Fibrinogen-elongated γ chain inhibits thrombin-induced platelet response, hindering the interaction with different receptors

Journal of Biological Chemistry

Volumn 283, Issue 44, 2008, Pages 30193-30204

  Lancellotti, Stefano ^a   Rutella, Sergio ^a   De Filippis, Vincenzo ^b   Pozzi, Nicola ^b   Rocca, Bianca ^a   De Cristofaro, Raimondo ^a  

^a CATHOLIC UNIVERSITY   (Italy)

^b UNIVERSITY OF PADOVA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATED RECEPTORS; ALTERNATIVE SPLICING; COMBINED MECHANISMS; DO-MAINS; HIGH AFFINITIES; IN-VIVO; INSERTION SEQUENCES; PLATELET AGGREGATIONS; PLATELET RESPONSES; SPECTROFLUORIMETRIC; THROMBIN BINDINGS;

AMINES; AMINO ACIDS; FLOW INTERACTIONS; ORGANIC ACIDS; PLATELETS;

BLOOD SUBSTITUTES;

C PEPTIDE; DEXTRO PHENYL PIPECOLYL ARGINYL 4 NITROANILIDE; FIBRINOGEN; GLYCOPROTEIN IB ALPHA; PEPTIDE DERIVATIVE; PROTEINASE ACTIVATED RECEPTOR 1; PROTEINASE ACTIVATED RECEPTOR 4; THROMBIN; THROMBOCYTE RECEPTOR; UNCLASSIFIED DRUG;

ALLOSTERISM; ARTICLE; BINDING AFFINITY; IC 50; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN INTERACTION; SOLID; SPECTROFLUOROMETRY; THROMBOCYTE AGGREGATION; THROMBOCYTE FUNCTION;

BINDING SITES; BINDING, COMPETITIVE; BLOOD PLATELETS; FIBRINOGEN; HUMANS; HYDROLYSIS; KINETICS; PEPTIDES; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; RECEPTOR, PAR-1; RECEPTORS, THROMBIN; SPECTROMETRY, FLUORESCENCE; THROMBIN;

EID: 57649183329     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M803659200     Document Type: Article

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