Conformational constraining of inactive and active states of a seven transmembrane receptor by metal ion site engineering in the extracellular end of transmembrane segment V

Molecular Pharmacology

Volumn 70, Issue 6, 2006, Pages 1892-1901

  Rosenkilde, Mette M ^a   David, Ralf ^b   Oerlecke, Ilka ^a   Benned Jensen, Tau ^a   Geumann, Ulf ^b   Beck Sickinger, Anette G ^b   Schwartz, Thue W ^a  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

^b UNIVERSITY OF LEIPZIG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA CHEMOKINE; CHEMOKINE; CHEMOKINE RECEPTOR CXCR1; MELANOMA GROWTH STIMULATORY ACTIVITY FACTOR; MEMBRANE PROTEIN; MEMBRANE RECEPTOR; METAL ION;

ANIMAL CELL; ARTICLE; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; HUMAN HERPESVIRUS 8; MEMBRANE POTENTIAL; METAL BINDING; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

AMINO ACID SEQUENCE; BASE SEQUENCE; BINDING, COMPETITIVE; CIRCULAR DICHROISM; CLONING, MOLECULAR; DNA PRIMERS; ENZYME-LINKED IMMUNOSORBENT ASSAY; ESCHERICHIA COLI; HUMANS; MOLECULAR SEQUENCE DATA; PROTEIN CONFORMATION; PROTEIN ENGINEERING; RECEPTORS, CELL SURFACE;

EID: 33751111710     PISSN: 0026895X     EISSN: 15210111     Source Type: Journal    
DOI: 10.1124/mol.106.027425     Document Type: Article

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