-
1
-
-
0842281551
-
Principles of protein folding, misfolding and aggregation
-
Dobson, C. M. 2004. Principles of protein folding, misfolding and aggregation. Semin. Cell Dev. Biol. 15:3-16.
-
(2004)
Semin. Cell Dev. Biol
, vol.15
, pp. 3-16
-
-
Dobson, C.M.1
-
2
-
-
27644596641
-
Opinion: What is the role of protein aggregation in neurodegeneration?
-
Ross, C. A., and M. A. Poirier. 2005. Opinion: what is the role of protein aggregation in neurodegeneration? Nat. Rev. Mol. Cell Biol. 6:891-898.
-
(2005)
Nat. Rev. Mol. Cell Biol
, vol.6
, pp. 891-898
-
-
Ross, C.A.1
Poirier, M.A.2
-
3
-
-
0037264120
-
Unfolding the role of protein misfolding in neurodegenerative diseases
-
Soto, C. 2003. Unfolding the role of protein misfolding in neurodegenerative diseases. Nat. Rev. Neurosci. 4:49-60.
-
(2003)
Nat. Rev. Neurosci
, vol.4
, pp. 49-60
-
-
Soto, C.1
-
4
-
-
0037015081
-
Huntington's disease age-of-onset linked to polyglutamine aggregation nucleation
-
Chen, S., F. A. Ferrone, and R. Wetzel. 2002. Huntington's disease age-of-onset linked to polyglutamine aggregation nucleation. Proc. Natl. Acad. Sci. USA. 99:11884-11889.
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 11884-11889
-
-
Chen, S.1
Ferrone, F.A.2
Wetzel, R.3
-
5
-
-
0033551063
-
Self-assembly of polyglutamine-containing huntingtin fragments into amyloid-like fibrils: Implications for Huntington's disease pathology
-
Scherzinger, E., A. Sittler, K. Schweiger, V. Heiser, R. Lurz, R. Hasenbank, G. P. Bates, H. Lehrach, and E. E. Wanker. 1999. Self-assembly of polyglutamine-containing huntingtin fragments into amyloid-like fibrils: implications for Huntington's disease pathology. Proc. Natl. Acad. Sci. USA. 96:4604-4609.
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 4604-4609
-
-
Scherzinger, E.1
Sittler, A.2
Schweiger, K.3
Heiser, V.4
Lurz, R.5
Hasenbank, R.6
Bates, G.P.7
Lehrach, H.8
Wanker, E.E.9
-
6
-
-
0036850529
-
Aggregated polyglutamine peptides delivered to nuclei are toxic to mammalian cells
-
Yang, W., J. R. Dunlap, R. B. Andrews, and R. Wetzel. 2002. Aggregated polyglutamine peptides delivered to nuclei are toxic to mammalian cells. Hum. Mol. Genet. 11:2905-2917.
-
(2002)
Hum. Mol. Genet
, vol.11
, pp. 2905-2917
-
-
Yang, W.1
Dunlap, J.R.2
Andrews, R.B.3
Wetzel, R.4
-
7
-
-
0033791230
-
Protein aggregation and pathogenesis of Huntington's disease: Mechanisms and correlations
-
Wanker, E. E. 2000. Protein aggregation and pathogenesis of Huntington's disease: mechanisms and correlations. Biol. Chem. 381:937-942.
-
(2000)
Biol. Chem
, vol.381
, pp. 937-942
-
-
Wanker, E.E.1
-
8
-
-
33746656653
-
A network of protein interactions determines polyglutamine toxicity
-
Duennwald, M. L., S. Jagadish, F. Giorgini, P. J. Muchowski, and S. Lindquist. 2006. A network of protein interactions determines polyglutamine toxicity. Proc. Natl. Acad. Sci. USA. 103:11051-11056.
-
(2006)
Proc. Natl. Acad. Sci. USA
, vol.103
, pp. 11051-11056
-
-
Duennwald, M.L.1
Jagadish, S.2
Giorgini, F.3
Muchowski, P.J.4
Lindquist, S.5
-
9
-
-
33746635502
-
Flanking sequences profoundly alter polyglutamine toxicity in yeast
-
Duennwald, M. L., S. Jagadish, P. J. Muchowski, and S. Lindquist. 2006. Flanking sequences profoundly alter polyglutamine toxicity in yeast. Proc. Natl. Acad. Sci. USA. 103:11045-11050.
-
(2006)
Proc. Natl. Acad. Sci. USA
, vol.103
, pp. 11045-11050
-
-
Duennwald, M.L.1
Jagadish, S.2
Muchowski, P.J.3
Lindquist, S.4
-
10
-
-
0035968933
-
Amino acid sequences flanking polyglutamine stretches influence their potential for aggregate formation
-
Nozaki, K., O. Onodera, H. Takano, and S. Tsuji. 2001. Amino acid sequences flanking polyglutamine stretches influence their potential for aggregate formation. Neuroreport. 12:3357-3364.
-
(2001)
Neuroreport
, vol.12
, pp. 3357-3364
-
-
Nozaki, K.1
Onodera, O.2
Takano, H.3
Tsuji, S.4
-
11
-
-
33846540080
-
The first 17 amino acids of huntingtin modulate its sub-cellular localization, aggregation and effects on calcium homeostasis
-
Rockabrand, E., N. Slepko, A. Pantalone, V. N. Nukala, A. Kazantsev, J. L. Marsh, P. G. Sullivan, J. S. Steffan, S. L. Sensi, and L. M. Thompson. 2007. The first 17 amino acids of huntingtin modulate its sub-cellular localization, aggregation and effects on calcium homeostasis. Hum. Mol. Genet. 16:61-77.
-
(2007)
Hum. Mol. Genet
, vol.16
, pp. 61-77
-
-
Rockabrand, E.1
Slepko, N.2
Pantalone, A.3
Nukala, V.N.4
Kazantsev, A.5
Marsh, J.L.6
Sullivan, P.G.7
Steffan, J.S.8
Sensi, S.L.9
Thompson, L.M.10
-
12
-
-
0035976953
-
The role of protein composition in specifying nuclear inclusion formation in polyglutamine disease
-
Chai, Y., L. Wu, J. D. Griffin, and H. L. Paulson. 2001. The role of protein composition in specifying nuclear inclusion formation in polyglutamine disease. J. Biol. Chem. 276:44889-44897.
-
(2001)
J. Biol. Chem
, vol.276
, pp. 44889-44897
-
-
Chai, Y.1
Wu, L.2
Griffin, J.D.3
Paulson, H.L.4
-
13
-
-
7144253143
-
Truncated N-terminal fragments of huntingtin with expanded glutamine repeats form nuclear and cytoplasmic aggregates in cell culture
-
Cooper, J. K., G. Schilling, M. F. Peters, W. J. Herring, A. H. Sharp, Z. Kaminsky, J. Masone, F. A. Khan, M. Delanoy, D. R. Borchelt, V. L. Dawson, T. M. Dawson, and C. A. Ross. 1998. Truncated N-terminal fragments of huntingtin with expanded glutamine repeats form nuclear and cytoplasmic aggregates in cell culture. Hum. Mol. Genet. 7:783-790.
-
(1998)
Hum. Mol. Genet
, vol.7
, pp. 783-790
-
-
Cooper, J.K.1
Schilling, G.2
Peters, M.F.3
Herring, W.J.4
Sharp, A.H.5
Kaminsky, Z.6
Masone, J.7
Khan, F.A.8
Delanoy, M.9
Borchelt, D.R.10
Dawson, V.L.11
Dawson, T.M.12
Ross, C.A.13
-
14
-
-
32144436256
-
Proteolytic cleavage of polyglutamine-expanded ataxin-3 is critical for aggregation and sequestration of non-expanded ataxin-3
-
Haacke, A., S. A. Broadley, R. Boteva, N. Tzvetkov, F. U. Hartl, and P. Breuer. 2006. Proteolytic cleavage of polyglutamine-expanded ataxin-3 is critical for aggregation and sequestration of non-expanded ataxin-3. Hum. Mol. Genet. 15:555-568.
-
(2006)
Hum. Mol. Genet
, vol.15
, pp. 555-568
-
-
Haacke, A.1
Broadley, S.A.2
Boteva, R.3
Tzvetkov, N.4
Hartl, F.U.5
Breuer, P.6
-
15
-
-
34047269594
-
Soluble androgen receptor oligomers underlie pathology in a mouse model of spinobulbar muscular atrophy
-
Li, M., E. S. Chevalier-Larsen, D. E. Merry, and M. I. Diamond. 2007. Soluble androgen receptor oligomers underlie pathology in a mouse model of spinobulbar muscular atrophy. J. Biol. Chem. 282:3157-3164.
-
(2007)
J. Biol. Chem
, vol.282
, pp. 3157-3164
-
-
Li, M.1
Chevalier-Larsen, E.S.2
Merry, D.E.3
Diamond, M.I.4
-
16
-
-
0033080367
-
Glutamine repeats and neurodegenerative diseases: Molecular aspects
-
Perutz, M. F. 1999. Glutamine repeats and neurodegenerative diseases: molecular aspects. Trends Biochem. Sci. 24:58-63.
-
(1999)
Trends Biochem. Sci
, vol.24
, pp. 58-63
-
-
Perutz, M.F.1
-
17
-
-
9144264986
-
Polyglutamine expansion in ataxin-3 does not affect protein stability: Implications for misfolding and disease
-
Chow, M. K., A. M. Ellisdon, L. D. Cabrita, and S. P. Bottomley. 2004. Polyglutamine expansion in ataxin-3 does not affect protein stability: implications for misfolding and disease. J. Biol. Chem. 279:47643-47651.
-
(2004)
J. Biol. Chem
, vol.279
, pp. 47643-47651
-
-
Chow, M.K.1
Ellisdon, A.M.2
Cabrita, L.D.3
Bottomley, S.P.4
-
18
-
-
0345118103
-
Destabilization of a non-pathological variant of ataxin-3 results in fibrillogenesis via a partially folded intermediate: A model for misfolding in polyglutamine disease
-
Chow, M. K., H. L. Paulson, and S. P. Bottomley. 2004. Destabilization of a non-pathological variant of ataxin-3 results in fibrillogenesis via a partially folded intermediate: a model for misfolding in polyglutamine disease. J. Mol. Biol. 335:333-341.
-
(2004)
J. Mol. Biol
, vol.335
, pp. 333-341
-
-
Chow, M.K.1
Paulson, H.L.2
Bottomley, S.P.3
-
19
-
-
33744952750
-
Extended polyglutamine tracts cause aggregation and structural perturbation of an adjacent β barrel protein
-
Ignatova, Z., and L. M. Gierasch. 2006. Extended polyglutamine tracts cause aggregation and structural perturbation of an adjacent β barrel protein. J. Biol. Chem. 281:12959-12967.
-
(2006)
J. Biol. Chem
, vol.281
, pp. 12959-12967
-
-
Ignatova, Z.1
Gierasch, L.M.2
-
20
-
-
0035976971
-
Intra- and intermolecular β-pleated sheet formation in glutamine-repeat inserted myoglobin as a model for polyglutamine diseases
-
Tanaka, M., I. Morishima, T. Akagi, T. Hashikawa, and N. Nukina. 2001. Intra- and intermolecular β-pleated sheet formation in glutamine-repeat inserted myoglobin as a model for polyglutamine diseases. J. Biol. Chem. 276:45470-45475.
-
(2001)
J. Biol. Chem
, vol.276
, pp. 45470-45475
-
-
Tanaka, M.1
Morishima, I.2
Akagi, T.3
Hashikawa, T.4
Nukina, N.5
-
21
-
-
6044269458
-
Structural and functional analysis of the Josephin domain of the polyglutamine protein ataxin-3
-
Chow, M. K., J. P. Mackay, J. C. Whisstock, M. J. Scanlon, and S. P. Bottomley. 2004. Structural and functional analysis of the Josephin domain of the polyglutamine protein ataxin-3. Biochem. Biophys. Res. Commun. 322:387-394.
-
(2004)
Biochem. Biophys. Res. Commun
, vol.322
, pp. 387-394
-
-
Chow, M.K.1
Mackay, J.P.2
Whisstock, J.C.3
Scanlon, M.J.4
Bottomley, S.P.5
-
22
-
-
8544260320
-
Characterization of the structure and the amyloidogenic properties of the Josephin domain of the polyglutamine-containing protein ataxin-3
-
Masino, L., G. Nicastro, R. P. Menon, F. Dal Piaz, L. Calder, and A. Pastore. 2004. Characterization of the structure and the amyloidogenic properties of the Josephin domain of the polyglutamine-containing protein ataxin-3. J. Mol. Biol. 344:1021-1035.
-
(2004)
J. Mol. Biol
, vol.344
, pp. 1021-1035
-
-
Masino, L.1
Nicastro, G.2
Menon, R.P.3
Dal Piaz, F.4
Calder, L.5
Pastore, A.6
-
23
-
-
28944446477
-
Oligoproline effects on polyglutamine conformation and aggregation
-
Bhattacharyya, A., A. K. Thakur, V. M. Chellgren, G. Thiagarajan, A. D. Williams, B. W. Chellgren, T. P. Creamer, and R. Wetzel. 2006. Oligoproline effects on polyglutamine conformation and aggregation. J. Mol. Biol. 355:524-535.
-
(2006)
J. Mol. Biol
, vol.355
, pp. 524-535
-
-
Bhattacharyya, A.1
Thakur, A.K.2
Chellgren, V.M.3
Thiagarajan, G.4
Williams, A.D.5
Chellgren, B.W.6
Creamer, T.P.7
Wetzel, R.8
-
24
-
-
17844383699
-
Functional insights from the distribution and role of homopeptide repeat-containing proteins
-
Faux, N. G., S. P. Bottomley, A. M. Lesk, J. A. Irving, J. R. Morrison, M. G. de la Banda, and J. C. Whisstock. 2005. Functional insights from the distribution and role of homopeptide repeat-containing proteins. Genome Res. 15:537-551.
-
(2005)
Genome Res
, vol.15
, pp. 537-551
-
-
Faux, N.G.1
Bottomley, S.P.2
Lesk, A.M.3
Irving, J.A.4
Morrison, J.R.5
de la Banda, M.G.6
Whisstock, J.C.7
-
25
-
-
33645471986
-
A family of E. coli expression vectors for laboratory scale and high throughput soluble protein production
-
Cabrita, L. D., W. Dai, and S. P. Bottomley. 2006. A family of E. coli expression vectors for laboratory scale and high throughput soluble protein production. BMC Biotechnol. 6:12.
-
(2006)
BMC Biotechnol
, vol.6
, pp. 12
-
-
Cabrita, L.D.1
Dai, W.2
Bottomley, S.P.3
-
26
-
-
0032692386
-
Preparation of human cDNas encoding expanded polyglutamine repeats
-
Peters, M. F., and C. A. Ross. 1999. Preparation of human cDNas encoding expanded polyglutamine repeats. Neurosci. Lett. 275:129-132.
-
(1999)
Neurosci. Lett
, vol.275
, pp. 129-132
-
-
Peters, M.F.1
Ross, C.A.2
-
27
-
-
14844294424
-
Protein production by auto-induction in high density shaking cultures
-
Studier, F. W. 2005. Protein production by auto-induction in high density shaking cultures. Protein Expr. Purif. 41:207-234.
-
(2005)
Protein Expr. Purif
, vol.41
, pp. 207-234
-
-
Studier, F.W.1
-
28
-
-
0034992645
-
A method for efficient isotopic labeling of recombinant proteins
-
Marley, J., M. Lu, and C. Bracken. 2001. A method for efficient isotopic labeling of recombinant proteins. J. Biomol. NMR. 20:71-75.
-
(2001)
J. Biomol. NMR
, vol.20
, pp. 71-75
-
-
Marley, J.1
Lu, M.2
Bracken, C.3
-
29
-
-
0036168995
-
DICHROWEB: An interactive website for the analysis of protein secondary structure from circular dichroism spectra
-
Lobley, A., L. Whitmore, and B. A. Wallace. 2002. DICHROWEB: an interactive website for the analysis of protein secondary structure from circular dichroism spectra. Bioinformatics. 18:211-212.
-
(2002)
Bioinformatics
, vol.18
, pp. 211-212
-
-
Lobley, A.1
Whitmore, L.2
Wallace, B.A.3
-
30
-
-
0034615932
-
Inhibition of polyglutamine protein aggregation and cell death by novel peptides identified by phage display screening
-
Nagai, Y., T. Tucker, H. Ren, D. J. Kenan, B. S. Henderson, J. D. Keene, W. J. Strittmatter, and J. R. Burke. 2000. Inhibition of polyglutamine protein aggregation and cell death by novel peptides identified by phage display screening. J. Biol. Chem. 275:10437-10442.
-
(2000)
J. Biol. Chem
, vol.275
, pp. 10437-10442
-
-
Nagai, Y.1
Tucker, T.2
Ren, H.3
Kenan, D.J.4
Henderson, B.S.5
Keene, J.D.6
Strittmatter, W.J.7
Burke, J.R.8
-
31
-
-
33745195252
-
The two-stage pathway of ataxin-3 fibrillogenesis involves a polyglutamine-independent step
-
Ellisdon, A. M., B. Thomas, and S. P. Bottomley. 2006. The two-stage pathway of ataxin-3 fibrillogenesis involves a polyglutamine-independent step. J. Biol. Chem. 281:16888-16896.
-
(2006)
J. Biol. Chem
, vol.281
, pp. 16888-16896
-
-
Ellisdon, A.M.1
Thomas, B.2
Bottomley, S.P.3
-
32
-
-
0347722841
-
Heteronuclear multidimensional NMR experiments for the structure determination of proteins in solution employing pulsed field gradients
-
Sattler, M., J. Schleucher, and C. Griesinger. 1999. Heteronuclear multidimensional NMR experiments for the structure determination of proteins in solution employing pulsed field gradients. Prog. Nucl. Magn. Reson. Spectrosc. 34:93-158.
-
(1999)
Prog. Nucl. Magn. Reson. Spectrosc
, vol.34
, pp. 93-158
-
-
Sattler, M.1
Schleucher, J.2
Griesinger, C.3
-
33
-
-
0006925492
-
Pure absorption gradient enhanced heteronuclear single quantum correlation spectroscopy with improved sensitivity
-
Kay, L. E., P. Keifer, and P. Saarinen. 1992. Pure absorption gradient enhanced heteronuclear single quantum correlation spectroscopy with improved sensitivity. J. Am. Chem. Soc. 114:10663-10665.
-
(1992)
J. Am. Chem. Soc
, vol.114
, pp. 10663-10665
-
-
Kay, L.E.1
Keifer, P.2
Saarinen, P.3
-
34
-
-
0029400480
-
NMRPipe: A multidimensional spectral processing system based on UNIX pipes
-
Delaglio, F., S. Grzesiek, G. W. Vuister, G. Zhu, J. Pfeifer, and A. Bax. 1995. NMRPipe: a multidimensional spectral processing system based on UNIX pipes. J. Biomol. NMR. 6:277-293.
-
(1995)
J. Biomol. NMR
, vol.6
, pp. 277-293
-
-
Delaglio, F.1
Grzesiek, S.2
Vuister, G.W.3
Zhu, G.4
Pfeifer, J.5
Bax, A.6
-
35
-
-
0036308102
-
Protein NMR structure determination with automated NOE assignment using the new software CANDID and the torsion angle dynamics algorithm DYANA
-
Herrmann, T., P. Guntert, and K. Wuthrich. 2002. Protein NMR structure determination with automated NOE assignment using the new software CANDID and the torsion angle dynamics algorithm DYANA. J. Mol. Biol. 319:209-227.
-
(2002)
J. Mol. Biol
, vol.319
, pp. 209-227
-
-
Herrmann, T.1
Guntert, P.2
Wuthrich, K.3
-
36
-
-
0033003335
-
Protein backbone angle restraints from searching a database for chemical shift and sequence homology
-
Cornilescu, G., F. Delaglio, and A. Bax. 1999. Protein backbone angle restraints from searching a database for chemical shift and sequence homology. J. Biomol. NMR. 13:289-302.
-
(1999)
J. Biomol. NMR
, vol.13
, pp. 289-302
-
-
Cornilescu, G.1
Delaglio, F.2
Bax, A.3
-
37
-
-
0013293280
-
The Xplor-NIH NMR molecular structure determination package
-
Schwieters, C. D., J. J. Kuszewski, N. Tjandra, and G. M. Clore. 2003. The Xplor-NIH NMR molecular structure determination package. J. Magn. Reson. 160:65-73.
-
(2003)
J. Magn. Reson
, vol.160
, pp. 65-73
-
-
Schwieters, C.D.1
Kuszewski, J.J.2
Tjandra, N.3
Clore, G.M.4
-
38
-
-
0031989849
-
Accurate quantitation of water-amide proton exchange rates using the phase-modulated CLEAN chemical EXchange (CLEANEX-PM) approach with a Fast-HSQC (FHSQC) detection scheme
-
Hwang, T. L., P. C. van Zijl, and S. Mori. 1998. Accurate quantitation of water-amide proton exchange rates using the phase-modulated CLEAN chemical EXchange (CLEANEX-PM) approach with a Fast-HSQC (FHSQC) detection scheme. J. Biomol. NMR. 11:221-226.
-
(1998)
J. Biomol. NMR
, vol.11
, pp. 221-226
-
-
Hwang, T.L.1
van Zijl, P.C.2
Mori, S.3
-
39
-
-
0028608099
-
The stability and unfolding of an IgG binding protein based upon the B domain of protein A from Staphylococcus aureus probed by tryptophan substitution and fluorescence spectroscopy
-
Bottomley, S. P., A. G. Popplewell, M. Scawen, T. Wan, B. J. Sutton, and M. G. Gore. 1994. The stability and unfolding of an IgG binding protein based upon the B domain of protein A from Staphylococcus aureus probed by tryptophan substitution and fluorescence spectroscopy. Protein Eng. 7:1463-1470.
-
(1994)
Protein Eng
, vol.7
, pp. 1463-1470
-
-
Bottomley, S.P.1
Popplewell, A.G.2
Scawen, M.3
Wan, T.4
Sutton, B.J.5
Gore, M.G.6
-
40
-
-
2342449128
-
Testing protein-folding simulations by experiment: B domain of protein A
-
Sato, S., T. L. Religa, V. Daggett, and A. R. Fersht. 2004. Testing protein-folding simulations by experiment: B domain of protein A. Proc. Natl. Acad. Sci. USA. 101:6952-6956.
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 6952-6956
-
-
Sato, S.1
Religa, T.L.2
Daggett, V.3
Fersht, A.R.4
-
41
-
-
0025196843
-
Sequential 1H NMR assignments and secondary structure of the B domain of staphylococcal protein A: Structural changes between the free B domain in solution and the Fc-bound B domain in crystal
-
Torigoe, H., I. Shimada, A. Saito, M. Sato, and Y. Arata. 1990. Sequential 1H NMR assignments and secondary structure of the B domain of staphylococcal protein A: structural changes between the free B domain in solution and the Fc-bound B domain in crystal. Biochemistry. 29:8787-8793.
-
(1990)
Biochemistry
, vol.29
, pp. 8787-8793
-
-
Torigoe, H.1
Shimada, I.2
Saito, A.3
Sato, M.4
Arata, Y.5
-
42
-
-
34447269734
-
Pathogenic and non-pathogenic polyglutamine tracts have similar structural properties: Towards a length-dependent toxicity gradient
-
Klein, F. A., A. Pastore, L. Masino, G. Zeder-Lutz, H. Nierengarten, M. Oulad-Abdelghani, D. Altschuh, J. L. Mandel, and Y. Trottier. 2007. Pathogenic and non-pathogenic polyglutamine tracts have similar structural properties: towards a length-dependent toxicity gradient. J. Mol. Biol. 371:235-244.
-
(2007)
J. Mol. Biol
, vol.371
, pp. 235-244
-
-
Klein, F.A.1
Pastore, A.2
Masino, L.3
Zeder-Lutz, G.4
Nierengarten, H.5
Oulad-Abdelghani, M.6
Altschuh, D.7
Mandel, J.L.8
Trottier, Y.9
-
43
-
-
33947586837
-
Mechanisms of ataxin-3 misfolding and fibril formation: Kinetic analysis of a disease-associated polyglutamine protein
-
Ellisdon, A. M., M. C. Pearce, and S. P. Bottomley. 2007. Mechanisms of ataxin-3 misfolding and fibril formation: kinetic analysis of a disease-associated polyglutamine protein. J. Mol. Biol. 368:595-605.
-
(2007)
J. Mol. Biol
, vol.368
, pp. 595-605
-
-
Ellisdon, A.M.1
Pearce, M.C.2
Bottomley, S.P.3
-
44
-
-
0027261537
-
Relationship between trinucleotide repeat expansion and phenotypic variation in Huntington's disease
-
Snell, R. G., J. C. MacMillan, J. P. Cheadle, I. Fenton, L. P. Lazarou, P. Davies, M. E. MacDonald, J. F. Gusella, P. S. Harper, and D. J. Shaw. 1993. Relationship between trinucleotide repeat expansion and phenotypic variation in Huntington's disease. Nat. Genet. 4:393-397.
-
(1993)
Nat. Genet
, vol.4
, pp. 393-397
-
-
Snell, R.G.1
MacMillan, J.C.2
Cheadle, J.P.3
Fenton, I.4
Lazarou, L.P.5
Davies, P.6
MacDonald, M.E.7
Gusella, J.F.8
Harper, P.S.9
Shaw, D.J.10
-
45
-
-
0031576337
-
Glutamine, alanine or glycine repeats inserted into the loop of a protein have minimal effects on stability and folding rates
-
Ladurner, A. G., and A. R. Fersht. 1997. Glutamine, alanine or glycine repeats inserted into the loop of a protein have minimal effects on stability and folding rates. J. Mol. Biol. 273:330-337.
-
(1997)
J. Mol. Biol
, vol.273
, pp. 330-337
-
-
Ladurner, A.G.1
Fersht, A.R.2
-
46
-
-
0031056829
-
Instability, unfolding and aggregation of human lysozyme variants underlying amyloid fibrillogenesis
-
Booth, D. R., M. Sunde, V. Bellotti, C. V. Robinson, W. L. Hutchinson, P. E. Fraser, P. N. Hawkins, C. M. Dobson, S. E. Radford, C. C. Blake, and M. B. Pepys. 1997. Instability, unfolding and aggregation of human lysozyme variants underlying amyloid fibrillogenesis. Nature. 385:787-793.
-
(1997)
Nature
, vol.385
, pp. 787-793
-
-
Booth, D.R.1
Sunde, M.2
Bellotti, V.3
Robinson, C.V.4
Hutchinson, W.L.5
Fraser, P.E.6
Hawkins, P.N.7
Dobson, C.M.8
Radford, S.E.9
Blake, C.C.10
Pepys, M.B.11
-
47
-
-
0037058942
-
Sequence-dependent denaturation energetics: A major determinant in amyloid disease diversity
-
Hammarstrom, P., X. Jiang, A. R. Hurshman, E. T. Powers, and J. W. Kelly. 2002. Sequence-dependent denaturation energetics: a major determinant in amyloid disease diversity. Proc. Natl. Acad. Sci. USA. 99(Suppl 4):16427-16432.
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, Issue.SUPPL. 4
, pp. 16427-16432
-
-
Hammarstrom, P.1
Jiang, X.2
Hurshman, A.R.3
Powers, E.T.4
Kelly, J.W.5
-
48
-
-
0036841958
-
Protein aggregation in disease: A role for folding intermediates forming specific multimeric interactions
-
Horwich, A. 2002. Protein aggregation in disease: a role for folding intermediates forming specific multimeric interactions. J. Clin. Invest. 110:1221-1232.
-
(2002)
J. Clin. Invest
, vol.110
, pp. 1221-1232
-
-
Horwich, A.1
-
49
-
-
0033574161
-
Influence of amino acid substitutions related to inherited human prion diseases on the thermodynamic stability of the cellular prion protein
-
Liemann, S., and R. Glockshuber. 1999. Influence of amino acid substitutions related to inherited human prion diseases on the thermodynamic stability of the cellular prion protein. Biochemistry. 38:3258-3267.
-
(1999)
Biochemistry
, vol.38
, pp. 3258-3267
-
-
Liemann, S.1
Glockshuber, R.2
-
50
-
-
0032553530
-
Familial mutations and the thermodynamic stability of the recombinant human prion protein
-
Swietnicki, W., R. B. Petersen, P. Gambetti, and W. K. Surewicz. 1998. Familial mutations and the thermodynamic stability of the recombinant human prion protein. J. Biol. Chem. 273:31048-31052.
-
(1998)
J. Biol. Chem
, vol.273
, pp. 31048-31052
-
-
Swietnicki, W.1
Petersen, R.B.2
Gambetti, P.3
Surewicz, W.K.4
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