Expression profile of the putative catalytic subunit of the telomerase gene

Cancer Research

Volumn 58, Issue 4, 1998, Pages 622-625

  Ramakrishnan, Shyam ^a   Eppenberger, Urs ^b   Mueller, Heinz ^b   Shinkai, Youichi ^c   Narayanan, Ramaswamy ^a,d  

^a HOFFMANN LA ROCHE INC   (United States)

^b UNIVERSITY HOSPITAL BASEL   (Switzerland)

^c NIPPON ROCHE RESEARCH CENTER   (Japan)

^d FLORIDA ATLANTIC UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

TELOMERASE;

ANIMAL CELL; ARTICLE; DOWN REGULATION; ENZYME ACTIVE SITE; ENZYME SUBUNIT; FIBROBLAST; GENE EXPRESSION REGULATION; HUMAN; MOLECULAR CLONING; NONHUMAN; PRIORITY JOURNAL; SEQUENCE HOMOLOGY; TETRAHYMENA; TISSUE DIFFERENTIATION;

BREAST NEOPLASMS; CELL DIFFERENTIATION; CELLS, CULTURED; DOWN-REGULATION; GENE EXPRESSION; HL-60 CELLS; HUMANS; NEOPLASMS; POLYMERASE CHAIN REACTION; TELOMERASE; TISSUE DISTRIBUTION; TRETINOIN; TUMOR CELLS, CULTURED;

EID: 0032519559     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (25)

1. Harley, C. B. Telomere loss: mitotic clock or genetic time bomb? Mutat. Res., 256: 271-282, 1991.
2. de Lange, T. Activation of telomerase in a human tumor. Proc. Natl. Acad. Sci. USA, 91: 2882-2885, 1994.
3. Narayanan, R. Telomerase in cancer: therapeutic and diagnostic potential. In: J. R. Prous (ed.), Drug News and Perspectives, pp. 69-73. Barcelona, Spain: Prous Science Publishers, 1997.
4. Kim, N. W., Piatyszek, M. A., Prowse, K. R., Harley, C. B., West, M. D., Ho, P. L., Coviello, G. M., Wright, W. E., Weinrich, S. L., and Shay, J. W. Specific association of human telomerase activity with immortal cells and cancer. Science (Washington DC), 266: 2011-2015, 1994.
5. Broccoli, D., Young, J. W., and de Lange, T. Telomerase activity in normal and malignant hematopoietic cells. Proc. Natl. Acad. Sci. USA, 92: 9082-9086, 1995.
6. Counter, C. M., Gupta, J., Harley, C. B., Leber, B., and Bacchetti, S. Telomerase activity in normal leukocytes and in hematologic malignancies. Blood, 85: 2315-2320, 1995.
7. Hsiao, R., Higgins-Sochaski, K. A., Domingos, J., Keith, E., and Narayanan, R. Telomerase activity in endothelial cells. Anticancer Res., 17: 827-832, 1997.
8. Harle-Bachor, C., and Boukamp, P. Telomerase activity in the regenerative basal layer of the epidermis in human skin and in immortal and carcinoma-derived skin keratinocytes. Proc. Natl. Acad. Sci. USA, 93: 6476-6481, 1996.
9. Norrback, K. F., Dahlenborg, K., Carlsson, R., and Roos, G. Telomerase activation in normal B lymphocytes and non-Hodgkin's lymphomas. Blood, 88: 222-229, 1996.
10. Wright, W. E., Piatyszek, M. A., Rainey, W. E., Byrd, W., and Shay, J. W. Telomerase activity in human germline and embryonic tissues and cells. Dev. Genet., 18: 173-179, 1996.
11. Feng, J., Funk, W. D., Wang, S. S., Weinrich, S. L., Avilion, A. A., Chiu, C. P., Adams, R. R., Chang, E., Allsopp, R. C., Yu, J., Le, S., West, M. D., Harley, C. B., Andrews, W. H., Greider, G. W., and Villeponteau, B. The RNA component of human telomerase. Science (Washington DC), 269: 1236-1241, 1995.
12. Blasco, M. A., Funk, W., Villeponteau, B., and Greider, C. W. Functional characterization and developmental regulation of mouse telomerase RNA. Science (Washington DC), 269: 1267-1270, 1995.
13. Avilion, A. A., Piatyszek, M. A., Gupta, J., Shay, J. W., Bacchetti, S., and Greider, C. W. Human telomerase RNA and telomerase activity in immortal cell lines and tumor tissues. Cancer Res., 56: 645-650, 1996.
14. Harrington, L., McPhail, T., Mar, V., Zhou, W., Oulton, R., Bass, M. B., Arruda, I., and Robinson, M. O. A mammalian telomerase-associated protein. Science (Washington DC), 275: 973-977, 1997.
15. Nakayama, J., Saito, M., Nakamura, H., Matsuura, A., and Ishikawa, F. TLP1: a gene encoding a protein component of mammalian telomerase is a novel member of WD repeats family. Cell, 88: 875-884, 1997.
16. Counter, C. M., Meyerson, M., Eaton, E. N., and Weinberg, R. A. The catalytic subunit of yeast telomerase. Proc. Natl. Acad. Sci. USA, 94: 9202-9207, 1997.
17. Meyerson, M., Counter, C. M., Eaton, E. N., Ellisen, L. W., Steiner, P., Caddie, S. D., Ziaugra, L., Beijersbergen, R. L., Davidoff, M. J., Liu, Q., Bacchetti, S., Haber, D. A., and Weinberg, R. A. hEST2, the putative human telomerase catalytic subunit gene, is up-regulated in tumor cells and during immortalization. Cell, 90: 785-795, 1997.
18. Nakamura, T. M., Morin, G. B., Chapman, K. B., Weinrich, S. L., Andrews, W. H., Lingner, J., Harley, C. B., and Cech, T. R. Telomerase catalytic subunit homologs from fission yeast and human. Science (Washington DC), 277: 955-959, 1997.
19. Counter, C. M., Hirte, H. W., Bacchetti, S., and Harley, C. B. Telomerase activity in human ovarian carcinoma. Proc. Natl. Acad. Sci. USA, 91: 2900-2904, 1994.
20. Sharma, H. W., Sokoloski, J. A., Perez, J. R., Maltese, J. Y., Sartorelli, A. C., Stein, C. A., Nichols, C. G., Khaled, Z., Telang, N. T., and Narayanan, R. Differentiation of immortal cells inhibits telomerase activity. Proc. Natl. Acad. Sci. USA, 92: 12343-12346, 1995.
21. Holt, S. E., Wright, W. E., and Shay, J. W. Regulation of telomerase activity in immortal cell lines. Mol. Cell. Biol., 16: 2932-2939, 1996.
22. Ramakrishnan, S., Sharma, H. W., Farris, A. D., Kaufman, K. M., Harley, J. B., Collins, K., Pruijn, G. J., Van Venrooij, W. J., Martin, M. L., and Narayanan, R. Characterization of human telomerase complex. Proc. Natl. Acad. Sci. USA, 94: 10075-10079, 1997.
23. Lingner, J., Hughes, T. R., Shevchenko, A., Mann, M., Lundblad, V., and Cech, T. R. Reverse transcriptase motifs in the catalytic subunit of telomerase. Science (Washington DC), 276: 561-567, 1997.
24. Murray, G. I., Taylor, M. C., McFadyen, M. C., McKay, J. A., Greenlee, W. F., Burke, M. D., and Melvin, W. T. Tumor-specific expression of cytochrome P450 CYP1B1. Cancer Res., 57: 3026-3031, 1997.
25. Killian, A., Bowtell, D. L., Abud, H. E., Hime, G. R., Venter, D. J., Keese, P. K., Duncan, E. L., Reddel, R. R., and Jefferson, R. A. Isolation of a candidate human telomerase catalytic subunit gene, which reveals complex splicing patterns in different cell types. Hum. Mol. Genet., 6: 2011-2019, 1997.