2.8 Å crystal structures of recombinant fibrinogen fragment D with and without two peptide ligands: GHRP binding to the "b" site disrupts its nearby calcium-binding site

Biochemistry

Volumn 41, Issue 40, 2002, Pages 12124-12132

  Kostelansky, Michael S ^a   Betts, Laurie ^b   Gorkun, Oleg V ^b   Lord, Susan T ^a,b  

^a University of North Carolina at Chapel Hill   (United States)

^b UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PEPTIDE LIGANDS;

CALCIUM; CARBOHYDRATES; CRYSTAL STRUCTURE; POLYMERIZATION; STRUCTURAL ANALYSIS;

PROTEINS;

CALCIUM; FIBRINOGEN; FUCOSE; GLYCYLHISTIDYLARGINYLPROLINE; LIGAND; PEPTIDE; RECOMBINANT FIBRINOGEN FRAGMENT D; THROMBIN; UNCLASSIFIED DRUG; CARBOHYDRATE; FIBRIN DEGRADATION PRODUCT; FIBRINOGEN D FRAGMENT; GLYCYL HISTIDYL ARGINYL PROLINE; GLYCYL PROLYL ARGINYL PROLINE; GLYCYL-HISTIDYL-ARGINYL-PROLINE; GLYCYL-PROLYL-ARGINYL-PROLINE; OLIGOPEPTIDE;

ARTICLE; BINDING SITE; CALCIUM BINDING; CRYSTAL STRUCTURE; LIGAND BINDING; OPTICAL RESOLUTION; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN STRUCTURE; ANIMAL; CHEMISTRY; CHO CELL; HAMSTER; HUMAN; METABOLISM; PHYSIOLOGY; PROTEIN TERTIARY STRUCTURE; X RAY CRYSTALLOGRAPHY;

ANIMALS; BINDING SITES; CALCIUM; CARBOHYDRATES; CHO CELLS; CRICETINAE; CRYSTALLOGRAPHY, X-RAY; FIBRIN FIBRINOGEN DEGRADATION PRODUCTS; HUMANS; LIGANDS; OLIGOPEPTIDES; PROTEIN STRUCTURE, TERTIARY;

EID: 0037044194     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi0261894     Document Type: Article

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