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Volumn 301, Issue 1, 2009, Pages 71-81

CD4+CD25+ regulatory T cells in human lupus erythematosus

Author keywords

Autoimmunity; CD4+CD25+ cells; FoxP3; Lupus erythematosus; Regulatory T cells

Indexed keywords

CORTICOSTEROID; CYCLOPHOSPHAMIDE; IMMUNOSUPPRESSIVE AGENT; RITUXIMAB; TRANSCRIPTION FACTOR FOXP3;

EID: 58149151240     PISSN: 03403696     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00403-008-0891-9     Document Type: Review
Times cited : (87)

References (76)
  • 1
    • 33749520621 scopus 로고    scopus 로고
    • Regulatory T cells in patients with systemic lupus erythematosus
    • 10.1016/j.jaut.2006.06.005
    • B Alvarado-Sanchez B Hernandez-Castro D Portales-Perez 2006 Regulatory T cells in patients with systemic lupus erythematosus J Autoimmun 27 110 118 10.1016/j.jaut.2006.06.005
    • (2006) J Autoimmun , vol.27 , pp. 110-118
    • Alvarado-Sanchez, B.1    Hernandez-Castro, B.2    Portales-Perez, D.3
  • 2
    • 41549153318 scopus 로고    scopus 로고
    • CD4+CD25+ regulatory T cells (TREG) in systemic lupus erythematosus (SLE) patients: The possible influence of treatment with corticosteroids
    • 10.1016/j.clim.2007.12.010
    • NA Azab IH Bassyouni Y Emad 2008 CD4+CD25+ regulatory T cells (TREG) in systemic lupus erythematosus (SLE) patients: the possible influence of treatment with corticosteroids Clin Immunol 127 151 157 10.1016/j.clim.2007.12.010
    • (2008) Clin Immunol , vol.127 , pp. 151-157
    • Azab, N.A.1    Bassyouni, I.H.2    Emad, Y.3
  • 4
    • 34547800213 scopus 로고    scopus 로고
    • Measurement of natural (CD4+CD25 high) and inducible (CD4+IL-10+) regulatory T cells in patients with systemic lupus erythematosus
    • 10.1177/0961203307080226
    • S Barath M Aleksza T Tarr 2007 Measurement of natural (CD4+CD25 high) and inducible (CD4+IL-10+) regulatory T cells in patients with systemic lupus erythematosus Lupus 16 489 496 10.1177/0961203307080226
    • (2007) Lupus , vol.16 , pp. 489-496
    • Barath, S.1    Aleksza, M.2    Tarr, T.3
  • 5
    • 39049139330 scopus 로고    scopus 로고
    • The severity of systemic lupus erythematosus negatively correlates with the increasing number of CD4+CD25(high)FoxP3+regulatory T cells during repeated plasmapheresis treatments of patients
    • 10.1080/08916930701610028
    • S Barath P Soltesz E Kiss 2007 The severity of systemic lupus erythematosus negatively correlates with the increasing number of CD4+CD25(high)FoxP3+regulatory T cells during repeated plasmapheresis treatments of patients Autoimmunity 40 521 528 10.1080/08916930701610028
    • (2007) Autoimmunity , vol.40 , pp. 521-528
    • Barath, S.1    Soltesz, P.2    Kiss, E.3
  • 7
    • 0035167967 scopus 로고    scopus 로고
    • The immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) is caused by mutations of FOXP3
    • 10.1038/83713
    • CL Bennett J Christie F Ramsdell 2001 The immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) is caused by mutations of FOXP3 Nat Genet 27 20 21 10.1038/83713
    • (2001) Nat Genet , vol.27 , pp. 20-21
    • Bennett, C.L.1    Christie, J.2    Ramsdell, F.3
  • 8
    • 13544265305 scopus 로고    scopus 로고
    • Cutaneous T-cell lymphoma: Malignant proliferation of T-regulatory cells
    • 10.1182/blood-2004-06-2181
    • CL Berger R Tigelaar J Cohen 2005 Cutaneous T-cell lymphoma: malignant proliferation of T-regulatory cells Blood 105 1640 1647 10.1182/blood-2004-06- 2181
    • (2005) Blood , vol.105 , pp. 1640-1647
    • Berger, C.L.1    Tigelaar, R.2    Cohen, J.3
  • 10
    • 45849145442 scopus 로고    scopus 로고
    • Quantitative and qualitative deficiencies of regulatory T cells in patients with systemic lupus erythematosus (SLE)
    • 10.1093/intimm/dxn044
    • M Bonelli A Savitskaya K von Dalwigk 2008 Quantitative and qualitative deficiencies of regulatory T cells in patients with systemic lupus erythematosus (SLE) Int Immunol 20 861 868 10.1093/intimm/dxn044
    • (2008) Int Immunol , vol.20 , pp. 861-868
    • Bonelli, M.1    Savitskaya, A.2    Von Dalwigk, K.3
  • 11
    • 1942456867 scopus 로고    scopus 로고
    • CD4+CD25+ regulatory T-cell deficiency in patients with hepatitis C-mixed cryoglobulinemia vasculitis
    • 10.1182/blood-2003-07-2598
    • O Boyer D Saadoun J Abriol 2004 CD4+CD25+ regulatory T-cell deficiency in patients with hepatitis C-mixed cryoglobulinemia vasculitis Blood 103 3428 3430 10.1182/blood-2003-07-2598
    • (2004) Blood , vol.103 , pp. 3428-3430
    • Boyer, O.1    Saadoun, D.2    Abriol, J.3
  • 12
    • 0035162560 scopus 로고    scopus 로고
    • Disruption of a new forkhead/winged-helix protein, scurfin, results in the fatal lymphoproliferative disorder of the scurfy mouse
    • 10.1038/83784
    • ME Brunkow EW Jeffery KA Hjerrild 2001 Disruption of a new forkhead/winged-helix protein, scurfin, results in the fatal lymphoproliferative disorder of the scurfy mouse Nat Genet 27 68 73 10.1038/83784
    • (2001) Nat Genet , vol.27 , pp. 68-73
    • Brunkow, M.E.1    Jeffery, E.W.2    Hjerrild, K.A.3
  • 13
    • 33745522182 scopus 로고    scopus 로고
    • FOXP3 identifies regulatory CD25bright CD4+T cells in rheumatic joints
    • 10.1111/j.1365-3083.2006.001755.x
    • D Cao O Borjesson P Larsson 2006 FOXP3 identifies regulatory CD25bright CD4+T cells in rheumatic joints Scand J Immunol 63 444 452 10.1111/j.1365-3083. 2006.001755.x
    • (2006) Scand J Immunol , vol.63 , pp. 444-452
    • Cao, D.1    Borjesson, O.2    Larsson, P.3
  • 14
    • 0037261145 scopus 로고    scopus 로고
    • Isolation and functional characterization of regulatory CD25brightCD4+T cells from the target organ of patients with rheumatoid arthritis
    • 10.1002/immu.200390024
    • D Cao V Malmstrom C Baecher-Allan 2003 Isolation and functional characterization of regulatory CD25brightCD4+T cells from the target organ of patients with rheumatoid arthritis Eur J Immunol 33 215 223 10.1002/immu. 200390024
    • (2003) Eur J Immunol , vol.33 , pp. 215-223
    • Cao, D.1    Malmstrom, V.2    Baecher-Allan, C.3
  • 15
    • 15244361536 scopus 로고    scopus 로고
    • CD25brightCD4+ regulatory T cells are enriched in inflamed joints of patients with chronic rheumatic disease
    • 10.1186/ar1192
    • D Cao R van Vollenhoven L Klareskog C Trollmo V Malmstrom 2004 CD25brightCD4+ regulatory T cells are enriched in inflamed joints of patients with chronic rheumatic disease Arthritis Res Ther 6 R335 R346 10.1186/ar1192
    • (2004) Arthritis Res Ther , vol.6
    • Cao, D.1    Van Vollenhoven, R.2    Klareskog, L.3    Trollmo, C.4    Malmstrom, V.5
  • 16
    • 34447529156 scopus 로고    scopus 로고
    • Effect of steroids on the frequency of regulatory T cells and expression of FOXP3 in a patient with systemic lupus erythematosus: A two-year follow-up
    • 10.1177/0961203307077990
    • AM Cepika I Marinic J Morovic-Vergles D Soldo-Juresa A Gagro 2007 Effect of steroids on the frequency of regulatory T cells and expression of FOXP3 in a patient with systemic lupus erythematosus: a two-year follow-up Lupus 16 374 377 10.1177/0961203307077990
    • (2007) Lupus , vol.16 , pp. 374-377
    • Cepika, A.M.1    Marinic, I.2    Morovic-Vergles, J.3    Soldo-Juresa, D.4    Gagro, A.5
  • 17
    • 27644433355 scopus 로고    scopus 로고
    • Role of regulatory T cells in human diseases
    • quiz 960. doi: 10.1016/j.jaci.2005.08.047
    • Chatila TA (2005) Role of regulatory T cells in human diseases. J Allergy Clin Immunol 116:949-959. quiz 960. doi: 10.1016/j.jaci.2005.08.047
    • (2005) J Allergy Clin Immunol , vol.116 , pp. 949-959
    • Chatila, T.A.1
  • 18
    • 33748297521 scopus 로고    scopus 로고
    • The role of CD4+CD25 high regulatory T cells in the physiopathogeny of graft-versus-host disease
    • 10.1016/j.coi.2006.07.007
    • JL Cohen O Boyer 2006 The role of CD4+CD25 high regulatory T cells in the physiopathogeny of graft-versus-host disease Curr Opin Immunol 18 580 585 10.1016/j.coi.2006.07.007
    • (2006) Curr Opin Immunol , vol.18 , pp. 580-585
    • Cohen, J.L.1    Boyer, O.2
  • 20
    • 44849089131 scopus 로고    scopus 로고
    • Human regulatory T cells and autoimmunity
    • 10.1002/eji.200738104
    • CM Costantino CM Baecher-Allan DA Hafler 2008 Human regulatory T cells and autoimmunity Eur J Immunol 38 921 924 10.1002/eji.200738104
    • (2008) Eur J Immunol , vol.38 , pp. 921-924
    • Costantino, C.M.1    Baecher-Allan, C.M.2    Hafler, D.A.3
  • 21
    • 0242403301 scopus 로고    scopus 로고
    • Quantification of regulatory T cells in patients with systemic lupus erythematosus
    • 10.1016/S0896-8411(03)00121-5
    • JC Crispin A Martinez J Alcocer-Varela 2003 Quantification of regulatory T cells in patients with systemic lupus erythematosus J Autoimmun 21 273 276 10.1016/S0896-8411(03)00121-5
    • (2003) J Autoimmun , vol.21 , pp. 273-276
    • Crispin, J.C.1    Martinez, A.2    Alcocer-Varela, J.3
  • 22
    • 33645059454 scopus 로고    scopus 로고
    • Imbalance of regulatory T cells in human autoimmune diseases
    • 10.1111/j.1365-2567.2005.02317.x
    • C Dejaco C Duftner B Grubeck-Loebenstein M Schirmer 2006 Imbalance of regulatory T cells in human autoimmune diseases Immunology 117 289 300 10.1111/j.1365-2567.2005.02317.x
    • (2006) Immunology , vol.117 , pp. 289-300
    • Dejaco, C.1    Duftner, C.2    Grubeck-Loebenstein, B.3    Schirmer, M.4
  • 23
    • 0035806244 scopus 로고    scopus 로고
    • Ex vivo isolation and characterization of CD4(+)CD25(+) T cells with regulatory properties from human blood
    • 10.1084/jem.193.11.1303
    • D Dieckmann H Plottner S Berchtold T Berger G Schuler 2001 Ex vivo isolation and characterization of CD4(+)CD25(+) T cells with regulatory properties from human blood J Exp Med 193 1303 1310 10.1084/jem.193.11.1303
    • (2001) J Exp Med , vol.193 , pp. 1303-1310
    • Dieckmann, D.1    Plottner, H.2    Berchtold, S.3    Berger, T.4    Schuler, G.5
  • 24
    • 33846410763 scopus 로고    scopus 로고
    • Diminished CD4+CD25+ T-lymphocytes in peripheral blood of patients with systemic lupus erythematosus
    • A Fathy RW Mohamed GA Tawfik AS Omar 2005 Diminished CD4+CD25+ T-lymphocytes in peripheral blood of patients with systemic lupus erythematosus Egypt J Immunol 12 25 31
    • (2005) Egypt J Immunol , vol.12 , pp. 25-31
    • Fathy, A.1    Mohamed, R.W.2    Tawfik, G.A.3    Omar, A.S.4
  • 25
    • 0037385330 scopus 로고    scopus 로고
    • Foxp3 programs the development and function of CD4+CD25+ regulatory T cells
    • 10.1038/ni904
    • JD Fontenot MA Gavin AY Rudensky 2003 Foxp3 programs the development and function of CD4+CD25+ regulatory T cells Nat Immunol 4 330 336 10.1038/ni904
    • (2003) Nat Immunol , vol.4 , pp. 330-336
    • Fontenot, J.D.1    Gavin, M.A.2    Rudensky, A.Y.3
  • 26
    • 34447500365 scopus 로고    scopus 로고
    • Low number of regulatory T cells in skin lesions of patients with cutaneous lupus erythematosus
    • 10.1002/art.22699
    • B Franz B Fritzsching A Riehl 2007 Low number of regulatory T cells in skin lesions of patients with cutaneous lupus erythematosus Arthritis Rheum 56 1910 1920 10.1002/art.22699
    • (2007) Arthritis Rheum , vol.56 , pp. 1910-1920
    • Franz, B.1    Fritzsching, B.2    Riehl, A.3
  • 27
    • 13544271161 scopus 로고    scopus 로고
    • Cutting edge: Contact-mediated suppression by CD4+CD25+ regulatory cells involves a granzyme B-dependent, perforin-independent mechanism
    • DC Gondek LF Lu SA Quezada S Sakaguchi RJ Noelle 2005 Cutting edge: contact-mediated suppression by CD4+CD25+ regulatory cells involves a granzyme B-dependent, perforin-independent mechanism J Immunol 174 1783 1786
    • (2005) J Immunol , vol.174 , pp. 1783-1786
    • Gondek, D.C.1    Lu, L.F.2    Quezada, S.A.3    Sakaguchi, S.4    Noelle, R.J.5
  • 28
    • 27944499757 scopus 로고    scopus 로고
    • Reduced suppressive effect of CD4+CD25 high regulatory T cells on the T cell immune response against myelin oligodendrocyte glycoprotein in patients with multiple sclerosis
    • 10.1002/eji.200526065
    • J Haas A Hug A Viehover 2005 Reduced suppressive effect of CD4+CD25 high regulatory T cells on the T cell immune response against myelin oligodendrocyte glycoprotein in patients with multiple sclerosis Eur J Immunol 35 3343 3352 10.1002/eji.200526065
    • (2005) Eur J Immunol , vol.35 , pp. 3343-3352
    • Haas, J.1    Hug, A.2    Viehover, A.3
  • 29
    • 0347785480 scopus 로고    scopus 로고
    • Control of regulatory T cell development by the transcription factor Foxp3
    • 10.1126/science.1079490
    • S Hori T Nomura S Sakaguchi 2003 Control of regulatory T cell development by the transcription factor Foxp3 Science 299 1057 1061 10.1126/science.1079490
    • (2003) Science , vol.299 , pp. 1057-1061
    • Hori, S.1    Nomura, T.2    Sakaguchi, S.3
  • 30
    • 0035806290 scopus 로고    scopus 로고
    • Identification and functional characterization of human CD4(+)CD25(+) T cells with regulatory properties isolated from peripheral blood
    • 10.1084/jem.193.11.1285
    • H Jonuleit E Schmitt M Stassen 2001 Identification and functional characterization of human CD4(+)CD25(+) T cells with regulatory properties isolated from peripheral blood J Exp Med 193 1285 1294 10.1084/jem.193.11.1285
    • (2001) J Exp Med , vol.193 , pp. 1285-1294
    • Jonuleit, H.1    Schmitt, E.2    Stassen, M.3
  • 31
    • 0037385314 scopus 로고    scopus 로고
    • An essential role for Scurfin in CD4+CD25+ T regulatory cells
    • 10.1038/ni909
    • R Khattri T Cox SA Yasayko F Ramsdell 2003 An essential role for Scurfin in CD4+CD25+ T regulatory cells Nat Immunol 4 337 342 10.1038/ni909
    • (2003) Nat Immunol , vol.4 , pp. 337-342
    • Khattri, R.1    Cox, T.2    Yasayko, S.A.3    Ramsdell, F.4
  • 32
    • 33646593910 scopus 로고    scopus 로고
    • Paucity of FOXP3+ cells in skin and peripheral blood distinguishes Sezary syndrome from other cutaneous T-cell lymphomas
    • 10.1038/sj.leu.2404182
    • CD Klemke B Fritzsching B Franz 2006 Paucity of FOXP3+ cells in skin and peripheral blood distinguishes Sezary syndrome from other cutaneous T-cell lymphomas Leukemia 20 1123 1129 10.1038/sj.leu.2404182
    • (2006) Leukemia , vol.20 , pp. 1123-1129
    • Klemke, C.D.1    Fritzsching, B.2    Franz, B.3
  • 33
    • 2442628376 scopus 로고    scopus 로고
    • Defective suppressor function of human CD4+CD25+ regulatory T cells in autoimmune polyglandular syndrome type II
    • 10.1084/jem.20032158
    • MA Kriegel T Lohmann C Gabler 2004 Defective suppressor function of human CD4+CD25+ regulatory T cells in autoimmune polyglandular syndrome type II J Exp Med 199 1285 1291 10.1084/jem.20032158
    • (2004) J Exp Med , vol.199 , pp. 1285-1291
    • Kriegel, M.A.1    Lohmann, T.2    Gabler, C.3
  • 34
    • 44849084204 scopus 로고    scopus 로고
    • Pathogenesis of cutaneous lupus erythematosus
    • 10.1177/0961203308090019
    • A Kuhn M Bijl 2008 Pathogenesis of cutaneous lupus erythematosus Lupus 17 389 393 10.1177/0961203308090019
    • (2008) Lupus , vol.17 , pp. 389-393
    • Kuhn, A.1    Bijl, M.2
  • 35
    • 0036141438 scopus 로고    scopus 로고
    • Multiple immuno-regulatory defects in type-1 diabetes
    • A Kukreja G Cost J Marker 2002 Multiple immuno-regulatory defects in type-1 diabetes J Clin Invest 109 131 140
    • (2002) J Clin Invest , vol.109 , pp. 131-140
    • Kukreja, A.1    Cost, G.2    Marker, J.3
  • 36
    • 44849125410 scopus 로고    scopus 로고
    • Altered frequency and migration capacity of CD4+CD25+ regulatory T cells in systemic lupus erythematosus
    • 10.1093/rheumatology/ken108
    • HY Lee YK Hong HJ Yun 2008 Altered frequency and migration capacity of CD4+CD25+ regulatory T cells in systemic lupus erythematosus Rheumatol (Oxf) 47 789 794 10.1093/rheumatology/ken108
    • (2008) Rheumatol (Oxf) , vol.47 , pp. 789-794
    • Lee, H.Y.1    Hong, Y.K.2    Yun, H.J.3
  • 37
    • 33645051462 scopus 로고    scopus 로고
    • Inverse correlation between CD4+ regulatory T-cell population and autoantibody levels in paediatric patients with systemic lupus erythematosus
    • 10.1111/j.1365-2567.2005.02306.x
    • JH Lee LC Wang YT Lin 2006 Inverse correlation between CD4+ regulatory T-cell population and autoantibody levels in paediatric patients with systemic lupus erythematosus Immunology 117 280 286 10.1111/j.1365-2567.2005.02306.x
    • (2006) Immunology , vol.117 , pp. 280-286
    • Lee, J.H.1    Wang, L.C.2    Lin, Y.T.3
  • 38
    • 25444497719 scopus 로고    scopus 로고
    • Cutting edge: Direct suppression of B cells by CD4+CD25+ regulatory T cells
    • HW Lim P Hillsamer AH Banham CH Kim 2005 Cutting edge: direct suppression of B cells by CD4+CD25+ regulatory T cells J Immunol 175 4180 4183
    • (2005) J Immunol , vol.175 , pp. 4180-4183
    • Lim, H.W.1    Hillsamer, P.2    Banham, A.H.3    Kim, C.H.4
  • 39
    • 36349010693 scopus 로고    scopus 로고
    • The quantitative analysis of peripheral blood FOXP3-expressing T cells in systemic lupus erythematosus and rheumatoid arthritis patients
    • 10.1111/j.1365-2362.2007.01882.x
    • SC Lin KH Chen CH Lin 2007 The quantitative analysis of peripheral blood FOXP3-expressing T cells in systemic lupus erythematosus and rheumatoid arthritis patients Eur J Clin Invest 37 987 996 10.1111/j.1365-2362.2007.01882.x
    • (2007) Eur J Clin Invest , vol.37 , pp. 987-996
    • Lin, S.C.1    Chen, K.H.2    Lin, C.H.3
  • 40
    • 12144249838 scopus 로고    scopus 로고
    • Defective suppressor function in CD4(+)CD25(+) T-cells from patients with type 1 diabetes
    • 10.2337/diabetes.54.1.92
    • S Lindley CM Dayan A Bishop 2005 Defective suppressor function in CD4(+)CD25(+) T-cells from patients with type 1 diabetes Diabetes 54 92 99 10.2337/diabetes.54.1.92
    • (2005) Diabetes , vol.54 , pp. 92-99
    • Lindley, S.1    Dayan, C.M.2    Bishop, A.3
  • 41
    • 36048942044 scopus 로고    scopus 로고
    • Dendritic cells and T cells in the regulation of cutaneous immunity
    • 10.1016/j.yadr.2007.07.014
    • K Loser S Beissert 2007 Dendritic cells and T cells in the regulation of cutaneous immunity Adv Dermatol 23 307 333 10.1016/j.yadr.2007.07.014
    • (2007) Adv Dermatol , vol.23 , pp. 307-333
    • Loser, K.1    Beissert, S.2
  • 42
    • 20944435842 scopus 로고    scopus 로고
    • An important role of CD80/CD86-CTLA-4 signaling during photocarcinogenesis in mice
    • K Loser A Scherer MB Krummen 2005 An important role of CD80/CD86-CTLA-4 signaling during photocarcinogenesis in mice J Immunol 174 5298 5305
    • (2005) J Immunol , vol.174 , pp. 5298-5305
    • Loser, K.1    Scherer, A.2    Krummen, M.B.3
  • 43
    • 34848898991 scopus 로고    scopus 로고
    • Reduced number and function of CD4+CD25 highFoxP3+ regulatory T cells in patients with systemic lupus erythematosus
    • EY Lyssuk AV Torgashina SK Soloviev EL Nassonov SN Bykovskaia 2007 Reduced number and function of CD4+CD25 highFoxP3+ regulatory T cells in patients with systemic lupus erythematosus Adv Exp Med Biol 601 113 119
    • (2007) Adv Exp Med Biol , vol.601 , pp. 113-119
    • Lyssuk, E.Y.1    Torgashina, A.V.2    Soloviev, S.K.3    Nassonov, E.L.4    Bykovskaia, S.N.5
  • 44
    • 33645119478 scopus 로고    scopus 로고
    • Decrease of regulatory T cells in patients with systemic lupus erythematosus
    • 10.1136/ard.2005.044974
    • S Mellor-Pita MJ Citores R Castejon 2006 Decrease of regulatory T cells in patients with systemic lupus erythematosus Ann Rheum Dis 65 553 554 10.1136/ard.2005.044974
    • (2006) Ann Rheum Dis , vol.65 , pp. 553-554
    • Mellor-Pita, S.1    Citores, M.J.2    Castejon, R.3
  • 45
    • 29144516273 scopus 로고    scopus 로고
    • Global natural regulatory T cell depletion in active systemic lupus erythematosus
    • M Miyara Z Amoura C Parizot 2005 Global natural regulatory T cell depletion in active systemic lupus erythematosus J Immunol 175 8392 8400
    • (2005) J Immunol , vol.175 , pp. 8392-8400
    • Miyara, M.1    Amoura, Z.2    Parizot, C.3
  • 46
    • 33344457856 scopus 로고    scopus 로고
    • The immune paradox of sarcoidosis and regulatory T cells
    • 10.1084/jem.20050648
    • M Miyara Z Amoura C Parizot 2006 The immune paradox of sarcoidosis and regulatory T cells J Exp Med 203 359 370 10.1084/jem.20050648
    • (2006) J Exp Med , vol.203 , pp. 359-370
    • Miyara, M.1    Amoura, Z.2    Parizot, C.3
  • 47
    • 17244378876 scopus 로고    scopus 로고
    • MRL/Mp CD4+, CD25-T cells show reduced sensitivity to suppression by CD4+, CD25+ regulatory T cells in vitro: A novel defect of T cell regulation in systemic lupus erythematosus
    • 10.1002/art.20976
    • CR Monk M Spachidou F Rovis 2005 MRL/Mp CD4+, CD25-T cells show reduced sensitivity to suppression by CD4+, CD25+ regulatory T cells in vitro: a novel defect of T cell regulation in systemic lupus erythematosus Arthritis Rheum 52 1180 1184 10.1002/art.20976
    • (2005) Arthritis Rheum , vol.52 , pp. 1180-1184
    • Monk, C.R.1    Spachidou, M.2    Rovis, F.3
  • 48
    • 1942531991 scopus 로고    scopus 로고
    • T regulatory cells in atopic dermatitis and subversion of their activity by superantigens
    • 10.1016/j.jaci.2004.01.772
    • LS Ou E Goleva C Hall DY Leung 2004 T regulatory cells in atopic dermatitis and subversion of their activity by superantigens J Allergy Clin Immunol 113 756 763 10.1016/j.jaci.2004.01.772
    • (2004) J Allergy Clin Immunol , vol.113 , pp. 756-763
    • Ou, L.S.1    Goleva, E.2    Hall, C.3    Leung, D.Y.4
  • 49
    • 0035421654 scopus 로고    scopus 로고
    • Cutting edge: Control of CD8+ T cell activation by CD4+CD25+ immunoregulatory cells
    • CA Piccirillo EM Shevach 2001 Cutting edge: control of CD8+ T cell activation by CD4+CD25+ immunoregulatory cells J Immunol 167 1137 1140
    • (2001) J Immunol , vol.167 , pp. 1137-1140
    • Piccirillo, C.A.1    Shevach, E.M.2
  • 50
    • 0037236815 scopus 로고    scopus 로고
    • Regulatory T cells: Mediating compromises between host and parasite
    • 10.1038/ni0103-10
    • S Sakaguchi 2003 Regulatory T cells: mediating compromises between host and parasite Nat Immunol 4 10 11 10.1038/ni0103-10
    • (2003) Nat Immunol , vol.4 , pp. 10-11
    • Sakaguchi, S.1
  • 51
    • 2442484053 scopus 로고    scopus 로고
    • Naturally arising CD4+ regulatory T cells for immunologic self-tolerance and negative control of immune responses
    • 10.1146/annurev.immunol.21.120601.141122
    • S Sakaguchi 2004 Naturally arising CD4+ regulatory T cells for immunologic self-tolerance and negative control of immune responses Annu Rev Immunol 22 531 562 10.1146/annurev.immunol.21.120601.141122
    • (2004) Annu Rev Immunol , vol.22 , pp. 531-562
    • Sakaguchi, S.1
  • 52
    • 44849129837 scopus 로고    scopus 로고
    • Regulatory T cells in the past and for the future
    • 10.1002/eji.200890012
    • S Sakaguchi 2008 Regulatory T cells in the past and for the future Eur J Immunol 38 901 937 10.1002/eji.200890012
    • (2008) Eur J Immunol , vol.38 , pp. 901-937
    • Sakaguchi, S.1
  • 53
    • 22244462396 scopus 로고    scopus 로고
    • Regulatory T cells in immunologic self-tolerance and autoimmune disease
    • 10.1080/08830180590934976
    • S Sakaguchi N Sakaguchi 2005 Regulatory T cells in immunologic self-tolerance and autoimmune disease Int Rev Immunol 24 211 226 10.1080/08830180590934976
    • (2005) Int Rev Immunol , vol.24 , pp. 211-226
    • Sakaguchi, S.1    Sakaguchi, N.2
  • 54
    • 0029150110 scopus 로고
    • Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases
    • S Sakaguchi N Sakaguchi M Asano M Itoh M Toda 1995 Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases J Immunol 155 1151 1164
    • (1995) J Immunol , vol.155 , pp. 1151-1164
    • Sakaguchi, S.1    Sakaguchi, N.2    Asano, M.3    Itoh, M.4    Toda, M.5
  • 55
    • 0035180065 scopus 로고    scopus 로고
    • Immunologic tolerance maintained by CD25+CD4+ regulatory T cells: Their common role in controlling autoimmunity, tumor immunity, and transplantation tolerance
    • 10.1034/j.1600-065X.2001.1820102.x
    • S Sakaguchi N Sakaguchi J Shimizu 2001 Immunologic tolerance maintained by CD25+CD4+ regulatory T cells: their common role in controlling autoimmunity, tumor immunity, and transplantation tolerance Immunol Rev 182 18 32 10.1034/j.1600-065X.2001.1820102.x
    • (2001) Immunol Rev , vol.182 , pp. 18-32
    • Sakaguchi, S.1    Sakaguchi, N.2    Shimizu, J.3
  • 56
    • 33947118656 scopus 로고    scopus 로고
    • Increased expression of the FoxP3 functional marker of regulatory T cells following B cell depletion with rituximab in patients with lupus nephritis
    • 10.1016/j.clim.2006.12.006
    • PP Sfikakis VL Souliotis KG Fragiadaki 2007 Increased expression of the FoxP3 functional marker of regulatory T cells following B cell depletion with rituximab in patients with lupus nephritis Clin Immunol 123 66 73 10.1016/j.clim.2006.12.006
    • (2007) Clin Immunol , vol.123 , pp. 66-73
    • Sfikakis, P.P.1    Souliotis, V.L.2    Fragiadaki, K.G.3
  • 57
    • 0034084162 scopus 로고    scopus 로고
    • Regulatory T cells in autoimmmunity
    • 10.1146/annurev.immunol.18.1.423
    • EM Shevach 2000 Regulatory T cells in autoimmmunity Annu Rev Immunol 18 423 449 10.1146/annurev.immunol.18.1.423
    • (2000) Annu Rev Immunol , vol.18 , pp. 423-449
    • Shevach, E.M.1
  • 58
    • 0036597371 scopus 로고    scopus 로고
    • CD4+CD25+ suppressor T cells: More questions than answers
    • EM Shevach 2002 CD4+CD25+ suppressor T cells: more questions than answers Nat Rev Immunol 2 389 400
    • (2002) Nat Rev Immunol , vol.2 , pp. 389-400
    • Shevach, E.M.1
  • 59
    • 31144468294 scopus 로고    scopus 로고
    • CD4+CD25+ T regulatory cells suppress NK cell-mediated immunotherapy of cancer
    • MJ Smyth MW Teng J Swann 2006 CD4+CD25+ T regulatory cells suppress NK cell-mediated immunotherapy of cancer J Immunol 176 1582 1587
    • (2006) J Immunol , vol.176 , pp. 1582-1587
    • Smyth, M.J.1    Teng, M.W.2    Swann, J.3
  • 60
    • 33750358659 scopus 로고    scopus 로고
    • Enrichment of CD4+CD25 high T cell population in patients with systemic lupus erythematosus treated with glucocorticoids
    • 10.1136/ard.2005.049924
    • A Suarez P Lopez J Gomez C Gutierrez 2006 Enrichment of CD4+CD25 high T cell population in patients with systemic lupus erythematosus treated with glucocorticoids Ann Rheum Dis 65 1512 1517 10.1136/ard.2005.049924
    • (2006) Ann Rheum Dis , vol.65 , pp. 1512-1517
    • Suarez, A.1    Lopez, P.2    Gomez, J.3    Gutierrez, C.4
  • 61
    • 10844222790 scopus 로고    scopus 로고
    • Dysfunctional blood and target tissue CD4+CD25 high regulatory T cells in psoriasis: Mechanism underlying unrestrained pathogenic effector T cell proliferation
    • H Sugiyama R Gyulai E Toichi 2005 Dysfunctional blood and target tissue CD4+CD25 high regulatory T cells in psoriasis: mechanism underlying unrestrained pathogenic effector T cell proliferation J Immunol 174 164 173
    • (2005) J Immunol , vol.174 , pp. 164-173
    • Sugiyama, H.1    Gyulai, R.2    Toichi, E.3
  • 62
    • 2442637772 scopus 로고    scopus 로고
    • Cutting edge: IL-2 is critically required for the in vitro activation of CD4+CD25+ T cell suppressor function
    • AM Thornton EE Donovan CA Piccirillo EM Shevach 2004 Cutting edge: IL-2 is critically required for the in vitro activation of CD4+CD25+ T cell suppressor function J Immunol 172 6519 6523
    • (2004) J Immunol , vol.172 , pp. 6519-6523
    • Thornton, A.M.1    Donovan, E.E.2    Piccirillo, C.A.3    Shevach, E.M.4
  • 63
    • 0031821875 scopus 로고    scopus 로고
    • CD4+CD25+ immunoregulatory T cells suppress polyclonal T cell activation in vitro by inhibiting interleukin 2 production
    • 10.1084/jem.188.2.287
    • AM Thornton EM Shevach 1998 CD4+CD25+ immunoregulatory T cells suppress polyclonal T cell activation in vitro by inhibiting interleukin 2 production J Exp Med 188 287 296 10.1084/jem.188.2.287
    • (1998) J Exp Med , vol.188 , pp. 287-296
    • Thornton, A.M.1    Shevach, E.M.2
  • 64
    • 0033985780 scopus 로고    scopus 로고
    • Suppressor effector function of CD4+CD25+ immunoregulatory T cells is antigen nonspecific
    • AM Thornton EM Shevach 2000 Suppressor effector function of CD4+CD25+ immunoregulatory T cells is antigen nonspecific J Immunol 164 183 190
    • (2000) J Immunol , vol.164 , pp. 183-190
    • Thornton, A.M.1    Shevach, E.M.2
  • 65
    • 4043089285 scopus 로고    scopus 로고
    • CD4+CD25+ T regulatory cells inhibit cytotoxic activity of T CD8+ and NK lymphocytes in the direct cell-to-cell interaction
    • 10.1016/j.clim.2004.04.003
    • P Trzonkowski E Szmit J Mysliwska A Dobyszuk A Mysliwski 2004 CD4+CD25+ T regulatory cells inhibit cytotoxic activity of T CD8+ and NK lymphocytes in the direct cell-to-cell interaction Clin Immunol 112 258 267 10.1016/j.clim.2004. 04.003
    • (2004) Clin Immunol , vol.112 , pp. 258-267
    • Trzonkowski, P.1    Szmit, E.2    Mysliwska, J.3    Dobyszuk, A.4    Mysliwski, A.5
  • 66
    • 33646370647 scopus 로고    scopus 로고
    • TNF downmodulates the function of human CD4+CD25high T-regulatory cells
    • 10.1182/blood-2005-11-4567
    • X Valencia G Stephens R Goldbach-Mansky 2006 TNF downmodulates the function of human CD4+CD25high T-regulatory cells Blood 108 253 261 10.1182/blood-2005-11-4567
    • (2006) Blood , vol.108 , pp. 253-261
    • Valencia, X.1    Stephens, G.2    Goldbach-Mansky, R.3
  • 67
    • 33846900430 scopus 로고    scopus 로고
    • Deficient CD4+CD25 high T regulatory cell function in patients with active systemic lupus erythematosus
    • X Valencia C Yarboro G Illei PE Lipsky 2007 Deficient CD4+CD25 high T regulatory cell function in patients with active systemic lupus erythematosus J Immunol 178 2579 2588
    • (2007) J Immunol , vol.178 , pp. 2579-2588
    • Valencia, X.1    Yarboro, C.2    Illei, G.3    Lipsky, P.E.4
  • 68
    • 33845869839 scopus 로고    scopus 로고
    • Treatment with rituximab affects both the cellular and the humoral arm of the immune system in patients with SLE
    • 10.1016/j.clim.2006.08.016
    • T Vallerskog I Gunnarsson M Widhe 2007 Treatment with rituximab affects both the cellular and the humoral arm of the immune system in patients with SLE Clin Immunol 122 62 74 10.1016/j.clim.2006.08.016
    • (2007) Clin Immunol , vol.122 , pp. 62-74
    • Vallerskog, T.1    Gunnarsson, I.2    Widhe, M.3
  • 69
    • 43249122144 scopus 로고    scopus 로고
    • Quantitative and qualitative normal regulatory T cells are not capable of inducing suppression in SLE patients due to T-cell resistance
    • 10.1177/0961203307088307
    • MI Vargas-Rojas JC Crispin Y Richaud-Patin J Alcocer-Varela 2008 Quantitative and qualitative normal regulatory T cells are not capable of inducing suppression in SLE patients due to T-cell resistance Lupus 17 289 294 10.1177/0961203307088307
    • (2008) Lupus , vol.17 , pp. 289-294
    • Vargas-Rojas, M.I.1    Crispin, J.C.2    Richaud-Patin, Y.3    Alcocer-Varela, J.4
  • 70
    • 1842732224 scopus 로고    scopus 로고
    • Loss of functional suppression by CD4+CD25+ regulatory T cells in patients with multiple sclerosis
    • 10.1084/jem.20031579
    • V Viglietta C Baecher-Allan HL Weiner DA Hafler 2004 Loss of functional suppression by CD4+CD25+ regulatory T cells in patients with multiple sclerosis J Exp Med 199 971 979 10.1084/jem.20031579
    • (2004) J Exp Med , vol.199 , pp. 971-979
    • Viglietta, V.1    Baecher-Allan, C.2    Weiner, H.L.3    Hafler, D.A.4
  • 71
    • 1642497640 scopus 로고    scopus 로고
    • Tumor-specific human CD4+ regulatory T cells and their ligands: Implications for immunotherapy
    • 10.1016/S1074-7613(03)00359-5
    • HY Wang DA Lee G Peng 2004 Tumor-specific human CD4+ regulatory T cells and their ligands: implications for immunotherapy Immunity 20 107 118 10.1016/S1074-7613(03)00359-5
    • (2004) Immunity , vol.20 , pp. 107-118
    • Wang, H.Y.1    Lee, D.A.2    Peng, G.3
  • 72
    • 0035163909 scopus 로고    scopus 로고
    • X-linked neonatal diabetes mellitus, enteropathy and endocrinopathy syndrome is the human equivalent of mouse scurfy
    • 10.1038/83707
    • RS Wildin F Ramsdell J Peake 2001 X-linked neonatal diabetes mellitus, enteropathy and endocrinopathy syndrome is the human equivalent of mouse scurfy Nat Genet 27 18 20 10.1038/83707
    • (2001) Nat Genet , vol.27 , pp. 18-20
    • Wildin, R.S.1    Ramsdell, F.2    Peake, J.3
  • 73
    • 0036284229 scopus 로고    scopus 로고
    • Characterization of human CD25+CD4+ T cells in thymus, cord and adult blood
    • 10.1046/j.1365-2567.2002.01412.x
    • K Wing A Ekmark H Karlsson A Rudin E Suri-Payer 2002 Characterization of human CD25+CD4+ T cells in thymus, cord and adult blood Immunology 106 190 199 10.1046/j.1365-2567.2002.01412.x
    • (2002) Immunology , vol.106 , pp. 190-199
    • Wing, K.1    Ekmark, A.2    Karlsson, H.3    Rudin, A.4    Suri-Payer, E.5
  • 74
    • 1842681797 scopus 로고    scopus 로고
    • A deficiency of CD4+CD25+ T cells permits the development of spontaneous lupus-like disease in mice, and can be reversed by induction of mucosal tolerance to histone peptide autoantigen
    • 10.1191/0961203303lu1002oa
    • HY Wu NA Staines 2004 A deficiency of CD4+CD25+ T cells permits the development of spontaneous lupus-like disease in mice, and can be reversed by induction of mucosal tolerance to histone peptide autoantigen Lupus 13 192 200 10.1191/0961203303lu1002oa
    • (2004) Lupus , vol.13 , pp. 192-200
    • Wu, H.Y.1    Staines, N.A.2
  • 75
    • 40549128298 scopus 로고    scopus 로고
    • Dysfunctional CD4+, CD25+ regulatory T cells in untreated active systemic lupus erythematosus secondary to interferon-alpha-producing antigen-presenting cells
    • 10.1002/art.23268
    • B Yan S Ye G Chen 2008 Dysfunctional CD4+, CD25+ regulatory T cells in untreated active systemic lupus erythematosus secondary to interferon-alpha- producing antigen-presenting cells Arthritis Rheum 58 801 812 10.1002/art.23268
    • (2008) Arthritis Rheum , vol.58 , pp. 801-812
    • Yan, B.1    Ye, S.2    Chen, G.3
  • 76
    • 47249083906 scopus 로고    scopus 로고
    • Reduction of forkhead box P3 levels in CD4(+)CD25(high) T cells in patients with new-onset systemic lupus erythematosus
    • B Zhang X Zhang Tang Tang L Zhu Y Liu 2008 Reduction of forkhead box P3 levels in CD4(+)CD25(high) T cells in patients with new-onset systemic lupus erythematosus Clin Exp Immunol 153 182 187
    • (2008) Clin Exp Immunol , vol.153 , pp. 182-187
    • Zhang, B.1    Zhang, X.2    Tang, T.3    Zhu, L.4    Liu, Y.5


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