BRCA1 plays a role in the hypoxic response by regulating HIF-1α stability and by modulating vascular endothelial growth factor expression

Journal of Biological Chemistry

Volumn 281, Issue 19, 2006, Pages 13047-13056

  Hyo, Jin Kang ^a   Hee, Jeong Kim ^a   Rih, Jeong Keun ^a   Mattson, Thomas L ^a   Kyu, Won Kim ^b   Cho, Chi Heum ^c   Isaacs, Jennifer S ^d   Bae, Insoo ^a  

^a GEORGETOWN UNIVERSITY   (United States)

^b Seoul National University   (South Korea)

^c Keimyung University School of Medicine   (South Korea)

^d MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL ORGANS; GENES; PATIENT TREATMENT; PROTEINS; RNA; TUMORS;

BREAST CANCER; HYPOXIC CELLS; MECHANISTIC EXPLANATION;

CELLS;

BRCA1 PROTEIN; HYPOXIA INDUCIBLE FACTOR 1BETA; SMALL INTERFERING RNA; VASCULOTROPIN;

ARTICLE; BREAST TUMOR; CELL FRACTIONATION; CELL HYPOXIA; CONTROLLED STUDY; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; PROTEIN INTERACTION; PROTEIN SECRETION; PROTEIN STABILITY; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

BRCA1 PROTEIN; CELL LINE, TUMOR; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; OXYGEN; PROMOTER REGIONS (GENETICS); TRANSCRIPTION, GENETIC; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 33744964884     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M513033200     Document Type: Article

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