RNA interference-mediated c-MYC inhibition prevents cell growth and decreases sensitivity to radio- and chemotherapy in childhood medulloblastoma cells

BMC Cancer

Volumn 9, Issue , 2009, Pages

  von Bueren, André O ^a   Shalaby, Tarek ^a   Oehler Jänne, Christoph ^b   Arnold, Lucia ^a   Stearns, Duncan ^c   Eberhart, Charles G ^c   Arcaro, Alexandre ^a   Pruschy, Martin ^b   Grotzer, Michael A ^a  

^a UNIVERSITY CHILDREN S HOSPITAL   (Switzerland)

^b UNIVERSITY HOSPITAL ZURICH   (Switzerland)

^c JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; CISPLATIN; ETOPOSIDE; MYC PROTEIN; SMALL INTERFERING RNA; TELOMERASE; TELOMERASE REVERSE TRANSCRIPTASE;

APOPTOSIS; ARTICLE; CANCER CELL; CANCER CELL CULTURE; CANCER CHEMOTHERAPY; CANCER RADIOTHERAPY; CELL CYCLE; CELL CYCLE G1 PHASE; CELL CYCLE PROGRESSION; CELL CYCLE S PHASE; CELL GROWTH; CELL PROLIFERATION; CHILD; CHILDHOOD CANCER; CONTROLLED STUDY; DOWN REGULATION; DRUG SENSITIVITY; ENZYME ACTIVITY; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; IONIZING RADIATION; MEDULLOBLASTOMA; PRESCHOOL CHILD; PROTEIN EXPRESSION; PROTEIN FUNCTION; RNA INTERFERENCE; TELOMERE; WESTERN BLOTTING; DRUG EFFECT; DRUG THERAPY; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; MULTIMODALITY CANCER THERAPY; PATHOPHYSIOLOGY; RADIATION EXPOSURE; RADIOTHERAPY; TUMOR CELL LINE;

APOPTOSIS; CELL CYCLE; CELL LINE, TUMOR; CELL PROLIFERATION; COMBINED MODALITY THERAPY; DOWN-REGULATION; DRUG THERAPY; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; MEDULLOBLASTOMA; PROTO-ONCOGENE PROTEINS C-MYC; RADIATION, IONIZING; RADIOTHERAPY; RNA INTERFERENCE; TELOMERASE;

EID: 61849158867     PISSN: None     EISSN: 14712407     Source Type: Journal    
DOI: 10.1186/1471-2407-9-10     Document Type: Article

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