메뉴 건너뛰기




Volumn 139, Issue 3, 2007, Pages 494-503

Fibrinogen γ′ chain carboxy terminal peptide selectively inhibits the intrinsic coagulation pathway

Author keywords

Animal model; Anticoagulants; Blood coagulation; Factor VIII; Thrombin; Thrombosis

Indexed keywords

BLOOD CLOTTING FACTOR 8; FIBRINOGEN; THROMBIN; ANTICOAGULANT AGENT; FIBRINOPEPTIDES GAMMA; PEPTIDE FRAGMENT; UNCLASSIFIED DRUG;

EID: 34848841484     PISSN: 00071048     EISSN: 13652141     Source Type: Journal    
DOI: 10.1111/j.1365-2141.2007.06825.x     Document Type: Article
Times cited : (35)

References (64)
  • 2
    • 0026575221 scopus 로고
    • Selection of single-stranded DNA molecules that bind and inhibit human thrombin
    • Bock, L.C., Griffin, L.C., Latham, J.A., Vermaas, E.H. Toole, J.J. (1992) Selection of single-stranded DNA molecules that bind and inhibit human thrombin. Nature, 355, 564 566.
    • (1992) Nature , vol.355 , pp. 564-566
    • Bock, L.C.1    Griffin, L.C.2    Latham, J.A.3    Vermaas, E.H.4    Toole, J.J.5
  • 5
    • 0025369391 scopus 로고
    • Effects of red blood cell concentration on hemostasis and thrombus formation in a primate model
    • Cadroy, Y. Hanson, S.R. (1990) Effects of red blood cell concentration on hemostasis and thrombus formation in a primate model. Blood, 75, 2185 2193.
    • (1990) Blood , vol.75 , pp. 2185-2193
    • Cadroy, Y.1    Hanson, S.R.2
  • 6
    • 0024459459 scopus 로고
    • RGDV peptide selectivity inhibits platelet dependent thrombus formation in vivo
    • Cadroy, Y., Houghton, R.A. Hanson, S.R. (1989) RGDV peptide selectivity inhibits platelet dependent thrombus formation in vivo. Journal of Clinical Investigation, 84, 939 944.
    • (1989) Journal of Clinical Investigation , vol.84 , pp. 939-944
    • Cadroy, Y.1    Houghton, R.A.2    Hanson, S.R.3
  • 9
    • 0021184750 scopus 로고
    • γ and γ′ chains of human fibrinogen are produced by alternative mRNA processing
    • Chung, D.W. Davie, E.W. (1984) γ and γ′ chains of human fibrinogen are produced by alternative mRNA processing. Biochemistry, 23, 4232 4236.
    • (1984) Biochemistry , vol.23 , pp. 4232-4236
    • Chung, D.W.1    Davie, E.W.2
  • 12
    • 0041344493 scopus 로고    scopus 로고
    • Interaction of the 268-282 region of glycoprotein Ibα with the heparin-binding site of thrombin inhibits the enzyme activation of factor VIII
    • De Cristofaro, R. De Filippis, V. (2003) Interaction of the 268-282 region of glycoprotein Ibα with the heparin-binding site of thrombin inhibits the enzyme activation of factor VIII. Biochemical Journal, 373, 593 601.
    • (2003) Biochemical Journal , vol.373 , pp. 593-601
    • De Cristofaro, R.1    De Filippis, V.2
  • 13
    • 0034635224 scopus 로고    scopus 로고
    • The Asp(272)-Glu(282) region of platelet glycoprotein Ibα interacts with the heparin-binding site of α-thrombin and protects the enzyme from the heparin-catalyzed inhibition by antithrombin III
    • De Cristofaro, R., De Candia, E., Rutella, S. Weitz, J.I. (2000) The Asp(272)-Glu(282) region of platelet glycoprotein Ibα interacts with the heparin-binding site of α-thrombin and protects the enzyme from the heparin-catalyzed inhibition by antithrombin III. Journal of Biological Chemistry, 275, 3887 3895.
    • (2000) Journal of Biological Chemistry , vol.275 , pp. 3887-3895
    • De Cristofaro, R.1    De Candia, E.2    Rutella, S.3    Weitz, J.I.4
  • 14
    • 0038157329 scopus 로고    scopus 로고
    • Crystal structure of the GpIbα-thrombin complex essential for platelet aggregation
    • Dumas, J.J., Kumar, R., Seehra, J., Somers, W.S. Mosyak, L. (2003) Crystal structure of the GpIbα-thrombin complex essential for platelet aggregation. Science, 301, 222 226.
    • (2003) Science , vol.301 , pp. 222-226
    • Dumas, J.J.1    Kumar, R.2    Seehra, J.3    Somers, W.S.4    Mosyak, L.5
  • 15
    • 0029935853 scopus 로고    scopus 로고
    • Involvement of thrombin anion-binding exosites 1 and 2 in the activation of factor V and factor VIII
    • Esmon, C.T. Lollar, P. (1996) Involvement of thrombin anion-binding exosites 1 and 2 in the activation of factor V and factor VIII. Journal of Biological Chemistry, 271, 13882 13887.
    • (1996) Journal of Biological Chemistry , vol.271 , pp. 13882-13887
    • Esmon, C.T.1    Lollar, P.2
  • 17
    • 0030611710 scopus 로고    scopus 로고
    • Resistance of γa/γ′ fibrin clots to fibrinolysis
    • Falls, L.A. Farrell, D.H. (1997) Resistance of γA/γ′ fibrin clots to fibrinolysis. Journal of Biological Chemistry, 272, 14251 14256.
    • (1997) Journal of Biological Chemistry , vol.272 , pp. 14251-14256
    • Falls, L.A.1    Farrell, D.H.2
  • 18
    • 3242730967 scopus 로고    scopus 로고
    • Pathophysiologic roles of the fibrinogen γ chain
    • Farrell, D.H. (2004) Pathophysiologic roles of the fibrinogen γ chain. Current Opinion in Hematology, 11, 151 155.
    • (2004) Current Opinion in Hematology , vol.11 , pp. 151-155
    • Farrell, D.H.1
  • 20
    • 0021744551 scopus 로고
    • Structure of the human γ-fibrinogen gene: Alternate mRNA splicing near the 3' end of the gene produces γa and γb forms of γ-fibrinogen
    • Fornace, A.J., Cummings, D.E., Comeau, C.M., Kant, J.A. Crabtree, G.R. (1984) Structure of the human γ-fibrinogen gene: alternate mRNA splicing near the 3' end of the gene produces γA and γB forms of γ-fibrinogen. Journal of Biological Chemistry, 259, 12826 12830.
    • (1984) Journal of Biological Chemistry , vol.259 , pp. 12826-12830
    • Fornace, A.J.1    Cummings, D.E.2    Comeau, C.M.3    Kant, J.A.4    Crabtree, G.R.5
  • 22
    • 0025874052 scopus 로고
    • Factor XI activation in a revised model of blood coagulation
    • Gailani, D. Broze, Jr., G.J. (1991) Factor XI activation in a revised model of blood coagulation. Science, 253, 909 912.
    • (1991) Science , vol.253 , pp. 909-912
    • Gailani, D.1    Broze Jr., G.J.2
  • 23
    • 0025833721 scopus 로고
    • Antithrombotic effects of combining activated protein C with urokinase in primates
    • Gruber, A., Harker, L.A., Hanson, S.R. Griffin, J.G. (1991) Antithrombotic effects of combining activated protein C with urokinase in primates. Circulation, 84, 2454 2462.
    • (1991) Circulation , vol.84 , pp. 2454-2462
    • Gruber, A.1    Harker, L.A.2    Hanson, S.R.3    Griffin, J.G.4
  • 24
    • 0026516880 scopus 로고
    • Liver-specific RNA processing of the ubiquitously transcribed rat fibrinogen γ-chain gene
    • Haidaris, P.J. Courtney, M.A. (1992) Liver-specific RNA processing of the ubiquitously transcribed rat fibrinogen γ-chain gene. Blood, 79, 1218 1224.
    • (1992) Blood , vol.79 , pp. 1218-1224
    • Haidaris, P.J.1    Courtney, M.A.2
  • 25
    • 0024449761 scopus 로고
    • 57.5 chain of human fibrinogen constitute a plasmin sensitive epitope that is exposed in crosslinked fibrin
    • 57.5 chain of human fibrinogen constitute a plasmin sensitive epitope that is exposed in crosslinked fibrin. Blood, 74, 2437 2444.
    • (1989) Blood , vol.74 , pp. 2437-2444
    • Haidaris, P.J.1    Peerschke, E.I.B.2    Marder, V.J.3    Francis, C.W.4
  • 26
  • 27
    • 0022401020 scopus 로고
    • Platelet interactions with Dacron vascular grafts. a model of acute thrombosis in baboons
    • Hanson, S.R., Kotze, H.F., Savage, B. Harker, L.A. (1985) Platelet interactions with Dacron vascular grafts. A model of acute thrombosis in baboons. Arteriosclerosis, 5, 595 603.
    • (1985) Arteriosclerosis , vol.5 , pp. 595-603
    • Hanson, S.R.1    Kotze, H.F.2    Savage, B.3    Harker, L.A.4
  • 29
    • 0032403010 scopus 로고    scopus 로고
    • Clopidogrel inhibition of stent, graft, and vascular thrombogenesis with antithrombotic enhancement by aspirin in nonhuman primates
    • Harker, L.A., Marzec, U.M., Kelly, A.B., Chronos, N.A.F., Sundell, I.B., Hanson, S.R. Herbert, J.-M. (1998) Clopidogrel inhibition of stent, graft, and vascular thrombogenesis with antithrombotic enhancement by aspirin in nonhuman primates. Circulation, 98, 2461 2469.
    • (1998) Circulation , vol.98 , pp. 2461-2469
    • Harker, L.A.1    Marzec, U.M.2    Kelly, A.B.3    Chronos, N.A.F.4    Sundell, I.B.5    Hanson, S.R.6    Herbert, J.-M.7
  • 30
    • 0027326001 scopus 로고
    • Human fibrinogen-structural variants and functional sites
    • Henschen, A.H. (1993) Human fibrinogen-structural variants and functional sites. Thrombosis and Haemostasis, 70, 42 47.
    • (1993) Thrombosis and Haemostasis , vol.70 , pp. 42-47
    • Henschen, A.H.1
  • 32
    • 0023693859 scopus 로고
    • Thrombin binding to the Aα-, Bβ-, and γ-chains of fibrinogen and to their remnants contained in fragment e
    • Kaczmarek, E. McDonagh, J. (1988) Thrombin binding to the Aα-, Bβ-, and γ-chains of fibrinogen and to their remnants contained in fragment E. Journal of Biological Chemistry, 263, 13896 13900.
    • (1988) Journal of Biological Chemistry , vol.263 , pp. 13896-13900
    • Kaczmarek, E.1    McDonagh, J.2
  • 34
    • 0026073345 scopus 로고
    • Hirudin interruption of heparin-resistant arterial thrombus formation in baboons
    • Kelly, A.B., Marzec, U.M., Krupski, W., Bass, A., Cadroy, Y., Hanson, S.R. Harker, L.A. (1991) Hirudin interruption of heparin-resistant arterial thrombus formation in baboons. Blood, 77, 1006 1012.
    • (1991) Blood , vol.77 , pp. 1006-1012
    • Kelly, A.B.1    Marzec, U.M.2    Krupski, W.3    Bass, A.4    Cadroy, Y.5    Hanson, S.R.6    Harker, L.A.7
  • 35
    • 0026748589 scopus 로고
    • Characterization of the γ chain platelet binding site on fibrinogen fragment D
    • Kirschbaum, N.E., Mosesson, M.W. Amrani, D.L. (1992) Characterization of the γ chain platelet binding site on fibrinogen fragment D. Blood, 79, 2643 2648.
    • (1992) Blood , vol.79 , pp. 2643-2648
    • Kirschbaum, N.E.1    Mosesson, M.W.2    Amrani, D.L.3
  • 36
    • 0028007619 scopus 로고
    • The influence of fibrinogen and fibrin on thrombin generation-evidence for feedback activation of the clotting system by clot bound thrombin
    • Kumar, R., Beguin, S. Hemker, H.C. (1994) The influence of fibrinogen and fibrin on thrombin generation-evidence for feedback activation of the clotting system by clot bound thrombin. Thrombosis and Haemostasis, 72, 713 721.
    • (1994) Thrombosis and Haemostasis , vol.72 , pp. 713-721
    • Kumar, R.1    Beguin, S.2    Hemker, H.C.3
  • 42
    • 0029830698 scopus 로고    scopus 로고
    • Identification and characterization of the thrombin binding sites on fibrin
    • Meh, D.A., Siebenlist, K.R. Mosesson, M.W. (1996) Identification and characterization of the thrombin binding sites on fibrin. Journal of Biological Chemistry, 271, 23121 23125.
    • (1996) Journal of Biological Chemistry , vol.271 , pp. 23121-23125
    • Meh, D.A.1    Siebenlist, K.R.2    Mosesson, M.W.3
  • 44
    • 0034612298 scopus 로고    scopus 로고
    • Interactions of human fibrinogens with factor XIII; Roles of calcium and the γ′ peptide
    • Moaddel, M., Farrell, D.H., Daugherty, M.A. Fried, M.G. (2000a) Interactions of human fibrinogens with factor XIII; roles of calcium and the γ′ peptide. Biochemistry, 39, 6698 6705.
    • (2000) Biochemistry , vol.39 , pp. 6698-6705
    • Moaddel, M.1    Farrell, D.H.2    Daugherty, M.A.3    Fried, M.G.4
  • 45
    • 0034644660 scopus 로고    scopus 로고
    • The role of γa/γ′ fibrinogen in plasma factor XIII activation
    • Moaddel, M., Falls, L.A. Farrell, D.H. (2000b) The role of γA/γ′ fibrinogen in plasma factor XIII activation. Journal of Biological Chemistry, 275, 32135 32140.
    • (2000) Journal of Biological Chemistry , vol.275 , pp. 32135-32140
    • Moaddel, M.1    Falls, L.A.2    Farrell, D.H.3
  • 46
    • 0037249459 scopus 로고    scopus 로고
    • Antithrombin I. Inhibition of thrombin generation in plasma by fibrin formation
    • Mosesson, M.W. (2003) Antithrombin I. Inhibition of thrombin generation in plasma by fibrin formation. Thrombosis and Haemostasis, 89, 9 12.
    • (2003) Thrombosis and Haemostasis , vol.89 , pp. 9-12
    • Mosesson, M.W.1
  • 48
    • 0025788582 scopus 로고
    • Activation of human blood coagulation factor XI independent of factor XII
    • Naito, K. Fujikawa, K. (1991) Activation of human blood coagulation factor XI independent of factor XII. Journal of Biological Chemistry, 266, 7353 7358.
    • (1991) Journal of Biological Chemistry , vol.266 , pp. 7353-7358
    • Naito, K.1    Fujikawa, K.2
  • 50
    • 0037821812 scopus 로고    scopus 로고
    • Evidence that both exosites on thrombin participate in its high affinity interaction with fibrin
    • Pospisil, C.H., Stafford, A.R., Fredenburgh, J.C. Weitz, J.I. (2003) Evidence that both exosites on thrombin participate in its high affinity interaction with fibrin. Journal of Biological Chemistry, 278, 21584 21591.
    • (2003) Journal of Biological Chemistry , vol.278 , pp. 21584-21591
    • Pospisil, C.H.1    Stafford, A.R.2    Fredenburgh, J.C.3    Weitz, J.I.4
  • 51
    • 0037176829 scopus 로고    scopus 로고
    • Characterization of the residues involved in the human α-thrombin-haemadin complex: An exosite II-binding inhibitor
    • Richardson, J.L., Fuentes-Prior, P., Sadler, J.E., Huber, R. Bode, W. (2002) Characterization of the residues involved in the human α-thrombin-haemadin complex: an exosite II-binding inhibitor. Biochemistry, 41, 2535 2542.
    • (2002) Biochemistry , vol.41 , pp. 2535-2542
    • Richardson, J.L.1    Fuentes-Prior, P.2    Sadler, J.E.3    Huber, R.4    Bode, W.5
  • 52
    • 9544229716 scopus 로고    scopus 로고
    • Increased thrombolytic and antithrombotic potency of a fibrin-targeted plasminogen activator in baboons
    • Runge, M.S., Harker, L.A., Bode, C., Ruef, J., Kelly, A., Marzec, U.M., Shaw, S., Haber, E. Hanson, S.R. (1996) Increased thrombolytic and antithrombotic potency of a fibrin-targeted plasminogen activator in baboons. Circulation, 94, 1412 1422.
    • (1996) Circulation , vol.94 , pp. 1412-1422
    • Runge, M.S.1    Harker, L.A.2    Bode, C.3    Ruef, J.4    Kelly, A.5    Marzec, U.M.6    Shaw, S.7    Haber, E.8    Hanson, S.R.9
  • 53
    • 0001319829 scopus 로고
    • Note on the adsorption of thrombin on fibrin
    • Seegers, W.H., Nieft, M. Loomis, E.C. (1945) Note on the adsorption of thrombin on fibrin. Science, 101, 520 521.
    • (1945) Science , vol.101 , pp. 520-521
    • Seegers, W.H.1    Nieft, M.2    Loomis, E.C.3
  • 54
    • 0029798238 scopus 로고    scopus 로고
    • Plasma factor XIII binds specifically to fibrinogen molecules containing γ′ chains
    • Siebenlist, K.R., Meh, D.A. Mosesson, M.W. (1996) Plasma factor XIII binds specifically to fibrinogen molecules containing γ′ chains. Biochemistry, 35, 10448 10453.
    • (1996) Biochemistry , vol.35 , pp. 10448-10453
    • Siebenlist, K.R.1    Meh, D.A.2    Mosesson, M.W.3
  • 56
    • 0022521744 scopus 로고
    • Kinetics of the inhibition of thrombin by hirudin
    • Stone, S.R. Hofsteenge, J. (1986) Kinetics of the inhibition of thrombin by hirudin. Biochemistry, 25, 4622 4628.
    • (1986) Biochemistry , vol.25 , pp. 4622-4628
    • Stone, S.R.1    Hofsteenge, J.2
  • 57
    • 0031563773 scopus 로고    scopus 로고
    • Oligonucleotide inhibitors of human thrombin that bind distinct epitopes
    • Tasset, D.M., Kubik, M.F. Steiner, W. (1997) Oligonucleotide inhibitors of human thrombin that bind distinct epitopes. Journal of Molecular Biology, 272, 688 698.
    • (1997) Journal of Molecular Biology , vol.272 , pp. 688-698
    • Tasset, D.M.1    Kubik, M.F.2    Steiner, W.3
  • 60
    • 0026771894 scopus 로고
    • Computer modeling of fibrin polymerization kinetics correlated with electron microscope and turbidity observations: Clot structure and assembly are kinetically controlled
    • Weisel, J.W. Nagaswami, C. (1992) Computer modeling of fibrin polymerization kinetics correlated with electron microscope and turbidity observations: clot structure and assembly are kinetically controlled. Biophysical Journal, 63, 111 128.
    • (1992) Biophysical Journal , vol.63 , pp. 111-128
    • Weisel, J.W.1    Nagaswami, C.2
  • 61
    • 33947104111 scopus 로고    scopus 로고
    • Beyond heparin and warfarin: The new generation of anticoagulants
    • Weitz, J.I. Linkins, L.A. (2007) Beyond heparin and warfarin: the new generation of anticoagulants. Expert Opinion on Investigational Drugs, 16, 271 282.
    • (2007) Expert Opinion on Investigational Drugs , vol.16 , pp. 271-282
    • Weitz, J.I.1    Linkins, L.A.2
  • 62
    • 0025146426 scopus 로고
    • Clot-bound thrombin is protected from inhibition by heparin-antithrombin III but is susceptible to inactivation by antithrombin III-independent inhibitors
    • Weitz, J.I., Hudoba, M., Massel, D., Maraganore, J. Hirsh, J. (1990) Clot-bound thrombin is protected from inhibition by heparin-antithrombin III but is susceptible to inactivation by antithrombin III-independent inhibitors. Journal of Clinical Investigation, 86, 385 391.
    • (1990) Journal of Clinical Investigation , vol.86 , pp. 385-391
    • Weitz, J.I.1    Hudoba, M.2    Massel, D.3    Maraganore, J.4    Hirsh, J.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.