Preparation of human cDNAs encoding expanded polyglutamine repeats

Neuroscience Letters

Volumn 275, Issue 2, 1999, Pages 129-132

  Peters, Matthew F ^a   Ross, Christopher A ^a,b,c  

^a Molecular Neurobiology   (United States)

^b JOHNS HOPKINS UNIVERSITY   (United States)

^c JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

CAG repeat; Huntington's disease; Polyglutamine; Trinulceotide repeat; Type IIS restriction enzyme

Indexed keywords

GLUTAMINE DERIVATIVE; POLYGLUTAMINE; UNCLASSIFIED DRUG;

ARTICLE; DNA DETERMINATION; HUMAN; HUNTINGTON CHOREA; NUCLEOTIDE SEQUENCE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; TRINUCLEOTIDE REPEAT;

DNA, COMPLEMENTARY; GLUTAMINE; HUMANS; HUNTINGTON DISEASE; MYOCLONIC EPILEPSIES, PROGRESSIVE; POLYMERASE CHAIN REACTION; TRINUCLEOTIDE REPEAT EXPANSION; TRINUCLEOTIDE REPEATS;

EID: 0032692386     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3940(99)00758-2     Document Type: Article

References (12)

1. Cooper J.K., Schilling G., Peters M.F., Herring W.J., Sharp A.H., Kaminsky Z., Masone J., Khan F.A., Delanoy M., Borchelt D.R., Dawson V.L., Dawson T.M., Ross C.A. Truncated N-terminal fragments of huntingtin with expanded glutamine repeats form nuclear and cytoplasmic aggregates in cell culture. Hum. Mol. Genet. 7:1998;783-790.
2. Kang S., Ohshima K., Jaworski A., Wells R.D. CTG triplet repeats from the myotonic dystrophy gene are expanded in Escherichia coli distal to the replication origin as a single large event. J. Mol. Biol. 258:1996;543-547.
3. Li S.H., Cheng A.L., Li X.J. Cellular defects and altered gene expression in PC12 cells stably expressing mutant huntingtin. J. Neurosci. 19:1999;5159-5172.
4. Mangiarini L., Sathasivam K., Mahal A., Mott R., Seller M., Bates G.P. Instability of highly expanded CAG repeats in mice transgenic for the Huntington's disease mutation. Nat. Genet. 15:1997;197-200.
5. Ohshima K., Kang S., Wells R.D. CTG triplet repeats from human hereditary diseases are dominant genetic expansion products in Escherichia coli. J. Biol. Chem. 271:1996;1853-1856.
6. Ordway J.M., Detloff P.J. In vitro synthesis and cloning of long CAG repeats. Biotechniques. 21:1996;609-612.
7. Ross C.A. Intranuclear neuronal inclusions: a common pathogenic mechanism for glutamine-repeat neurodegenerative diseases? Neuron. 19:1997;1147-1150.
8. Sarkar P.S., Chang H.C., Boudi F.B., Reddy S. CTG repeats show bimodal amplification in E. coli. Cell. 95:1998;531-540.
9. Sathasivam K., Amaechi I., Mangiarini L., Bates G. Identification of an HD patient with a (CAG)180 repeat expansion and the propagation of highly expanded CAG repeats in lambda phage. Hum. Genet. 99:1997;692-695.
10. Szybalski W., Kim S.C., Hasan N., Podhajska A.J. Class-IIS restriction enzymes - a review. Gene. 100:1991;13-26.
11. Takahashi N., Sasagawa N., Suzuki K., Ishiura S. Synthesis of long trinucleotide repeats in vitro. Neurosci. Lett. 262:1999;45-48.
12. Wells R.D., Warren S.T. Genetic Instabilities and Hereditary Neurological Diseases. 1998;Academic Press, San Diego, CA.