C-MYC expression in medulloblastoma and its prognostic value

International Journal of Cancer

Volumn 89, Issue 5, 2000, Pages 395-402

  Herms, Jochen ^a,j   Neidt, Iris ^g   Lüscher, Bernhard ^h   Sommer, Annete ⁱ   Schürmann, Peter ^a   Schröder, Thomas ^c   Bergmann, Markus ^d   Wilken, Bernd ^a   Probst Cousin, Stephan ^e   Hernáiz Driever, Pablo ^f   Behnke, Julianne ^b   Hanefeld, Folker ^a   Pietsch, Torsten ^g   Kretzschmar, Hans A ^j  

^a UNIVERSITY OF GÖTTINGEN   (Germany)

^b ZENTRALKLINIK BAD BERKA   (Germany)

^c Herzzentrum Lahr ^*  (Germany)

^d Institut für Klinische Neuropathologie   (Germany)

^e UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

^f CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^g UNIVERSITY OF BONN   (Germany)

^h HANNOVER MEDICAL SCHOOL   (Germany)

ⁱ BAYER PHARMA AG   (Germany)

^j UNIVERSITY OF MUNICH   (Germany)

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Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; SYNAPTOPHYSIN;

ADOLESCENT; ADULT; ARTICLE; BRAIN TUMOR; CANCER MORTALITY; CANCER SURVIVAL; CHILD; FEMALE; GENE AMPLIFICATION; GENE EXPRESSION; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; INFANT; MAJOR CLINICAL STUDY; MALE; MEDULLOBLASTOMA; METASTASIS; MULTIMODALITY CANCER THERAPY; ONCOGENE C MYC; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROGNOSIS; PROTEIN EXPRESSION;

ADOLESCENT; ADULT; CEREBELLAR NEOPLASMS; CHILD; CHILD, PRESCHOOL; FEMALE; GENE DOSAGE; GENES, MYC; HUMAN; INFANT; MALE; MEDULLOBLASTOMA; MIDDLE AGE; PROGNOSIS; SUPPORT, NON-U.S. GOV'T; SURVIVAL RATE;

EID: 0033801873     PISSN: 00207136     EISSN: None     Source Type: Journal    
DOI: 10.1002/1097-0215(20000920)89:5<395::AID-IJC1>3.0.CO;2-V     Document Type: Article

References (37)

1. Chromosomal abnormalities in 47 pediatric brain tumors
2. Effects of medulloblastoma resections on outcome in children: A report from the Children's Cancer Group
3. N-myc and c-myc oncogene amplification in medulloblastomas. Evidence of particularly aggressive behavior of a tumor with c-myc amplification
4. Prospective randomised trial of chemotherapy given before radiotherapy in childhood medulloblastoma. International Society of Paediatric Oncology (SLOP) and the (German) Society of Paediatric Oncology (GPO): SlOP II
5. Prognostic implications of chromosome 17p deletions in human medulloblastomas
6. Oncogenes and anti-oncogenes in human central nervous system tumors
7. Evidence for a 17p tumor related locus distinct from p53 in pediatric primitive neuroectodermal tumors
8. Isochromosome 17q in primitive neuroectodermal tumors of the central nervous system
9. Structural chromosomal abnormalities in human medulloblastoma
10. Expression of the c-Myc protein in childhood medulloblastoma
11. An operative staging system and a megavoltage radiotherapeutic technique for cerebellar medulloblastomas
12. c-Myc target genes involved in cell growth, apoptosis, and metabolism
13. The treatment of medulloblastoma. Results of a prospective randomized trial of radiation therapy with and without CCNU, vincristine, and prednisone
14. Animal models of medulloblastomas and related primitive neuroectodermal tumors. A review
15. Proteins of the myc network: Essential regulator of cell growth and differentiation
16. 2+/calmodulin protein kinase and protein kinase C expression during development of rat hippocampus
17. Expression of the myc proto-oncogenes in developing human fetal brain
18. Nonparametric estimation from incomplete observations
19. The new WHO classification of brain tumours
20. Preradiation chemotherapy of children and young adults with malignant brain tumors: Results of the German pilot trial HIT'88/'89
21. The basic region/helix-loop-helix/leucine zipper domain of Myc proto-oncoproteins: Function and regulation
22. Elevated c-myc expression in childhood medulloblastomas
23. Myc function and regulation
24. Prospective randomized cooperative medulloblastoma trial (MED 84) of the International Society of Paediatric Oncology (SLOP) and of the (German) Society of Paediatric Oncology (GPO)
25. Cytogenetic analysis of 109 pediatric central nervous system tumors
26. Expression of c-myc and c-fos oncogenes in different rat regions during postnatal development
27. Characterization of five new cell lines derived from human primitive neuroectodermal tumors of the central nervous system
28. Reduction to homozygosity and gene amplification in central nervous system primitive neuroectodermal tumors of childhood
29. Proto-oncogene c-myc is expressed in cerebellar neurons at different developmental stages
30. Molecular cytogenetic analysis of a medulloblastoma with isochromosome 17 and double minutes
31. Molecular analysis of childhood primitive neuroectodermal tumors defines markers associated with poor outcome
32. Alterations and abnormal expression of the c-myc oncogene in human multiple myeloma
33. A rapid and sensitive protocol for competitive reverse transcriptase (cRT) PCR analysis of cellular genes
34. Oncogene amplification in pediatric brain tumors
35. An optimized protocol for mRNA quantification using nested competitive RT-PCR
36. Cerebellar dysplasias in humans: Development and possible relationship to glial and primitive neuroectodermal tumors of the cerebellar vermis