Deletion of Mint proteins decreases amyloid production in transgenic mouse models of Alzheimer's disease

Journal of Neuroscience

Volumn 28, Issue 53, 2008, Pages 14392-14400

  Ho, Angela ^a,c   Liu, Xinran ^a   Südhof, Thomas C ^a,b,d  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^b UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^c Boston University   (United States)

^d STANFORD UNIVERSITY   (United States)

Author keywords

amyloid; Alzheimer's disease; APP; Knock out; Mint; X11

Indexed keywords

AMYLOID BETA PROTEIN[1-40]; AMYLOID BETA PROTEIN[1-42]; BINDING PROTEIN; PROTEIN MINT1; PROTEIN MINT2; PROTEIN MINT3; UNCLASSIFIED DRUG;

ALZHEIMER DISEASE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; AGE FACTORS; ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN; AMYLOID BETA-PROTEIN PRECURSOR; AMYLOID PRECURSOR PROTEIN SECRETASES; ANIMALS; ANIMALS, NEWBORN; BRAIN; CELLS, CULTURED; CEREBRAL CORTEX; DISEASE MODELS, ANIMAL; ENZYME-LINKED IMMUNOSORBENT ASSAY; GENE DELETION; GENE EXPRESSION REGULATION; GREEN FLUORESCENT PROTEINS; HUMANS; MICE; MICE, TRANSGENIC; NERVE TISSUE PROTEINS; NEURONS; NUCLEAR LOCALIZATION SIGNALS; PEPTIDE FRAGMENTS; TRANSFECTION;

EID: 58149400148     PISSN: 02706474     EISSN: 02706474     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.2481-08.2008     Document Type: Article

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