Comparison of siRNA-induced off-target RNA and protein effects

RNA

Volumn 13, Issue 3, 2007, Pages 385-395

  Alemán, Lourdes M ^a   Doench, John ^b   Sharp, Phillip A ^a  

^a MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

Author keywords

AGO2; G:U wobble; Off target effects; siRNA; SiRNA canonical cleavage

Indexed keywords

MESSENGER RNA; SMALL INTERFERING RNA;

ARTICLE; BINDING SITE; BIOINFORMATICS; DNA CLEAVAGE; ENZYME DEGRADATION; GENE TARGETING; GENETIC TRANSFECTION; MISMATCH REPAIR; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN INTERACTION;

ANIMALS; BASE SEQUENCE; GENE EXPRESSION REGULATION; GENES, REPORTER; HUMANS; LUCIFERASES, RENILLA; MOLECULAR SEQUENCE DATA; PEPTIDE INITIATION FACTORS; PROTEIN BIOSYNTHESIS; RNA STABILITY; RNA, MESSENGER; RNA, SMALL INTERFERING; TRANSCRIPTION, GENETIC;

EID: 33847245910     PISSN: 13558382     EISSN: 14699001     Source Type: Journal    
DOI: 10.1261/rna.352507     Document Type: Article

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