The neuronal adaptor protein X11β reduces amyloid β-protein levels and amyloid plaque formation in the brains of transgenic mice

Journal of Biological Chemistry

Volumn 279, Issue 47, 2004, Pages 49099-49104

  Lee, Ju Hyun ^a   Lau, Kwok Fai ^a   Perkinton, Michael S ^a   Standen, Claire L ^a   Rogelj, Boris ^a   Falinska, Agnieszka ^a   McLoughlin, Declan M ^a   Miller, Christopher C J ^a  

^a KING'S COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BRAIN; CELLS; DEPOSITION; PATHOLOGY;

AMYLOID PRECURSORS; CLEAVAGE; PRECURSOR PROTEIN;

PROTEINS;

ADAPTOR PROTEIN; ADAPTOR PROTEIN X 11 BETA; AMYLOID BETA PROTEIN; AMYLOID PRECURSOR PROTEIN; BRAIN PROTEIN; UNCLASSIFIED DRUG;

ALZHEIMER DISEASE; AMYLOID NEUROPATHY; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; FEMALE; GENE OVEREXPRESSION; MALE; MOUSE; NERVE CELL; NEUROMODULATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; TRANSGENIC MOUSE;

ALZHEIMER DISEASE; AMYLOID; AMYLOID BETA-PROTEIN; ANIMALS; BLOTTING, NORTHERN; BRAIN; CADHERINS; CARRIER PROTEINS; CELL MEMBRANE; CLONING, MOLECULAR; CROSSES, GENETIC; FEMALE; HUMANS; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; MALE; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MUTATION; NERVE TISSUE PROTEINS; NEURONS; PROTEIN STRUCTURE, TERTIARY; RNA, MESSENGER;

ANIMALIA; MUS MUSCULUS;

EID: 10344227214     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M405602200     Document Type: Article

References (54)

1. Butz, S., Okamoto, M., and Sudhof, T. C. (1998) Cell 94, 773-782
2. Borg, J.-P., Straight, S. W., Kaech, S. M., De Taddéo-Borg, M., Kroon, D. E., Karnak, D., Turner, R. S., Kim, S. K., and Margolis, B. (1998) J. Biol. Chem. 273, 31633-31636
3. Lee, D.-S., Tomita, S., Kirino, Y., and Suzuki, T. (2000) J. Biol. Chem. 275, 23134-23138
4. Lau, K.-F., McLoughlin, D. M., Standen, C., and Miller, C. C. J. (2000) Mol. Cell. Neurosci. 16, 555-563
5. Biederer, T., Cao, X., Sudhof, T. C., and Liu, X. (2002) J. Neurosci. 22, 7340-7351
6. Biederer, T., and Südhof, T. C. (2000) J. Biol. Chem. 275, 39803-39806
7. Tomita, S., Fujita, T., Kirino, Y., and Suzuki, T. (2000) J. Biol. Chem. 275, 13056-13060
8. McLoughlin, D. M., and Miller, C. C. J. (1996) FEBS Lett. 397, 197-200
9. Tomita, S., Ozaki, T., Taru, H., Oguchi, S., Takeda, S., Yagi, Y., Sakiyama, S., Kirino, Y., and Suzuki, T. (1999) J. Biol. Chem. 274, 2243-2254
10. McLoughlin, D. M., Irving, N. G., Brownlees, J., Brion, J.-P., Leroy, K., and Miller, C. C. J. (1999) Eur. J. Neurosci. 11, 1988-1994
11. Borg, J.-P., Ooi, J., Levy, E., and Margolis, B. (1996) Mol. Cell. Biol. 16, 6229-6241
12. De Strooper, B., and Annaert, W. (2000) J. Cell Sci. 113, 1857-1870
13. Selkoe, D., and Kopan, R. (2003) Annu. Rev. Neurosci. 26, 565-597
14. De Strooper, B. (2003) Neuron 38, 9-12
15. King, G. D., and Turner, R. S. (2004) Exp. Neurol. 185, 208-219
16. Borg, J. P., Yang, Y. N., De Taddéo-Borg, M., Margolis, B., and Turner, R. S. (1998) J. Biol. Chem. 273, 14761-14766
17. Sastre, M., Turner, R. S., and Levy, E. (1998) J. Biol. Chem. 273, 22351-22357
18. Mueller, H. T., Borg, J. P., Margolis, B., and Turner, R. S. (2000) J. Biol. Chem. 275, 39302-39306
19. Lee, J. H., Lau, K. F., Perkinton, M. S., Standen, C. L., Shemilt, S. J., Mercken, L., Cooper, J. D., McLoughlin, D. M., and Miller, C. C. (2003) J. Biol. Chem. 278, 47025-47029
20. Busciglio, J., Gabuzda, D. H., Matsudaira, P., and Yankner, B. A. (1993) Proc. Natl. Acad. Sci. U. S. A. 90, 2092-2096
21. Turner, R. S., Suzuki, N., Chyung, A. S. C., Younkin, S. G., and Lee, V. M.-Y. (1996) J. Biol. Chem. 271, 8966-8970
22. Tienari, P. J., Ida, N., Ikonen, E., Simons, M., Weidemann, A., Multhaup, G., Masters, C. L., Dotti, C. G., and Beyreuther, K. (1997) Proc. Natl. Acad. Sci. U. S. A. 94, 4125-4130
23. Cook, D. G., Forman, M. S., Sung, J. C., Leight, S., Kolson, D. L., Iwatsubo, T., Lee, V. M.-Y., and Doms, R. W. (1997) Nat. Med. 3, 1021-1023
24. Araki, Y., Tomita, S., Yamaguchi, H., Miyagi, N., Sumioka, A., Kirino, Y., and Suzuki, T. (2003) J. Biol. Chem. 278, 49448-49458
25. Sumioka, A., Imoto, S., Martins, R. N., Kirino, Y., and Suzuki, T. (2003) Biochem. J. 374, 261-268
26. Standen, C. L., Brownlees, J., Grierson, A. J., Kesavapany, S., Lau, K. F., McLoughlin, D. M., and Miller, C. C. J. (2001) J. Neurochem. 76, 316-320
27. Ando, K, Iijima, K. I., Elliott, J. I., Kirino, Y., and Suzuki, T. (2001) J. Biol. Chem. 276, 40353-40361
28. Taru, H., and Suzuki, T. (2004) J. Biol. Chem. 279, 21628-21636
29. Hsiao, K, Chapman, P., Nilsen, S., Eckman, C., Harigaya, Y., Younkin, S., Yang, F. S., and Cole, G. (1996) Science 274, 99-102
30. Borchelt, D. R., Davis, J., Fischer, M., Lee, M. K., Slunt, H. H., Ratovitsky, T., Regard, J., Copeland, N. G., Jenkins, N. A., Sisodia, S. S., and Price, D. L. (1996) Genet. Anal. 13, 159-163
31. Kawarabayashi, T., Younkin, L. H., Saido, T. C., Shoji, M., Ashe, K. H., and Younkin, S. G. (2001) J. Neurosci. 21, 372-381
32. Lau, K. F., Hewlett, D. R., Kesavapany, S., Standen, C. L., Dingwall, C., McLoughlin, D. M., and Miller, C. C. J. (2002) Mol. Cell. Neurosci. 20, 13-20
33. Kurt, M. A., Davies, D. C., Kidd, M., Duff, K., Rolph, S. C., Jennings, K. H., and Howlett, D. R. (2001) Exp. Neurol. 171, 59-71
34. Jankowsky, J. L., Fadale, D. J., Anderson, J., Xu, G. M., Gonzales, V., Jenkins, N. A., Copeland, N. G., Lee, M. K., Younkin, L. H., Wagner, S. L., Younkin, S. G., and Borchelt, D. R. (2004) Hum. Mol. Genet. 13, 159-170
35. Borchelt, D. R., Thinakaran, G., Eckman, C. B., Lee, M. K., Davenport, F., Ratovitsky, T., Prada, C. M., Kim, G., Seekins, S., Yager, D., Slunt, H. H., Wang, R., Seeger, M., Levey, A. I., Gandy, S. E., Copeland, N. G., Jenkins, N. A., Price, D. L., Younkin, S. G., and Sisodia, S. S. (1996) Neuron 17, 1005-1013
36. Lesuisse, C., Xu, G., Anderson, J., Wong, M., Jankowsky, J., Holtz, G., Gonzalez, V., Wong, P. C., Price, D. L., Tang, F., Wagner, S., and Borchelt, D. R. (2001) Hum. Mol. Genet. 10, 2525-2537
37. Nakajima, Y., Okamoto, M., Nishimura, H., Obata, K., Kitano, H., Sugita, M., and Matsuyama, T. (2001) Mol. Brain Res. 92, 27-42
38. Borchelt, D. R., Ratovitski, T., Van Lare, J., Lee, M. K., Gonzales, V., Jenkins, N. A., Copeland, N. G., Price, D. L., and Sisodia, S. S. (1997) Neuron 19, 939-945
39. Holcomb, L., Gordon, M. N., McGowan, E., Yu, X., Benkovic, S., Jantzen, P., Wright, K., Saad, I., Mueller, R., Morgan, D., Sanders, S., Zehr, C., O'Campo, K., Hardy, J., Prada, C. M., Eckman, C., Younkin, S., Hsiao, K., and Duff, K. (1998) Nat. Med. 4, 97-100
40. Citron, M., Westaway, D., Xia, W. M., Carlson, G., Diehl, T., Levesque, G., Johnson-Wood, K., Lee, M., Seubert, P., Davis, A., Kholodenko, D., Motter, R., Sherrington, R., Perry, B., Yao, H., Strome, R., Lieberburg, I., Rommens, J., Kim, S., Schenk, D., Fraser, P., Hyslop, P. S., and Selkoe, D. J. (1997) Nat. Med. 3, 67-72
41. Dineley, K. T., Xia, X., Bui, D., Sweatt, J. D., and Zheng, H. (2002) J. Biol. Chem. 277, 22768-22780
42. Leissring, M. A., Farris, W., Chang, A. Y., Walsh, D. M., Wu, X., Sun, X., Frosch, M. P., and Selkoe, D. J. (2003) Neuron 40, 1087-1093
43. Bodendorf, U., Danner, S., Fischer, F., Stefani, M., Sturchler-Pierrat, C., Wiederhold, K. H., Staufenbiel, M., and Paganetti, P. (2002) J. Neurochem. 80, 799-806
44. Duff, K., and Rao, M. V. (2001) Curr. Opin. Neurol. 14, 441-447
45. Wong, P. C., Cai, H., Borchelt, D. R., and Price, D. L. (2002) Nat. Neurosci. 5, 633-639
46. Bressler, S. L., Gray, M. D., Sopher, B. L., Hu, Q. B., Hearn, M. G., Pham, D. G., Dinulos, M. B., Fukuchi, K. I., Sisodia, S. S., Miller, M. A., Disteche, C. M., and Martin, G. M. (1996) Hum. Mol. Genet. 5, 1589-1598
47. Zhang, Z., Lee, C.-H., Mandiyan, V., Borg, J.-P., Margolis, B., Schlessinger, J., and Kuriyan, J. (1997) EMBO J. 16, 6141-6150
48. Trommsdorff, M., Borg, J.-P., Margolis, B., and Herz, J. (1998) J. Biol. Chem. 273, 33556-33560
49. Tanahashi, H., and Tabira, T. (1999) Biochem. Biophys. Res. Commun. 255, 663-667
50. Okamoto, M., and Sudhof, T. C. (1997) J. Biol. Chem. 272, 31459-31464
51. Okamoto, M., and Sudhof, T. C. (1998) Eur. J. Cell Biol. 77, 161-165
52. Borg, J. P., Lopez-Figueroa, M. O., De Taddéo-Borg, M., Kroon, D. E., Turner, R. S., Watson, S. J., and Margolis, B. (1999) J. Neurosci. 19, 1307-1316
53. Hartmann, T., Bieger, S. C., Brühl, B., Tienari, P. J., Ida, N., Allsop, D., Roberts, G. W., Masters, C. L., Dotti, C. G., Unsicker, K., and Beyreuther, K. (1997) Nat. Med. 3, 1016-1020
54. King, G. D., Cherian, K., and Turner, R. S. (2004) J. Neurochem. 88, 971-982