Autoimmunity to both proinsulin and IGRP is required for diabetes in nonobese diabetic 8.3 TCR transgenic mice

Journal of Immunology

Volumn 180, Issue 7, 2008, Pages 4458-4464

  Krishnamurthy, Balasubramanian ^a   Mariana, Lina ^a   Gellert, Shane A ^b   Colman, Peter G ^b   Harrison, Leonard C ^c   Lew, Andrew M ^c   Santamaria, Pere ^d   Thomas, Helen E ^a   Kay, Thomas W H ^a,e  

^a ST VINCENT'S INSTITUTE OF MEDICAL RESEARCH   (Australia)

^b ROYAL MELBOURNE HOSPITAL   (Australia)

^c WALTER AND ELIZA HALL INSTITUTE OF MEDICAL RESEARCH   (Australia)

^d UNIVERSITY OF CALGARY   (Canada)

^e UNIVERSITY OF MELBOURNE   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIBODY; GLUCOSE 6 PHOSPHATASE; ISLET SPECIFIC GLUCOSE 6 PHOSPHATASE CATALYTIC SUBUNIT RELATED PROTEIN; PROINSULIN; PROINSULIN 2; STREPTOZOCIN; UNCLASSIFIED DRUG; LYMPHOCYTE ANTIGEN RECEPTOR; PEPTIDE FRAGMENT;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIGEN PRESENTING CELL; ARTICLE; AUTOIMMUNITY; CD8+ T LYMPHOCYTE; CELL PROLIFERATION; CELL SPECIFICITY; CONTROLLED STUDY; DIABETES MELLITUS; MOUSE; NONHUMAN; NONOBESE DIABETIC MOUSE; PANCREAS ISLET CELL; PANCREATITIS; PRIORITY JOURNAL; STREPTOZOCIN DIABETES; T LYMPHOCYTE; TRANSGENIC MOUSE; ANIMAL; ANTIGEN PRESENTATION; CELL CULTURE; DRUG EFFECT; ENZYMOLOGY; GENETICS; IMMUNOLOGICAL TOLERANCE; IMMUNOLOGY; METABOLISM; PANCREAS ISLET;

ANIMALS; ANTIGEN PRESENTATION; AUTOIMMUNITY; CELLS, CULTURED; DIABETES MELLITUS; GLUCOSE-6-PHOSPHATASE; IMMUNE TOLERANCE; ISLETS OF LANGERHANS; MICE; MICE, INBRED NOD; MICE, TRANSGENIC; PEPTIDE FRAGMENTS; PROINSULIN; RECEPTORS, ANTIGEN, T-CELL;

EID: 44449148889     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.180.7.4458     Document Type: Article

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