메뉴 건너뛰기




Volumn 93, Issue 3, 2006, Pages 241-252

p27 downregulation and metallothionein overexpression in gastric cancer patients are associated with a poor survival rate

Author keywords

Cyclins; Gastric cancer; Metallothionein; Molecular markers; p27

Indexed keywords

CYCLIN B1; CYCLIN D3; METALLOTHIONEIN; MOLECULAR MARKER; PROTEIN P27;

EID: 33644904976     PISSN: 00224790     EISSN: 10969098     Source Type: Journal    
DOI: 10.1002/jso.20402     Document Type: Article
Times cited : (40)

References (43)
  • 2
    • 0038826040 scopus 로고    scopus 로고
    • Randomized trial of adjuvant chemotherapy with mitomycin, fluorouracil, and cytosine arabinoside followed by oral fluorouracil in serosa-negative gastric cancer: Japan clinical oncology group 9206-1
    • Nashimoto A. Nakajima T, Furukawa H, et al.: Randomized trial of adjuvant chemotherapy with mitomycin, fluorouracil, and cytosine arabinoside followed by oral fluorouracil in serosa-negative gastric cancer: Japan clinical oncology group 9206-1. J Clin Oncol 2003;12:2282-2287.
    • (2003) J Clin Oncol , vol.12 , pp. 2282-2287
    • Nashimoto, A.1    Nakajima, T.2    Furukawa, H.3
  • 3
    • 1542374692 scopus 로고    scopus 로고
    • Randomized trial of adjuvant chemotherapy after curative resection for gastric cancer
    • Chipponi J, Huguier M, Pezet D, et al.: Randomized trial of adjuvant chemotherapy after curative resection for gastric cancer. Am J Surg 2004;187:440-445.
    • (2004) Am J Surg , vol.187 , pp. 440-445
    • Chipponi, J.1    Huguier, M.2    Pezet, D.3
  • 4
    • 2942638082 scopus 로고    scopus 로고
    • Extended lymph node dissection for gastric cancer: Who may benefit? Final results of the randomized Dutch gastric cancer group trial
    • Hartgrink HH, van de Velde H, Putter H, et al.: Extended lymph node dissection for gastric cancer: Who may benefit? Final results of the randomized Dutch gastric cancer group trial. J Clin Oncol 2004;22:2069-2077.
    • (2004) J Clin Oncol , vol.22 , pp. 2069-2077
    • Hartgrink, H.H.1    Van De Velde, H.2    Putter, H.3
  • 5
    • 0348041949 scopus 로고    scopus 로고
    • Prognostic significance of metastatic lymph node size in patients with gastric cancer
    • Dhar DK, Kubota H, Kinukawa N, et al.: Prognostic significance of metastatic lymph node size in patients with gastric cancer. Br J Surg 2003;90:1522-1530.
    • (2003) Br J Surg , vol.90 , pp. 1522-1530
    • Dhar, D.K.1    Kubota, H.2    Kinukawa, N.3
  • 6
    • 0036833316 scopus 로고    scopus 로고
    • Appraisal of compliance with the UICC/AJCC staging system in the staging of gastric cancer
    • Union Internacional Contra 1a Cancrum/American Joint Committee on Cancer
    • Mullaney PJ, Wadley MS, Hyde C, et al.: Appraisal of compliance with the UICC/AJCC staging system in the staging of gastric cancer. Union Internacional Contra 1a Cancrum/American Joint Committee on Cancer. Br J Surg 2002;89:1405-1408.
    • (2002) Br J Surg , vol.89 , pp. 1405-1408
    • Mullaney, P.J.1    Wadley, M.S.2    Hyde, C.3
  • 7
    • 0038298071 scopus 로고    scopus 로고
    • Future strategies and adjuvant treatment of gastric cancer
    • Falcone A: Future strategies and adjuvant treatment of gastric cancer. Ann Oncol 2003;14:45-47.
    • (2003) Ann Oncol , vol.14 , pp. 45-47
    • Falcone, A.1
  • 8
    • 1542722997 scopus 로고    scopus 로고
    • Molecular markers in gastrointestinal cancer: Targeted therapy and tailored chemotherapy
    • Lenz HJ: Molecular markers in gastrointestinal cancer: Targeted therapy and tailored chemotherapy. Onkologie 2004;27:12-14.
    • (2004) Onkologie , vol.27 , pp. 12-14
    • Lenz, H.J.1
  • 9
    • 1542722999 scopus 로고    scopus 로고
    • Recent results in understanding molecular pathways in the medical treatment of esophageal and gastric cancer
    • Sutter AP, Zeitz M, Scherübl H: Recent results in understanding molecular pathways in the medical treatment of esophageal and gastric cancer. Onkologie 2004;27:17-21.
    • (2004) Onkologie , vol.27 , pp. 17-21
    • Sutter, A.P.1    Zeitz, M.2    Scherübl, H.3
  • 10
    • 3242801340 scopus 로고    scopus 로고
    • Chromosomal and microsatellite instability in sporadic gastric cancer
    • Hiyama T, Tanaka S, Yoshihara M, et al.: Chromosomal and microsatellite instability in sporadic gastric cancer. J Gastroenterol Hepatol 2004;19:756-760.
    • (2004) J Gastroenterol Hepatol , vol.19 , pp. 756-760
    • Hiyama, T.1    Tanaka, S.2    Yoshihara, M.3
  • 11
    • 3042570272 scopus 로고    scopus 로고
    • Association between expression of transcription factor Sp1 and increased vascular endothelial growth factor expression, advanced stage, and poor survival in patients with resected gastric cancer
    • Yao JC, Wang L, Wei D, et al.: Association between expression of transcription factor Sp1 and increased vascular endothelial growth factor expression, advanced stage, and poor survival in patients with resected gastric cancer. Clin Cancer Res 2004;10:4109-4117.
    • (2004) Clin Cancer Res , vol.10 , pp. 4109-4117
    • Yao, J.C.1    Wang, L.2    Wei, D.3
  • 12
    • 0042783125 scopus 로고    scopus 로고
    • Molecular mechanisms of carcinogenesis in gastric cancer
    • Hofler H, Becker KF: Molecular mechanisms of carcinogenesis in gastric cancer. Recent Results Cancer Res 2003;162:65-72.
    • (2003) Recent Results Cancer Res , vol.162 , pp. 65-72
    • Hofler, H.1    Becker, K.F.2
  • 13
    • 0042831247 scopus 로고    scopus 로고
    • Mutations in the yeast cyclin-dependent kinase Cdc28 reveal a role in the spindle assembly checkpoint
    • Kitazono AA, Garza DA, Kron SJ: Mutations in the yeast cyclin-dependent kinase Cdc28 reveal a role in the spindle assembly checkpoint. Mol Genet Genomics 2003;269:672-684.
    • (2003) Mol Genet Genomics , vol.269 , pp. 672-684
    • Kitazono, A.A.1    Garza, D.A.2    Kron, S.J.3
  • 14
    • 0036016536 scopus 로고    scopus 로고
    • 1 phase cyclins in human gastric cancer and gastric mucosa of first-degree relatives
    • 1 phase cyclins in human gastric cancer and gastric mucosa of first-degree relatives. Dig Dis Sci 2002;47:1248-1256.
    • (2002) Dig Dis Sci , vol.47 , pp. 1248-1256
    • Miehlke, S.1    Yu, J.2    Ebert, M.3
  • 15
    • 9144236811 scopus 로고    scopus 로고
    • Nonsteroidal antiinflammatory drug use associated with reduced incidence of adenocarcinomas of the esophagus and gastric cardia that overexpress cyclin D1: A population-based study
    • Gammon MD, Terry MB, Arber N, et al.: Nonsteroidal antiinflammatory drug use associated with reduced incidence of adenocarcinomas of the esophagus and gastric cardia that overexpress cyclin D1: A population-based study. Cancer Epidemiol Biomarkers Prev 2004;13:34-39.
    • (2004) Cancer Epidemiol Biomarkers Prev , vol.13 , pp. 34-39
    • Gammon, M.D.1    Terry, M.B.2    Arber, N.3
  • 17
    • 0036037705 scopus 로고    scopus 로고
    • Overexpression of cyclin Bl in gastric cancer and its clinicopathological significance: An immunohistological study
    • Yasuda M, Takesue F, Inutsuka S, et al.: Overexpression of cyclin Bl in gastric cancer and its clinicopathological significance: An immunohistological study. J Cancer Res Clin Oncol 2002;128:412-416.
    • (2002) J Cancer Res Clin Oncol , vol.128 , pp. 412-416
    • Yasuda, M.1    Takesue, F.2    Inutsuka, S.3
  • 18
    • 0348075994 scopus 로고    scopus 로고
    • Flavopiridol enhances the effect of docetaxel in vitro and in vivo in human gastric cancer cells
    • Motwani M, Rizzo C, Sirotnak F, et al.: Flavopiridol enhances the effect of docetaxel in vitro and in vivo in human gastric cancer cells. Mol Cancer Ther 2003;2:549-555.
    • (2003) Mol Cancer Ther , vol.2 , pp. 549-555
    • Motwani, M.1    Rizzo, C.2    Sirotnak, F.3
  • 19
    • 0029849620 scopus 로고    scopus 로고
    • Cancer cell cycles
    • Sherr CJ: Cancer cell cycles. Science 1996;274:1672-1677.
    • (1996) Science , vol.274 , pp. 1672-1677
    • Sherr, C.J.1
  • 20
    • 0030947356 scopus 로고    scopus 로고
    • kip1 and degree of malignancy in human breast and colorectal cancers
    • kip1 and degree of malignancy in human breast and colorectal cancers. Proc Natl Acad Sci 1997;94:6380-6385.
    • (1997) Proc Natl Acad Sci , vol.94 , pp. 6380-6385
    • Fredersdorf, S.1    Burns, J.2    Milne, A.M.3
  • 21
    • 0031689717 scopus 로고    scopus 로고
    • Down-regulation of p27 is associated with development of colorectal adenocarcinoma metastases
    • Thomas GV, Szigeti K, Murphy M, et al.: Down-regulation of p27 is associated with development of colorectal adenocarcinoma metastases. Am J Pathol 1998;153:681-687.
    • (1998) Am J Pathol , vol.153 , pp. 681-687
    • Thomas, G.V.1    Szigeti, K.2    Murphy, M.3
  • 22
    • 0033626566 scopus 로고    scopus 로고
    • Kip1 protein and ki-67 growth fraction in non-small cell lung cancers
    • Kip1 protein and ki-67 growth fraction in non-small cell lung cancers. Clin Cancer Res 2000;6:4073-4081.
    • (2000) Clin Cancer Res , vol.6 , pp. 4073-4081
    • Hommura, F.1    Dosaka-Akita, H.2    Mishina, T.3
  • 23
    • 0037388601 scopus 로고    scopus 로고
    • Combined loss of PTEN and p27 expression is associated with tumor cell proliferation by Ki-67 and increased risk of recurrent disease in localized prostate cancer
    • Halvorsen OJ, Haukaas SA, Akslen LA: Combined loss of PTEN and p27 expression is associated with tumor cell proliferation by Ki-67 and increased risk of recurrent disease in localized prostate cancer. Clin Cancer Res 2003;9:1474-1479.
    • (2003) Clin Cancer Res , vol.9 , pp. 1474-1479
    • Halvorsen, O.J.1    Haukaas, S.A.2    Akslen, L.A.3
  • 24
    • 2542454710 scopus 로고    scopus 로고
    • Determination of molecular marker expression can predict clinical outcome in colon carcinomas
    • Galizia G, Lieto E, Ferraraccio F, et al.: Determination of molecular marker expression can predict clinical outcome in colon carcinomas. Clin Cancer Res 2004;10:3490-3499.
    • (2004) Clin Cancer Res , vol.10 , pp. 3490-3499
    • Galizia, G.1    Lieto, E.2    Ferraraccio, F.3
  • 25
    • 0034668111 scopus 로고    scopus 로고
    • P27(Kip1) loss does not predict survival in patients with advanced gastric carcinoma
    • Feakins RM, Mulcahy HE, Quaglia A, et al.: p27(Kip1) loss does not predict survival in patients with advanced gastric carcinoma. Cancer 2000;89:1684-1691.
    • (2000) Cancer , vol.89 , pp. 1684-1691
    • Feakins, R.M.1    Mulcahy, H.E.2    Quaglia, A.3
  • 26
    • 0033758099 scopus 로고    scopus 로고
    • Expression of cell-cycle regulators p27 and cyclin e correlates with survival in gastric carcinoma patients
    • So JB, Samarasinge K, Raju GC, et al.: Expression of cell-cycle regulators p27 and cyclin E correlates with survival in gastric carcinoma patients. J Surg Res 2000;94:56-60.
    • (2000) J Surg Res , vol.94 , pp. 56-60
    • So, J.B.1    Samarasinge, K.2    Raju, G.C.3
  • 28
    • 0035663843 scopus 로고    scopus 로고
    • Combined examination of p27(Kip1), p21(Waf1/Cip1), and p53 expression allows precise estimation of prognosis in patients with gastric carcinoma
    • Liu XP, Kawauchi S, Oga A, et al.: Combined examination of p27(Kip1), p21(Waf1/Cip1), and p53 expression allows precise estimation of prognosis in patients with gastric carcinoma. Histopathology 2001;39:603-610.
    • (2001) Histopathology , vol.39 , pp. 603-610
    • Liu, X.P.1    Kawauchi, S.2    Oga, A.3
  • 29
    • 0036381456 scopus 로고    scopus 로고
    • The prognostic value of p27 in gastric cancer
    • Wiksten JP, Lundin J, Nordling S, et al.: The prognostic value of p27 in gastric cancer. Oncology 2002;63:180-184.
    • (2002) Oncology , vol.63 , pp. 180-184
    • Wiksten, J.P.1    Lundin, J.2    Nordling, S.3
  • 30
    • 0036893404 scopus 로고    scopus 로고
    • Low level of p27(Kip1) protein expression in gastric adenocarcinoma is associated with disease progression and poor outcome
    • Nitti D, Belluco C, Mammano E, et al.: Low level of p27(Kip1) protein expression in gastric adenocarcinoma is associated with disease progression and poor outcome. J Surg Oncol 2002;81:167-175.
    • (2002) J Surg Oncol , vol.81 , pp. 167-175
    • Nitti, D.1    Belluco, C.2    Mammano, E.3
  • 31
    • 0037599433 scopus 로고    scopus 로고
    • p27 protein and cancers of the gastrointestinal tract and liver: An overview
    • Chetty R: p27 protein and cancers of the gastrointestinal tract and liver: An overview. J Clin Gastroenterol 2003;37:23-27.
    • (2003) J Clin Gastroenterol , vol.37 , pp. 23-27
    • Chetty, R.1
  • 32
    • 0036284478 scopus 로고    scopus 로고
    • Prognostic significance of metallothionein in human gastrointestinal cancer
    • Janssen MA, van Duijn W, Kubben FJ, et al.: Prognostic significance of metallothionein in human gastrointestinal cancer. Clin Cancer Res 2002;8:1889-1896.
    • (2002) Clin Cancer Res , vol.8 , pp. 1889-1896
    • Janssen, M.A.1    Van Duijn, W.2    Kubben, F.J.3
  • 33
    • 0033819678 scopus 로고    scopus 로고
    • Immunohistochemical detection of metallothionein in carcinomatous and normal human gastric mucosa
    • Tuccari G, Giuffre G, Arena F, et al.: Immunohistochemical detection of metallothionein in carcinomatous and normal human gastric mucosa. Histol Histopathol 2000;15:1035-1041.
    • (2000) Histol Histopathol , vol.15 , pp. 1035-1041
    • Tuccari, G.1    Giuffre, G.2    Arena, F.3
  • 34
    • 0037275807 scopus 로고    scopus 로고
    • Hypermetilation of metallothionein-3 CpG island in gastric carcinoma
    • Deng D, El-Rifai W, Ji J, et al.: Hypermetilation of metallothionein-3 CpG island in gastric carcinoma. Carcinogenesis 2003;24:25-29.
    • (2003) Carcinogenesis , vol.24 , pp. 25-29
    • Deng, D.1    El-Rifai, W.2    Ji, J.3
  • 35
    • 0030843282 scopus 로고    scopus 로고
    • Prognostic significance of the expressions of metallothionein, glutathione-S-transferase-pi, and P-glycoprotein in curatively resected gastric cancer
    • Monden N, Abe S, Sutoh I, et al.: Prognostic significance of the expressions of metallothionein, glutathione-S-transferase-pi, and P-glycoprotein in curatively resected gastric cancer. Oncology 1997;54:391-399.
    • (1997) Oncology , vol.54 , pp. 391-399
    • Monden, N.1    Abe, S.2    Sutoh, I.3
  • 36
    • 0343674631 scopus 로고    scopus 로고
    • Expression of metallothionein II in intestinal metaplasia, dysplasia, and gastric cancer
    • Ebert MP, Gunther T, Hoffman J, et al.: Expression of metallothionein II in intestinal metaplasia, dysplasia, and gastric cancer. Cancer Res 2000;60:1995-2001.
    • (2000) Cancer Res , vol.60 , pp. 1995-2001
    • Ebert, M.P.1    Gunther, T.2    Hoffman, J.3
  • 37
    • 0345276580 scopus 로고    scopus 로고
    • Metallothioneins in human tumors and potential roles in carcinogenesis
    • Cherian MG, Jayasurya A, Bay BH: Metallothioneins in human tumors and potential roles in carcinogenesis. Mutat Res 2003;533:201-209.
    • (2003) Mutat Res , vol.533 , pp. 201-209
    • Cherian, M.G.1    Jayasurya, A.2    Bay, B.H.3
  • 38
  • 39
    • 0041633801 scopus 로고    scopus 로고
    • Helicobacter pylori increases proteasome-mediated degradation of p27(kip1) in gastric epithelial cells
    • Eguchi H, Herschenhous N, Kuzushita N, et al.: Helicobacter pylori increases proteasome-mediated degradation of p27(kip1) in gastric epithelial cells. Cancer Res 2003;15:4739-4746.
    • (2003) Cancer Res , vol.15 , pp. 4739-4746
    • Eguchi, H.1    Herschenhous, N.2    Kuzushita, N.3
  • 40
    • 0038446928 scopus 로고    scopus 로고
    • Lymphocyte-rich gastric cancer: Associations with Epstein-Barr virus, microsatellite instability, histology, and survival
    • Grogg KL, Lohse CM, Pankratz VS, et al.: Lymphocyte-rich gastric cancer: Associations with Epstein-Barr virus, microsatellite instability, histology, and survival. Mod Pathol 2003;16:641-651.
    • (2003) Mod Pathol , vol.16 , pp. 641-651
    • Grogg, K.L.1    Lohse, C.M.2    Pankratz, V.S.3
  • 42
    • 0037586420 scopus 로고    scopus 로고
    • Gastric cancer: Epidemiology, pathology and treatment
    • Alberts SR, Cervantes A, van de Velde CJ: Gastric cancer: Epidemiology, pathology and treatment. Ann Oncol 2003;14:31-36.
    • (2003) Ann Oncol , vol.14 , pp. 31-36
    • Alberts, S.R.1    Cervantes, A.2    Van De Velde, C.J.3
  • 43
    • 0035818048 scopus 로고    scopus 로고
    • Chemoradiotheapy after surgery compared with surgery alone for adenocarcinoma of the stomach or gastroesophageal junction
    • Macdonald JS, Smalley SR, Benedetti J, et al.: Chemoradiotheapy after surgery compared with surgery alone for adenocarcinoma of the stomach or gastroesophageal junction. N Engl J Med 2001;345:725-730.
    • (2001) N Engl J Med , vol.345 , pp. 725-730
    • Macdonald, J.S.1    Smalley, S.R.2    Benedetti, J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.