-
1
-
-
0035928391
-
Type 1 diabetes: New perspectives on disease pathogenesis and treatment
-
Atkinson, M. & Eisenbarth, G. Type 1 diabetes: new perspectives on disease pathogenesis and treatment. Lancet 358, 221-229 (2001).
-
(2001)
Lancet
, vol.358
, pp. 221-229
-
-
Atkinson, M.1
Eisenbarth, G.2
-
2
-
-
1642443489
-
Type 1 diabetes: Recent developments
-
Devendra, D., Liu, E. & Eisenbarth, G.S. Type 1 diabetes: recent developments. BMJ 328, 750-754 (2004).
-
(2004)
BMJ
, vol.328
, pp. 750-754
-
-
Devendra, D.1
Liu, E.2
Eisenbarth, G.S.3
-
3
-
-
0025141413
-
Quantification of islet-cell antibodies and prediction of insulin-dependent diabetes
-
Bonifacio, E. et al. Quantification of islet-cell antibodies and prediction of insulin-dependent diabetes. Lancet 335, 147-149 (1990).
-
(1990)
Lancet
, vol.335
, pp. 147-149
-
-
Bonifacio, E.1
-
4
-
-
0025011787
-
A prospective study of the development of diabetes in relatives of patients with insulin-dependent diabetes
-
Riley, W.J. et al. A prospective study of the development of diabetes in relatives of patients with insulin-dependent diabetes. N. Engl. J. Med. 323, 1167-1172 (1990).
-
(1990)
N. Engl. J. Med
, vol.323
, pp. 1167-1172
-
-
Riley, W.J.1
-
5
-
-
0029995958
-
Prediction of type I diabetes in first-degree relatives using a combination of insulin GAD, and ICA512bdc/IA-2 autoantibodies
-
Verge, C.F. et al. Prediction of type I diabetes in first-degree relatives using a combination of insulin GAD, and ICA512bdc/IA-2 autoantibodies. Diabetes 45, 926-933 (1996).
-
(1996)
Diabetes
, vol.45
, pp. 926-933
-
-
Verge, C.F.1
-
6
-
-
11844297833
-
Prediction of type 1 diabetes: The natural history of the prediabetic period
-
Eisenbarth, G.S. Prediction of type 1 diabetes: the natural history of the prediabetic period. Adv. Exp. Med. Biol. 552, 268-290 (2004).
-
(2004)
Adv. Exp. Med. Biol
, vol.552
, pp. 268-290
-
-
Eisenbarth, G.S.1
-
7
-
-
0029862542
-
Interactions of age, islet cell antibodies, insulin autoantibodies, and first-phase insulin response in predicting risk of progression to IDDM in ICA+ relatives: The ICARUS data set
-
Bingley, P.J. Interactions of age, islet cell antibodies, insulin autoantibodies, and first-phase insulin response in predicting risk of progression to IDDM in ICA+ relatives: The ICARUS data set. Diabetes 45, 1720-1728 (1996).
-
(1996)
Diabetes
, vol.45
, pp. 1720-1728
-
-
Bingley, P.J.1
-
8
-
-
0035131854
-
-
& The Diabetes Prevention Trial- Type 1 Study Group First phase insulin release during the intravenous glucose tolerance test as a risk factor for type 1 diabetes
-
Chase, H.P., et al. & The Diabetes Prevention Trial- Type 1 Study Group First phase insulin release during the intravenous glucose tolerance test as a risk factor for type 1 diabetes. J. Pediatr. 138, 244-249 (2001).
-
(2001)
J. Pediatr
, vol.138
, pp. 244-249
-
-
Chase, H.P.1
-
9
-
-
33744995996
-
-
& The Diabetes Prevention Trial- Type 1 Study Group Patterns of metabolic progression to type 1 diabetes in the Diabetes Prevention Trial-Type 1
-
Sosenko, J.M., et al. & The Diabetes Prevention Trial- Type 1 Study Group Patterns of metabolic progression to type 1 diabetes in the Diabetes Prevention Trial-Type 1. Diabetes Care 29, 643-649 (2006).
-
(2006)
Diabetes Care
, vol.29
, pp. 643-649
-
-
Sosenko, J.M.1
-
10
-
-
0027455304
-
Can islet cell antibodies predict IDDM in the general population?
-
Bingley, P.J. et al. Can islet cell antibodies predict IDDM in the general population? Diabetes Care 16, 45-50 (1993).
-
(1993)
Diabetes Care
, vol.16
, pp. 45-50
-
-
Bingley, P.J.1
-
11
-
-
23444432369
-
Islet cell antibodies predict insulin-dependent diabetes in United States school age children as powerfully as in unaffected relatives
-
Schatz, D. et al. Islet cell antibodies predict insulin-dependent diabetes in United States school age children as powerfully as in unaffected relatives. J. Clin. Invest. 93, 2403-2407 (1994).
-
(1994)
J. Clin. Invest
, vol.93
, pp. 2403-2407
-
-
Schatz, D.1
-
12
-
-
0028989040
-
HLA-DQB1*0602 is associated with dominant protection from diabetes even among islet cell antibody-positive first-degree relatives of patients with IDDM
-
Pugliese, A. et al. HLA-DQB1*0602 is associated with dominant protection from diabetes even among islet cell antibody-positive first-degree relatives of patients with IDDM. Diabetes 44, 608-613 (1995).
-
(1995)
Diabetes
, vol.44
, pp. 608-613
-
-
Pugliese, A.1
-
13
-
-
0037198427
-
Effects of insulin in relatives of patients with type 1 diabetes mellitus
-
Diabetes Prevention Trial-Type 1 Diabetes Study Group
-
Diabetes Prevention Trial-Type 1 Diabetes Study Group. Effects of insulin in relatives of patients with type 1 diabetes mellitus. N. Engl. J. Med. 346, 1685-1691 (2002).
-
(2002)
N. Engl. J. Med
, vol.346
, pp. 1685-1691
-
-
-
14
-
-
18144391496
-
Effects of oral insulin in relatives of patients with type 1 diabetes mellitus
-
Diabetes Prevention Trial-Type 1 Diabetes Study Group
-
Diabetes Prevention Trial-Type 1 Diabetes Study Group. Effects of oral insulin in relatives of patients with type 1 diabetes mellitus. Diabetes Care 28, 1068-1076 (2005).
-
(2005)
Diabetes Care
, vol.28
, pp. 1068-1076
-
-
-
15
-
-
0030175957
-
Beta-cell autoantibodies in infants and toddlers without IDDM relatives: Diabetes Autoimmunity Study in the Young (DAISY)
-
Rewers, M. et al. Beta-cell autoantibodies in infants and toddlers without IDDM relatives: Diabetes Autoimmunity Study in the Young (DAISY). J. Autoimmun. 9, 405-410 (1996).
-
(1996)
J. Autoimmun
, vol.9
, pp. 405-410
-
-
Rewers, M.1
-
16
-
-
0033060864
-
Early expression and high prevalence of islet autoantibodies for DR3/4 heterozygous and DR4/4 homozygous offspring of parents with Type I diabetes: The German BABYDIAB study
-
Schenker, M. et al. Early expression and high prevalence of islet autoantibodies for DR3/4 heterozygous and DR4/4 homozygous offspring of parents with Type I diabetes: the German BABYDIAB study. Diabetologia 42, 671-677 (1999).
-
(1999)
Diabetologia
, vol.42
, pp. 671-677
-
-
Schenker, M.1
-
17
-
-
33644761987
-
Natural history of type 1 diabetes
-
Achenbach, P., Bonifacio, E., Koczwara, K. & Ziegler, A.G. Natural history of type 1 diabetes. Diabetes 54(Suppl 2): S25-S31 (2005).
-
(2005)
Diabetes
, vol.54
, Issue.SUPPL. 2
-
-
Achenbach, P.1
Bonifacio, E.2
Koczwara, K.3
Ziegler, A.G.4
-
18
-
-
31844443691
-
Natural history of β-cell function in type 1 diabetes
-
Sherry, N.A., Tsai, E.B. & Herold, K.C. Natural history of β-cell function in type 1 diabetes. Diabetes 54(Suppl 2): S32-S39 (2005).
-
(2005)
Diabetes
, vol.54
, Issue.SUPPL. 2
-
-
Sherry, N.A.1
Tsai, E.B.2
Herold, K.C.3
-
19
-
-
0002704712
-
Immune intervention in type 1 diabetes mellitus
-
Skyler, J.S. & Marks, J.B. Immune intervention in type 1 diabetes mellitus. Diabetes Rev. 1, 15-42 (1993).
-
(1993)
Diabetes Rev
, vol.1
, pp. 15-42
-
-
Skyler, J.S.1
Marks, J.B.2
-
20
-
-
0030892035
-
Prevention of type I diabetes and recurrent-cell destruction of transplanted islets
-
Slover, R.H. & Eisenbarth, G.S. Prevention of type I diabetes and recurrent-cell destruction of transplanted islets. Endocr. Rev. 18, 241-258 (1997).
-
(1997)
Endocr. Rev
, vol.18
, pp. 241-258
-
-
Slover, R.H.1
Eisenbarth, G.S.2
-
21
-
-
85011453152
-
Now is the time to prevent type 1 diabetes
-
Schatz, D.A., Krischer, J.P. & Skyler, J.S. Now is the time to prevent type 1 diabetes. J Clin. Endocrinol. Metab. 85, 495-498 (1999).
-
(1999)
J Clin. Endocrinol. Metab
, vol.85
, pp. 495-498
-
-
Schatz, D.A.1
Krischer, J.P.2
Skyler, J.S.3
-
22
-
-
0034781727
-
Does partial preservation of residual beta-cell function justify immune intervention in recent onset Type I diabetes?
-
Kolb, H. & Gale, E.A. Does partial preservation of residual beta-cell function justify immune intervention in recent onset Type I diabetes? Diabetologia 44, 1349-1353 (2001).
-
(2001)
Diabetologia
, vol.44
, pp. 1349-1353
-
-
Kolb, H.1
Gale, E.A.2
-
23
-
-
0022619110
-
-
Feutren, G., et al. & for the Cyclosporin/Diabetes French Study Group. Cyclosporin increases the rate and length of remissions in insulin dependent diabetes of recent onset: results of a multicentre double-blind trial. Lancet ii, 119-124 (1986).
-
Feutren, G., et al. & for the Cyclosporin/Diabetes French Study Group. Cyclosporin increases the rate and length of remissions in insulin dependent diabetes of recent onset: results of a multicentre double-blind trial. Lancet ii, 119-124 (1986).
-
-
-
-
24
-
-
0023709376
-
Cyclosporin-induced remission of IDDM after early intervention: Association of 1 year of cyclosporin treatment with enhanced insulin secretion
-
The Canadian-European Randomized Control Trial Group
-
The Canadian-European Randomized Control Trial Group. Cyclosporin-induced remission of IDDM after early intervention: association of 1 year of cyclosporin treatment with enhanced insulin secretion. Diabetes 37, 1574-1582 (1988).
-
(1988)
Diabetes
, vol.37
, pp. 1574-1582
-
-
-
25
-
-
0026969225
-
-
Skyler, J.S., Rabinovitch, A. & Miami Cyclosporine Diabetes Study Group. Cyclosporine in recent onset type 1 diabetes mellitus: effects on islet beta cell function. J. Diabetes Complicat. 6, 77-88 (1992).
-
Skyler, J.S., Rabinovitch, A. & Miami Cyclosporine Diabetes Study Group. Cyclosporine in recent onset type 1 diabetes mellitus: effects on islet beta cell function. J. Diabetes Complicat. 6, 77-88 (1992).
-
-
-
-
26
-
-
0022353991
-
Increase in remission rate in newly diagnosed type 1 diabetic subjects treated with Azathioprine
-
Harrison, L.C., Colman, P.G., Dean, B., Baxter, R. & Martin, F.I.R. Increase in remission rate in newly diagnosed type 1 diabetic subjects treated with Azathioprine. Diabetes 34, 1306-1308 (1985).
-
(1985)
Diabetes
, vol.34
, pp. 1306-1308
-
-
Harrison, L.C.1
Colman, P.G.2
Dean, B.3
Baxter, R.4
Martin, F.I.R.5
-
27
-
-
0023735943
-
Immunosuppression with Azathioprine and Prednisone in recent onset insulin-dependent diabetes mellitus
-
Silverstein, J., Maclaren, N., Riley, W., Spillar, R., Radjenovic, D. & Johnson, S. Immunosuppression with Azathioprine and Prednisone in recent onset insulin-dependent diabetes mellitus. N. Engl. J. Med. 319, 599-604 (1988).
-
(1988)
N. Engl. J. Med
, vol.319
, pp. 599-604
-
-
Silverstein, J.1
Maclaren, N.2
Riley, W.3
Spillar, R.4
Radjenovic, D.5
Johnson, S.6
-
28
-
-
0024813410
-
A double-blind controled trial of Azathioprine in children with newly-diagnosed type 1 diabetes
-
Cook, J.J. et al. A double-blind controled trial of Azathioprine in children with newly-diagnosed type 1 diabetes. Diabetes 38, 779-783 (1989).
-
(1989)
Diabetes
, vol.38
, pp. 779-783
-
-
Cook, J.J.1
-
29
-
-
0030058792
-
Long-term results of early cyclosporin therapy in juvenile IDDM
-
De Filippo, G., Carel, J.C., Boitard, C. & Bougnères, P.F. Long-term results of early cyclosporin therapy in juvenile IDDM. Diabetes 45, 101-104 (1996).
-
(1996)
Diabetes
, vol.45
, pp. 101-104
-
-
De Filippo, G.1
Carel, J.C.2
Boitard, C.3
Bougnères, P.F.4
-
30
-
-
0033009588
-
Cyclosporine nephrotoxicity in type 1 diabetic patients. A 7-year follow-up study
-
Parving, H.H. et al. Cyclosporine nephrotoxicity in type 1 diabetic patients. A 7-year follow-up study. Diabetes Care 22, 478-483 (1999).
-
(1999)
Diabetes Care
, vol.22
, pp. 478-483
-
-
Parving, H.H.1
-
31
-
-
0022414133
-
Reduction of diabetes incidence of BB Wistar rats by early prophylactic insulin treatment of diabetes-prone animals
-
Gotfredsen, G.F., Buschard, K. & Frandsen, E.K. Reduction of diabetes incidence of BB Wistar rats by early prophylactic insulin treatment of diabetes-prone animals. Diabetologia 28, 933-935 (1985).
-
(1985)
Diabetologia
, vol.28
, pp. 933-935
-
-
Gotfredsen, G.F.1
Buschard, K.2
Frandsen, E.K.3
-
32
-
-
0022653109
-
Insulin injections prevent diabetes (DB) in BioBreeding/Worcester (BB/W) rats
-
Like, A.A. Insulin injections prevent diabetes (DB) in BioBreeding/Worcester (BB/W) rats. Diabetes 136, 3254-3258 (1986).
-
(1986)
Diabetes
, vol.136
, pp. 3254-3258
-
-
Like, A.A.1
-
33
-
-
0025472820
-
Insulitis and insulin dependent diabetes in NOD mice reduced by prophylactic insulin therapy
-
Atkinson, M.A., Maclaren, N.K. & Luchetta, R. Insulitis and insulin dependent diabetes in NOD mice reduced by prophylactic insulin therapy. Diabetes 39, 933-937 (1990).
-
(1990)
Diabetes
, vol.39
, pp. 933-937
-
-
Atkinson, M.A.1
Maclaren, N.K.2
Luchetta, R.3
-
34
-
-
0027480065
-
Insulin prophylaxis in individuals at high risk of type 1 diabetes
-
Keller, R.J., Eisenbarth, G.S. & Jackson, R.A. Insulin prophylaxis in individuals at high risk of type 1 diabetes. Lancet 341, 927-928 (1993).
-
(1993)
Lancet
, vol.341
, pp. 927-928
-
-
Keller, R.J.1
Eisenbarth, G.S.2
Jackson, R.A.3
-
35
-
-
0031976734
-
Delay of type I diabetes in high risk, first degree relatives by parenteral antigen administration: The Schwabing Insulin Prophylaxis Pilot Trial
-
Füchtenbusch, M., Rabl, W., Grassl, B., Bachmann, W., Standl, E. & Ziegler, A.G. Delay of type I diabetes in high risk, first degree relatives by parenteral antigen administration: the Schwabing Insulin Prophylaxis Pilot Trial. Diabetologia 41, 536-541 (1998).
-
(1998)
Diabetologia
, vol.41
, pp. 536-541
-
-
Füchtenbusch, M.1
Rabl, W.2
Grassl, B.3
Bachmann, W.4
Standl, E.5
Ziegler, A.G.6
-
36
-
-
0031055406
-
Oral tolerance for the treatment of autoimmune diseases
-
Weiner, H.L. Oral tolerance for the treatment of autoimmune diseases. Annu. Rev. Med. 48, 341-351 (1997).
-
(1997)
Annu. Rev. Med
, vol.48
, pp. 341-351
-
-
Weiner, H.L.1
-
37
-
-
0025837184
-
Suppression of diabetes in non obese diabetic mice by oral administration of porcine insulin
-
Zhong, Z.J., Davidson, L., Eisenbarth, G.S. & Weiner, H.L. Suppression of diabetes in non obese diabetic mice by oral administration of porcine insulin. Proc. Natl. Acad. Sci. USA 88, 10252-10256 (1991).
-
(1991)
Proc. Natl. Acad. Sci. USA
, vol.88
, pp. 10252-10256
-
-
Zhong, Z.J.1
Davidson, L.2
Eisenbarth, G.S.3
Weiner, H.L.4
-
38
-
-
0028099535
-
Oral administration of human insulin to NOD mice generates CD4+ T cells that suppress adoptive transfer of diabetes
-
Bergerot, I., Fabien, N., Maguer, V & Thivolet, C. Oral administration of human insulin to NOD mice generates CD4+ T cells that suppress adoptive transfer of diabetes. J. Autoimmun. 7, 655-663 (1994).
-
(1994)
J. Autoimmun
, vol.7
, pp. 655-663
-
-
Bergerot, I.1
Fabien, N.2
Maguer, V.3
Thivolet, C.4
-
39
-
-
0029744298
-
Oral insulin treatment suppresses virus-induced antigen-specific destruction of beta cells and prevents autoimmune diabetes in transgenic mice
-
von Herrath, M.G., Dyrberg, T. & Oldstone, M.B. Oral insulin treatment suppresses virus-induced antigen-specific destruction of beta cells and prevents autoimmune diabetes in transgenic mice. J. Clin. Invest. 98, 1324-1331 (1996).
-
(1996)
J. Clin. Invest
, vol.98
, pp. 1324-1331
-
-
von Herrath, M.G.1
Dyrberg, T.2
Oldstone, M.B.3
-
40
-
-
1642277657
-
European Nicotinamide Diabetes Intervention Trial (ENDIT): A randomised controlled trial of intervention before the onset of type 1 diabetes
-
European Nicotinamide Diabetes Intervention Trial ENDIT
-
European Nicotinamide Diabetes Intervention Trial (ENDIT). European Nicotinamide Diabetes Intervention Trial (ENDIT): a randomised controlled trial of intervention before the onset of type 1 diabetes. Lancet 363, 925-931 (2004).
-
(2004)
Lancet
, vol.363
, pp. 925-931
-
-
-
41
-
-
0033816148
-
Effect of cow's milk exposure and maternal type 1 diabetes on cellular and humoral immunization to dietary insulin in infants at genetic risk for type 1 diabetes. Finnish Trial to Reduce IDDM in the Genetically at Risk Study Group
-
Paronen, J. et al. Effect of cow's milk exposure and maternal type 1 diabetes on cellular and humoral immunization to dietary insulin in infants at genetic risk for type 1 diabetes. Finnish Trial to Reduce IDDM in the Genetically at Risk Study Group. Diabetes 49, 1657-1665 (2000).
-
(2000)
Diabetes
, vol.49
, pp. 1657-1665
-
-
Paronen, J.1
-
42
-
-
0035944844
-
Beta-cell function in new-onset type 1 diabetes and immunomodulation with a heat-shock protein peptide (DiaPep277): A randomised, double-blind, phase II trial
-
Raz, I., Elias, D., Avron, A., Tamir, M., Metzger, M. & Cohen, I.R. Beta-cell function in new-onset type 1 diabetes and immunomodulation with a heat-shock protein peptide (DiaPep277): a randomised, double-blind, phase II trial. Lancet 358, 1749-1753 (2001).
-
(2001)
Lancet
, vol.358
, pp. 1749-1753
-
-
Raz, I.1
Elias, D.2
Avron, A.3
Tamir, M.4
Metzger, M.5
Cohen, I.R.6
-
43
-
-
21344461521
-
Clinical evidence for the safety of GAD65 immunomodulation in adult-onset autoimmune diabetes
-
Agardh, C.D. et al. Clinical evidence for the safety of GAD65 immunomodulation in adult-onset autoimmune diabetes. J. Diabetes Complicat. 19, 238-246 (2005).
-
(2005)
J. Diabetes Complicat
, vol.19
, pp. 238-246
-
-
Agardh, C.D.1
-
44
-
-
0037198420
-
Anti-CD3 monoclonal antibody in new-onset type 1 diabetes mellitus
-
Herold, K.C. et al. Anti-CD3 monoclonal antibody in new-onset type 1 diabetes mellitus. N. Engl. J. Med. 346, 1692-1698 (2002).
-
(2002)
N. Engl. J. Med
, vol.346
, pp. 1692-1698
-
-
Herold, K.C.1
-
45
-
-
20544443927
-
Insulin needs after CD3-antibody therapy in new-onset type 1 diabetes
-
Keymeulen, B. et al. Insulin needs after CD3-antibody therapy in new-onset type 1 diabetes. N. Engl. J. Med. 352, 2598-2608 (2005).
-
(2005)
N. Engl. J. Med
, vol.352
, pp. 2598-2608
-
-
Keymeulen, B.1
|