-
2
-
-
34247464737
-
Inflammation and anti-inflammatory therapies for cystic fibrosis
-
Chmiel JF, Konstan MW. Inflammation and anti-inflammatory therapies for cystic fibrosis. Clin Chest Med 2007; 28: 331-346.
-
(2007)
Clin Chest Med
, vol.28
, pp. 331-346
-
-
Chmiel, J.F.1
Konstan, M.W.2
-
3
-
-
33847357783
-
Misassembled mutant ΔF508 CFTR in the distal secretory pathway alters cellular lipid trafficking
-
Gentzsch M, Choudhury A, Chang XB, Pagano RE, Riordan JR. Misassembled mutant ΔF508 CFTR in the distal secretory pathway alters cellular lipid trafficking. J Cell Sci 2007; 120: 447-455.
-
(2007)
J Cell Sci
, vol.120
, pp. 447-455
-
-
Gentzsch, M.1
Choudhury, A.2
Chang, X.B.3
Pagano, R.E.4
Riordan, J.R.5
-
5
-
-
0042934009
-
Effect of ibuprofen on neutrophil migration in vivo in cystic fibrosis and healthy subjects
-
Konstan MW, Krenicky JE, Finney MR, et al. Effect of ibuprofen on neutrophil migration in vivo in cystic fibrosis and healthy subjects. J Pharmacol Exp Ther 2003; 306: 1086-1091.
-
(2003)
J Pharmacol Exp Ther
, vol.306
, pp. 1086-1091
-
-
Konstan, M.W.1
Krenicky, J.E.2
Finney, M.R.3
-
6
-
-
36848999782
-
Clinical use of ibuprofen is associated with slower FEV1 decline in children with cystic fibrosis
-
Konstan MW, Schluchter MD, Xue W, Davis PB. Clinical use of ibuprofen is associated with slower FEV1 decline in children with cystic fibrosis. Am J Respir Crit Care Med 2007; 176: 1084-1089.
-
(2007)
Am J Respir Crit Care Med
, vol.176
, pp. 1084-1089
-
-
Konstan, M.W.1
Schluchter, M.D.2
Xue, W.3
Davis, P.B.4
-
7
-
-
10344250594
-
Effect of treatment with dornase alpha on airway inflammation in cystic fibrosis patients
-
Paul K, Rietschel E, Ballmann M, et al. Effect of treatment with dornase alpha on airway inflammation in cystic fibrosis patients. Am J Respir Crit Care Med 2004; 169: 719-725.
-
(2004)
Am J Respir Crit Care Med
, vol.169
, pp. 719-725
-
-
Paul, K.1
Rietschel, E.2
Ballmann, M.3
-
8
-
-
33745130682
-
Multicenter randomized controlled trial of withdrawal of inhaled corticosteroids in cystic fibrosis
-
Balfour-Lynn IM, Lees B, Hall P, et al. Multicenter randomized controlled trial of withdrawal of inhaled corticosteroids in cystic fibrosis. Am J Respir Crit Care Med 2006; 173: 1356-1362.
-
(2006)
Am J Respir Crit Care Med
, vol.173
, pp. 1356-1362
-
-
Balfour-Lynn, I.M.1
Lees, B.2
Hall, P.3
-
9
-
-
29144528654
-
4 receptor antagonist) for the treatment of CF lung disease
-
4 receptor antagonist) for the treatment of CF lung disease. Ped Pulm 2005; 40: Suppl. 28, 125-126.
-
(2005)
Ped Pulm
, vol.40
, Issue.SUPPL. 28
, pp. 125-126
-
-
Konstan, M.W.1
Doring, G.2
Lands, L.C.3
-
10
-
-
16344378766
-
Measuring and reporting quality of life outcomes in clinical trials in cystic fibrosis: A critical review
-
Abbott J, Hart A. Measuring and reporting quality of life outcomes in clinical trials in cystic fibrosis: a critical review. Health Qual Life Outcomes 2005; 24: 19.
-
(2005)
Health Qual Life Outcomes
, vol.24
, pp. 19
-
-
Abbott, J.1
Hart, A.2
-
11
-
-
0034821607
-
Defining a pulmonary exacerbation in cystic fibrosis
-
Rosenfeld M, Emerson J, Williams-Warren J, et al. Defining a pulmonary exacerbation in cystic fibrosis. J Pediatr 2001; 139: 359-365.
-
(2001)
J Pediatr
, vol.139
, pp. 359-365
-
-
Rosenfeld, M.1
Emerson, J.2
Williams-Warren, J.3
-
12
-
-
9644259076
-
Multiple breath inert gas washout as a measure of ventilation distribution in children with cystic fibrosis
-
Aurora P, Gustafsson P, Bush A, et al. Multiple breath inert gas washout as a measure of ventilation distribution in children with cystic fibrosis. Thorax 2004; 59: 1068-1073.
-
(2004)
Thorax
, vol.59
, pp. 1068-1073
-
-
Aurora, P.1
Gustafsson, P.2
Bush, A.3
-
13
-
-
0347766074
-
Progressive damage on high resolution computed tomography despite stable lung function in cystic fibrosis
-
de Jong PA, Nakano Y, Lequin MH, et al. Progressive damage on high resolution computed tomography despite stable lung function in cystic fibrosis. Eur Respir J 2004; 23: 93-97.
-
(2004)
Eur Respir J
, vol.23
, pp. 93-97
-
-
de Jong, P.A.1
Nakano, Y.2
Lequin, M.H.3
-
14
-
-
14844322136
-
Optimum peripheral drug deposition in patients with cystic fibrosis
-
Brand P, Meyer T, Häussermann S, et al. Optimum peripheral drug deposition in patients with cystic fibrosis. J Aerosol Med 2005; 18: 45-54.
-
(2005)
J Aerosol Med
, vol.18
, pp. 45-54
-
-
Brand, P.1
Meyer, T.2
Häussermann, S.3
-
15
-
-
0030768159
-
Lower airway inflammation in infants and young children with cystic fibrosis
-
Armstrong DS, Grimwood K, Carlin JB, et al. Lower airway inflammation in infants and young children with cystic fibrosis. Am J Respir Crit Care Med 1997; 156: 1197-1204.
-
(1997)
Am J Respir Crit Care Med
, vol.156
, pp. 1197-1204
-
-
Armstrong, D.S.1
Grimwood, K.2
Carlin, J.B.3
-
16
-
-
0036907325
-
Induced sputum inflammatory measures correlate with lung function in children with cystic fibrosis
-
Sagel SD, Sontag MK, Wagener JS, Kapsner RK, Osberg I, Accurso FJ. Induced sputum inflammatory measures correlate with lung function in children with cystic fibrosis. J Pediatr 2002; 141: 811-817.
-
(2002)
J Pediatr
, vol.141
, pp. 811-817
-
-
Sagel, S.D.1
Sontag, M.K.2
Wagener, J.S.3
Kapsner, R.K.4
Osberg, I.5
Accurso, F.J.6
-
17
-
-
0034131340
-
Fifteen-count breathlessness score: An objective measure for children
-
Prasad SA, Randall SD, Balfour-Lynn IM. Fifteen-count breathlessness score: an objective measure for children. Pediatr Pulmonol 2000; 30: 56-62.
-
(2000)
Pediatr Pulmonol
, vol.30
, pp. 56-62
-
-
Prasad, S.A.1
Randall, S.D.2
Balfour-Lynn, I.M.3
-
18
-
-
0027278897
-
Efficacy and safety of short-term administration of aerosolized recombinant human deoxyribonuclease in patients with cystic fibrosis
-
Ramsey BW, Astley S, Aitken M, et al. Efficacy and safety of short-term administration of aerosolized recombinant human deoxyribonuclease in patients with cystic fibrosis. Am Rev Respir Dis 1993; 148: 145-151.
-
(1993)
Am Rev Respir Dis
, vol.148
, pp. 145-151
-
-
Ramsey, B.W.1
Astley, S.2
Aitken, M.3
-
19
-
-
1642556721
-
Infection control in cystic fibrosis
-
Saiman L, Siegel J. Infection control in cystic fibrosis. Clin Microbiol Rev 2004; 17: 57-71.
-
(2004)
Clin Microbiol Rev
, vol.17
, pp. 57-71
-
-
Saiman, L.1
Siegel, J.2
-
20
-
-
34547731349
-
The effect of treatment of cystic fibrosis pulmonary exacerbations on airways and systemic inflammation
-
Downey DG, Brockbank S, Martin SL, Ennis M, Elborn JS. The effect of treatment of cystic fibrosis pulmonary exacerbations on airways and systemic inflammation. Pediatr Pulmonol 2007; 42: 729-735.
-
(2007)
Pediatr Pulmonol
, vol.42
, pp. 729-735
-
-
Downey, D.G.1
Brockbank, S.2
Martin, S.L.3
Ennis, M.4
Elborn, J.S.5
-
21
-
-
9144237586
-
Inflammatory and microbiologic markers in induced sputum after intravenous antibiotics in cystic fibrosis
-
Ordonez CL, Henig NR, Mayer-Hamblett N, et al. Inflammatory and microbiologic markers in induced sputum after intravenous antibiotics in cystic fibrosis. Am J Respir Crit Care Med 2003; 168: 1471-1475.
-
(2003)
Am J Respir Crit Care Med
, vol.168
, pp. 1471-1475
-
-
Ordonez, C.L.1
Henig, N.R.2
Mayer-Hamblett, N.3
-
22
-
-
33947263039
-
The relationship of clinical and inflammatory markers to outcome in stable patients with cystic fibrosis
-
Downey DG, Martin SL, Dempster M, et al. The relationship of clinical and inflammatory markers to outcome in stable patients with cystic fibrosis. Pediatr Pulmonol 2007; 42: 216-220.
-
(2007)
Pediatr Pulmonol
, vol.42
, pp. 216-220
-
-
Downey, D.G.1
Martin, S.L.2
Dempster, M.3
-
24
-
-
0028784322
-
Inflammatory cytokines in cystic fibrosis lungs
-
Bonfield TL. Inflammatory cytokines in cystic fibrosis lungs. Am J Respir Crit Care Med 1995; 152: 2111-2118.
-
(1995)
Am J Respir Crit Care Med
, vol.152
, pp. 2111-2118
-
-
Bonfield, T.L.1
-
25
-
-
0031836105
-
Mice lacking neutrophil elastase reveal impaired host defense against Gram negative bacterial sepsis
-
Belaaouaj A, McCarthy R, Baumann M, et al. Mice lacking neutrophil elastase reveal impaired host defense against Gram negative bacterial sepsis. Nat Med 1998; 4: 615-618.
-
(1998)
Nat Med
, vol.4
, pp. 615-618
-
-
Belaaouaj, A.1
McCarthy, R.2
Baumann, M.3
-
26
-
-
0036816820
-
Neutrophil elastase-mediated killing of bacteria: Lessons from targeted mutagenesis
-
Belaaouaj A. Neutrophil elastase-mediated killing of bacteria: lessons from targeted mutagenesis. Microbes Infect 2002; 4: 1259-1264.
-
(2002)
Microbes Infect
, vol.4
, pp. 1259-1264
-
-
Belaaouaj, A.1
-
27
-
-
1542287347
-
Neutrophil extracellular traps kill bacteria
-
Brinkmann V, Reichard U, Goosmann C, et al. Neutrophil extracellular traps kill bacteria. Science 2004; 303: 1532-1535.
-
(2004)
Science
, vol.303
, pp. 1532-1535
-
-
Brinkmann, V.1
Reichard, U.2
Goosmann, C.3
-
28
-
-
34447525439
-
Beneficial suicide: Why neutrophils die to make NETs
-
Brinkmann V, Zychlinsky A. Beneficial suicide: why neutrophils die to make NETs. Nat Rev Microbiol 2007; 5: 577-582.
-
(2007)
Nat Rev Microbiol
, vol.5
, pp. 577-582
-
-
Brinkmann, V.1
Zychlinsky, A.2
-
29
-
-
33846432787
-
Novel cell death program leads to neutrophil extracellular traps
-
Fuchs TA, Abed U, Goosmann C, et al. Novel cell death program leads to neutrophil extracellular traps. J Cell Biol 2007; 176: 231-241.
-
(2007)
J Cell Biol
, vol.176
, pp. 231-241
-
-
Fuchs, T.A.1
Abed, U.2
Goosmann, C.3
-
30
-
-
32944463724
-
Neutrophil extracellular traps capture and kill Candida albicans yeast and hyphal forms
-
Urban CF, Reichard U, Brinkmann V, Zychlinsky A. Neutrophil extracellular traps capture and kill Candida albicans yeast and hyphal forms. Cell Microbiol 2006; 8: 668-676.
-
(2006)
Cell Microbiol
, vol.8
, pp. 668-676
-
-
Urban, C.F.1
Reichard, U.2
Brinkmann, V.3
Zychlinsky, A.4
-
31
-
-
0021919760
-
Elastases and emphysema. Current assessment of the protease-antiprotease hypothesis
-
Janoff A. Elastases and emphysema. Current assessment of the protease-antiprotease hypothesis. Am Rev Respir Dis 1985; 132: 417-433.
-
(1985)
Am Rev Respir Dis
, vol.132
, pp. 417-433
-
-
Janoff, A.1
-
32
-
-
0025374343
-
Evaluation of elastase and antielastase balance in patients with chronic bronchitis and pulmonary emphysema
-
Fujita J, Nelson NL, Daughton DM, et al. Evaluation of elastase and antielastase balance in patients with chronic bronchitis and pulmonary emphysema. Am Rev Respir Dis 1990; 142: 57-62.
-
(1990)
Am Rev Respir Dis
, vol.142
, pp. 57-62
-
-
Fujita, J.1
Nelson, N.L.2
Daughton, D.M.3
-
33
-
-
0028240276
-
Protease-antiprotease imbalance in the lungs of children with cystic fibrosis
-
Birrer P, McElvaney N, Rüderberg A, et al. Protease-antiprotease imbalance in the lungs of children with cystic fibrosis. Am J Respir Crit Care Med 1994; 150: 207-213.
-
(1994)
Am J Respir Crit Care Med
, vol.150
, pp. 207-213
-
-
Birrer, P.1
McElvaney, N.2
Rüderberg, A.3
-
34
-
-
0022642346
-
Levels of free granulocyte elastase in bronchial secretions from patients with cystic fibrosis: Effect of antimicrobial treatment against Pseudomonas aeruginosa
-
Suter S, Schaad UB, Tegner H, Ohlsson K, Desgrandchamps D, Waldvogel FA. Levels of free granulocyte elastase in bronchial secretions from patients with cystic fibrosis: effect of antimicrobial treatment against Pseudomonas aeruginosa. J Infect Dis 1986; 153: 902-909.
-
(1986)
J Infect Dis
, vol.153
, pp. 902-909
-
-
Suter, S.1
Schaad, U.B.2
Tegner, H.3
Ohlsson, K.4
Desgrandchamps, D.5
Waldvogel, F.A.6
-
35
-
-
0022496447
-
Imbalance between polymorphonuclear leukocyte proteases and antiproteases in chronic pyogenic infections and its relation to the proteolysis of complement component C3
-
Suter S. Imbalance between polymorphonuclear leukocyte proteases and antiproteases in chronic pyogenic infections and its relation to the proteolysis of complement component C3. Complement 1986; 3: 1-24.
-
(1986)
Complement
, vol.3
, pp. 1-24
-
-
Suter, S.1
-
36
-
-
0027131471
-
1- Proteinase inhibitor, elastase activity, and lung disease severity in cystic fibrosis
-
1- Proteinase inhibitor, elastase activity, and lung disease severity in cystic fibrosis. Am Rev Respir Dis 1993; 148: 1665-1670.
-
(1993)
Am Rev Respir Dis
, vol.148
, pp. 1665-1670
-
-
O'Connor, C.M.1
Gaffney, K.2
Keane, J.3
-
37
-
-
0027998135
-
The role of neutrophil elastase in chronic inflammation
-
Döring G. The role of neutrophil elastase in chronic inflammation. Am J Respir Crit Care Med 1994; 150: 114-117.
-
(1994)
Am J Respir Crit Care Med
, vol.150
, pp. 114-117
-
-
Döring, G.1
-
38
-
-
0031443570
-
Inhibition of neutrophil elastase in CF sputum by L-658,758
-
Rees DD, Brain JD, Wohl ME, Humes JL, Mumford RA. Inhibition of neutrophil elastase in CF sputum by L-658,758. J Pharmacol Exp Ther 1997; 283: 1201-1206.
-
(1997)
J Pharmacol Exp Ther
, vol.283
, pp. 1201-1206
-
-
Rees, D.D.1
Brain, J.D.2
Wohl, M.E.3
Humes, J.L.4
Mumford, R.A.5
-
39
-
-
0014886090
-
Mediators of tissue damage in human polymorphonuclear neutrophils
-
Janoff A. Mediators of tissue damage in human polymorphonuclear neutrophils. Ser Haematol 1970; 3: 96-130.
-
(1970)
Ser Haematol
, vol.3
, pp. 96-130
-
-
Janoff, A.1
-
40
-
-
0015403725
-
Human granulocyte elastase. Further delineation of its role in connective tissue damage
-
Janoff A. Human granulocyte elastase. Further delineation of its role in connective tissue damage. Am J Pathol 1972; 68: 579-592.
-
(1972)
Am J Pathol
, vol.68
, pp. 579-592
-
-
Janoff, A.1
-
41
-
-
0015441585
-
Neutrophil proteases in inflammation
-
Janoff A. Neutrophil proteases in inflammation. Annu Rev Med 1972; 23: 177-190.
-
(1972)
Annu Rev Med
, vol.23
, pp. 177-190
-
-
Janoff, A.1
-
42
-
-
0020623852
-
Proteases and lung injury. A state-of-the-art minireview
-
Janoff A. Proteases and lung injury. A state-of-the-art minireview. Chest 1983; 83: Suppl. 5, 54S-58S.
-
(1983)
Chest
, vol.83
, Issue.SUPPL. 5
-
-
Janoff, A.1
-
43
-
-
0021941090
-
Elastase in tissue injury
-
Janoff A. Elastase in tissue injury. Annu Rev Med 1985; 36: 207-216.
-
(1985)
Annu Rev Med
, vol.36
, pp. 207-216
-
-
Janoff, A.1
-
44
-
-
0023837944
-
Inactivation of tissue inhibitor of metalloproteinases by neutrophil elastase and other serine proteinases
-
Okada Y, Watanabe S, Nakanishi I, et al. Inactivation of tissue inhibitor of metalloproteinases by neutrophil elastase and other serine proteinases. FEBS Lett 1988; 229: 157-160.
-
(1988)
FEBS Lett
, vol.229
, pp. 157-160
-
-
Okada, Y.1
Watanabe, S.2
Nakanishi, I.3
-
45
-
-
0022615336
-
Elastase from polymorphonuclear leucocytes: A regulatory enzyme in immune complex disease
-
Döring G, Goldstein W, Botzenhart K, et al. Elastase from polymorphonuclear leucocytes: a regulatory enzyme in immune complex disease. Clin Exp Immunol 1986; 597-605.
-
(1986)
Clin Exp Immunol
, pp. 597-605
-
-
Döring, G.1
Goldstein, W.2
Botzenhart, K.3
-
47
-
-
0035448095
-
Leukocyte elastase: Physiological functions and role in acute lung injury
-
Lee WL, Downey GP. Leukocyte elastase: physiological functions and role in acute lung injury. Am J Respir Crit Care Med 2001; 164: 896-904.
-
(2001)
Am J Respir Crit Care Med
, vol.164
, pp. 896-904
-
-
Lee, W.L.1
Downey, G.P.2
-
48
-
-
0035218742
-
Proteases and antiproteases
-
Stockley RA. Proteases and antiproteases. Novartis Found Symp 2001; 234: 189-199.
-
(2001)
Novartis Found Symp
, vol.234
, pp. 189-199
-
-
Stockley, R.A.1
-
49
-
-
0028914085
-
Early pulmonary inflammation in infants with cystic fibrosis
-
Khan T, Wagener J, Bost T, Martinez J, Accurso F, Riches D. Early pulmonary inflammation in infants with cystic fibrosis. Am J Respir Crit Care Med 1995; 151: 1075-1082.
-
(1995)
Am J Respir Crit Care Med
, vol.151
, pp. 1075-1082
-
-
Khan, T.1
Wagener, J.2
Bost, T.3
Martinez, J.4
Accurso, F.5
Riches, D.6
-
50
-
-
18644377252
-
Elastolytic proteases. Inflammation resolution and dysregulation in chronic infective lung disease
-
Taggart CC, Greene CM, Carroll TP, O'Neill SJ, McElvaney NG. Elastolytic proteases. Inflammation resolution and dysregulation in chronic infective lung disease. Am J Respir Crit Care Med 2005; 171: 1070-1076.
-
(2005)
Am J Respir Crit Care Med
, vol.171
, pp. 1070-1076
-
-
Taggart, C.C.1
Greene, C.M.2
Carroll, T.P.3
O'Neill, S.J.4
McElvaney, N.G.5
-
51
-
-
0025374923
-
Neutrophil elastase cleaves C3bi on opsonized pseudomonas as well as CR1 on neutrophils to create a functionally important opsonin receptor mismatch
-
Tosi MF, Zakem H, Berger M. Neutrophil elastase cleaves C3bi on opsonized pseudomonas as well as CR1 on neutrophils to create a functionally important opsonin receptor mismatch. J Clin Invest 1990; 86: 300-308.
-
(1990)
J Clin Invest
, vol.86
, pp. 300-308
-
-
Tosi, M.F.1
Zakem, H.2
Berger, M.3
-
52
-
-
0021239746
-
Proteins of the cystic fibrosis respiratory tract. Fragmented immunoglobulin G opsonic antibody causing defective opsonophagocytosis
-
Fick RB, Naegel GP, Squier SU, Wood RE, Gee JBL, Reynolds HY. Proteins of the cystic fibrosis respiratory tract. Fragmented immunoglobulin G opsonic antibody causing defective opsonophagocytosis. J Clin Invest 1984; 74: 236-248.
-
(1984)
J Clin Invest
, vol.74
, pp. 236-248
-
-
Fick, R.B.1
Naegel, G.P.2
Squier, S.U.3
Wood, R.E.4
Gee, J.B.L.5
Reynolds, H.Y.6
-
53
-
-
0037630793
-
Limited proteolysis of surfactant protein D causes a loss of its calcium-dependent lectin functions
-
Griese M, Wiesener A, Lottspeich F, von Bredow C. Limited proteolysis of surfactant protein D causes a loss of its calcium-dependent lectin functions. Biochim Biophys Acta 2003; 1638: 157-163.
-
(2003)
Biochim Biophys Acta
, vol.1638
, pp. 157-163
-
-
Griese, M.1
Wiesener, A.2
Lottspeich, F.3
von Bredow, C.4
-
54
-
-
0042886951
-
Proteolysis of surfactant protein D by cystic fibrosis relevant proteases
-
von Bredow C, Wiesener A, Griese M. Proteolysis of surfactant protein D by cystic fibrosis relevant proteases. Lung 2003; 181: 79-88.
-
(2003)
Lung
, vol.181
, pp. 79-88
-
-
von Bredow, C.1
Wiesener, A.2
Griese, M.3
-
55
-
-
3042686384
-
Neutrophil serine proteinases inactivate surfactant protein D by cleaving within a conserved subregion of the carbohydrate recognition domain
-
Hirche TO, Crouch EC, Espinola M, et al. Neutrophil serine proteinases inactivate surfactant protein D by cleaving within a conserved subregion of the carbohydrate recognition domain. J Biol Chem 2004; 279: 27688-27698.
-
(2004)
J Biol Chem
, vol.279
, pp. 27688-27698
-
-
Hirche, T.O.1
Crouch, E.C.2
Espinola, M.3
-
56
-
-
3142777764
-
Degradation of pulmonary surfactant protein D by Pseudomonas aeruginosa elastase abrogates innate immune function
-
Alcorn JF, Wright JR. Degradation of pulmonary surfactant protein D by Pseudomonas aeruginosa elastase abrogates innate immune function. J Biol Chem 2004; 279: 30871-30879.
-
(2004)
J Biol Chem
, vol.279
, pp. 30871-30879
-
-
Alcorn, J.F.1
Wright, J.R.2
-
57
-
-
0346734183
-
Neutrophil serine proteinases cleave bacterial flagellin, abrogating its host response-inducing activity
-
Lopez-boado YS, Espinola M, Bahr S, Belaaouaj A. Neutrophil serine proteinases cleave bacterial flagellin, abrogating its host response-inducing activity. J Immunol 2004; 172: 509-515.
-
(2004)
J Immunol
, vol.172
, pp. 509-515
-
-
Lopez-boado, Y.S.1
Espinola, M.2
Bahr, S.3
Belaaouaj, A.4
-
58
-
-
0031599556
-
Degradation of annexin I in bronchoalveolar lavage fluid from patients with cystic fibrosis
-
Tsao F, Meyer K, Chen X, Rosenthal NS, Hu J. Degradation of annexin I in bronchoalveolar lavage fluid from patients with cystic fibrosis. Am J Respir Cell Mol Biol 1998; 18: 120-128.
-
(1998)
Am J Respir Cell Mol Biol
, vol.18
, pp. 120-128
-
-
Tsao, F.1
Meyer, K.2
Chen, X.3
Rosenthal, N.S.4
Hu, J.5
-
59
-
-
0034783941
-
Activation of progelatinase A (MMP-2) by neutrophil elastase, cathepsin G, and proteinase-3: A role for inflammatory cells in tumor invasion and angiogenesis
-
Shamamian P, Schwartz JD, Pocock BJZ, et al. Activation of progelatinase A (MMP-2) by neutrophil elastase, cathepsin G, and proteinase-3: a role for inflammatory cells in tumor invasion and angiogenesis. J Cell Physiol 2001; 189: 197-206.
-
(2001)
J Cell Physiol
, vol.189
, pp. 197-206
-
-
Shamamian, P.1
Schwartz, J.D.2
Pocock, B.J.Z.3
-
60
-
-
34247588138
-
Neutrophil elastase up-regulates cathepsin B and matrix metalloprotease-2 expression
-
Geraghty P, Rogan MP, Greene CM, et al. Neutrophil elastase up-regulates cathepsin B and matrix metalloprotease-2 expression. J Immunol 2007; 9: 5871-5878.
-
(2007)
J Immunol
, vol.9
, pp. 5871-5878
-
-
Geraghty, P.1
Rogan, M.P.2
Greene, C.M.3
-
61
-
-
0031041367
-
Activation of MMP-9 by neutrophil elastase in an in vivo model of acute lung injury
-
Ferry G, Lonchampt M, Pennel L, deNanteuil G, Canet E, Tucker GC. Activation of MMP-9 by neutrophil elastase in an in vivo model of acute lung injury. FEBS Lett 1997; 402: 111-115.
-
(1997)
FEBS Lett
, vol.402
, pp. 111-115
-
-
Ferry, G.1
Lonchampt, M.2
Pennel, L.3
deNanteuil, G.4
Canet, E.5
Tucker, G.C.6
-
62
-
-
34447522038
-
Matrix metalloprotease-9 dysregulation in lower airway secretions of cystic fibrosis patients
-
Gaggar A, Li Y, Weathington N, et al. Matrix metalloprotease-9 dysregulation in lower airway secretions of cystic fibrosis patients. Am J Physiol Lung Cell Mol Physiol 2007; 293: L96-L104.
-
(2007)
Am J Physiol Lung Cell Mol Physiol
, vol.293
-
-
Gaggar, A.1
Li, Y.2
Weathington, N.3
-
63
-
-
0036845446
-
Matrix metalloproteases in BAL fluid of patients with cystic fibrosis and their modulation by treatment with dornase alpha
-
Ratjen F, Hartog CM, Paul K, Wermelt J, Braun J. Matrix metalloproteases in BAL fluid of patients with cystic fibrosis and their modulation by treatment with dornase alpha. Thorax 2002; 57: 930-934.
-
(2002)
Thorax
, vol.57
, pp. 930-934
-
-
Ratjen, F.1
Hartog, C.M.2
Paul, K.3
Wermelt, J.4
Braun, J.5
-
64
-
-
0034650486
-
Cell surface-localized matrix metalloproteinase-9 proteolytically activates TGF-α and promotes tumor invasion and angiogenesis
-
Yu Q, Stamenkovic I. Cell surface-localized matrix metalloproteinase-9 proteolytically activates TGF-α and promotes tumor invasion and angiogenesis. Genes Dev 2000; 14: 163-176.
-
(2000)
Genes Dev
, vol.14
, pp. 163-176
-
-
Yu, Q.1
Stamenkovic, I.2
-
65
-
-
33644828187
-
A novel peptide CXCR ligand derived from extracellular matrix degradation during airway inflammation
-
Weathington NM, van Houwelingen AH, Noerager BD, et al. A novel peptide CXCR ligand derived from extracellular matrix degradation during airway inflammation. Nat Med 2006; 12: 317-323.
-
(2006)
Nat Med
, vol.12
, pp. 317-323
-
-
Weathington, N.M.1
van Houwelingen, A.H.2
Noerager, B.D.3
-
66
-
-
0025228983
-
Neutrophil elastase and cathepsin G stimulate secretion from cultured bovine airway gland serous cells
-
Sommerhoff CP, Nadel JA, Basbaum CB, Caughey GH. Neutrophil elastase and cathepsin G stimulate secretion from cultured bovine airway gland serous cells. J Clin Invest 1990; 85: 682-689.
-
(1990)
J Clin Invest
, vol.85
, pp. 682-689
-
-
Sommerhoff, C.P.1
Nadel, J.A.2
Basbaum, C.B.3
Caughey, G.H.4
-
67
-
-
0026457499
-
Mucus hypersecretion in bronchiectasis. The role of neutrophil proteases
-
Fahy JV, Schuster A, Ueki I, Boushey HA, Nadel JA. Mucus hypersecretion in bronchiectasis. The role of neutrophil proteases. Am Rev Respir Dis 1992; 146: 1430-1433.
-
(1992)
Am Rev Respir Dis
, vol.146
, pp. 1430-1433
-
-
Fahy, J.V.1
Schuster, A.2
Ueki, I.3
Boushey, H.A.4
Nadel, J.A.5
-
68
-
-
0034795821
-
Phagocyte receptors for apoptotic cells: Recognition, uptake, and consequences
-
Fadok VA, Bratton DL, Henson PM. Phagocyte receptors for apoptotic cells: recognition, uptake, and consequences. J Clin Invest 2001; 108: 957-962.
-
(2001)
J Clin Invest
, vol.108
, pp. 957-962
-
-
Fadok, V.A.1
Bratton, D.L.2
Henson, P.M.3
-
69
-
-
0034604029
-
A receptor for phosphatidylserine-specific clearance of apoptotic cells
-
Fadok VA, Bratton DL, Rose DM, Pearson A, Ezekewitz RAB, Henson PM. A receptor for phosphatidylserine-specific clearance of apoptotic cells. Nature 2000; 405: 85-90.
-
(2000)
Nature
, vol.405
, pp. 85-90
-
-
Fadok, V.A.1
Bratton, D.L.2
Rose, D.M.3
Pearson, A.4
Ezekewitz, R.A.B.5
Henson, P.M.6
-
70
-
-
0036195343
-
Elastase-mediated phosphatidylserine receptor cleavage impairs apoptotic cell clearance in cystic fibrosis and bronchiectasis
-
Vandivier RW, Fadok VA, Hoffmann PR, et al. Elastase-mediated phosphatidylserine receptor cleavage impairs apoptotic cell clearance in cystic fibrosis and bronchiectasis. J Clin Invest 2002; 109: 661-670.
-
(2002)
J Clin Invest
, vol.109
, pp. 661-670
-
-
Vandivier, R.W.1
Fadok, V.A.2
Hoffmann, P.R.3
-
71
-
-
0036143018
-
Phosphatidylserine-dependent ingestion of apoptotic cells promotes TGF-β1 secretion and the resolution of inflammation
-
Huynh MLN, Fadok VA, Henson PM. Phosphatidylserine-dependent ingestion of apoptotic cells promotes TGF-β1 secretion and the resolution of inflammation. J Clin Invest 2002; 109: 41-50.
-
(2002)
J Clin Invest
, vol.109
, pp. 41-50
-
-
Huynh, M.L.N.1
Fadok, V.A.2
Henson, P.M.3
-
72
-
-
0035929634
-
Interleukin-8 upregulation by neutrophil elastase is mediated by MyD88/ IRAK/TRAF-6 in human bronchial epithelium
-
Walsh DE, Greene CM, Carroll TP, et al. Interleukin-8 upregulation by neutrophil elastase is mediated by MyD88/ IRAK/TRAF-6 in human bronchial epithelium. J Biol Chem 2001; 276: 35494-35499.
-
(2001)
J Biol Chem
, vol.276
, pp. 35494-35499
-
-
Walsh, D.E.1
Greene, C.M.2
Carroll, T.P.3
-
74
-
-
0024459145
-
Complement receptor expression on neutrophils at an inflammatory site, the Pseudomonas-infected lung in cystic fibrosis
-
Berger M, Sorensen RU, Tosi MF, Dearborn DG, Döring G. Complement receptor expression on neutrophils at an inflammatory site, the Pseudomonas-infected lung in cystic fibrosis. J Clin Invest 1989; 84: 1302-1313.
-
(1989)
J Clin Invest
, vol.84
, pp. 1302-1313
-
-
Berger, M.1
Sorensen, R.U.2
Tosi, M.F.3
Dearborn, D.G.4
Döring, G.5
-
75
-
-
0026056106
-
Human neutrophil elastase releases a ligand-binding fragment from the 75-kDa tumor-necrosis-factor (TNF) receptor. Comparison with the proteolytic activity responsible for shedding of TNF receptors from stimulated neutrophils
-
Porteu F, Brockhaus M, Wallach D, Engelmann H, Nathan CF. Human neutrophil elastase releases a ligand-binding fragment from the 75-kDa tumor-necrosis-factor (TNF) receptor. Comparison with the proteolytic activity responsible for shedding of TNF receptors from stimulated neutrophils. J Biol Chem 1991; 266: 18846-18853.
-
(1991)
J Biol Chem
, vol.266
, pp. 18846-18853
-
-
Porteu, F.1
Brockhaus, M.2
Wallach, D.3
Engelmann, H.4
Nathan, C.F.5
-
76
-
-
0029135383
-
Specific sensitivity of CD43 to neutrophil elastase
-
Remold-O'Donnell E, Parent D. Specific sensitivity of CD43 to neutrophil elastase. Blood 1995; 86: 2395-2402.
-
(1995)
Blood
, vol.86
, pp. 2395-2402
-
-
Remold-O'Donnell, E.1
Parent, D.2
-
77
-
-
36849020586
-
Cleavage of CXCR1 on neutrophils disables bacterial killing in cystic fibrosis lung disease
-
Hartl D, Latzin P, Hordijk P, et al. Cleavage of CXCR1 on neutrophils disables bacterial killing in cystic fibrosis lung disease. Nat Med 2007; 13: 1423-1430.
-
(2007)
Nat Med
, vol.13
, pp. 1423-1430
-
-
Hartl, D.1
Latzin, P.2
Hordijk, P.3
-
78
-
-
0029067051
-
Cleavage of lymphocyte surface antigens CD2, CD4 and CD8 by polymorphonuclear leukocyte elastase and cathepsin G in patients with cystic fibrosis
-
Döring G, Frank F, Boudier C, Herbert S, Fleischer B, Bellon G. Cleavage of lymphocyte surface antigens CD2, CD4 and CD8 by polymorphonuclear leukocyte elastase and cathepsin G in patients with cystic fibrosis. J Immunol 1995; 154: 4842-4850.
-
(1995)
J Immunol
, vol.154
, pp. 4842-4850
-
-
Döring, G.1
Frank, F.2
Boudier, C.3
Herbert, S.4
Fleischer, B.5
Bellon, G.6
-
79
-
-
0034669918
-
Cleavage of CD14 on human gingival fibroblasts cocultured with activated neutrophils is mediated by human leukocyte elastase resulting in down-regulation of lipopolysaccharide-induced IL-8 production
-
Nemoto E, Sugawara S, Tada H, Takada H, Shimauchi H, Horiuchi H. Cleavage of CD14 on human gingival fibroblasts cocultured with activated neutrophils is mediated by human leukocyte elastase resulting in down-regulation of lipopolysaccharide-induced IL-8 production. J Immunol 2000; 165: 5807-5813.
-
(2000)
J Immunol
, vol.165
, pp. 5807-5813
-
-
Nemoto, E.1
Sugawara, S.2
Tada, H.3
Takada, H.4
Shimauchi, H.5
Horiuchi, H.6
-
80
-
-
0032900462
-
Proteolysis of monocyte CD14 by human leukocyte elastase inhibits lipopolysaccharide-mediated cell activation
-
Le Barillec K, Si-Tahar M, Balloy V, Chignard M. Proteolysis of monocyte CD14 by human leukocyte elastase inhibits lipopolysaccharide-mediated cell activation. J Clin Invest 1999; 103: 1039-1046.
-
(1999)
J Clin Invest
, vol.103
, pp. 1039-1046
-
-
Le Barillec, K.1
Si-Tahar, M.2
Balloy, V.3
Chignard, M.4
-
81
-
-
0036359614
-
Inflammatory mediators in cystic fibrosis lung disease
-
Berger M. Inflammatory mediators in cystic fibrosis lung disease. Allergy Asthma Proc 2002; 23: 19-25.
-
(2002)
Allergy Asthma Proc
, vol.23
, pp. 19-25
-
-
Berger, M.1
-
82
-
-
0026643195
-
Interleukin-8, a chemotactic and inflammatory cytokine
-
Baggiolini M, Clark-Lewis I. Interleukin-8, a chemotactic and inflammatory cytokine. FEBS Lett 1992; 307: 97-101.
-
(1992)
FEBS Lett
, vol.307
, pp. 97-101
-
-
Baggiolini, M.1
Clark-Lewis, I.2
-
84
-
-
0033979508
-
Fractional analysis of bronchoalveolar lavage fluid cytology in cystic fibrosis patients with normal lung function
-
Ratjen F, Rietschel E, Griese M, et al. Fractional analysis of bronchoalveolar lavage fluid cytology in cystic fibrosis patients with normal lung function. Eur Respir J 2000; 15: 141-145.
-
(2000)
Eur Respir J
, vol.15
, pp. 141-145
-
-
Ratjen, F.1
Rietschel, E.2
Griese, M.3
-
85
-
-
21444461227
-
Cytokine levels in sputum of cystic fibrosis patients before and after antibiotic therapy
-
Colombo C, Costantini D, Rocchi A, et al. Cytokine levels in sputum of cystic fibrosis patients before and after antibiotic therapy. Pediatr Pulmonol 2005; 40: 15-21.
-
(2005)
Pediatr Pulmonol
, vol.40
, pp. 15-21
-
-
Colombo, C.1
Costantini, D.2
Rocchi, A.3
-
86
-
-
34548282581
-
Sputum biomarkers of inflammation in cystic fibrosis lung disease
-
Sagel SD, Chmiel JF, Konstan MW. Sputum biomarkers of inflammation in cystic fibrosis lung disease. Proc Am Thorac Soc 2007; 4: 406-417.
-
(2007)
Proc Am Thorac Soc
, vol.4
, pp. 406-417
-
-
Sagel, S.D.1
Chmiel, J.F.2
Konstan, M.W.3
-
87
-
-
38349038310
-
Induced sputum in the very young: A new key to infection and inflammation
-
Mussaffi H, Fireman EM, Mei-Zahav M, Prais D, Blau H. Induced sputum in the very young: a new key to infection and inflammation. Chest 2008; 133: 176-182.
-
(2008)
Chest
, vol.133
, pp. 176-182
-
-
Mussaffi, H.1
Fireman, E.M.2
Mei-Zahav, M.3
Prais, D.4
Blau, H.5
-
88
-
-
0034954979
-
Interlobar differences in bronchoalveolar lavage fluid from children with cystic fibrosis
-
Gutierrez JP, Grimwood K, Armstrong DS, et al. Interlobar differences in bronchoalveolar lavage fluid from children with cystic fibrosis. Eur Respir J 2001; 17: 281-286.
-
(2001)
Eur Respir J
, vol.17
, pp. 281-286
-
-
Gutierrez, J.P.1
Grimwood, K.2
Armstrong, D.S.3
-
89
-
-
38449086102
-
Bronchoalveolar lavage, sputum and exhaled clinically relevant inflammatory markers: Values in healthy adults
-
Balbi B, Pignatti P, Corradi M, et al. Bronchoalveolar lavage, sputum and exhaled clinically relevant inflammatory markers: values in healthy adults. Eur Respir J 2007; 30: 769-781.
-
(2007)
Eur Respir J
, vol.30
, pp. 769-781
-
-
Balbi, B.1
Pignatti, P.2
Corradi, M.3
-
91
-
-
34247390062
-
Association between pulmonary function and sputum biomarkers in cystic fibrosis
-
Mayer-Hamblett N, Aitken ML, Accurso FJ, et al. Association between pulmonary function and sputum biomarkers in cystic fibrosis. Am J Respir Crit Care Med 2007; 175: 822-828.
-
(2007)
Am J Respir Crit Care Med
, vol.175
, pp. 822-828
-
-
Mayer-Hamblett, N.1
Aitken, M.L.2
Accurso, F.J.3
-
92
-
-
0029010510
-
Lower airway inflammation in infants and young children with cystic fibrosis
-
Armstrong DS, Grimwood K, Carzin R, Carlin B, Olinsky A. Lower airway inflammation in infants and young children with cystic fibrosis. BMJ 1995; 310: 1571-1572.
-
(1995)
BMJ
, vol.310
, pp. 1571-1572
-
-
Armstrong, D.S.1
Grimwood, K.2
Carzin, R.3
Carlin, B.4
Olinsky, A.5
-
93
-
-
28344451370
-
Lower airway inflammation in infants with cystic fibrosis detected by newborn screening
-
Armstrong DS, Hook SM, Jamsen KM, et al. Lower airway inflammation in infants with cystic fibrosis detected by newborn screening. Pediatr Pulmonol 2005; 40: 500-510.
-
(2005)
Pediatr Pulmonol
, vol.40
, pp. 500-510
-
-
Armstrong, D.S.1
Hook, S.M.2
Jamsen, K.M.3
-
94
-
-
33846907545
-
1- Antitrypsin inhalation reduces airway inflammation in cystic fibrosis patients
-
1- Antitrypsin inhalation reduces airway inflammation in cystic fibrosis patients. Eur Respir J 2007; 29: 240-250.
-
(2007)
Eur Respir J
, vol.29
, pp. 240-250
-
-
Griese, M.1
Latzin, P.2
Kappler, M.3
-
95
-
-
33750337629
-
Update on the application of chest computed tomography scanning to cystic fibrosis
-
Tiddens HA, de Jong PA. Update on the application of chest computed tomography scanning to cystic fibrosis. Curr Opin Pulm Med 2006; 12: 433-439.
-
(2006)
Curr Opin Pulm Med
, vol.12
, pp. 433-439
-
-
Tiddens, H.A.1
de Jong, P.A.2
-
96
-
-
33747789352
-
Chest computed tomography scans should be considered as a routine investigation in cystic fibrosis
-
Tiddens HA. Chest computed tomography scans should be considered as a routine investigation in cystic fibrosis. Paediatr Respir Rev 2006; 7: 202-208.
-
(2006)
Paediatr Respir Rev
, vol.7
, pp. 202-208
-
-
Tiddens, H.A.1
-
97
-
-
0041878825
-
Cellular profiles of induced sputum in children with stable cystic fibrosis: Comparison with BAL
-
Reinhardt N, Chen CIU, Loppow D, et al. Cellular profiles of induced sputum in children with stable cystic fibrosis: comparison with BAL. Eur Respir J 2003; 22: 497-502.
-
(2003)
Eur Respir J
, vol.22
, pp. 497-502
-
-
Reinhardt, N.1
Chen, C.I.U.2
Loppow, D.3
-
100
-
-
0035991340
-
Colistin stimulates the activity of neutrophil elastase and Pseudomonas aeruginosa elastase
-
Jones A, Elphick H, Pettitt E, Everard ML, Evans GS. Colistin stimulates the activity of neutrophil elastase and Pseudomonas aeruginosa elastase. Eur Respir J 2002; 19: 1136-1141.
-
(2002)
Eur Respir J
, vol.19
, pp. 1136-1141
-
-
Jones, A.1
Elphick, H.2
Pettitt, E.3
Everard, M.L.4
Evans, G.S.5
-
101
-
-
0019965228
-
Proteolysis by neutrophils. Relative importance of cell-substrate contact and oxidative inactivation of proteinase inhibitors in vitro
-
Campbell EJ, Senior RM, McDonald JA, Cox DL. Proteolysis by neutrophils. Relative importance of cell-substrate contact and oxidative inactivation of proteinase inhibitors in vitro. J Clin Invest 1982; 70: 845-852.
-
(1982)
J Clin Invest
, vol.70
, pp. 845-852
-
-
Campbell, E.J.1
Senior, R.M.2
McDonald, J.A.3
Cox, D.L.4
-
102
-
-
22744446014
-
Current synthetic inhibitors of human neutrophil elastase in 2005
-
Ohbayashi H. Current synthetic inhibitors of human neutrophil elastase in 2005. Expert Opin Ther Pat 2005; 15: 759-771.
-
(2005)
Expert Opin Ther Pat
, vol.15
, pp. 759-771
-
-
Ohbayashi, H.1
-
103
-
-
0028865394
-
Cell surface-bound elastase and cathepsin G on human neutrophils: A novel, non-oxidative mechanism by which neutrophils focus and preserve catalytic activity of serine proteinases
-
Owen CA, Campbell MA, Sannes PL, Boukedes SS, Campbell EJ. Cell surface-bound elastase and cathepsin G on human neutrophils: a novel, non-oxidative mechanism by which neutrophils focus and preserve catalytic activity of serine proteinases. J Cell Biol 1995; 131: 775-789.
-
(1995)
J Cell Biol
, vol.131
, pp. 775-789
-
-
Owen, C.A.1
Campbell, M.A.2
Sannes, P.L.3
Boukedes, S.S.4
Campbell, E.J.5
-
104
-
-
0033056463
-
The cell biology of leukocyte-mediated proteolysis
-
Owen CA, Campbell EJ. The cell biology of leukocyte-mediated proteolysis. J Leukoc Biol 1999; 65: 137-150.
-
(1999)
J Leukoc Biol
, vol.65
, pp. 137-150
-
-
Owen, C.A.1
Campbell, E.J.2
-
105
-
-
28244456240
-
Proteinases and oxidants as targets in the treatment of chronic obstructive pulmonary disease
-
Owen CA. Proteinases and oxidants as targets in the treatment of chronic obstructive pulmonary disease. Proc Am Thorac Soc 2005; 2: 373-385.
-
(2005)
Proc Am Thorac Soc
, vol.2
, pp. 373-385
-
-
Owen, C.A.1
-
107
-
-
33745941917
-
EPI-hNE4, a proteolysis-resistant inhibitor of human neutrophil elastase and potential anti-inflammatory drug for treating cystic fibrosis
-
Attucci S, Gauthier A, Korkmaz B, et al. EPI-hNE4, a proteolysis-resistant inhibitor of human neutrophil elastase and potential anti-inflammatory drug for treating cystic fibrosis. J Pharmacol Exp Ther 2006; 318: 803-809.
-
(2006)
J Pharmacol Exp Ther
, vol.318
, pp. 803-809
-
-
Attucci, S.1
Gauthier, A.2
Korkmaz, B.3
-
108
-
-
0037794398
-
Characteristics of EPI-hNE4 aerosol: A new elastase inhibitor for treatment of cystic fibrosis
-
Grimbert D, Vecellio L, Delepine P, et al. Characteristics of EPI-hNE4 aerosol: a new elastase inhibitor for treatment of cystic fibrosis. J Aerosol Med 2003; 16: 121-129.
-
(2003)
J Aerosol Med
, vol.16
, pp. 121-129
-
-
Grimbert, D.1
Vecellio, L.2
Delepine, P.3
-
109
-
-
0036008396
-
Protection against acute lung injury by intravenous or intratracheal pretreatment with EPI-HNE-4, a new potent neutrophil elastase inhibitor
-
Delacourt C, Herigault S, Delclaux C, et al. Protection against acute lung injury by intravenous or intratracheal pretreatment with EPI-HNE-4, a new potent neutrophil elastase inhibitor. Am J Respir CellMol Biol 2002; 26: 290-297.
-
(2002)
Am J Respir CellMol Biol
, vol.26
, pp. 290-297
-
-
Delacourt, C.1
Herigault, S.2
Delclaux, C.3
-
110
-
-
0026769518
-
Intravenous recombinant secretory leukoprotease inhibitor augments antineutrophil elastase defense
-
Birrer P, McElvaney NG, Gillissen A, et al. Intravenous recombinant secretory leukoprotease inhibitor augments antineutrophil elastase defense. J Appl Physiol 1992; 73: 317-323.
-
(1992)
J Appl Physiol
, vol.73
, pp. 317-323
-
-
Birrer, P.1
McElvaney, N.G.2
Gillissen, A.3
-
111
-
-
0023605968
-
-
Tetley TD, Smith SF, Burton GH, Winning AJ, Cooke NT, Guz A. Effects of cigarette smoking and drugs on respiratory tract proteases and antiproteases. Eur J Respir Dis Suppl 1987; 153: 93-102.
-
Tetley TD, Smith SF, Burton GH, Winning AJ, Cooke NT, Guz A. Effects of cigarette smoking and drugs on respiratory tract proteases and antiproteases. Eur J Respir Dis Suppl 1987; 153: 93-102.
-
-
-
-
112
-
-
0027495712
-
Pharmacokinetics of recombinant secretory leukoprotease inhibitor aerosolized to normals and individuals with cystic fibrosis
-
McElvaney NG, Doujaiji B, Moan MJ, Burnham MR, Wu MC, Crystal RG. Pharmacokinetics of recombinant secretory leukoprotease inhibitor aerosolized to normals and individuals with cystic fibrosis. Am Rev Respir Dis 1993; 148: 1056-1060.
-
(1993)
Am Rev Respir Dis
, vol.148
, pp. 1056-1060
-
-
McElvaney, N.G.1
Doujaiji, B.2
Moan, M.J.3
Burnham, M.R.4
Wu, M.C.5
Crystal, R.G.6
-
113
-
-
0026493036
-
Isolation of elafin and elastase-specific inhibitor (ESI) from bronchial secretions. Evidence of sequence homology and immunological cross-reactivity
-
Sallenave JM, Marsden MD, Ryle AP. Isolation of elafin and elastase-specific inhibitor (ESI) from bronchial secretions. Evidence of sequence homology and immunological cross-reactivity. Biol Chem Hoppe Seyler 1992; 373: 27-33.
-
(1992)
Biol Chem Hoppe Seyler
, vol.373
, pp. 27-33
-
-
Sallenave, J.M.1
Marsden, M.D.2
Ryle, A.P.3
-
114
-
-
0034581627
-
The role of secretory leukocyte proteinase inhibitor and elafin (elastase-specific inhibitor/skinderived antileukoprotease) as alarm antiproteinases in inflammatory lung disease
-
Sallenave JM. The role of secretory leukocyte proteinase inhibitor and elafin (elastase-specific inhibitor/skinderived antileukoprotease) as alarm antiproteinases in inflammatory lung disease. Respir Res 2000; 1: 87-92.
-
(2000)
Respir Res
, vol.1
, pp. 87-92
-
-
Sallenave, J.M.1
-
115
-
-
0028675419
-
Regulation of secretory leukocyte proteinase inhibitor (SLPI) and elastase-specific inhibitor (ESI/ elafin) in human airway epithelial cells by cytokines and neutrophilic enzymes
-
Sallenave JM, Shulmann J, Crossley J, Jordana M, Gauldie J. Regulation of secretory leukocyte proteinase inhibitor (SLPI) and elastase-specific inhibitor (ESI/ elafin) in human airway epithelial cells by cytokines and neutrophilic enzymes. Am J Respir Cell Mol Biol 1994; 11: 733-741.
-
(1994)
Am J Respir Cell Mol Biol
, vol.11
, pp. 733-741
-
-
Sallenave, J.M.1
Shulmann, J.2
Crossley, J.3
Jordana, M.4
Gauldie, J.5
-
116
-
-
0028341330
-
Modulation of secretory leukoprotease inhibitor gene expression in human bronchial epithelial cells by phorbol ester
-
Maruyama M, Hay JG, Yoshimura K, Chu CS, Crystal RG. Modulation of secretory leukoprotease inhibitor gene expression in human bronchial epithelial cells by phorbol ester. J Clin Invest 1994; 94: 368-375.
-
(1994)
J Clin Invest
, vol.94
, pp. 368-375
-
-
Maruyama, M.1
Hay, J.G.2
Yoshimura, K.3
Chu, C.S.4
Crystal, R.G.5
-
117
-
-
29144439305
-
Secretory leucoprotease inhibitor binds to NF-κB binding sites in monocytes and inhibits p65 binding
-
Taggart CC, Cryan SA, Weldon S, et al. Secretory leucoprotease inhibitor binds to NF-κB binding sites in monocytes and inhibits p65 binding. J Exp Med 2005; 202: 1659-1668.
-
(2005)
J Exp Med
, vol.202
, pp. 1659-1668
-
-
Taggart, C.C.1
Cryan, S.A.2
Weldon, S.3
-
118
-
-
34247138728
-
The role of secretory leucoprotease inhibitor in the resolution of inflammatory responses
-
Weldon S, McGarry N, Taggart CC, McElvaney NG. The role of secretory leucoprotease inhibitor in the resolution of inflammatory responses. Biochem Soc Trans 2007; 35: 273-276.
-
(2007)
Biochem Soc Trans
, vol.35
, pp. 273-276
-
-
Weldon, S.1
McGarry, N.2
Taggart, C.C.3
McElvaney, N.G.4
-
119
-
-
13444287817
-
Aerosol treatment with MNEI suppresses bacterial proliferation in a model of chronic Pseudomonas aeruginosa lung infection
-
Woods DE, Cantin A, Cooley J, Kenney DM, Remold-O'Donnell E. Aerosol treatment with MNEI suppresses bacterial proliferation in a model of chronic Pseudomonas aeruginosa lung infection. Pediatr Pulmonol 2005; 39: 141-149.
-
(2005)
Pediatr Pulmonol
, vol.39
, pp. 141-149
-
-
Woods, D.E.1
Cantin, A.2
Cooley, J.3
Kenney, D.M.4
Remold-O'Donnell, E.5
-
120
-
-
0034760267
-
Inhibition of human neutrophil elastase by erythromycin and flurythromycin, two macrolide antibiotics
-
Gorrini M, Lupi A, Viglio S, et al. Inhibition of human neutrophil elastase by erythromycin and flurythromycin, two macrolide antibiotics. Am J Respir Cell Mol Biol 2001; 25: 492-499.
-
(2001)
Am J Respir Cell Mol Biol
, vol.25
, pp. 492-499
-
-
Gorrini, M.1
Lupi, A.2
Viglio, S.3
-
121
-
-
0022244747
-
1- Antitrypsin
-
1- Antitrypsin. J Med 1985; 16: 23-99.
-
(1985)
J Med
, vol.16
, pp. 23-99
-
-
Berninger, R.W.1
-
122
-
-
12344305212
-
Potential role of inhibitors of neutrophil elastase in treating diseases of the airway
-
Chughtai B, O'Riordan TG. Potential role of inhibitors of neutrophil elastase in treating diseases of the airway. J Aerosol Med 2004; 17: 289-298.
-
(2004)
J Aerosol Med
, vol.17
, pp. 289-298
-
-
Chughtai, B.1
O'Riordan, T.G.2
-
123
-
-
0034003241
-
Technology evaluation: Transgenic alpha-1-antitrypsin (AAT), PPL Therapeutics
-
Tebbutt SJ. Technology evaluation: transgenic alpha-1-antitrypsin (AAT), PPL Therapeutics. Curr Opin Mol Ther 2000; 2: 199-204.
-
(2000)
Curr Opin Mol Ther
, vol.2
, pp. 199-204
-
-
Tebbutt, S.J.1
-
124
-
-
21244492343
-
A pilot study comparing the purity, functionality and isoform composition of alpha-1-proteinase inhibitor (human) products
-
Cowden DI, Fisher GE, Weeks RL. A pilot study comparing the purity, functionality and isoform composition of alpha-1-proteinase inhibitor (human) products. Curr Med Res Opin 2005; 21: 877-883.
-
(2005)
Curr Med Res Opin
, vol.21
, pp. 877-883
-
-
Cowden, D.I.1
Fisher, G.E.2
Weeks, R.L.3
-
125
-
-
33745065087
-
Recombinant human alpha-1 proteinase inhibitor: Towards therapeutic use
-
Karnaukhova E, Ophir Y, Golding B. Recombinant human alpha-1 proteinase inhibitor: towards therapeutic use. Amino Acids 2006; 30: 317-332.
-
(2006)
Amino Acids
, vol.30
, pp. 317-332
-
-
Karnaukhova, E.1
Ophir, Y.2
Golding, B.3
-
126
-
-
27344436813
-
1-protease inhibitor for treatment of α-antitrypsin deficiency
-
1-protease inhibitor for treatment of α-antitrypsin deficiency. Ann Pharmacother 2005; 39: 1861-1869.
-
(2005)
Ann Pharmacother
, vol.39
, pp. 1861-1869
-
-
Louie, S.G.1
Sclar, D.A.2
Gill, M.A.3
-
128
-
-
0023148995
-
Replacement therapy for alpha 1-antitrypsin deficiency associated with emphysema
-
Wewers MD, Casolaro MA, Sellers SE, et al. Replacement therapy for alpha 1-antitrypsin deficiency associated with emphysema. N Engl J Med 1987; 316: 1055-1062.
-
(1987)
N Engl J Med
, vol.316
, pp. 1055-1062
-
-
Wewers, M.D.1
Casolaro, M.A.2
Sellers, S.E.3
-
129
-
-
0023107891
-
Comparison of alpha-1-antitrypsin levels and antineutrophil elastase capacity of blood and lung in a patient with the alpha-1-antitrypsin phenotype null-null before and during alpha-1-antitrypsin augmentation therapy
-
Wewers MD, Casolaro MA, Crystal RG. Comparison of alpha-1-antitrypsin levels and antineutrophil elastase capacity of blood and lung in a patient with the alpha-1-antitrypsin phenotype null-null before and during alpha-1-antitrypsin augmentation therapy. Am Rev Respir Dis 1987; 135: 539-543.
-
(1987)
Am Rev Respir Dis
, vol.135
, pp. 539-543
-
-
Wewers, M.D.1
Casolaro, M.A.2
Crystal, R.G.3
-
130
-
-
0026474443
-
Modulation of airway inflammation in cystic fibrosis
-
McElvaney N, Nakamura H, Birrer P, et al. Modulation of airway inflammation in cystic fibrosis. J Clin Invest 1992; 90: 1296-1301.
-
(1992)
J Clin Invest
, vol.90
, pp. 1296-1301
-
-
McElvaney, N.1
Nakamura, H.2
Birrer, P.3
-
131
-
-
14744276106
-
High level expression of active human alpha-1-antitrypsin in the milk of transgenic sheep
-
Wright G, Carver A, Cottom D, et al. High level expression of active human alpha-1-antitrypsin in the milk of transgenic sheep. Biotechnology (N Y) 1991; 9: 830-834.
-
(1991)
Biotechnology (N Y)
, vol.9
, pp. 830-834
-
-
Wright, G.1
Carver, A.2
Cottom, D.3
-
132
-
-
0025360692
-
Strategies for aerosol therapy of alpha 1-antitrypsin deficiency by the aerosol route
-
Hubbard RC, Crystal RG. Strategies for aerosol therapy of alpha 1-antitrypsin deficiency by the aerosol route. Lung 1990; 168: Suppl., 565-578.
-
(1990)
Lung
, vol.168
, Issue.SUPPL.
, pp. 565-578
-
-
Hubbard, R.C.1
Crystal, R.G.2
-
135
-
-
0031045338
-
The intrapulmonary half-life and safety of aerosolized alpha1-protease inhibitor in normal volunteers
-
Vogelmeier C, Kirlath I, Warrington S, Banik N, Ulbrich E, Dubois RM. The intrapulmonary half-life and safety of aerosolized alpha1-protease inhibitor in normal volunteers. Am J Respir Crit Care Med 1997; 155: 536-541.
-
(1997)
Am J Respir Crit Care Med
, vol.155
, pp. 536-541
-
-
Vogelmeier, C.1
Kirlath, I.2
Warrington, S.3
Banik, N.4
Ulbrich, E.5
Dubois, R.M.6
-
138
-
-
0035686310
-
1-protease inhibitor in cystic fibrosis does not affect surfactant convertase and surface activity
-
1-protease inhibitor in cystic fibrosis does not affect surfactant convertase and surface activity. Pulm Pharmacol Ther 2001; 14: 461-467.
-
(2001)
Pulm Pharmacol Ther
, vol.14
, pp. 461-467
-
-
Griese, M.1
von Bredow, C.2
Birrer, P.3
Schams, A.4
-
140
-
-
0142043977
-
Pathophysiology and management of pulmonary infections in cystic fibrosis
-
Gibson R, Burns JL, Ramsey BW. Pathophysiology and management of pulmonary infections in cystic fibrosis. Am J Respir Crit Care Med 2003; 168: 918-951.
-
(2003)
Am J Respir Crit Care Med
, vol.168
, pp. 918-951
-
-
Gibson, R.1
Burns, J.L.2
Ramsey, B.W.3
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