Brain-specific knock-out of hypoxia-inducible factor-1α reduces rather than increases hypoxic-ischemic damage

Journal of Neuroscience

Volumn 25, Issue 16, 2005, Pages 4099-4107

  Helton, Rob ^a   Cui, Jiankun ^b   Scheel, John R ^a   Ellison, Julie A ^a   Ames, Chris ^a   Gibson, Claire ^b   Blouw, Barbara ^c   Ouyang, Ling ^a   Dragatsis, Ioannis ^d   Zeitlin, Scott ^e   Johnson, Randall S ^c   Lipton, Stuart A ^b   Barlow, Carrolee ^a  

^a SALK INSTITUTE FOR BIOLOGICAL STUDIES   (United States)

^b BURNHAM INSTITUTE   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d UNIVERSITY OF TENNESSEE HEALTH SCIENCE CENTER   (United States)

^e UNIVERSITY OF VIRGINIA   (United States)

Author keywords

Apoptosis; Carotid; Hippocampus; Hypoxia; Neuron; Transcription

Indexed keywords

HYPOXIA INDUCIBLE FACTOR 1ALPHA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BRAIN CORTEX; BRAIN HYPOXIA; BRAIN ISCHEMIA; CELL SURVIVAL; CONTROLLED STUDY; DOWN REGULATION; GENE DELETION; GENE EXPRESSION REGULATION; GENETIC TRANSCRIPTION; HIPPOCAMPUS; MOUSE; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL;

ANIMALS; APOPTOSIS; BLOTTING, SOUTHERN; CELL COUNT; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN; FLUORESCENT ANTIBODY TECHNIQUE; GENE DELETION; GENE EXPRESSION REGULATION; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; HYPOXIA-ISCHEMIA, BRAIN; IN SITU NICK-END LABELING; MICE; MICE, KNOCKOUT; MICROARRAY ANALYSIS; MODELS, BIOLOGICAL; PROTEIN-SERINE-THREONINE KINASES;

EID: 20244378834     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.4555-04.2005     Document Type: Article

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