-
1
-
-
0032568150
-
Stabilization of wild-type p53 by hypoxia-inducible factor 1α
-
An W.G., Kanekal M., Simon M.C., Maltepe E., Blagosklonny M.W., and Neckers L.M. Stabilization of wild-type p53 by hypoxia-inducible factor 1α. Nature 392 (1998) 405-408
-
(1998)
Nature
, vol.392
, pp. 405-408
-
-
An, W.G.1
Kanekal, M.2
Simon, M.C.3
Maltepe, E.4
Blagosklonny, M.W.5
Neckers, L.M.6
-
2
-
-
0033435198
-
Induction of hypoxia-inducible factor-1 (HIF-1) and its target genes following focal ischaemia in rat brain
-
Bergeron M., Yu A.Y., Solway K.E., Semenza G.L., and Sharp F.R. Induction of hypoxia-inducible factor-1 (HIF-1) and its target genes following focal ischaemia in rat brain. Eur. J. Neurosci. 11 (1999) 4159-4170
-
(1999)
Eur. J. Neurosci.
, vol.11
, pp. 4159-4170
-
-
Bergeron, M.1
Yu, A.Y.2
Solway, K.E.3
Semenza, G.L.4
Sharp, F.R.5
-
3
-
-
0033839757
-
Role of hypoxia-inducible factor-1 in hypoxia-induced ischemic tolerance in neonatal rat brain
-
Bergeron M., Gidday J.M., Yu A.Y., Semenza G.L., Ferriero D.M., and Sharp F.R. Role of hypoxia-inducible factor-1 in hypoxia-induced ischemic tolerance in neonatal rat brain. Ann. Neurol. 48 (2000) 285-296
-
(2000)
Ann. Neurol.
, vol.48
, pp. 285-296
-
-
Bergeron, M.1
Gidday, J.M.2
Yu, A.Y.3
Semenza, G.L.4
Ferriero, D.M.5
Sharp, F.R.6
-
4
-
-
0034255036
-
Expression of the gene encoding the proapoptotic Nip3 protein is induced by hypoxia
-
Bruick R.K. Expression of the gene encoding the proapoptotic Nip3 protein is induced by hypoxia. Proc. Natl. Acad. Sci. U.S.A. 97 (2000) 9082-9087
-
(2000)
Proc. Natl. Acad. Sci. U.S.A.
, vol.97
, pp. 9082-9087
-
-
Bruick, R.K.1
-
5
-
-
0032581277
-
Role of HIF-1alpha in hypoxia-mediated apoptosis, cell proliferation and tumour angiogenesis
-
Carmeliet P., Dor Y., Herbert J.M., Fukumura D., Brusselmans K., Dewerchin M., Neeman M., Bono F., Abramovitch R., Maxwell P., Koch C.J., Ratcliffe P., Moons L., Jain R.K., Collen D., and Keshert E. Role of HIF-1alpha in hypoxia-mediated apoptosis, cell proliferation and tumour angiogenesis. Nature 394 (1998) 485-490
-
(1998)
Nature
, vol.394
, pp. 485-490
-
-
Carmeliet, P.1
Dor, Y.2
Herbert, J.M.3
Fukumura, D.4
Brusselmans, K.5
Dewerchin, M.6
Neeman, M.7
Bono, F.8
Abramovitch, R.9
Maxwell, P.10
Koch, C.J.11
Ratcliffe, P.12
Moons, L.13
Jain, R.K.14
Collen, D.15
Keshert, E.16
-
6
-
-
0037109768
-
Activation of hypoxia-inducible factor-1 in the rat cerebral cortex after transient global ischemia: Potential role of insulin-like growth factor-1
-
Chavez J.A., and LaManna J.C. Activation of hypoxia-inducible factor-1 in the rat cerebral cortex after transient global ischemia: Potential role of insulin-like growth factor-1. J. Neurosci. 22 (2002) 8922-8931
-
(2002)
J. Neurosci.
, vol.22
, pp. 8922-8931
-
-
Chavez, J.A.1
LaManna, J.C.2
-
7
-
-
0031455410
-
The E1B 19 K/Bcl-2 binding protein Nip3 is a dimeric mitochondrial protein that activates apoptosis
-
Chen G., Ray R., Dubik D., Shi L., Cizeau J., Bleackley R.C., Saxena S., Gietz R.D., and Greenberg A.H. The E1B 19 K/Bcl-2 binding protein Nip3 is a dimeric mitochondrial protein that activates apoptosis. J. Exp. Med. 186 (1997) 1975-1983
-
(1997)
J. Exp. Med.
, vol.186
, pp. 1975-1983
-
-
Chen, G.1
Ray, R.2
Dubik, D.3
Shi, L.4
Cizeau, J.5
Bleackley, R.C.6
Saxena, S.7
Gietz, R.D.8
Greenberg, A.H.9
-
8
-
-
0032932923
-
Nix and Nip3 form a subfamily of pro-apoptotic mitochondrial proteins
-
Chen G., Cizeau J., Vande Velde C., Park J.H., Bozek G., Bolton J., Shi L., Dubik D., and Greenberg A. Nix and Nip3 form a subfamily of pro-apoptotic mitochondrial proteins. J. Biol. Chem. 264 (1999) 7-10
-
(1999)
J. Biol. Chem.
, vol.264
, pp. 7-10
-
-
Chen, G.1
Cizeau, J.2
Vande Velde, C.3
Park, J.H.4
Bozek, G.5
Bolton, J.6
Shi, L.7
Dubik, D.8
Greenberg, A.9
-
9
-
-
0038529602
-
Direct interactions between HIF-1alpha and Mdm2 modulates p53 function
-
Chen D., Li M., and Luo J. Direct interactions between HIF-1alpha and Mdm2 modulates p53 function. J. Biol. Chem. 278 (2003) 13595-13598
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 13595-13598
-
-
Chen, D.1
Li, M.2
Luo, J.3
-
10
-
-
0036905310
-
Selective blockade of endothelin-B receptors exacerbates ischemic brain damage in the rat
-
Chuquet J., Benchenane K., Toutain J., MacKenzie E.T., Roussel S., and Touzani O. Selective blockade of endothelin-B receptors exacerbates ischemic brain damage in the rat. Stroke 33 (2002) 3019-3025
-
(2002)
Stroke
, vol.33
, pp. 3019-3025
-
-
Chuquet, J.1
Benchenane, K.2
Toutain, J.3
MacKenzie, E.T.4
Roussel, S.5
Touzani, O.6
-
11
-
-
0029761644
-
Activation of vascular endothelial growth factor gene transcription by hypoxia-inducible factor 1
-
Forsythe J.A., Jiang B.H., Iyer N.V., Agani F., Leung S.W., Koos R.D., and Semenza G.L. Activation of vascular endothelial growth factor gene transcription by hypoxia-inducible factor 1. Mol. Cell. Biol. 16 (1996) 4604-4613
-
(1996)
Mol. Cell. Biol.
, vol.16
, pp. 4604-4613
-
-
Forsythe, J.A.1
Jiang, B.H.2
Iyer, N.V.3
Agani, F.4
Leung, S.W.5
Koos, R.D.6
Semenza, G.L.7
-
12
-
-
0035030534
-
Hypoxia induces the expression of the pro-apoptotic gene BNIP3
-
Guo K., Searfoss G., Krolikowski D., Pagnoni M., Franks C., Clark K., Yu K.T., and Ivashchenko Y. Hypoxia induces the expression of the pro-apoptotic gene BNIP3. Cell Death Differ. 8 (2001) 367-376
-
(2001)
Cell Death Differ.
, vol.8
, pp. 367-376
-
-
Guo, K.1
Searfoss, G.2
Krolikowski, D.3
Pagnoni, M.4
Franks, C.5
Clark, K.6
Yu, K.T.7
Ivashchenko, Y.8
-
13
-
-
0033566792
-
Hypoxia-inducible factor-1 a mediates hypoxia-induced delayed neuronal death that involves p53
-
Halterman M.W., Miller C.C., and Federoff H.J. Hypoxia-inducible factor-1 a mediates hypoxia-induced delayed neuronal death that involves p53. J. Neurosci. 19 (1999) 6818-6824
-
(1999)
J. Neurosci.
, vol.19
, pp. 6818-6824
-
-
Halterman, M.W.1
Miller, C.C.2
Federoff, H.J.3
-
14
-
-
20244378834
-
Brain-specific knock-out of hypoxia-inducible factor-1 reduces rather than increases hypoxic-ischemic damage
-
Helton R., Cui J., Scheel J.R., Ellison J.A., Ames C., Gibson C., Blouw B., Ouyang L., Dragatsis J., Zeitlin S., Johnson R.S., Lipton S.A., and Barlow C. Brain-specific knock-out of hypoxia-inducible factor-1 reduces rather than increases hypoxic-ischemic damage. J. Neurosci. 25 (2005) 4099-4107
-
(2005)
J. Neurosci.
, vol.25
, pp. 4099-4107
-
-
Helton, R.1
Cui, J.2
Scheel, J.R.3
Ellison, J.A.4
Ames, C.5
Gibson, C.6
Blouw, B.7
Ouyang, L.8
Dragatsis, J.9
Zeitlin, S.10
Johnson, R.S.11
Lipton, S.A.12
Barlow, C.13
-
15
-
-
0035917313
-
2 sensing
-
2 sensing. Science 292 (2001) 464-468
-
(2001)
Science
, vol.292
, pp. 464-468
-
-
Ivan, M.1
Kondo, K.2
Yang, H.3
Kim, W.4
Valiando, J.5
Ohh, M.6
Salic, A.7
Asara, J.M.8
Lane, W.S.9
Kaelin Jr., W.G.10
-
16
-
-
0035917808
-
2-regulated prolyl hydroxylation
-
2-regulated prolyl hydroxylation. Science 292 (2001) 468-472
-
(2001)
Science
, vol.292
, pp. 468-472
-
-
Jaakkola, P.1
Mole, D.R.2
Tian, Y.M.3
Wilson, M.I.4
Gielbert, J.5
Gaskell, S.J.6
Kriegsheim, A.7
Hebestreit, H.F.8
Mukherji, M.9
Schofield, C.J.10
Maxwell, P.H.11
Pugh, C.W.12
Ratcliffe, P.J.13
-
17
-
-
0034675037
-
Induction of vascular endothelial growth factor and hypoxia-inducible factor-1alpha by global ischemia in rat brain
-
Jin K.L., Mao X.O., Nagayama T., Goldsmith P.C., and Greenberg D.A. Induction of vascular endothelial growth factor and hypoxia-inducible factor-1alpha by global ischemia in rat brain. Neuroscience 99 (2000) 577-585
-
(2000)
Neuroscience
, vol.99
, pp. 577-585
-
-
Jin, K.L.1
Mao, X.O.2
Nagayama, T.3
Goldsmith, P.C.4
Greenberg, D.A.5
-
18
-
-
0346655211
-
BH3-only protein Noxa is a mediator of hypoxic cell death induced by hypoxia-inducible factor 1alpha
-
Kim J.Y., Ahn H.J., Ryu J.H., Suk K., and Park J.H. BH3-only protein Noxa is a mediator of hypoxic cell death induced by hypoxia-inducible factor 1alpha. J. Exp. Med. 199 (2004) 113-124
-
(2004)
J. Exp. Med.
, vol.199
, pp. 113-124
-
-
Kim, J.Y.1
Ahn, H.J.2
Ryu, J.H.3
Suk, K.4
Park, J.H.5
-
19
-
-
0043091971
-
BNIP3 plays a role in hypoxic cell death in human epithelial cells that is inhibited by growth factors EGF and IGF
-
Kothari S., Cizeau J., McMillan-Ward E., Israels S.J., Bailes M., Ens K., Kirshenbaum L.A., and Gibson S.B. BNIP3 plays a role in hypoxic cell death in human epithelial cells that is inhibited by growth factors EGF and IGF. Oncogene 22 (2003) 4734-4744
-
(2003)
Oncogene
, vol.22
, pp. 4734-4744
-
-
Kothari, S.1
Cizeau, J.2
McMillan-Ward, E.3
Israels, S.J.4
Bailes, M.5
Ens, K.6
Kirshenbaum, L.A.7
Gibson, S.B.8
-
20
-
-
0024494427
-
Reversible middle cerebral artery occlusion without craniectomy in rats
-
Longa E.Z., Weinstein P.R., Carlson S., and Cummins R. Reversible middle cerebral artery occlusion without craniectomy in rats. Stroke 20 (1989) 84-91
-
(1989)
Stroke
, vol.20
, pp. 84-91
-
-
Longa, E.Z.1
Weinstein, P.R.2
Carlson, S.3
Cummins, R.4
-
21
-
-
17644363739
-
Mechanisms of hyperbaric oxygen-induced neuroprotection in a rat model of subarachnoid hemorrhage
-
Ostrowski R.P., Colohan A.R., and Zhang J.H. Mechanisms of hyperbaric oxygen-induced neuroprotection in a rat model of subarachnoid hemorrhage. J. Cereb Blood Flow Metab. 25 (2005) 554-571
-
(2005)
J. Cereb Blood Flow Metab.
, vol.25
, pp. 554-571
-
-
Ostrowski, R.P.1
Colohan, A.R.2
Zhang, J.H.3
-
22
-
-
0038725886
-
Ischemic neuronal death in the rat hippocampus: the calpain-calpastatin-caspase hypothesis
-
Rami A. Ischemic neuronal death in the rat hippocampus: the calpain-calpastatin-caspase hypothesis. Neurobiol. Dis. 13 (2003) 75-88
-
(2003)
Neurobiol. Dis.
, vol.13
, pp. 75-88
-
-
Rami, A.1
-
23
-
-
0037411833
-
Post-ischemic activation of caspase-3 in the rat hippocampus: evidence of an axonal and dendritic localisation
-
Rami A., Jansen S., Giesser I., and Winckler J. Post-ischemic activation of caspase-3 in the rat hippocampus: evidence of an axonal and dendritic localisation. Neurochem. Int. 43 (2003) 211-223
-
(2003)
Neurochem. Int.
, vol.43
, pp. 211-223
-
-
Rami, A.1
Jansen, S.2
Giesser, I.3
Winckler, J.4
-
24
-
-
0037047647
-
Inducible expression of BNIP3 provokes mitochondrial defects and hypoxia-mediated cell death of ventricular myocytes
-
Regula K.M., Ens K., and Kirshenbaum L.A. Inducible expression of BNIP3 provokes mitochondrial defects and hypoxia-mediated cell death of ventricular myocytes. Circ. Res. 91 (2002) 226-231
-
(2002)
Circ. Res.
, vol.91
, pp. 226-231
-
-
Regula, K.M.1
Ens, K.2
Kirshenbaum, L.A.3
-
25
-
-
0035910385
-
Hypoxia death stimulus induces translocation of p53 protein to mitochondria. Detection by immunofluorescence on whole cells
-
Sansome C., Zaika A., Marchenko N.D., and Moll U.M. Hypoxia death stimulus induces translocation of p53 protein to mitochondria. Detection by immunofluorescence on whole cells. FEBS Lett. 488 (2001) 110-115
-
(2001)
FEBS Lett.
, vol.488
, pp. 110-115
-
-
Sansome, C.1
Zaika, A.2
Marchenko, N.D.3
Moll, U.M.4
-
26
-
-
0033233243
-
2 homeostasis by hypoxia-inducible factor I
-
2 homeostasis by hypoxia-inducible factor I. Annu. Rev. Cell Biol. 15 (1999) 551-578
-
(1999)
Annu. Rev. Cell Biol.
, vol.15
, pp. 551-578
-
-
Semenza, G.L.1
-
27
-
-
0001572828
-
Oxygen-regulated transcription factors and their role in pulmonary disease
-
Semenza G.L. Oxygen-regulated transcription factors and their role in pulmonary disease. Respir. Res. 1 (2000) 159-162
-
(2000)
Respir. Res.
, vol.1
, pp. 159-162
-
-
Semenza, G.L.1
-
28
-
-
2642555563
-
HIF1 and oxygen sensing in the brain
-
Sharp F.R., and Bernaudin M. HIF1 and oxygen sensing in the brain. Nat. Rev. Neurosci. 5 (2004) 437-448
-
(2004)
Nat. Rev. Neurosci.
, vol.5
, pp. 437-448
-
-
Sharp, F.R.1
Bernaudin, M.2
-
29
-
-
0035884701
-
HIF-1 dependent regulation of hypoxic induction of the cell death factors BNIP3 and NIX in human tumors
-
Sowter H.M., Ratcliffe P.J., Watson P., Greenberg A.H., and Harris A.L. HIF-1 dependent regulation of hypoxic induction of the cell death factors BNIP3 and NIX in human tumors. Cancer Res. 61 (2001) 6669-6673
-
(2001)
Cancer Res.
, vol.61
, pp. 6669-6673
-
-
Sowter, H.M.1
Ratcliffe, P.J.2
Watson, P.3
Greenberg, A.H.4
Harris, A.L.5
-
30
-
-
0036460425
-
Genomic responses of the brain to ischemic stroke. Intracerebral haemorrhage, kainate seizures, hypoglycemia, and hypoxia
-
Tang Y., Lu A., Aronow B.J., Wagner K.R., and Sharp F.R. Genomic responses of the brain to ischemic stroke. Intracerebral haemorrhage, kainate seizures, hypoglycemia, and hypoxia. Eur. J. Neurosci. 15 (2002) 1937-1952
-
(2002)
Eur. J. Neurosci.
, vol.15
, pp. 1937-1952
-
-
Tang, Y.1
Lu, A.2
Aronow, B.J.3
Wagner, K.R.4
Sharp, F.R.5
-
31
-
-
0033942613
-
BNIP3 and genetic control of necrosis-like cell death through the mitochondrial permeability transition pore
-
Vande Velde C., Cizeau J., Dubik D., Alimonti J., Brown T., Israels S., Hakem R., and Greenberg A.H. BNIP3 and genetic control of necrosis-like cell death through the mitochondrial permeability transition pore. Mol. Cell. Biol. 20 (2000) 5454-5468
-
(2000)
Mol. Cell. Biol.
, vol.20
, pp. 5454-5468
-
-
Vande Velde, C.1
Cizeau, J.2
Dubik, D.3
Alimonti, J.4
Brown, T.5
Israels, S.6
Hakem, R.7
Greenberg, A.H.8
-
32
-
-
0036256473
-
Expression of angiopoietin-2 and vascular endothelial growth factor in mice cerebral cortex after permanent focal cerebral ischemia
-
Wang R.G., and Zhu X.Z. Expression of angiopoietin-2 and vascular endothelial growth factor in mice cerebral cortex after permanent focal cerebral ischemia. Acta Pharmacol. Sin. 23 (2002) 405-411
-
(2002)
Acta Pharmacol. Sin.
, vol.23
, pp. 405-411
-
-
Wang, R.G.1
Zhu, X.Z.2
-
33
-
-
3242756656
-
Nitric oxide induces BNIP3 expression that causes cell death in macrophages
-
Yook Y.H., Kang K.H., Maeng O., Kim T.R., Lee J.O., Kang K.I., Kim Y.S., Paik S.G., and Lee H. Nitric oxide induces BNIP3 expression that causes cell death in macrophages. Biochem. Biophys. Res. Commun. 321 (2004) 298-305
-
(2004)
Biochem. Biophys. Res. Commun.
, vol.321
, pp. 298-305
-
-
Yook, Y.H.1
Kang, K.H.2
Maeng, O.3
Kim, T.R.4
Lee, J.O.5
Kang, K.I.6
Kim, Y.S.7
Paik, S.G.8
Lee, H.9
-
34
-
-
0037898897
-
BNips: a group of pro-apoptotic proteins in the Bcl-2 family
-
Zhang H.M., Cheung P., Yanagawa B., McManus B.M., and Yang D.C. BNips: a group of pro-apoptotic proteins in the Bcl-2 family. Apoptosis 8 (2003) 229-236
-
(2003)
Apoptosis
, vol.8
, pp. 229-236
-
-
Zhang, H.M.1
Cheung, P.2
Yanagawa, B.3
McManus, B.M.4
Yang, D.C.5
|