Misassembled mutant ΔF508 CFTR in the distal secretory pathway alters cellular lipid trafficking

Journal of Cell Science

Volumn 120, Issue 3, 2007, Pages 447-455

  Gentzsch, Martina ^a   Choudhury, Amit ^b   Chang, Xiu Bao ^b   Pagano, Richard E ^b   Riordan, John R ^a  

^a UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^b MAYO GRADUATE SCHOOL   (United States)

Author keywords

CFTR; Cholesterol; Cystic fibrosis; Glycosphingolipids; Lipid trafficking

Indexed keywords

ABC TRANSPORTER; CHOLESTEROL; CHOLESTEROL ESTER; GLYCOSPHINGOLIPID; LIPID; MULTIDRUG RESISTANCE PROTEIN 1; MUTANT PROTEIN; RAB PROTEIN; TRANSMEMBRANE CONDUCTANCE REGULATOR;

ANIMAL CELL; ARTICLE; CELL COMPARTMENTALIZATION; CELL STRUCTURE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; ENDOPLASMIC RETICULUM; ENDOSOME; ESTERIFICATION; GENE OVEREXPRESSION; HOMEOSTASIS; INTRACELLULAR SPACE; LOW TEMPERATURE; NONHUMAN; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN EXPRESSION; PROTEIN FUNCTION; QUALITY CONTROL; SECRETORY VESICLE; ANIMAL; CELL LINE; CELL MEMBRANE; CHO CELL; CRICETULUS; ENDOCYTOSIS; GENE DELETION; GENETIC TRANSFECTION; GENETICS; HAMSTER; METABOLISM; MUTATION; PHYSIOLOGY; SITE DIRECTED MUTAGENESIS;

ANIMALS; CELL LINE; CELL MEMBRANE; CHO CELLS; CHOLESTEROL; CRICETINAE; CRICETULUS; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR; ENDOCYTOSIS; ENDOSOMES; GENE DELETION; GLYCOSPHINGOLIPIDS; MUTAGENESIS, SITE-DIRECTED; MUTATION; TRANSFECTION;

EID: 33847357783     PISSN: 00219533     EISSN: None     Source Type: Journal    
DOI: 10.1242/jcs.03350     Document Type: Article

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