type 1 diabetes: the peace is not enough
-
Ablamunits V., Sherry N.A., Kushner J.A., et al. Autoimmunity and Beta cell regeneration in mouse and human type 1 diabetes: the peace is not enough. Ann N Y Acad Sci 1103 (2007) 19-32
-
(2007)
Ann N Y Acad Sci
, vol.1103
, pp. 19-32
-
-
Ablamunits, V.1
Sherry, N.A.2
Kushner, J.A.3
-
86
-
-
36448978896
-
Type 1 diabetes as a relapsing-remitting disease?
-
Von Herrath M., Sanda S., and Herold K. Type 1 diabetes as a relapsing-remitting disease?. Nat Rev Immunol 7 (2007) 988-994
-
(2007)
Nat Rev Immunol
, vol.7
, pp. 988-994
-
-
Von Herrath, M.1
Sanda, S.2
Herold, K.3
-
87
-
-
34547230077
-
CD3-specfic antibodies: a portal to the treatment of autoimmunity
-
Chatenoud L., and Bluestone J.A. CD3-specfic antibodies: a portal to the treatment of autoimmunity. Nat Rev Immunol 7 (2007) 622-632
-
(2007)
Nat Rev Immunol
, vol.7
, pp. 622-632
-
-
Chatenoud, L.1
Bluestone, J.A.2
-
88
-
-
33646392755
-
Anti-CD3 and nasal proinsulin combination therapy enhances remission from recent-onset autoimmune diabetes by inducing Tregs
-
Bresson D., Togher L., Rodrigo E., et al. Anti-CD3 and nasal proinsulin combination therapy enhances remission from recent-onset autoimmune diabetes by inducing Tregs. J Clin Invest 116 (2006) 1371-1381
-
(2006)
J Clin Invest
, vol.116
, pp. 1371-1381
-
-
Bresson, D.1
Togher, L.2
Rodrigo, E.3
-
89
-
-
36849018546
-
B cell depletion: a novel therapy for autoimmune diabetes?
-
Bour-Jordan H., and Bluestone J.A. B cell depletion: a novel therapy for autoimmune diabetes?. J Clin Invest 117 12 (2007) 3642-3645
-
(2007)
J Clin Invest
, vol.117
, Issue.12
, pp. 3642-3645
-
-
Bour-Jordan, H.1
Bluestone, J.A.2
-
90
-
-
0034457490
-
Perspective: postnatal pancreatic β cell growth
-
1926-9
-
Bonner-Weir S. Perspective: postnatal pancreatic β cell growth. Endocrinology 141 (2000) 1926-9
-
(2000)
Endocrinology
, vol.141
-
-
Bonner-Weir, S.1
-
91
-
-
31844443761
-
The rise and fall of insulin secretion in type 1 diabetes mellitus
-
Tsai E.B., Sherry N.A., Palmer J.P., et al. The rise and fall of insulin secretion in type 1 diabetes mellitus. Diabetologia 49 (2006) 261-270
-
(2006)
Diabetologia
, vol.49
, pp. 261-270
-
-
Tsai, E.B.1
Sherry, N.A.2
Palmer, J.P.3
-
92
-
-
33845523340
-
Effects of autoimmunity and immune therapy on beta-cell turnover in type 1 diabetes
-
Sherry N.A., Kushner J.A., Glandt M., et al. Effects of autoimmunity and immune therapy on beta-cell turnover in type 1 diabetes. Diabetes 55 (2006) 3238-3245
-
(2006)
Diabetes
, vol.55
, pp. 3238-3245
-
-
Sherry, N.A.1
Kushner, J.A.2
Glandt, M.3
-
93
-
-
1842865711
-
Redefining the clinical remission period in children with type 1 diabetes
-
Chase H.P., MacKenzie T.A., Burdick J., et al. Redefining the clinical remission period in children with type 1 diabetes. Pediatr Diabetes 5 1 (2004) 16-19
-
(2004)
Pediatr Diabetes
, vol.5
, Issue.1
, pp. 16-19
-
-
Chase, H.P.1
MacKenzie, T.A.2
Burdick, J.3
-
94
-
-
9144268894
-
C-peptide is the appropriate outcome measure for type 1 diabetes clinical trials to preserve beta-cell function: report of an ADA workshop, 21-22 October 2001
-
Palmer J.P., Fleming G.A., Greenbaum C.J., et al. C-peptide is the appropriate outcome measure for type 1 diabetes clinical trials to preserve beta-cell function: report of an ADA workshop, 21-22 October 2001. Diabetes 53 1 (2004) 250-264
-
(2004)
Diabetes
, vol.53
, Issue.1
, pp. 250-264
-
-
Palmer, J.P.1
Fleming, G.A.2
Greenbaum, C.J.3
-
95
-
-
31844443691
-
Natural history of β-cell function in type 1 diabetes
-
Sherry N.A., Tsai E.B., and Herold K.C. Natural history of β-cell function in type 1 diabetes. Diabetes 54 (2005) S32-S39
-
(2005)
Diabetes
, vol.54
-
-
Sherry, N.A.1
Tsai, E.B.2
Herold, K.C.3
-
96
-
-
0033513455
-
Exendin-4 stimulates both beta-cell replication and neogenesis, resulting in increased beta-cell mass and improved glucose tolerance in diabetic rats
-
Xu G., Stoffers D.A., and Habener J.F. Exendin-4 stimulates both beta-cell replication and neogenesis, resulting in increased beta-cell mass and improved glucose tolerance in diabetic rats. Diabetes 48 12 (1999) 2270-2276
-
(1999)
Diabetes
, vol.48
, Issue.12
, pp. 2270-2276
-
-
Xu, G.1
Stoffers, D.A.2
Habener, J.F.3
-
97
-
-
34547672616
-
Continuous stimulation of human glucagon-like peptide-1 (7-36) amide in a mouse model (NOD) delays the onset of autoimmune type 1 diabetes
-
Zhang J., Tokui Y., Yamagata K., et al. Continuous stimulation of human glucagon-like peptide-1 (7-36) amide in a mouse model (NOD) delays the onset of autoimmune type 1 diabetes. Diabetologia 50 (2007) 1900-1909
-
(2007)
Diabetologia
, vol.50
, pp. 1900-1909
-
-
Zhang, J.1
Tokui, Y.2
Yamagata, K.3
-
98
-
-
22344443114
-
Hyperinsulinemic hypoglycaemia with nesidoblastosis after gastric-bypass surgery
-
Service G.J., Thompson G.B., Service F.J., et al. Hyperinsulinemic hypoglycaemia with nesidoblastosis after gastric-bypass surgery. N Engl J Med 353 (2005) 249-254
-
(2005)
N Engl J Med
, vol.353
, pp. 249-254
-
-
Service, G.J.1
Thompson, G.B.2
Service, F.J.3
-
99
-
-
2942689978
-
Gastric bypass for obesity: mechanisms of weight loss and diabetes resolution
-
Cummings D.E., Overduin J., Foster-Schubert K.E., et al. Gastric bypass for obesity: mechanisms of weight loss and diabetes resolution. J Clin Endocrinol Metab 89 (2004) 2608-2615
-
(2004)
J Clin Endocrinol Metab
, vol.89
, pp. 2608-2615
-
-
Cummings, D.E.1
Overduin, J.2
Foster-Schubert, K.E.3
-
100
-
-
34447267513
-
Efficacy and safety of incretin therapy in type 2 diabetes: systematic review and meta-analysis
-
Amori R.E., Lau J., and Pittas A.G. Efficacy and safety of incretin therapy in type 2 diabetes: systematic review and meta-analysis. JAMA 298 2 (2007) 194-206
-
(2007)
JAMA
, vol.298
, Issue.2
, pp. 194-206
-
-
Amori, R.E.1
Lau, J.2
Pittas, A.G.3
-
101
-
-
3042737844
-
Cure of overt diabetes in NOD mice by transient treatment with anti-lymphocyte serum and exendin-4
-
Ogawa N., List J.F., Habener J.F., et al. Cure of overt diabetes in NOD mice by transient treatment with anti-lymphocyte serum and exendin-4. Diabetes 53 7 (2004) 1700-1705
-
(2004)
Diabetes
, vol.53
, Issue.7
, pp. 1700-1705
-
-
Ogawa, N.1
List, J.F.2
Habener, J.F.3
-
102
-
-
35548999311
-
Exendin-4 improves reversal of diabetes in NOD mice treated with anti-CD3 monoclonal antibody by enhancing recovery of β-cells
-
Sherry N.A., Chen W., Kushner J.A., et al. Exendin-4 improves reversal of diabetes in NOD mice treated with anti-CD3 monoclonal antibody by enhancing recovery of β-cells. Endocrionology 148 (2007) 5138-5144
-
(2007)
Endocrionology
, vol.148
, pp. 5138-5144
-
-
Sherry, N.A.1
Chen, W.2
Kushner, J.A.3
-
104
-
-
34247264408
-
Prediction and prevention of type 1 diabetes: progress, problems, and prospects
-
Skyler J.S. Prediction and prevention of type 1 diabetes: progress, problems, and prospects. Clin Pharmacol Ther 81 (2007) 768-771
-
(2007)
Clin Pharmacol Ther
, vol.81
, pp. 768-771
-
-
Skyler, J.S.1
-
105
-
-
33947726341
-
Moving to efficient therapies in type 1 diabetes: to combine or not to combine
-
Bresson D., and Von Herrath M. Moving to efficient therapies in type 1 diabetes: to combine or not to combine. Autoimmun Rev 6 (2007) 315-322
-
(2007)
Autoimmun Rev
, vol.6
, pp. 315-322
-
-
Bresson, D.1
Von Herrath, M.2
-
106
-
-
33748743615
-
Immune privilege induced by regulatory T cells in transplantation tolerance
-
Cobbold S.P., Adams E., Graca L., et al. Immune privilege induced by regulatory T cells in transplantation tolerance. Immun 213 (2006) 239-255
-
(2006)
Immun
, vol.213
, pp. 239-255
-
-
Cobbold, S.P.1
Adams, E.2
Graca, L.3
-
107
-
-
34848887156
-
Recovery from diabetes in mice β cell regeneration
-
Nir T., Melton D.A., and Dor Y. Recovery from diabetes in mice β cell regeneration. J Clin Invest 117 (2007) 2553-2561
-
(2007)
J Clin Invest
, vol.117
, pp. 2553-2561
-
-
Nir, T.1
Melton, D.A.2
Dor, Y.3
-
108
-
-
34547150491
-
What does the future hold for cell-based tolergenic therapy?
-
Bluestone J.A., Thomson A.W., Shevach E.M., et al. What does the future hold for cell-based tolergenic therapy?. Nat Rev Immunol 7 (2007) 650-654
-
(2007)
Nat Rev Immunol
, vol.7
, pp. 650-654
-
-
Bluestone, J.A.1
Thomson, A.W.2
Shevach, E.M.3
-
109
-
-
33750594322
-
Analysis of T-cell assays to measure autoimmune responses in subjects with type 1 diabetes
-
Seyfert-Margolis V., Gisler T.D., Asare A.L., et al. Analysis of T-cell assays to measure autoimmune responses in subjects with type 1 diabetes. Diabetes 55 (2006) 2588-2594
-
(2006)
Diabetes
, vol.55
, pp. 2588-2594
-
-
Seyfert-Margolis, V.1
Gisler, T.D.2
Asare, A.L.3
-
110
-
-
0037451167
-
Interferon and granulopoiesis signatures in systemic lupus erythematosus blood
-
Bennett L., Palucka A.K., Arce E., et al. Interferon and granulopoiesis signatures in systemic lupus erythematosus blood. J Exp Med 197 6 (2003) 711-723
-
(2003)
J Exp Med
, vol.197
, Issue.6
, pp. 711-723
-
-
Bennett, L.1
Palucka, A.K.2
Arce, E.3
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