Nonmitogenic anti-CD3 monoclonal antibodies deliver a partial T cell receptor signal and induce clonal anergy

Journal of Experimental Medicine

Volumn 185, Issue 8, 1997, Pages 1413-1422

  Smith, Judith A ^a   Tso, J Yun ^b   Clark, Marcus R ^a   Cole, Michael S ^b   Bluestone, Jeffrey A ^a,c  

^a UNIVERSITY OF CHICAGO   (United States)

^b PROTEIN DESIGN LABS INC   (United States)

^c Cancer Biology and Developmental Biology   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN F(AB')2 FRAGMENT; OKT 3; OKT 4; PHOSPHOLIPASE C; PROTEIN P21; PROTEIN TYROSINE KINASE; T LYMPHOCYTE RECEPTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CALCIUM TRANSPORT; CLONAL ANERGY; CONTROLLED STUDY; GRAFT REJECTION; HYBRIDOMA; IMMUNOSUPPRESSIVE TREATMENT; LYMPHOCYTE CLONE; MITOGENESIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; T LYMPHOCYTE ACTIVATION;

ANIMALS; ANTIBODIES, MONOCLONAL; ANTIGENS, CD3; CLONAL ANERGY; IMMUNOSUPPRESSION; LYMPH NODES; LYMPHOCYTE ACTIVATION; MICE; MICE, INBRED BALB C; MICE, INBRED DBA; PHOSPHORYLATION; PHOSPHOTYROSINE; PROTEIN-TYROSINE KINASES; RECEPTOR AGGREGATION; RECEPTORS, ANTIGEN, T-CELL; SIGNAL TRANSDUCTION; T-LYMPHOCYTES; ZAP-70 PROTEIN-TYROSINE KINASE;

EID: 0030896612     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.185.8.1413     Document Type: Article

References (36)

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