A new player in the orchestra of cell growth: SREBP activity is regulated by mTORC1 and contributes to the regulation of cell and organ size

Biochemical Society Transactions

Volumn 37, Issue 1, 2009, Pages 278-283

  Porstmann, Thomas ^a,b   Santos, Claudio R ^a   Lewis, Caroline ^a   Griffiths, Beatrice ^a   Schulze, Almut ^a  

^a IMPERIAL CANCER RESEARCH FUND   (United Kingdom)

^b ETH ZURICH   (Switzerland)

Author keywords

Akt; Cell growth; Mammalian target of rapamycin complex 1 (mTORC1); Metabolism; Sterol regulatory element binding protein (SREBP)

Indexed keywords

MAMMALIAN TARGET OF RAPAMYCIN; MAMMALIAN TARGET OF RAPAMYCIN COMPLEX 1; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; STEROL REGULATORY ELEMENT BINDING PROTEIN; UNCLASSIFIED DRUG; TRANSCRIPTION FACTOR;

ARTICLE; CELL GROWTH; CELL METABOLISM; CELL SIZE; DROSOPHILA MELANOGASTER; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; GENE ACTIVITY; GENE EXPRESSION; GENE FUNCTION; GENE SYNTHESIS; GENE TARGETING; GENE TRANSLOCATION; GROWTH INHIBITION; LIPOGENESIS; NONHUMAN; ORGAN SIZE; PRIORITY JOURNAL; REGULATORY MECHANISM; TRANSCRIPTION REGULATION; ANIMAL; CELL PROLIFERATION; HUMAN; METABOLISM; REVIEW;

MAMMALIA;

ANIMALS; CELL PROLIFERATION; CELL SIZE; HUMANS; ORGAN SIZE; PROTO-ONCOGENE PROTEINS C-AKT; STEROL REGULATORY ELEMENT BINDING PROTEINS; TRANSCRIPTION FACTORS;

EID: 59749106220     PISSN: 03005127     EISSN: 14708752     Source Type: Journal    
DOI: 10.1042/BST0370278     Document Type: Article

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