Protective effect of vitamin E against focal brain ischemia and neuronal death through induction of target genes of hypoxia-inducible factor-1

Neuroscience

Volumn 126, Issue 2, 2004, Pages 433-440

  Zhang, B ^a,b   Tanaka, J ^a   Yang, L ^a,b   Sakanaka, M ^a   Hata, R ^a   Maeda, N ^a   Mitsuda, N ^a  

^a EHIME UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b UNIVERSITY OF KANSAS MEDICAL CENTER   (United States)

Author keywords

BBB; blood brain barrier; dimethyl sulfoxide; DMSO; EPO; erythropoietin; HIF 1; HO ; HO 1; hydroxyl radicals; hypoxia inducible factor 1; middle cerebral artery occlusion; promoter activity; transcription factor; vascular endothelial growth factor

Indexed keywords

ALPHA TOCOPHEROL; HEME OXYGENASE 1; HYPOXIA INDUCIBLE FACTOR 1; NITRIC OXIDE; VASCULOTROPIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; BLOOD BRAIN BARRIER; BRAIN HYPOXIA; BRAIN INFARCTION; BRAIN ISCHEMIA; BRAIN TISSUE; CELL CULTURE; CONTROLLED STUDY; DRUG EFFECT; EMBRYO; GENE ACTIVATION; GENE INDUCTION; MALE; MIDDLE CEREBRAL ARTERY OCCLUSION; NERVE CELL; NERVE CELL NECROSIS; NEUROPROTECTION; NEWBORN; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; RAT; STATISTICAL SIGNIFICANCE;

ANIMALS; ANTIOXIDANTS; BRAIN ISCHEMIA; CELL DEATH; DNA-BINDING PROTEINS; DOSE-RESPONSE RELATIONSHIP, DRUG; ESCAPE REACTION; HEAT-SHOCK PROTEINS; HEME OXYGENASE (DECYCLIZING); HYPOXIA-INDUCIBLE FACTOR 1; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; MALE; NEURONS; NEUROPROTECTIVE AGENTS; NUCLEAR PROTEINS; OXYGENASES; RATS; RATS, INBRED SHR; TRANSCRIPTION FACTORS; VASCULAR ENDOTHELIAL GROWTH FACTOR A; VITAMIN E;

EID: 2942677080     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuroscience.2004.03.057     Document Type: Article

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