Potential role of inhibitors of neutrophil elastase in treating diseases of the airway

Journal of Aerosol Medicine: Deposition, Clearance, and Effects in the Lung

Volumn 17, Issue 4, 2004, Pages 289-298

  Chughtai, Bilal ^a   O'Riordan, Thomas G ^a  

^a STONY BROOK UNIVERSITY   (United States)

Author keywords

Aerosolized medications; Mucous hypersecretion; Protease inhibitors; Serpins

Indexed keywords

[4 (4 BROMOPHENYLSULFONYLCARBAMOYL)BENZOYL]VALYLPROLINE N (2 METHYL 1 TRIFLUOROACETYLPROPYL)AMIDE; AE 3763; ALPHA 1 ANTITRYPSIN; BRONCHODILATING AGENT; CE 1037; CORTICOSTEROID; DX 890; ELAFIN; FK 706; GW 311616; LEUKOCYTE ELASTASE; LEUKOCYTE ELASTASE INHIBITOR; MIDESTEINE; N [1 (1,3 BENZODIOXOL 5 YL)BUTYL] 3,3 DIETHYL 2 [4 [(4 METHYL 1 PIPERAZINYL)CARBONYL]PHENOXY] 4 OXO 1 AZETIDINECARBOXAMIDE; N [4 [(4 CHLOROPHENYLSULFONYL)AMINOCARBONYL]BENZOYL]VALYLPROLYLVALYL TRIFLUOROMETHYL KETONE; ONO 6818; PROTEIN EPI HNE 1; RECOMBINANT PROTEIN; SECRETORY LEUKOCYTE PROTEINASE INHIBITOR; SERINE PROTEINASE INHIBITOR; SIVELESTAT; TEI 8362; UNCLASSIFIED DRUG; ZD 0892; ZD 8321;

AEROSOL; ASTHMA; CHRONIC OBSTRUCTIVE LUNG DISEASE; CYSTIC FIBROSIS; DOSE RESPONSE; DRUG DELIVERY SYSTEM; DRUG EFFICACY; DRUG HALF LIFE; DRUG PURIFICATION; DRUG SAFETY; GENE THERAPY; HUMAN; MUCUS SECRETION; NEBULIZATION; NEUTROPHIL; NONHUMAN; PATHOGENESIS; PROTEIN DEGRADATION; PROTEIN FUNCTION; RESPIRATORY TRACT DISEASE; REVIEW;

ADMINISTRATION, INHALATION; AEROSOLS; ALPHA 1-ANTITRYPSIN; CLINICAL TRIALS; GENE THERAPY; HUMANS; LEUKOCYTE ELASTASE; LUNG DISEASES; PULMONARY EMPHYSEMA; RECOMBINANT PROTEINS; RESPIRATORY DISTRESS SYNDROME, ADULT; SERINE PROTEINASE INHIBITORS;

EID: 12344305212     PISSN: 08942684     EISSN: None     Source Type: Journal    
DOI: 10.1089/jam.2004.17.289     Document Type: Review

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