p27Kip1 is inactivated in human colorectal cancer by cytoplasmic localization associated with activation of Akt/PKB

International Journal of Oncology

Volumn 34, Issue 1, 2009, Pages 69-77

  Bottini, C ^a   Platini, F ^a   Rinaldi, M ^a   Leutner, M ^b   Alabiso, O ^a,b   Garavoglia, M ^a,b   Tessitore, Luciana ^a  

^a UNIVERSITY OF EASTERN PIEDMONT   (Italy)

^b Azienda Ospedaliero Universitaria Maggiore della Carità ^*  (Italy)

Author keywords

Akt PKB; Colorectal cancer; Cytoplasmic p27Kip1; p27Kip1

Indexed keywords

CYCLIN DEPENDENT KINASE INHIBITOR 1B; PROTEIN KINASE B; TUMOR MARKER;

ADULT; AGED; ARTICLE; CANCER RELAPSE; CANCER SURVIVAL; CARCINOGENESIS; COLORECTAL CANCER; CONTROLLED STUDY; CYTOPLASM; DISTANT METASTASIS; ENZYME ACTIVATION; ENZYME INACTIVATION; FEMALE; HISTOPATHOLOGY; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; INTRACELLULAR SPACE; MAJOR CLINICAL STUDY; MALE; OUTCOME ASSESSMENT; PRIORITY JOURNAL; PROGNOSIS; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; WESTERN BLOTTING; CANCER STAGING; CELL NUCLEUS; COLORECTAL TUMOR; COMPARATIVE STUDY; ENZYME IMMUNOASSAY; GENE EXPRESSION REGULATION; METABOLISM; METASTASIS; MIDDLE AGED; PATHOLOGY; PHOSPHORYLATION; SURVIVAL RATE;

ADULT; AGED; AGED, 80 AND OVER; BLOTTING, WESTERN; CELL NUCLEUS; COLORECTAL NEOPLASMS; CYCLIN-DEPENDENT KINASE INHIBITOR P27; CYTOPLASM; ENZYME ACTIVATION; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; IMMUNOENZYME TECHNIQUES; MALE; MIDDLE AGED; NEOPLASM STAGING; PHOSPHORYLATION; PROGNOSIS; PROTO-ONCOGENE PROTEINS C-AKT; SURVIVAL RATE; TUMOR MARKERS, BIOLOGICAL;

EID: 60749084818     PISSN: 10196439     EISSN: 17912423     Source Type: Journal    
DOI: 10.3892/ijo_00000130     Document Type: Article

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