-
1
-
-
0026340976
-
Pathology of roots, spinal cord and brainstem in syringomyelia-like syndrome of Tangier disease
-
J.C. Antoine, M. Tommasi, S. Boucheron, P. Convers, B. Laurent and D. Michel, Pathology of roots, spinal cord and brainstem in syringomyelia-like syndrome of Tangier disease, J Neurol Sci 106 (1991), 179-185.
-
(1991)
J Neurol Sci
, vol.106
, pp. 179-185
-
-
Antoine, J.C.1
Tommasi, M.2
Boucheron, S.3
Convers, P.4
Laurent, B.5
Michel, D.6
-
2
-
-
43249094747
-
Statins, incident Alzheimer disease, change in cognitive function, and neuropathology
-
Z. Arvanitakis, J.A. Schneider, R.S. Wilson, J.L. Bienias, J.F. Kelly, D.A. Evans and D.A. Bennett, Statins, incident Alzheimer disease, change in cognitive function, and neuropathology, Neurology 70 (2008), 1795-1802.
-
(2008)
Neurology
, vol.70
, pp. 1795-1802
-
-
Arvanitakis, Z.1
Schneider, J.A.2
Wilson, R.S.3
Bienias, J.L.4
Kelly, J.F.5
Evans, D.A.6
Bennett, D.A.7
-
3
-
-
0035145398
-
Inclusion-body myositis: Newest concepts of pathogenesis and relation to aging and Alzheimer disease
-
V. Askanas and W.K. Engel, Inclusion-body myositis: newest concepts of pathogenesis and relation to aging and Alzheimer disease, J Neuropathol Exp Neurol 60 (2001), 1-14.
-
(2001)
J Neuropathol Exp Neurol
, vol.60
, pp. 1-14
-
-
Askanas, V.1
Engel, W.K.2
-
4
-
-
0037283629
-
The role of intracellular cholesterol on the processing of the beta-amyloid precursor protein
-
B.M. Austen, C. Sidera, C. Liu and E. Frears, The role of intracellular cholesterol on the processing of the beta-amyloid precursor protein, J Nutr Health Aging 7 (2003), 31-36.
-
(2003)
J Nutr Health Aging
, vol.7
, pp. 31-36
-
-
Austen, B.M.1
Sidera, C.2
Liu, C.3
Frears, E.4
-
5
-
-
0346770038
-
Age-related myelin breakdown: A developmental model of cognitive decline and Alzheimer's disease
-
G. Bartzokis, Age-related myelin breakdown: a developmental model of cognitive decline and Alzheimer's disease, Neurobiol Aging 25 (2004), 5-18.
-
(2004)
Neurobiol Aging
, vol.25
, pp. 5-18
-
-
Bartzokis, G.1
-
6
-
-
32944473282
-
Nuclear receptors in lipid metabolism: Targeting the heart of dyslipidemia
-
S.W. Beaven and P. Tontonoz, Nuclear receptors in lipid metabolism: targeting the heart of dyslipidemia, Ann Rev Med 57 (2006), 313-329.
-
(2006)
Ann Rev Med
, vol.57
, pp. 313-329
-
-
Beaven, S.W.1
Tontonoz, P.2
-
7
-
-
2442557294
-
Brain cholesterol: Long secret life behind a barrier
-
I. Bjorkhem and S. Meaney, Brain cholesterol: long secret life behind a barrier, Arterioscler Thromb Vasc Biol 24 (2004), 806-815.
-
(2004)
Arterioscler Thromb Vasc Biol
, vol.24
, pp. 806-815
-
-
Bjorkhem, I.1
Meaney, S.2
-
8
-
-
0035985702
-
Oxysterols in human circulation: Which role do they have?
-
I. Bjorkhem, S. Meaney and U. Diczfalusy, Oxysterols in human circulation: which role do they have? Curr Opin Lipidol 13 (2002), 247-253.
-
(2002)
Curr Opin Lipidol
, vol.13
, pp. 247-253
-
-
Bjorkhem, I.1
Meaney, S.2
Diczfalusy, U.3
-
9
-
-
0030896414
-
Isolation and culture of adult rat hippocampal neurons
-
G.J. Brewer, Isolation and culture of adult rat hippocampal neurons, J Neurosci Meth 71 (1997), 143-155.
-
(1997)
J Neurosci Meth
, vol.71
, pp. 143-155
-
-
Brewer, G.J.1
-
10
-
-
0032890337
-
Oxysterols and atherosclerosis
-
A.J. Brown and W. Jessup, Oxysterols and atherosclerosis, Atherosclerosis 142 (1999), 1-28.
-
(1999)
Atherosclerosis
, vol.142
, pp. 1-28
-
-
Brown, A.J.1
Jessup, W.2
-
11
-
-
4544255297
-
Differential expression of cholesterol hydroxylases in Alzheimer's disease
-
J. Brown, III, C. Theisler, S. Silberman, D. Magnuson, N. Gottardi-Littell, J.M. Lee, D. Yager, J. Crowley, K. Sambamurti, M.M. Rahman, A.B. Reiss, C.B. Eckman and B. Wolozin, Differential expression of cholesterol hydroxylases in Alzheimer's disease, J Biol Chem 279 (2004), 34674-34681.
-
(2004)
J Biol Chem
, vol.279
, pp. 34674-34681
-
-
Brown III, J.1
Theisler, C.2
Silberman, S.3
Magnuson, D.4
Gottardi-Littell, N.5
Lee, J.M.6
Yager, D.7
Crowley, J.8
Sambamurti, K.9
Rahman, M.M.10
Reiss, A.B.11
Eckman, C.B.12
Wolozin, B.13
-
12
-
-
0037474140
-
Co-localization of cholesterol, apolipoprotein E and fibrillar Abeta in amyloid plaques
-
M.P. Burns, W.J. Noble, V. Olm, K. Gaynor, E. Casey, J. LaFrancois, L.Wang and K. Duff, Co-localization of cholesterol, apolipoprotein E and fibrillar Abeta in amyloid plaques, Brain Res Mol Brain Res 110 (2003), 119-125.
-
(2003)
Brain Res Mol Brain Res
, vol.110
, pp. 119-125
-
-
Burns, M.P.1
Noble, W.J.2
Olm, V.3
Gaynor, K.4
Casey, E.5
LaFrancois, J.6
Wang, L.7
Duff, K.8
-
13
-
-
44849101912
-
Effects of simvastatin on cerebrospinal fluid biomarkers and cognition in middle-aged adults at risk for Alzheimer's disease
-
C.M. Carlsson, C.E. Gleason, T.M. Hess, K.A. Moreland, H.M. Blazel, R.L. Koscik, N.T. Schreiber, S.C. Johnson, C.S. Atwood, L. Puglielli, B.P. Hermann, P.E. McBride, J.H. Stein, M.A. Sager and S. Asthana, Effects of simvastatin on cerebrospinal fluid biomarkers and cognition in middle-aged adults at risk for Alzheimer's disease, J Alzheimers Dis 13 (2008), 187-197.
-
(2008)
J Alzheimers Dis
, vol.13
, pp. 187-197
-
-
Carlsson, C.M.1
Gleason, C.E.2
Hess, T.M.3
Moreland, K.A.4
Blazel, H.M.5
Koscik, R.L.6
Schreiber, N.T.7
Johnson, S.C.8
Atwood, C.S.9
Puglielli, L.10
Hermann, B.P.11
McBride, P.E.12
Stein, J.H.13
Sager, M.A.14
Asthana, S.15
-
14
-
-
42649109113
-
Caffeine blocks disruption of blood brain barrier in a rabbit model of Alzheimer's disease
-
X.Chen, J.W. Gawryluk, J.F. Wagener, O. Ghribi and J.D. Geiger, Caffeine blocks disruption of blood brain barrier in a rabbit model of Alzheimer's disease, J Neuroinflammation 5 (2008), 12.
-
(2008)
J Neuroinflammation
, vol.5
, pp. 12
-
-
Chen, X.1
Gawryluk, J.W.2
Wagener, J.F.3
Ghribi, O.4
Geiger, J.D.5
-
15
-
-
40449121222
-
Rabbits fed cholesterol-enriched diets exhibit pathological features of inclusion body myositis
-
X. Chen, O. Ghribi and J.D. Geiger, Rabbits fed cholesterol-enriched diets exhibit pathological features of inclusion body myositis, Am J Physiol Regul Integr Comp Physiol 294 (2008), 829-835.
-
(2008)
Am J Physiol Regul Integr Comp Physiol
, vol.294
, pp. 829-835
-
-
Chen, X.1
Ghribi, O.2
Geiger, J.D.3
-
16
-
-
33748072442
-
NO synthase 2 (NOS2) deletion promotes multiple pathologies in a mouse model of Alzheimer's disease
-
C.A. Colton, M.P. Vitek, D.A. Wink, Q. Xu, V. Cantillana, M.L. Previti, W.E. Van Nostrand, J.B. Weinberg and H. Dawson, NO synthase 2 (NOS2) deletion promotes multiple pathologies in a mouse model of Alzheimer's disease, Proc Natl Acad Sci USA 103 (2006), 12867-12872.
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 12867-12872
-
-
Colton, C.A.1
Vitek, M.P.2
Wink, D.A.3
Xu, Q.4
Cantillana, V.5
Previti, M.L.6
Van Nostrand, W.E.7
Weinberg, J.B.8
Dawson, H.9
-
17
-
-
0027194791
-
Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families
-
E.H. Corder, A.M. Saunders, W.J. Strittmatter, D.E. Schmechel, P.C. Gaskell, G.W. Small, A.D. Roses, J.L. Haines and M.A. Pericak-Vance, Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families, Science 261 (1993), 921-923.
-
(1993)
Science
, vol.261
, pp. 921-923
-
-
Corder, E.H.1
Saunders, A.M.2
Strittmatter, W.J.3
Schmechel, D.E.4
Gaskell, P.C.5
Small, G.W.6
Roses, A.D.7
Haines, J.L.8
Pericak-Vance, M.A.9
-
18
-
-
0141482022
-
Exclusively targeting beta-secretase to lipid rafts by GPI-anchor addition up-regulates beta-site processing of the amyloid precursor protein
-
J.M. Cordy, I. Hussain, C. Dingwall, N.M. Hooper and A.J. Turner, Exclusively targeting beta-secretase to lipid rafts by GPI-anchor addition up-regulates beta-site processing of the amyloid precursor protein, Proc Natl Acad Sci USA 100 (2003), 11735-11740.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 11735-11740
-
-
Cordy, J.M.1
Hussain, I.2
Dingwall, C.3
Hooper, N.M.4
Turner, A.J.5
-
19
-
-
0038415954
-
Neuroprotection by caffeine and adenosine A2A receptor blockade of beta-amyloid neurotoxicity
-
O.P. Dall'Igna, L.O. Porciuncula, D.O. Souza, R.A. Cunha and D.R. Lara, Neuroprotection by caffeine and adenosine A2A receptor blockade of beta-amyloid neurotoxicity, Br J Pharmacol 138 (2003), 1207-1209.
-
(2003)
Br J Pharmacol
, vol.138
, pp. 1207-1209
-
-
Dall'Igna, O.P.1
Porciuncula, L.O.2
Souza, D.O.3
Cunha, R.A.4
Lara, D.R.5
-
20
-
-
4043061467
-
LRP/amyloid beta-peptide interaction mediates differential brain efflux of Abeta isoforms
-
R. Deane, Z.Wu, A. Sagare, J. Davis, Y.S. Du, K. Hamm, F. Xu, M. Parisi, B. LaRue, H.W. Hu, P. Spijkers, H. Guo, X. Song, P.J. Lenting, W.E. Van Nostrand and B.V. Zlokovic, LRP/amyloid beta-peptide interaction mediates differential brain efflux of Abeta isoforms, Neuron 43 (2004), 333-344.
-
(2004)
Neuron
, vol.43
, pp. 333-344
-
-
Deane, R.1
Wu, Z.2
Sagare, A.3
Davis, J.4
Du, Y.S.5
Hamm, K.6
Xu, F.7
Parisi, M.8
LaRue, B.9
Hu, H.W.10
Spijkers, P.11
Guo, H.12
Song, X.13
Lenting, P.J.14
Van Nostrand, W.E.15
Zlokovic, B.V.16
-
21
-
-
7644225312
-
RAGE (yin) versus LRP (yang) balance regulates alzheimer amyloid beta-peptide clearance through transport across the blood-brain barrier
-
R. Deane, Z.Wu and B.V. Zlokovic, RAGE (yin) versus LRP (yang) balance regulates alzheimer amyloid beta-peptide clearance through transport across the blood-brain barrier, Stroke 35 (2004), 2628-2631.
-
(2004)
Stroke
, vol.35
, pp. 2628-2631
-
-
Deane, R.1
Wu, Z.2
Zlokovic, B.V.3
-
22
-
-
0034925263
-
Tangle-bearing neurons contain more free cholesterol than adjacent tangle-free neurons
-
R. Distl, V. Meske and T.G. Ohm, Tangle-bearing neurons contain more free cholesterol than adjacent tangle-free neurons, Acta Neuropathol (Berl) 101 (2001), 547-554.
-
(2001)
Acta Neuropathol (Berl)
, vol.101
, pp. 547-554
-
-
Distl, R.1
Meske, V.2
Ohm, T.G.3
-
23
-
-
0023764870
-
Familial hypercholesterolemia and apolipoprotein E4
-
M. Eto, K. Watanabe, N. Chonan and K. Ishii, Familial hypercholesterolemia and apolipoprotein E4, Atherosclerosis 72 (1988), 123-128.
-
(1988)
Atherosclerosis
, vol.72
, pp. 123-128
-
-
Eto, M.1
Watanabe, K.2
Chonan, N.3
Ishii, K.4
-
24
-
-
0001504829
-
Simvastatin strongly reduces levels of Alzheimer's disease beta -amyloid peptides Abeta 42 and Abeta 40 in vitro and in vivo
-
K. Fassbender, M. Simons, C. Bergmann, M. Stroick, D. Lutjohann, P. Keller, H. Runz, S. Kuhl, T. Bertsch, K. von Bergmann, M. Hennerici, K. Beyreuther and T. Hartmann, Simvastatin strongly reduces levels of Alzheimer's disease beta -amyloid peptides Abeta 42 and Abeta 40 in vitro and in vivo, Proc Natl Acad Sci USA 98 (2001), 5856-5861.
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 5856-5861
-
-
Fassbender, K.1
Simons, M.2
Bergmann, C.3
Stroick, M.4
Lutjohann, D.5
Keller, P.6
Runz, H.7
Kuhl, S.8
Bertsch, T.9
von Bergmann, K.10
Hennerici, M.11
Beyreuther, K.12
Hartmann, T.13
-
25
-
-
0033519601
-
The role of cholesterol in the biosynthesis of betaamyloid
-
E.R. Frears, D.J. Stephens, C.E.Walters, H. Davies and B.M. Austen, The role of cholesterol in the biosynthesis of betaamyloid, Neuroreport 10 (1999), 1699-1705.
-
(1999)
Neuroreport
, vol.10
, pp. 1699-1705
-
-
Frears, E.R.1
Stephens, D.J.2
Walters, C.E.3
Davies, H.4
Austen, B.M.5
-
26
-
-
0035914330
-
27-hydroxycholesterol is an endogenous ligand for liver X receptor in cholesterolloaded cells
-
X. Fu, J.G. Menke, Y. Chen, G. Zhou, K.L. MacNaul, S.D. Wright, C.P. Sparrow and E.G. Lund, 27-hydroxycholesterol is an endogenous ligand for liver X receptor in cholesterolloaded cells, J Biol Chem 276 (2001), 38378-38387.
-
(2001)
J Biol Chem
, vol.276
, pp. 38378-38387
-
-
Fu, X.1
Menke, J.G.2
Chen, Y.3
Zhou, G.4
MacNaul, K.L.5
Wright, S.D.6
Sparrow, C.P.7
Lund, E.G.8
-
27
-
-
0034214328
-
Cholesterol decreases secretion of the secreted form of amyloid precursor protein by interfering with glycosylation in the protein secretory pathway
-
J.L. Galbete, T.R. Martin, E. Peressini, P. Modena, R. Bianchi and G. Forloni, Cholesterol decreases secretion of the secreted form of amyloid precursor protein by interfering with glycosylation in the protein secretory pathway, Biochem J 348 (2000), 307-313.
-
(2000)
Biochem J
, vol.348
, pp. 307-313
-
-
Galbete, J.L.1
Martin, T.R.2
Peressini, E.3
Modena, P.4
Bianchi, R.5
Forloni, G.6
-
28
-
-
0041689948
-
Caspase cleavage of tau: Linking amyloid and neurofibrillary tangles in Alzheimer's disease
-
T.C. Gamblin, F. Chen, A. Zambrano, A. Abraha, S. Lagalwar, A.L. Guillozet, M. Lu, Y. Fu, F. Garcia-Sierra, N. LaPointe, R. Miller, R.W. Berry, L.I. Binder and V.L. Cryns, Caspase cleavage of tau: linking amyloid and neurofibrillary tangles in Alzheimer's disease, Proc Natl Acad Sci USA 100 (2003), 10032-10037.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 10032-10037
-
-
Gamblin, T.C.1
Chen, F.2
Zambrano, A.3
Abraha, A.4
Lagalwar, S.5
Guillozet, A.L.6
Lu, M.7
Fu, Y.8
Garcia-Sierra, F.9
LaPointe, N.10
Miller, R.11
Berry, R.W.12
Binder, L.I.13
Cryns, V.L.14
-
29
-
-
33846953912
-
Preservation of the blood brain barrier integrity may underlie neuroprotective effects of statins in Alzheimer's disease
-
O. Ghribi, Preservation of the blood brain barrier integrity may underlie neuroprotective effects of statins in Alzheimer's disease, J Alzheimers Dis 10 (2006), 407-408.
-
(2006)
J Alzheimers Dis
, vol.10
, pp. 407-408
-
-
Ghribi, O.1
-
30
-
-
33749161414
-
Deposition of iron and beta-amyloid plaques is associated with cortical cellular damage in rabbits fed with long-term cholesterol-enriched diets
-
O. Ghribi, M.Y. Golovko, B. Larsen, M. Schrag and E.J. Murphy, Deposition of iron and beta-amyloid plaques is associated with cortical cellular damage in rabbits fed with long-term cholesterol-enriched diets, J Neurochem 99 (2006), 438-449.
-
(2006)
J Neurochem
, vol.99
, pp. 438-449
-
-
Ghribi, O.1
Golovko, M.Y.2
Larsen, B.3
Schrag, M.4
Murphy, E.J.5
-
31
-
-
0037443604
-
Lithium inhibits Abeta-induced stress in endoplasmic reticulum of rabbit hippocampus but does not prevent oxidative damage and tau phosphorylation
-
O. Ghribi, M.M. Herman and J. Savory, Lithium inhibits Abeta-induced stress in endoplasmic reticulum of rabbit hippocampus but does not prevent oxidative damage and tau phosphorylation, J Neurosci Res 71 (2003), 853-862.
-
(2003)
J Neurosci Res
, vol.71
, pp. 853-862
-
-
Ghribi, O.1
Herman, M.M.2
Savory, J.3
-
32
-
-
33746299216
-
High cholesterol content in neurons increases BACE, betaamyloid, and phosphorylated tau levels in rabbit hippocampus
-
O. Ghribi, B. Larsen, M. Schrag and M.M. Herman, High cholesterol content in neurons increases BACE, betaamyloid, and phosphorylated tau levels in rabbit hippocampus, Exp Neurol 200 (2006), 460-467.
-
(2006)
Exp Neurol
, vol.200
, pp. 460-467
-
-
Ghribi, O.1
Larsen, B.2
Schrag, M.3
Herman, M.M.4
-
33
-
-
0242475154
-
Abeta(1-42)-induced JNK and ERK activation in rabbit hippocampus is differentially regulated by lithium but is not involved in the phosphorylation of tau
-
O. Ghribi, P. Prammonjago, M.M. Herman, N.K. Spaulding and J. Savory, Abeta(1-42)-induced JNK and ERK activation in rabbit hippocampus is differentially regulated by lithium but is not involved in the phosphorylation of tau, Brain Res Mol Brain Res 119 (2003), 201-206.
-
(2003)
Brain Res Mol Brain Res
, vol.119
, pp. 201-206
-
-
Ghribi, O.1
Prammonjago, P.2
Herman, M.M.3
Spaulding, N.K.4
Savory, J.5
-
34
-
-
0027973639
-
Alzheimer's disease. Risky apolipoprotein in brain
-
M. Goedert, W.J. Strittmatter and A.D. Roses, Alzheimer's disease. Risky apolipoprotein in brain, Nature 372 (1994), 45-46.
-
(1994)
Nature
, vol.372
, pp. 45-46
-
-
Goedert, M.1
Strittmatter, W.J.2
Roses, A.D.3
-
35
-
-
0035943436
-
Formation of neurofibrillary tangles in P301l tau transgenic mice induced by Abeta 42 fibrils
-
J. Gotz, F. Chen, D.J. van and R.M. Nitsch, Formation of neurofibrillary tangles in P301l tau transgenic mice induced by Abeta 42 fibrils, Science 293 (2001), 1491-1495.
-
(2001)
Science
, vol.293
, pp. 1491-1495
-
-
Gotz, J.1
Chen, F.2
van, D.J.3
Nitsch, R.M.4
-
36
-
-
0028179001
-
Secreted beta-amyloid precursor protein stimulates mitogen-activated protein kinase and enhances tau phosphorylation
-
S.M. Greenberg, E.H. Koo, D.J. Selkoe, W.Q. Qiu and K.S. Kosik, Secreted beta-amyloid precursor protein stimulates mitogen-activated protein kinase and enhances tau phosphorylation, Proc Natl Acad Sci USA 91 (1994), 7104-7108.
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 7104-7108
-
-
Greenberg, S.M.1
Koo, E.H.2
Selkoe, D.J.3
Qiu, W.Q.4
Kosik, K.S.5
-
37
-
-
0842303768
-
Changes in the levels of cerebral and extracerebral sterols in the brain of patients with Alzheimer's disease
-
M. Heverin, N. Bogdanovic, D. Lutjohann, T. Bayer, I. Pikuleva, L. Bretillon, U. Diczfalusy, B. Winblad and I. Bjorkhem, Changes in the levels of cerebral and extracerebral sterols in the brain of patients with Alzheimer's disease, J Lipid Res 45 (2004), 186-193.
-
(2004)
J Lipid Res
, vol.45
, pp. 186-193
-
-
Heverin, M.1
Bogdanovic, N.2
Lutjohann, D.3
Bayer, T.4
Pikuleva, I.5
Bretillon, L.6
Diczfalusy, U.7
Winblad, B.8
Bjorkhem, I.9
-
38
-
-
23744498856
-
Crossing the barrier: Net flux of 27-hydroxycholesterol into the human brain
-
M. Heverin, S. Meaney, D. Lutjohann, U. Diczfalusy, J. Wahren and I. Bjorkhem, Crossing the barrier: Net flux of 27-hydroxycholesterol into the human brain, J Lipid Res 46 (2005), 1047-1052.
-
(2005)
J Lipid Res
, vol.46
, pp. 1047-1052
-
-
Heverin, M.1
Meaney, S.2
Lutjohann, D.3
Diczfalusy, U.4
Wahren, J.5
Bjorkhem, I.6
-
39
-
-
30044441879
-
The absence of ABCA1 decreases soluble ApoE levels but does not diminish amyloid deposition in two murine models of Alzheimer disease
-
V. Hirsch-Reinshagen, L.F. Maia, B.L. Burgess, J.F. Blain, K.E. Naus, S.A. McIsaac, P.F. Parkinson, J.Y. Chan, G.H. Tansley, M.R. Hayden, J. Poirier, N.W. van and C.L. Wellington, The absence of ABCA1 decreases soluble ApoE levels but does not diminish amyloid deposition in two murine models of Alzheimer disease, J Biol Chem 280 (2005), 43243-43256.
-
(2005)
J Biol Chem
, vol.280
, pp. 43243-43256
-
-
Hirsch-Reinshagen, V.1
Maia, L.F.2
Burgess, B.L.3
Blain, J.F.4
Naus, K.E.5
McIsaac, S.A.6
Parkinson, P.F.7
Chan, J.Y.8
Tansley, G.H.9
Hayden, M.R.10
Poirier, J.11
van, N.W.12
Wellington, C.L.13
-
40
-
-
0036260892
-
Increased expression of the amyloid precursor beta-secretase in Alzheimer's disease
-
R.M. Holsinger, C.A. McLean, K. Beyreuther, C.L. Masters and G. Evin, Increased expression of the amyloid precursor beta-secretase in Alzheimer's disease, Ann Neurol 51 (2002), 783-786.
-
(2002)
Ann Neurol
, vol.51
, pp. 783-786
-
-
Holsinger, R.M.1
McLean, C.A.2
Beyreuther, K.3
Masters, C.L.4
Evin, G.5
-
41
-
-
0036085783
-
Cholesterol, hydroxycholesterols, and bile acids
-
N.B. Javitt, Cholesterol, hydroxycholesterols, and bile acids, Biochem Biophys Res Commun 292 (2002), 1147-1153.
-
(2002)
Biochem Biophys Res Commun
, vol.292
, pp. 1147-1153
-
-
Javitt, N.B.1
-
42
-
-
44649197748
-
ApoE promotes the proteolytic degradation of Abeta
-
Q. Jiang, C.Y. Lee, S. Mandrekar, B. Wilkinson, P. Cramer, N. Zelcer, K. Mann, B. Lamb, T.M. Willson, J.L. Collins, J.C. Richardson, J.D. Smith, T.A. Comery, D. Riddell, D.M. Holtzman, P. Tontonoz and G.E. Landreth, ApoE promotes the proteolytic degradation of Abeta, Neuron 58 (2008), 681-693.
-
(2008)
Neuron
, vol.58
, pp. 681-693
-
-
Jiang, Q.1
Lee, C.Y.2
Mandrekar, S.3
Wilkinson, B.4
Cramer, P.5
Zelcer, N.6
Mann, K.7
Lamb, B.8
Willson, T.M.9
Collins, J.L.10
Richardson, J.C.11
Smith, J.D.12
Comery, T.A.13
Riddell, D.14
Holtzman, D.M.15
Tontonoz, P.16
Landreth, G.E.17
-
43
-
-
0034638746
-
Statins and the risk of dementia
-
H. Jick, G.L. Zornberg, S.S. Jick, S. Seshadri and D.A. Drachman, Statins and the risk of dementia, Lancet 356 (2000), 1627-1631.
-
(2000)
Lancet
, vol.356
, pp. 1627-1631
-
-
Jick, H.1
Zornberg, G.L.2
Jick, S.S.3
Seshadri, S.4
Drachman, D.A.5
-
44
-
-
58849154028
-
Impact of 27-Hydroxycholesterol on Amyloid-β Peptide Production and ATP-Binding Cassette Transporter Expression in Primary Human Neurons
-
in press
-
W.S. Kim, S.L. Chan, A.F. Hill, G.J. Guillemin and B. Garner, Impact of 27-Hydroxycholesterol on Amyloid-β Peptide Production and ATP-Binding Cassette Transporter Expression in Primary Human Neurons, J Alzheimers Dis 16 (2009), in press.
-
(2009)
J Alzheimers Dis
, vol.16
-
-
Kim, W.S.1
Chan, S.L.2
Hill, A.F.3
Guillemin, G.J.4
Garner, B.5
-
45
-
-
33745054649
-
Quantitation of ATP-binding cassette subfamily-A transporter gene expression in primary human brain cells
-
W.S. Kim, G.J. Guillemin, E.N. Glaros, C.K. Lim and B. Garner, Quantitation of ATP-binding cassette subfamily-A transporter gene expression in primary human brain cells, Neuroreport 17 (2006), 891-896.
-
(2006)
Neuroreport
, vol.17
, pp. 891-896
-
-
Kim, W.S.1
Guillemin, G.J.2
Glaros, E.N.3
Lim, C.K.4
Garner, B.5
-
46
-
-
39749104095
-
Role of ATP-binding cassette transporters in brain lipid transport and neurological disease
-
W.S. Kim, C.S. Weickert and B. Garner, Role of ATP-binding cassette transporters in brain lipid transport and neurological disease, J Neurochem 104 (2008), 1145-1166.
-
(2008)
J Neurochem
, vol.104
, pp. 1145-1166
-
-
Kim, W.S.1
Weickert, C.S.2
Garner, B.3
-
47
-
-
0035954333
-
Midlife vascular risk factors and late-life mild cognitive impairment: A population-based study
-
M. Kivipelto, E.L. Helkala, T. Hanninen, M.P. Laakso, M. Hallikainen, K. Alhainen, H. Soininen, J. Tuomilehto and A. Nissinen, Midlife vascular risk factors and late-life mild cognitive impairment: A population-based study, Neurology 56 (2001), 1683-1689.
-
(2001)
Neurology
, vol.56
, pp. 1683-1689
-
-
Kivipelto, M.1
Helkala, E.L.2
Hanninen, T.3
Laakso, M.P.4
Hallikainen, M.5
Alhainen, K.6
Soininen, H.7
Tuomilehto, J.8
Nissinen, A.9
-
48
-
-
30044438463
-
Lack of ABCA1 considerably decreases brain ApoE level and increases amyloid deposition in APP23 mice
-
R. Koldamova, M. Staufenbiel and I. Lefterov, Lack of ABCA1 considerably decreases brain ApoE level and increases amyloid deposition in APP23 mice, J Biol Chem 280 (2005), 43224-43235.
-
(2005)
J Biol Chem
, vol.280
, pp. 43224-43235
-
-
Koldamova, R.1
Staufenbiel, M.2
Lefterov, I.3
-
49
-
-
0037969631
-
22R-hydroxycholesterol and 9-cis-retinoic acid induce ATP-binding cassette transporter A1 expression and cholesterol efflux in brain cells and decrease amyloid beta secretion
-
R. Koldamova, I.M. Lefterov, M.D. Ikonomovic, J. Skoko, P.I. Lefterov, B.A. Isanski, S.T. DeKosky and J.S. Lazo, 22R-hydroxycholesterol and 9-cis-retinoic acid induce ATP-binding cassette transporter A1 expression and cholesterol efflux in brain cells and decrease amyloid beta secretion, J Biol Chem 278 (2003), 13244-13256.
-
(2003)
J Biol Chem
, vol.278
, pp. 13244-13256
-
-
Koldamova, R.1
Lefterov, I.M.2
Ikonomovic, M.D.3
Skoko, J.4
Lefterov, P.I.5
Isanski, B.A.6
DeKosky, S.T.7
Lazo, J.S.8
-
50
-
-
0034533147
-
Statins as a newly recognized type of immunomodulator
-
B. Kwak, F. Mulhaupt, S. Myit and F. Mach, Statins as a newly recognized type of immunomodulator, Nat Med 6 (2000), 1399-1402.
-
(2000)
Nat Med
, vol.6
, pp. 1399-1402
-
-
Kwak, B.1
Mulhaupt, F.2
Myit, S.3
Mach, F.4
-
51
-
-
0033384957
-
Regulation of endoplasmic reticulum cholesterol by plasma membrane cholesterol
-
Y. Lange, J.Ye, M. Rigney and T.L. Steck, Regulation of endoplasmic reticulum cholesterol by plasma membrane cholesterol, J Lipid Res 40 (1999), 2264-2270.
-
(1999)
J Lipid Res
, vol.40
, pp. 2264-2270
-
-
Lange, Y.1
Ye, J.2
Rigney, M.3
Steck, T.L.4
-
52
-
-
28244461327
-
Regulation of hippocampal cholesterol metabolism by apoE and environmental stimulation
-
O. Levi, D. Lutjohann, A. Devir, B.K. von, T. Hartmann and D.M. Michaelson, Regulation of hippocampal cholesterol metabolism by apoE and environmental stimulation, J Neurochem 95 (2005), 987-997.
-
(2005)
J Neurochem
, vol.95
, pp. 987-997
-
-
Levi, O.1
Lutjohann, D.2
Devir, A.3
von, B.K.4
Hartmann, T.5
Michaelson, D.M.6
-
53
-
-
17944382037
-
Enhanced neurofibrillary degeneration in transgenic mice expressing mutant tau and APP
-
J. Lewis, D.W. Dickson, W.L. Lin, L. Chisholm, A. Corral, G. Jones, S.H. Yen, N. Sahara, L. Skipper, D. Yager, C. Eckman, J. Hardy, M. Hutton and E. McGowan, Enhanced neurofibrillary degeneration in transgenic mice expressing mutant tau and APP, Science 293 (2001), 1487-1491.
-
(2001)
Science
, vol.293
, pp. 1487-1491
-
-
Lewis, J.1
Dickson, D.W.2
Lin, W.L.3
Chisholm, L.4
Corral, A.5
Jones, G.6
Yen, S.H.7
Sahara, N.8
Skipper, L.9
Yager, D.10
Eckman, C.11
Hardy, J.12
Hutton, M.13
McGowan, E.14
-
54
-
-
0942265972
-
Amyloid-beta-induced toxicity of primary neurons is dependent upon differentiation-associated increases in tau and cyclin-dependent kinase 5 expression
-
T. Liu, G. Perry, H.W. Chan, G. Verdile, R.N. Martins, M.A. Smith and C.S. Atwood, Amyloid-beta-induced toxicity of primary neurons is dependent upon differentiation-associated increases in tau and cyclin-dependent kinase 5 expression, J Neurochem 88 (2004), 554-563.
-
(2004)
J Neurochem
, vol.88
, pp. 554-563
-
-
Liu, T.1
Perry, G.2
Chan, H.W.3
Verdile, G.4
Martins, R.N.5
Smith, M.A.6
Atwood, C.S.7
-
55
-
-
0033594903
-
cDNA cloning of cholesterol 24-hydroxylase, a mediator of cholesterol homeostasis in the brain
-
E.G. Lund, J.M. Guileyardo and D.W. Russell, cDNA cloning of cholesterol 24-hydroxylase, a mediator of cholesterol homeostasis in the brain, Proc Natl Acad Sci USA 96 (1999), 7238-7243.
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 7238-7243
-
-
Lund, E.G.1
Guileyardo, J.M.2
Russell, D.W.3
-
56
-
-
0029835410
-
Cholesterol homeostasis in human brain: Evidence for an age-dependent flux of 24S-hydroxycholesterol from the brain into the circulation
-
D. Lutjohann, O. Breuer, G. Ahlborg, I. Nennesmo, A. Siden, U. Diczfalusy and I. Bjorkhem, Cholesterol homeostasis in human brain: evidence for an age-dependent flux of 24S-hydroxycholesterol from the brain into the circulation, Proc Natl Acad Sci USA 93 (1996), 9799-9804.
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 9799-9804
-
-
Lutjohann, D.1
Breuer, O.2
Ahlborg, G.3
Nennesmo, I.4
Siden, A.5
Diczfalusy, U.6
Bjorkhem, I.7
-
57
-
-
0343775806
-
Plasma 24S-hydroxycholesterol (cerebrosterol) is increased in Alzheimer and vascular demented patients
-
D. Lutjohann, A. Papassotiropoulos, I. Bjorkhem, S. Locatelli, M. Bagli, R. D. Oehring, U. Schlegel, F. Jessen, M. L. Rao, K. von Bergmann and R. Heun, Plasma 24S-hydroxycholesterol (cerebrosterol) is increased in Alzheimer and vascular demented patients, J Lipid Res 41 (2000) 195-198.
-
(2000)
J Lipid Res
, vol.41
, pp. 195-198
-
-
Lutjohann, D.1
Papassotiropoulos, A.2
Bjorkhem, I.3
Locatelli, S.4
Bagli, M.5
Oehring, R.D.6
Schlegel, U.7
Jessen, F.8
Rao, M.L.9
von Bergmann, K.10
Heun, R.11
-
58
-
-
0028173205
-
Amyloid-associated proteins alpha 1-antichymotrypsin and apolipoprotein E promote assembly of Alzheimer betaprotein into filaments
-
J. Ma, A. Yee, H.B. Brewer, S. Jr. Das and H. Potter, Amyloid-associated proteins alpha 1-antichymotrypsin and apolipoprotein E promote assembly of Alzheimer betaprotein into filaments, Nature 372 (1994), 92-94.
-
(1994)
Nature
, vol.372
, pp. 92-94
-
-
Ma, J.1
Yee, A.2
Brewer, H.B.3
Das Jr., S.4
Potter, H.5
-
59
-
-
0024299370
-
Apolipoprotein E: Cholesterol transport protein with expanding role in cell biology
-
R.W. Mahley, Apolipoprotein E: cholesterol transport protein with expanding role in cell biology, Science 240 (1988), 622-630.
-
(1988)
Science
, vol.240
, pp. 622-630
-
-
Mahley, R.W.1
-
60
-
-
0036046427
-
Does caffeine intake protect from Alzheimer's disease?
-
L. Maia, A. deMendonca, Does caffeine intake protect from Alzheimer's disease?, Eur J Neurol 9 (2002), 377-382.
-
(2002)
Eur J Neurol
, vol.9
, pp. 377-382
-
-
Maia, L.1
deMendonca, A.2
-
61
-
-
0642371716
-
Beta-secretase processing of the Alzheimer's amyloid protein precursor (APP)
-
L. Marlow, M. Cain, M.A. Pappolla and K. Sambamurti, Beta-secretase processing of the Alzheimer's amyloid protein precursor (APP), J Mol Neurosci 20 (2003), 233-239.
-
(2003)
J Mol Neurosci
, vol.20
, pp. 233-239
-
-
Marlow, L.1
Cain, M.2
Pappolla, M.A.3
Sambamurti, K.4
-
62
-
-
0027157066
-
Caffeine-stimulated Ca2+ release from the intracellular stores of hepatocytes is not mediated by ryanodine receptors
-
T.J. McNulty and C.W. Taylor, Caffeine-stimulated Ca2+ release from the intracellular stores of hepatocytes is not mediated by ryanodine receptors, Biochem J 291 (1993), 799-801.
-
(1993)
Biochem J
, vol.291
, pp. 799-801
-
-
McNulty, T.J.1
Taylor, C.W.2
-
63
-
-
33644850568
-
Brain and brawn: Parallels in oxidative strength
-
P.I. Moreira, K. Honda, X. Zhu, A. Nunomura, G. Casadesus, M.A. Smith and G. Perry, Brain and brawn: parallels in oxidative strength, Neurology 66 (2006), 97-101.
-
(2006)
Neurology
, vol.66
, pp. 97-101
-
-
Moreira, P.I.1
Honda, K.2
Zhu, X.3
Nunomura, A.4
Casadesus, G.5
Smith, M.A.6
Perry, G.7
-
64
-
-
0036150827
-
Alzheimer's disease-do tauists and baptists finally shake hands?
-
A. Mudher and S. Lovestone, Alzheimer's disease-do tauists and baptists finally shake hands? Trends Neurosci 25 (2002), 22-26.
-
(2002)
Trends Neurosci
, vol.25
, pp. 22-26
-
-
Mudher, A.1
Lovestone, S.2
-
65
-
-
0027477297
-
Apolipoprotein E polymorphism is associated with plasma cholesterol response in a 7-day hospitalization study for metabolic and dietary control in NIDDM
-
K. Murakami, M. Shimizu, N. Yamada, S. Ishibashi, H. Shimano, Y. Yazaki and Y. Akanuma, Apolipoprotein E polymorphism is associated with plasma cholesterol response in a 7-day hospitalization study for metabolic and dietary control in NIDDM, Diabetes Care 16 (1993), 564-569.
-
(1993)
Diabetes Care
, vol.16
, pp. 564-569
-
-
Murakami, K.1
Shimizu, M.2
Yamada, N.3
Ishibashi, S.4
Shimano, H.5
Yazaki, Y.6
Akanuma, Y.7
-
66
-
-
0344845132
-
Amyloid deposition precedes tangle formation in a triple transgenic model of Alzheimer's disease
-
S. Oddo, A. Caccamo, M. Kitazawa, B.P. Tseng and F.M. LaFerla, Amyloid deposition precedes tangle formation in a triple transgenic model of Alzheimer's disease, Neurobiol Aging 24 (2003), 1063-1070.
-
(2003)
Neurobiol Aging
, vol.24
, pp. 1063-1070
-
-
Oddo, S.1
Caccamo, A.2
Kitazawa, M.3
Tseng, B.P.4
LaFerla, F.M.5
-
67
-
-
0004821712
-
Plasma 24S-hydroxycholesterol: A peripheral indicator of neuronal degeneration and potential state marker for Alzheimer's disease
-
A. Papassotiropoulos, D. Lutjohann, M. Bagli, S. Locatelli, F. Jessen, M.L. Rao, W. Maier, I. Bjorkhem, K. vonBergmann and R. Heun, Plasma 24S-hydroxycholesterol: a peripheral indicator of neuronal degeneration and potential state marker for Alzheimer's disease, Neuroreport 11 (2000), 1959-1962.
-
(2000)
Neuroreport
, vol.11
, pp. 1959-1962
-
-
Papassotiropoulos, A.1
Lutjohann, D.2
Bagli, M.3
Locatelli, S.4
Jessen, F.5
Rao, M.L.6
Maier, W.7
Bjorkhem, I.8
vonBergmann, K.9
Heun, R.10
-
68
-
-
0037227538
-
Increased brain beta-amyloid load, phosphorylated tau, and risk of Alzheimer disease associated with an intronic CYP46 polymorphism
-
A. Papassotiropoulos, J.R. Streffer, M. Tsolaki, S. Schmid, D. Thal, F. Nicosia, V. Iakovidou, A. Maddalena, D. Lutjohann, E. Ghebremedhin, T. Hegi, T. Pasch, M. Traxler, A. Bruhl, L. Benussi, G. Binetti, H. Braak, R.M. Nitsch and C. Hock, Increased brain beta-amyloid load, phosphorylated tau, and risk of Alzheimer disease associated with an intronic CYP46 polymorphism, Arch Neurol 60 (2003), 29-35.
-
(2003)
Arch Neurol
, vol.60
, pp. 29-35
-
-
Papassotiropoulos, A.1
Streffer, J.R.2
Tsolaki, M.3
Schmid, S.4
Thal, D.5
Nicosia, F.6
Iakovidou, V.7
Maddalena, A.8
Lutjohann, D.9
Ghebremedhin, E.10
Hegi, T.11
Pasch, T.12
Traxler, M.13
Bruhl, A.14
Benussi, L.15
Binetti, G.16
Braak, H.17
Nitsch, R.M.18
Hock, C.19
-
69
-
-
0036121232
-
Statins inhibit A beta-neurotoxicity in vitro and A beta-induced vasoconstriction and inflammation in rat aortae
-
D. Paris, K.P. Townsend, J. Humphrey, D.F. Obregon, K. Yokota and M. Mullan, Statins inhibit A beta-neurotoxicity in vitro and A beta-induced vasoconstriction and inflammation in rat aortae, Atherosclerosis 161 (2002), 293-299.
-
(2002)
Atherosclerosis
, vol.161
, pp. 293-299
-
-
Paris, D.1
Townsend, K.P.2
Humphrey, J.3
Obregon, D.F.4
Yokota, K.5
Mullan, M.6
-
70
-
-
0037710127
-
Cholesterol homeostasis and function in neurons of the central nervous system
-
F.W. Pfrieger, Cholesterol homeostasis and function in neurons of the central nervous system, Cell Mol Life Sci 60 (2003), 1158-1171.
-
(2003)
Cell Mol Life Sci
, vol.60
, pp. 1158-1171
-
-
Pfrieger, F.W.1
-
71
-
-
0027298061
-
Cholesterol synthesis and lipoprotein reuptake during synaptic remodelling in hippocampus in adult rats
-
J. Poirier, A. Baccichet, D. Dea and S. Gauthier, Cholesterol synthesis and lipoprotein reuptake during synaptic remodelling in hippocampus in adult rats, Neuroscience 55 (1993), 81-90.
-
(1993)
Neuroscience
, vol.55
, pp. 81-90
-
-
Poirier, J.1
Baccichet, A.2
Dea, D.3
Gauthier, S.4
-
72
-
-
0032528909
-
Expression of ryanodine receptors in human embryonic kidney (HEK293) cells
-
H.W. Querfurth, N.J. Haughey, S.C. Greenway, P.W. Yacono, D.E. Golan and J.D. Geiger, Expression of ryanodine receptors in human embryonic kidney (HEK293) cells, Biochem J 334 (1998), 79-86.
-
(1998)
Biochem J
, vol.334
, pp. 79-86
-
-
Querfurth, H.W.1
Haughey, N.J.2
Greenway, S.C.3
Yacono, P.W.4
Golan, D.E.5
Geiger, J.D.6
-
73
-
-
17644429206
-
Secretory processing of amyloid precursor protein is inhibited by increase in cellular cholesterol content
-
M. Racchi, R. Baetta, N. Salvietti, P. Ianna, G. Franceschini, R. Paoletti, R. Fumagalli, S. Govoni, M. Trabucchi and M. Soma, Secretory processing of amyloid precursor protein is inhibited by increase in cellular cholesterol content, Biochem J 322 (1997), 893-898.
-
(1997)
Biochem J
, vol.322
, pp. 893-898
-
-
Racchi, M.1
Baetta, R.2
Salvietti, N.3
Ianna, P.4
Franceschini, G.5
Paoletti, R.6
Fumagalli, R.7
Govoni, S.8
Trabucchi, M.9
Soma, M.10
-
74
-
-
0037197836
-
Tau is essential to beta -amyloid-induced neurotoxicity
-
M. Rapoport, H.N. Dawson, L.I. Binder, M.P. Vitek and A. Ferreira, Tau is essential to beta -amyloid-induced neurotoxicity, Proc Natl Acad Sci USA 99 (2002), 6364-6369.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 6364-6369
-
-
Rapoport, M.1
Dawson, H.N.2
Binder, L.I.3
Vitek, M.P.4
Ferreira, A.5
-
75
-
-
22844431778
-
Statin use and the risk of incident dementia: The Cardiovascular Health Study
-
T.D. Rea, J.C. Breitner, B.M. Psaty, A.L. Fitzpatrick, O.L. Lopez, A.B. Newman, W.R. Hazzard, P.P. Zandi, G.L. Burke, C.G. Lyketsos, C. Bernick and L.H. Kuller, Statin use and the risk of incident dementia: the Cardiovascular Health Study, Arch Neurol 62 (2005), 1047-1051.
-
(2005)
Arch Neurol
, vol.62
, pp. 1047-1051
-
-
Rea, T.D.1
Breitner, J.C.2
Psaty, B.M.3
Fitzpatrick, A.L.4
Lopez, O.L.5
Newman, A.B.6
Hazzard, W.R.7
Zandi, P.P.8
Burke, G.L.9
Lyketsos, C.G.10
Bernick, C.11
Kuller, L.H.12
-
76
-
-
0033833354
-
Hypercholesterolemia accelerates the Alzheimer's amyloid pathology in a transgenic mouse model
-
L.M. Refolo, B. Malester, J. LaFrancois, T. Bryant-Thomas, R. Wang, G.S. Tint, K. Sambamurti, K. Duff and M.A. Pappolla, Hypercholesterolemia accelerates the Alzheimer's amyloid pathology in a transgenic mouse model, Neurobiol Dis 7 (2000), 321-331.
-
(2000)
Neurobiol Dis
, vol.7
, pp. 321-331
-
-
Refolo, L.M.1
Malester, B.2
LaFrancois, J.3
Bryant-Thomas, T.4
Wang, R.5
Tint, G.S.6
Sambamurti, K.7
Duff, K.8
Pappolla, M.A.9
-
77
-
-
33847006236
-
Effect of statins on Alzheimer's disease biomarkers in cerebrospinal fluid
-
R.G. Riekse, G. Li, E.C. Petrie, J.B. Leverenz, D. Vavrek, S. Vuletic, J.J. Albers, T.J. Montine, V.M. Lee, M. Lee, P. Seubert, D. Galasko, G.D. Schellenberg, W.R. Hazzard and E.R. Peskind, Effect of statins on Alzheimer's disease biomarkers in cerebrospinal fluid, J Alzheimers Dis 10 (2006), 399-406.
-
(2006)
J Alzheimers Dis
, vol.10
, pp. 399-406
-
-
Riekse, R.G.1
Li, G.2
Petrie, E.C.3
Leverenz, J.B.4
Vavrek, D.5
Vuletic, S.6
Albers, J.J.7
Montine, T.J.8
Lee, V.M.9
Lee, M.10
Seubert, P.11
Galasko, D.12
Schellenberg, G.D.13
Hazzard, W.R.14
Peskind, E.R.15
-
78
-
-
0034672672
-
Oxysterol biosynthetic enzymes
-
D.W. Russell, Oxysterol biosynthetic enzymes, Biochim Biophys Acta 1529 (2000), 126-135.
-
(2000)
Biochim Biophys Acta
, vol.1529
, pp. 126-135
-
-
Russell, D.W.1
-
79
-
-
0028281788
-
In vivo and in vitro blood-brain barrier transport of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitors
-
A. Saheki, T. Terasaki, I. Tamai and A. Tsuji, In vivo and in vitro blood-brain barrier transport of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitors, Pharm Res 11 (1994), 305-311.
-
(1994)
Pharm Res
, vol.11
, pp. 305-311
-
-
Saheki, A.1
Terasaki, T.2
Tamai, I.3
Tsuji, A.4
-
80
-
-
20044370505
-
High cholesterol level is essential for myelin membrane growth
-
G. Saher, B. Brugger, C. Lappe-Siefke, W. Mobius, R. Tozawa, M.C. Wehr, F. Wieland, S. Ishibashi and K.A. Nave, High cholesterol level is essential for myelin membrane growth, Nat Neurosci 8 (2005), 468-475.
-
(2005)
Nat Neurosci
, vol.8
, pp. 468-475
-
-
Saher, G.1
Brugger, B.2
Lappe-Siefke, C.3
Mobius, W.4
Tozawa, R.5
Wehr, M.C.6
Wieland, F.7
Ishibashi, S.8
Nave, K.A.9
-
81
-
-
0027327267
-
Association of apolipoprotein E allele epsilon 4 with late-onset familial and sporadic Alzheimer's disease
-
A.M. Saunders, W.J. Strittmatter, D. Schmechel, P.H. George-Hyslop, M.A. Pericak-Vance, S.H. Joo, B.L. Rosi, J.F. Gusella, D.R. Crapper-MacLachlan and M.J. Alberts, Association of apolipoprotein E allele epsilon 4 with late-onset familial and sporadic Alzheimer's disease, Neurology 43 (1993), 1467-1472.
-
(1993)
Neurology
, vol.43
, pp. 1467-1472
-
-
Saunders, A.M.1
Strittmatter, W.J.2
Schmechel, D.3
George-Hyslop, P.H.4
Pericak-Vance, M.A.5
Joo, S.H.6
Rosi, B.L.7
Gusella, J.F.8
Crapper-MacLachlan, D.R.9
Alberts, M.J.10
-
82
-
-
0036694086
-
ABCA2: A candidate regulator of neural transmembrane lipid transport
-
G. Schmitz and W. E. Kaminski, ABCA2: a candidate regulator of neural transmembrane lipid transport, Cell Mol Life Sci 59 (2002), 1285-1295.
-
(2002)
Cell Mol Life Sci
, vol.59
, pp. 1285-1295
-
-
Schmitz, G.1
Kaminski, W.E.2
-
83
-
-
40849102760
-
Hippocampus of Ames dwarf mice is resistant to beta-amyloid-induced tau hyperphosphorylation and changes in apoptosisregulatory protein levels
-
M. Schrag, S. Sharma, H. Brown-Borg and O. Ghribi, Hippocampus of Ames dwarf mice is resistant to beta-amyloid-induced tau hyperphosphorylation and changes in apoptosisregulatory protein levels, Hippocampus 18 (2008), 239-244.
-
(2008)
Hippocampus
, vol.18
, pp. 239-244
-
-
Schrag, M.1
Sharma, S.2
Brown-Borg, H.3
Ghribi, O.4
-
84
-
-
0037171095
-
Diet-induced hypercholesterolemia enhances brain A beta accumulation in transgenic mice
-
F.S. Shie, L.W. Jin, D.G. Cook, J.B. Leverenz and R.C. LeBoeuf, Diet-induced hypercholesterolemia enhances brain A beta accumulation in transgenic mice, Neuroreport 13 (2002), 455-459.
-
(2002)
Neuroreport
, vol.13
, pp. 455-459
-
-
Shie, F.S.1
Jin, L.W.2
Cook, D.G.3
Leverenz, J.B.4
LeBoeuf, R.C.5
-
85
-
-
0032568552
-
Cholesterol depletion inhibits the generation of beta-amyloid in hippocampal neurons
-
M. Simons, P. Keller, B. De Strooper, K. Beyreuther, C. G. Dotti and K. Simons, Cholesterol depletion inhibits the generation of beta-amyloid in hippocampal neurons, Proc Natl Acad Sci USA 95 (1998), 6460-6464.
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 6460-6464
-
-
Simons, M.1
Keller, P.2
De Strooper, B.3
Beyreuther, K.4
Dotti, C.G.5
Simons, K.6
-
86
-
-
0037262480
-
Treatment with simvastatin in patients with Alzheimer's disease lowers both alpha- and beta-cleaved amyloid precursor protein
-
M. Sjogren, K. Gustafsson, S. Syversen, A. Olsson, A. Edman, P. Davidsson, A. Wallin and K. Blennow, Treatment with simvastatin in patients with Alzheimer's disease lowers both alpha- and beta-cleaved amyloid precursor protein, Dement Geriatr Cogn Disord 16 (2003), 25-30.
-
(2003)
Dement Geriatr Cogn Disord
, vol.16
, pp. 25-30
-
-
Sjogren, M.1
Gustafsson, K.2
Syversen, S.3
Olsson, A.4
Edman, A.5
Davidsson, P.6
Wallin, A.7
Blennow, K.8
-
87
-
-
58149380391
-
The early and ongoing experience with the cholesterol-fed rabbit as a model of Alzheimer's disease: The old, the new and the pilot
-
D.L. Sparks, The early and ongoing experience with the cholesterol-fed rabbit as a model of Alzheimer's disease: the old, the new and the pilot, J Alzheimers Dis 15(4) (2008), 641-656.
-
(2008)
J Alzheimers Dis
, vol.15
, Issue.4
, pp. 641-656
-
-
Sparks, D.L.1
-
88
-
-
0028902073
-
Increased density of cortical apolipoprotein E immunoreactive neurons in rabbit brain after dietary administration of cholesterol
-
D.L. Sparks, H. Liu, D.R. Gross and S.W. Scheff, Increased density of cortical apolipoprotein E immunoreactive neurons in rabbit brain after dietary administration of cholesterol, Neurosci Lett 187 (1995), 142-144.
-
(1995)
Neurosci Lett
, vol.187
, pp. 142-144
-
-
Sparks, D.L.1
Liu, H.2
Gross, D.R.3
Scheff, S.W.4
-
89
-
-
0028177562
-
Induction of Alzheimer-like betaamyloid immunoreactivity in the brains of rabbits with dietary cholesterol
-
D.L. Sparks, S.W. Scheff, J.C. Hunsaker, III, H. Liu, T. Landers and D.R. Gross, Induction of Alzheimer-like betaamyloid immunoreactivity in the brains of rabbits with dietary cholesterol, Exp Neurol 126 (1994), 88-94.
-
(1994)
Exp Neurol
, vol.126
, pp. 88-94
-
-
Sparks, D.L.1
Scheff, S.W.2
Hunsaker III, J.C.3
Liu, H.4
Landers, T.5
Gross, D.R.6
-
90
-
-
0025805120
-
A simple method for organotypic cultures of nervous tissue
-
L. Stoppini, P.A. Buchs and D. Muller, A simple method for organotypic cultures of nervous tissue, J Neurosci Methods 37 (1991), 173-182.
-
(1991)
J Neurosci Methods
, vol.37
, pp. 173-182
-
-
Stoppini, L.1
Buchs, P.A.2
Muller, D.3
-
91
-
-
0027407565
-
Apolipoprotein E: High-avidity binding to beta-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease
-
W.J. Strittmatter, A.M. Saunders, D. Schmechel, M. Pericak-Vance, J. Enghild, G.S. Salvesen and A.D. Roses, Apolipoprotein E: high-avidity binding to beta-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease, Proc Natl Acad Sci USA 90 (1993), 1977-1981.
-
(1993)
Proc Natl Acad Sci USA
, vol.90
, pp. 1977-1981
-
-
Strittmatter, W.J.1
Saunders, A.M.2
Schmechel, D.3
Pericak-Vance, M.4
Enghild, J.5
Salvesen, G.S.6
Roses, A.D.7
-
92
-
-
0038458980
-
Statins as potential therapeutic agents in neuroinflammatory disorders
-
O. Stuve, S. Youssef, L. Steinman and S.S. Zamvil, Statins as potential therapeutic agents in neuroinflammatory disorders, Curr Opin Neurol 16 (2003), 393-401.
-
(2003)
Curr Opin Neurol
, vol.16
, pp. 393-401
-
-
Stuve, O.1
Youssef, S.2
Steinman, L.3
Zamvil, S.S.4
-
93
-
-
0042346382
-
Expression of liver X receptor target genes decreases cellular amyloid beta peptide secretion
-
Y. Sun, J. Yao, T.W. Kim and A.R. Tall, Expression of liver X receptor target genes decreases cellular amyloid beta peptide secretion, J Biol Chem 278 (2003), 27688-27694.
-
(2003)
J Biol Chem
, vol.278
, pp. 27688-27694
-
-
Sun, Y.1
Yao, J.2
Kim, T.W.3
Tall, A.R.4
-
94
-
-
85187724973
-
-
Y.X. Sun, M. Crisby, S. Lindgren and S. Janciauskiene, Pravastatin inhibits pro-inflammatory effects of Alzheimer's peptide Abeta(1-42) in glioma cell culture in vitro, Pharmacol Res 47 (2003), 119-126.
-
Y.X. Sun, M. Crisby, S. Lindgren and S. Janciauskiene, Pravastatin inhibits pro-inflammatory effects of Alzheimer's peptide Abeta(1-42) in glioma cell culture in vitro, Pharmacol Res 47 (2003), 119-126.
-
-
-
-
95
-
-
56349160982
-
Hypercholesterolemia-induced Abeta accumulation in rabbit brain is associated with alteration in IGF-1 signaling
-
in press
-
S. Sharma, J. Prasanthi, E. Schommer, G. Feist and O. Ghribi, Hypercholesterolemia-induced Abeta accumulation in rabbit brain is associated with alteration in IGF-1 signaling. Neurobiol Dis (2008), in press.
-
(2008)
Neurobiol Dis
-
-
Sharma, S.1
Prasanthi, J.2
Schommer, E.3
Feist, G.4
Ghribi, O.5
-
96
-
-
0031695652
-
Activation of tau protein kinase I/glycogen synthase kinase-3beta by amyloid beta peptide (25-35) enhances phosphorylation of tau in hippocampal neurons
-
A. Takashima, T. Honda, K. Yasutake, G. Michel, O. Murayama, M. Murayama, K. Ishiguro and H. Yamaguchi, Activation of tau protein kinase I/glycogen synthase kinase-3beta by amyloid beta peptide (25-35) enhances phosphorylation of tau in hippocampal neurons, Neurosci Res 31 (1998), 317-323.
-
(1998)
Neurosci Res
, vol.31
, pp. 317-323
-
-
Takashima, A.1
Honda, T.2
Yasutake, K.3
Michel, G.4
Murayama, O.5
Murayama, M.6
Ishiguro, K.7
Yamaguchi, H.8
-
97
-
-
34248144337
-
The cholesterol transporter ABCG1 modulates the subcellular distribution and proteolytic processing of beta-amyloid precursor protein
-
G.H. Tansley, B.L. Burgess, M.T. Bryan, Y. Su, V. Hirsch-Reinshagen, J. Pearce, J.Y. Chan, A. Wilkinson, J. Evans, K.E. Naus, S. McIsaac, K. Bromley, W. Song, H.C. Yang, N. Wang, R.B. DeMattos and C.L. Wellington, The cholesterol transporter ABCG1 modulates the subcellular distribution and proteolytic processing of beta-amyloid precursor protein, J Lipid Res 48 (2007), 1022-1034.
-
(2007)
J Lipid Res
, vol.48
, pp. 1022-1034
-
-
Tansley, G.H.1
Burgess, B.L.2
Bryan, M.T.3
Su, Y.4
Hirsch-Reinshagen, V.5
Pearce, J.6
Chan, J.Y.7
Wilkinson, A.8
Evans, J.9
Naus, K.E.10
McIsaac, S.11
Bromley, K.12
Song, W.13
Yang, H.C.14
Wang, N.15
DeMattos, R.B.16
Wellington, C.L.17
-
98
-
-
30044442937
-
Deletion of Abca1 increases Abeta deposition in the PDAPP transgenic mouse model of Alzheimer disease
-
S.E. Wahrle, H. Jiang, M. Parsadanian, R.E. Hartman, K.R. Bales, S.M. Paul and D.M. Holtzman, Deletion of Abca1 increases Abeta deposition in the PDAPP transgenic mouse model of Alzheimer disease, J Biol Chem 280 (2005), 43236-43242.
-
(2005)
J Biol Chem
, vol.280
, pp. 43236-43242
-
-
Wahrle, S.E.1
Jiang, H.2
Parsadanian, M.3
Hartman, R.E.4
Bales, K.R.5
Paul, S.M.6
Holtzman, D.M.7
-
99
-
-
0037108819
-
Liver X receptors in the central nervous system: From lipid homeostasis to neuronal degeneration
-
L. Wang, G.U. Schuster, K. Hultenby, Q. Zhang, S. Andersson and J.A. Gustafsson, Liver X receptors in the central nervous system: from lipid homeostasis to neuronal degeneration, Proc Natl Acad Sci USA 99 (2002), 13878-13883.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 13878-13883
-
-
Wang, L.1
Schuster, G.U.2
Hultenby, K.3
Zhang, Q.4
Andersson, S.5
Gustafsson, J.A.6
-
100
-
-
0347318065
-
Cholesterol and the biology of Alzheimer's disease
-
B. Wolozin, Cholesterol and the biology of Alzheimer's disease, Neuron 41 (2004), 7-10.
-
(2004)
Neuron
, vol.41
, pp. 7-10
-
-
Wolozin, B.1
-
101
-
-
3042770616
-
The cellular biochemistry of cholesterol and statins: Insights into the pathophysiology and therapy of Alzheimer's disease
-
B. Wolozin, J. Brown, III, C. Theisler and S. Silberman, The cellular biochemistry of cholesterol and statins: insights into the pathophysiology and therapy of Alzheimer's disease, CNS Drug Rev 10 (2004), 127-146.
-
(2004)
CNS Drug Rev
, vol.10
, pp. 127-146
-
-
Wolozin, B.1
Brown III, J.2
Theisler, C.3
Silberman, S.4
-
102
-
-
34447628317
-
A rabbit model of Alzheimer's disease: Valid at neuropathological, cognitive, and therapeutic levels
-
D.S. Woodruff-Pak, A. Agelan and V.L. Del, A rabbit model of Alzheimer's disease: valid at neuropathological, cognitive, and therapeutic levels, J Alzheimers Dis 11 (2007), 371-383.
-
(2007)
J Alzheimers Dis
, vol.11
, pp. 371-383
-
-
Woodruff-Pak, D.S.1
Agelan, A.2
Del, V.L.3
-
103
-
-
0037236622
-
Elevated beta-secretase expression and enzymatic activity detected in sporadic Alzheimer disease
-
L.B. Yang, K. Lindholm, R. Yan, M. Citron, W. Xia, X.L. Yang, T. Beach, L. Sue, P.Wong, D. Price, R. Li and Y. Shen, Elevated beta-secretase expression and enzymatic activity detected in sporadic Alzheimer disease, Nat Med 9 (2003), 3-4.
-
(2003)
Nat Med
, vol.9
, pp. 3-4
-
-
Yang, L.B.1
Lindholm, K.2
Yan, R.3
Citron, M.4
Xia, W.5
Yang, X.L.6
Beach, T.7
Sue, L.8
Wong, P.9
Price, D.10
Li, R.11
Shen, Y.12
-
104
-
-
13244295723
-
Do statins reduce risk of incident dementia and Alzheimer disease? The Cache County Study
-
P.P. Zandi, D.L. Sparks, A.S. Khachaturian, J. Tschanz, M. Norton, M. Steinberg, K.A.Welsh-Bohmer and J.C. Breitner, Do statins reduce risk of incident dementia and Alzheimer disease? The Cache County Study, Arch Gen Psychiatry 62 (2005), 217-224.
-
(2005)
Arch Gen Psychiatry
, vol.62
, pp. 217-224
-
-
Zandi, P.P.1
Sparks, D.L.2
Khachaturian, A.S.3
Tschanz, J.4
Norton, M.5
Steinberg, M.6
Welsh-Bohmer, K.A.7
Breitner, J.C.8
-
105
-
-
0035112624
-
Atp-binding cassette transporter ABC2/ABCA2 in the rat brain: A novel mammalian lysosome-associated membrane protein and a specific marker for oligodendrocytes but not for myelin sheaths
-
C. Zhou, L. Zhao, N. Inagaki, J. Guan, S. Nakajo, T. Hirabayashi, S. Kikuyama and S. Shioda, Atp-binding cassette transporter ABC2/ABCA2 in the rat brain: a novel mammalian lysosome-associated membrane protein and a specific marker for oligodendrocytes but not for myelin sheaths, J Neurosci 21 (2001), 849-857.
-
(2001)
J Neurosci
, vol.21
, pp. 849-857
-
-
Zhou, C.1
Zhao, L.2
Inagaki, N.3
Guan, J.4
Nakajo, S.5
Hirabayashi, T.6
Kikuyama, S.7
Shioda, S.8
|