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Volumn 106, Issue 13, 2005, Pages 4176-4183

Genetic variation in the fibrinogen gamma gene increases the risk for deep venous thrombosis by reducing plasma fibrinogen γ′ levels

Author keywords

[No Author keywords available]

Indexed keywords

FIBRINOGEN;

EID: 28844473918     PISSN: 00064971     EISSN: 00064971     Source Type: Journal    
DOI: 10.1182/blood-2005-05-2180     Document Type: Article
Times cited : (216)

References (67)
  • 1
    • 0034964447 scopus 로고    scopus 로고
    • The structure and biological features of fibrinogen and fibrin
    • Mosesson MW, Siebenlist KR, Meh DA. The structure and biological features of fibrinogen and fibrin. Ann N Y Acad Sci. 2001;936:11-30.
    • (2001) Ann N Y Acad Sci , vol.936 , pp. 11-30
    • Mosesson, M.W.1    Siebenlist, K.R.2    Meh, D.A.3
  • 2
    • 0034972479 scopus 로고    scopus 로고
    • Factor XIII: Structure, activation, and interactions with fibrinogen and fibrin
    • Lorand L. Factor XIII: structure, activation, and interactions with fibrinogen and fibrin. Ann N Y Acad Sci. 2001;936:291-311.
    • (2001) Ann N Y Acad Sci , vol.936 , pp. 291-311
    • Lorand, L.1
  • 3
    • 0018386560 scopus 로고
    • Fibrin crosslinks and lysis rates
    • Gaffney PJ, Whitaker AN. Fibrin crosslinks and lysis rates. Thromb Res. 1979;14:85-94.
    • (1979) Thromb Res , vol.14 , pp. 85-94
    • Gaffney, P.J.1    Whitaker, A.N.2
  • 4
    • 0026806596 scopus 로고
    • Platelet factor XIII increases the fibrinolytic resistance of platelet-rich clots by accelerating the crosslinking of alpha 2-antiplasmin to fibrin
    • Reed GL, Matsueda GR, Haber E. Platelet factor XIII increases the fibrinolytic resistance of platelet-rich clots by accelerating the crosslinking of alpha 2-antiplasmin to fibrin. Thromb Haemost. 1992;68:315-320.
    • (1992) Thromb Haemost , vol.68 , pp. 315-320
    • Reed, G.L.1    Matsueda, G.R.2    Haber, E.3
  • 5
    • 0027993303 scopus 로고
    • Progressive crosslinking of fibrin gamma chains increases resistance to fibrinolysis
    • Siebenlist KR, Mosesson MW. Progressive crosslinking of fibrin gamma chains increases resistance to fibrinolysis. J Biol Chem. 1994;269:28414-28419.
    • (1994) J Biol Chem , vol.269 , pp. 28414-28419
    • Siebenlist, K.R.1    Mosesson, M.W.2
  • 7
    • 0000751868 scopus 로고
    • Evolution and organization of the fibrinogen locus on chromosome 4: Gene duplication accompanied by transposition and inversion
    • U S A
    • Kant JA, Fornace AJ Jr, Saxe D, et al. Evolution and organization of the fibrinogen locus on chromosome 4: gene duplication accompanied by transposition and inversion. Proc Natl Acad Sci U S A. 1985;82:2344-2348.
    • (1985) Proc Natl Acad Sci , vol.82 , pp. 2344-2348
    • Kant, J.A.1    Fornace Jr., A.J.2    Saxe, D.3
  • 9
    • 0028179782 scopus 로고
    • Fib420: A normal human variant of fibrinogen with two extended alpha chains
    • U S A
    • Fu Y, Grieninger G. Fib420: a normal human variant of fibrinogen with two extended alpha chains. Proc Natl Acad Sci U S A. 1994;91:2625-2628.
    • (1994) Proc Natl Acad Sci , vol.91 , pp. 2625-2628
    • Fu, Y.1    Grieninger, G.2
  • 10
    • 0019769991 scopus 로고
    • Carboxyterminal amino acid sequence of a human fibrinogen gamma-chain variant (gamma′)
    • Wolfenstein-Todel C, Mosesson MW. Carboxyterminal amino acid sequence of a human fibrinogen gamma-chain variant (gamma′). Biochemistry. 1981;20:6146-6149.
    • (1981) Biochemistry , vol.20 , pp. 6146-6149
    • Wolfenstein-Todel, C.1    Mosesson, M.W.2
  • 11
    • 0028342850 scopus 로고
    • Factor VII and fibrinogen levels as risk factors for venous thrombosis: A case-control study of plasma levels and DNA polymorphisms - The Leiden Thrombophilia Study (LETS)
    • Koster T, Rosendaal FR, Reitsma PH, et al. Factor VII and fibrinogen levels as risk factors for venous thrombosis: a case-control study of plasma levels and DNA polymorphisms - the Leiden Thrombophilia Study (LETS). Thromb Haemost. 1994;71:719-722.
    • (1994) Thromb Haemost , vol.71 , pp. 719-722
    • Koster, T.1    Rosendaal, F.R.2    Reitsma, P.H.3
  • 12
    • 1542544882 scopus 로고    scopus 로고
    • High levels of fibrinogen are associated with the risk of deep venous thrombosis mainly in the elderly
    • van Hylckama Vlieg A, Rosendaal FR. High levels of fibrinogen are associated with the risk of deep venous thrombosis mainly in the elderly. J Thromb Haemost. 2003;1:2677-2678.
    • (2003) J Thromb Haemost , vol.1 , pp. 2677-2678
    • Van Hylckama Vlieg, A.1    Rosendaal, F.R.2
  • 13
    • 0037395239 scopus 로고    scopus 로고
    • Fibrin(ogen) in cardiovascular disease: An update
    • Koenig W. Fibrin(ogen) in cardiovascular disease: an update. Thromb Haemost. 2003;89:601-609.
    • (2003) Thromb Haemost , vol.89 , pp. 601-609
    • Koenig, W.1
  • 14
    • 0032765219 scopus 로고    scopus 로고
    • Dysfibrinogenemia and thrombosis
    • Mosesson MW. Dysfibrinogenemia and thrombosis. Semin Thromb Hemost. 1999;25:311-319.
    • (1999) Semin Thromb Hemost , vol.25 , pp. 311-319
    • Mosesson, M.W.1
  • 15
    • 0034975060 scopus 로고    scopus 로고
    • A database for human fibrinogen variants
    • Hanss M, Biot F. A database for human fibrinogen variants. Ann N Y Acad Sci. 2001;936:89-90.
    • (2001) Ann N Y Acad Sci , vol.936 , pp. 89-90
    • Hanss, M.1    Biot, F.2
  • 16
    • 0028877613 scopus 로고
    • Familial dysfibrinogenemia and thrombophilia: Report on a study of the SSC Subcommittee on Fibrinogen
    • Haverkate F, Samama M. Familial dysfibrinogenemia and thrombophilia: report on a study of the SSC Subcommittee on Fibrinogen. Thromb Haemost. 1995;73:151-161.
    • (1995) Thromb Haemost , vol.73 , pp. 151-161
    • Haverkate, F.1    Samama, M.2
  • 17
    • 0027520285 scopus 로고
    • Venous thrombosis due to poor anticoagulant response to activated protein C: Leiden Thrombophilia Study
    • Koster T, Rosendaal FR, de Ronde H, et al. Venous thrombosis due to poor anticoagulant response to activated protein C: Leiden Thrombophilia Study. Lancet. 1993;342:1503-1506.
    • (1993) Lancet , vol.342 , pp. 1503-1506
    • Koster, T.1    Rosendaal, F.R.2    De Ronde, H.3
  • 19
    • 0035071957 scopus 로고    scopus 로고
    • A new statistical method for haplotype reconstruction from population data
    • Stephens M, Smith NJ, Donnelly P. A new statistical method for haplotype reconstruction from population data. Am J Hum Genet. 2001;68:978-989.
    • (2001) Am J Hum Genet , vol.68 , pp. 978-989
    • Stephens, M.1    Smith, N.J.2    Donnelly, P.3
  • 20
    • 1842435261 scopus 로고    scopus 로고
    • Haplotype diversity across 100 candidate genes for inflammation, lipid metabolism, and blood pressure regulation in two populations
    • Crawford DC, Carlson CS, Rieder MJ, et al. Haplotype diversity across 100 candidate genes for inflammation, lipid metabolism, and blood pressure regulation in two populations. Am J Hum Genet. 2004;74:610-622.
    • (2004) Am J Hum Genet , vol.74 , pp. 610-622
    • Crawford, D.C.1    Carlson, C.S.2    Rieder, M.J.3
  • 21
    • 0021184750 scopus 로고
    • Gamma and gamma′ chains of human fibrinogen are produced by alternative mRNA processing
    • Chung DW, Davie EW. Gamma and gamma′ chains of human fibrinogen are produced by alternative mRNA processing. Biochemistry. 1984;23:4232-4236.
    • (1984) Biochemistry , vol.23 , pp. 4232-4236
    • Chung, D.W.1    Davie, E.W.2
  • 22
    • 0021744551 scopus 로고
    • Structure of the human gamma-fibrinogen gene: Alternate mRNA splicing near the 3′ end of the gene produces gamma A and gamma B forms of gamma-fibrinogen
    • Fornace AJ Jr, Cummings DE, Comeau CM, Kant JA, Crabtree GR. Structure of the human gamma-fibrinogen gene: alternate mRNA splicing near the 3′ end of the gene produces gamma A and gamma B forms of gamma-fibrinogen. J Biol Chem. 1984;259:12826-12830.
    • (1984) J Biol Chem , vol.259 , pp. 12826-12830
    • Fornace Jr., A.J.1    Cummings, D.E.2    Comeau, C.M.3    Kant, J.A.4    Crabtree, G.R.5
  • 23
    • 1042289587 scopus 로고
    • Human plasma fibrinogen heterogeneity: Evidence for an extended carboxyl-terminal sequence in a normal gamma chain variant (gamma′)
    • U S A
    • Wolfenstein-Todel C, Mosesson MW. Human plasma fibrinogen heterogeneity: evidence for an extended carboxyl-terminal sequence in a normal gamma chain variant (gamma′). Proc Natl Acad Sci U S A. 1980;77:5069-5073.
    • (1980) Proc Natl Acad Sci , vol.77 , pp. 5069-5073
    • Wolfenstein-Todel, C.1    Mosesson, M.W.2
  • 24
    • 0033006003 scopus 로고    scopus 로고
    • Allelic discrimination using fluorogenic probes and the 5′ nuclease assay
    • Livak KJ. Allelic discrimination using fluorogenic probes and the 5′ nuclease assay. Genet Anal. 1999;14:143-149.
    • (1999) Genet Anal , vol.14 , pp. 143-149
    • Livak, K.J.1
  • 25
    • 0036301930 scopus 로고    scopus 로고
    • Association of γA/gamma′ fibrinogen levels and coronary artery disease
    • Lovely RS, Falls LA, Al Mondhiry HA, et al. Association of γA/gamma′ fibrinogen levels and coronary artery disease. Thromb Haemost. 2002;88:26-31.
    • (2002) Thromb Haemost , vol.88 , pp. 26-31
    • Lovely, R.S.1    Falls, L.A.2    Al Mondhiry, H.A.3
  • 27
    • 0037923219 scopus 로고    scopus 로고
    • Fibrinogen gamma′ chain binds thrombin exosite II
    • Lovely RS, Moaddel M, Farrell DH. Fibrinogen gamma′ chain binds thrombin exosite II. J Thromb Haemost. 2003;1:124-131.
    • (2003) J Thromb Haemost , vol.1 , pp. 124-131
    • Lovely, R.S.1    Moaddel, M.2    Farrell, D.H.3
  • 28
    • 0344410771 scopus 로고    scopus 로고
    • Inference on haplotype effects in case-control studies using unphased genotype data
    • Epstein MP, Satten GA. Inference on haplotype effects in case-control studies using unphased genotype data. Am J Hum Genet. 2003;73:1316-1329.
    • (2003) Am J Hum Genet , vol.73 , pp. 1316-1329
    • Epstein, M.P.1    Satten, G.A.2
  • 30
    • 84960989652 scopus 로고
    • On estimating the relation between blood group and disease
    • Woolf B. On estimating the relation between blood group and disease. Ann Hum Genet. 1955;19:251-253.
    • (1955) Ann Hum Genet , vol.19 , pp. 251-253
    • Woolf, B.1
  • 31
    • 13444269543 scopus 로고    scopus 로고
    • Haploview: Analysis and visualization of LD and haplotype maps
    • Barrett JC, Fry B, Maller J, Daly MJ. Haploview: analysis and visualization of LD and haplotype maps. Bioinformatics. 2005;21:263-265.
    • (2005) Bioinformatics , vol.21 , pp. 263-265
    • Barrett, J.C.1    Fry, B.2    Maller, J.3    Daly, M.J.4
  • 33
    • 0037341535 scopus 로고    scopus 로고
    • Obesity: Risk of venous thrombosis and the interaction with coagulation factor levels and oral contraceptive use
    • Abdollahi M, Cushman M, Rosendaal FR. Obesity: risk of venous thrombosis and the interaction with coagulation factor levels and oral contraceptive use. Thromb Haemost. 2003;89:493-498.
    • (2003) Thromb Haemost , vol.89 , pp. 493-498
    • Abdollahi, M.1    Cushman, M.2    Rosendaal, F.R.3
  • 34
    • 0029850530 scopus 로고    scopus 로고
    • A common genetic variation in the 3′-untranslated region of the prothrombin gene is associated with elevated plasma prothrombin levels and an increase in venous thrombosis
    • Poort SR, Rosendaal FR, Reitsma PH, Bertina RM. A common genetic variation in the 3′-untranslated region of the prothrombin gene is associated with elevated plasma prothrombin levels and an increase in venous thrombosis. Blood. 1996;88:3698-3703.
    • (1996) Blood , vol.88 , pp. 3698-3703
    • Poort, S.R.1    Rosendaal, F.R.2    Reitsma, P.H.3    Bertina, R.M.4
  • 35
    • 0028814316 scopus 로고
    • Role of clotting factor VIII in effect of von Willebrand factor on occurrence of deepvein thrombosis
    • Koster T, Blann AD, Briët E, Vandenbroucke JP, Rosendaal FR. Role of clotting factor VIII in effect of von Willebrand factor on occurrence of deepvein thrombosis. Lancet. 1995;345:152-155.
    • (1995) Lancet , vol.345 , pp. 152-155
    • Koster, T.1    Blann, A.D.2    Briët, E.3    Vandenbroucke, J.P.4    Rosendaal, F.R.5
  • 38
    • 0032934812 scopus 로고    scopus 로고
    • Increased levels of factor VIII and fibrinogen in patients with venous thrombosis are not caused by acute phase reactions
    • Kamphuisen PW, Eikenboom JC, Vos HL, et al. Increased levels of factor VIII and fibrinogen in patients with venous thrombosis are not caused by acute phase reactions. Thromb Haemost. 1999;81:680-683.
    • (1999) Thromb Haemost , vol.81 , pp. 680-683
    • Kamphuisen, P.W.1    Eikenboom, J.C.2    Vos, H.L.3
  • 40
    • 0034964449 scopus 로고    scopus 로고
    • Fibrinogen polymorphisms and atherothrombotic disease
    • Green FR. Fibrinogen polymorphisms and atherothrombotic disease. Ann N Y Acad Sci. 2001;936:549-559.
    • (2001) Ann N Y Acad Sci , vol.936 , pp. 549-559
    • Green, F.R.1
  • 41
    • 15344343051 scopus 로고    scopus 로고
    • Contribution of haplotypes across the fibrinogen gene cluster to variation in risk of myocardial infarction
    • Mannila MN, Eriksson P, Lundman P, et al. Contribution of haplotypes across the fibrinogen gene cluster to variation in risk of myocardial infarction. Thromb Haemost. 2005;93:570-577.
    • (2005) Thromb Haemost , vol.93 , pp. 570-577
    • Mannila, M.N.1    Eriksson, P.2    Lundman, P.3
  • 42
    • 0026692869 scopus 로고
    • Genetic variation at fibrinogen loci and plasma fibrinogen levels
    • Connor JM, Fowkes FG, Wood J, et al. Genetic variation at fibrinogen loci and plasma fibrinogen levels. J Med Genet. 1992;29:480-482.
    • (1992) J Med Genet , vol.29 , pp. 480-482
    • Connor, J.M.1    Fowkes, F.G.2    Wood, J.3
  • 43
    • 0030705196 scopus 로고    scopus 로고
    • RNA ligands selected by cleavage stimulation factor contain distinct sequence motifs that function as downstream elements in 3′-end processing of premRNA
    • Beyer K, Dandekar T, Keller W. RNA ligands selected by cleavage stimulation factor contain distinct sequence motifs that function as downstream elements in 3′-end processing of premRNA. J Biol Chem. 1997;272:26769-26779.
    • (1997) J Biol Chem , vol.272 , pp. 26769-26779
    • Beyer, K.1    Dandekar, T.2    Keller, W.3
  • 44
    • 0028899452 scopus 로고
    • Genetic regulation of fibrinogen
    • Humphries SE. Genetic regulation of fibrinogen. Eur Heart J. 1995;16(suppl A):16-19.
    • (1995) Eur Heart J , vol.16 , Issue.SUPPL. A , pp. 16-19
    • Humphries, S.E.1
  • 46
    • 1442283453 scopus 로고    scopus 로고
    • Genetics of fibrin clot structure: A twin study
    • Dunn EJ, Ariens RA, de Lange M, et al. Genetics of fibrin clot structure: a twin study. Blood. 2004;103:1735-1740.
    • (2004) Blood , vol.103 , pp. 1735-1740
    • Dunn, E.J.1    Ariens, R.A.2    De Lange, M.3
  • 47
    • 0034603799 scopus 로고    scopus 로고
    • Genetic determinants of hemostasis phenotypes in Spanish families
    • Souto JC, Almasy L, Borrell M, et al. Genetic determinants of hemostasis phenotypes in Spanish families. Circulation. 2000;101:1546-1551.
    • (2000) Circulation , vol.101 , pp. 1546-1551
    • Souto, J.C.1    Almasy, L.2    Borrell, M.3
  • 48
    • 0038107521 scopus 로고    scopus 로고
    • A genome-wide search for genes affecting circulating fibrinogen levels in the Framingham Heart Study
    • Yang Q, Tofler GH, Cupples LA, et al. A genome-wide search for genes affecting circulating fibrinogen levels in the Framingham Heart Study. Thromb Res. 2003;110:57-64.
    • (2003) Thromb Res , vol.110 , pp. 57-64
    • Yang, Q.1    Tofler, G.H.2    Cupples, L.A.3
  • 49
    • 20144367081 scopus 로고    scopus 로고
    • A genome search for genetic determinants that influence plasma fibrinogen levels
    • Soria JM, Almasy L, Souto JC, et al. A genome search for genetic determinants that influence plasma fibrinogen levels. Arterioscler Thromb Vasc Biol. 2005;25:1287-1292.
    • (2005) Arterioscler Thromb Vasc Biol , vol.25 , pp. 1287-1292
    • Soria, J.M.1    Almasy, L.2    Souto, J.C.3
  • 50
    • 0038494830 scopus 로고    scopus 로고
    • Fibrinogen gamma-chain splice variant γ′ alters fibrin formation and structure
    • Cooper AV, Standeven KF, Ariëns RA. Fibrinogen gamma-chain splice variant γ′ alters fibrin formation and structure. Blood. 2003;102:535-540.
    • (2003) Blood , vol.102 , pp. 535-540
    • Cooper, A.V.1    Standeven, K.F.2    Ariëns, R.A.3
  • 51
    • 0034612298 scopus 로고    scopus 로고
    • Interactions of human fibrinogens with factor XIII: Roles of calcium and the gamma′ peptide
    • Moaddel M, Farrell DH, Daugherty MA, Fried MG. Interactions of human fibrinogens with factor XIII: roles of calcium and the gamma′ peptide. Biochemistry. 2000;39:6698-6705.
    • (2000) Biochemistry , vol.39 , pp. 6698-6705
    • Moaddel, M.1    Farrell, D.H.2    Daugherty, M.A.3    Fried, M.G.4
  • 52
    • 0030611710 scopus 로고    scopus 로고
    • Resistance of γA/γ′ fibrin clots to fibrinolysis
    • Falls LA, Farrell DH. Resistance of γA/γ′ fibrin clots to fibrinolysis. J Biol Chem. 1997;272:14251-14256.
    • (1997) J Biol Chem , vol.272 , pp. 14251-14256
    • Falls, L.A.1    Farrell, D.H.2
  • 54
    • 0141450410 scopus 로고    scopus 로고
    • Fibrinogen gamma chain functions
    • Mosesson MW. Fibrinogen gamma chain functions. J Thromb Haemost. 2003;1:231-238.
    • (2003) J Thromb Haemost , vol.1 , pp. 231-238
    • Mosesson, M.W.1
  • 55
    • 0018631259 scopus 로고
    • The binding of thrombin by fibrin
    • Liu CY, Nossel HL, Kaplan KL. The binding of thrombin by fibrin. J Biol Chem. 1979;254:10421-10425.
    • (1979) J Biol Chem , vol.254 , pp. 10421-10425
    • Liu, C.Y.1    Nossel, H.L.2    Kaplan, K.L.3
  • 56
    • 0037249459 scopus 로고    scopus 로고
    • Antithrombin I: Inhibition of thrombin generation in plasma by fibrin formation
    • Mosesson MW. Antithrombin I: inhibition of thrombin generation in plasma by fibrin formation. Thromb Haemost. 2003;89:9-12.
    • (2003) Thromb Haemost , vol.89 , pp. 9-12
    • Mosesson, M.W.1
  • 57
    • 0029830698 scopus 로고    scopus 로고
    • Identification and characterization of the thrombin binding sites on fibrin
    • Meh DA, Siebenlist KR, Mosesson MW. Identification and characterization of the thrombin binding sites on fibrin. J Biol Chem. 1996;271:23121-23125.
    • (1996) J Biol Chem , vol.271 , pp. 23121-23125
    • Meh, D.A.1    Siebenlist, K.R.2    Mosesson, M.W.3
  • 58
    • 0001319829 scopus 로고
    • Note on the adsorption of thrombin on fibrin
    • Seegers WH, Nieft M, Loomis EC. Note on the adsorption of thrombin on fibrin. Science. 1945;101:520-521.
    • (1945) Science , vol.101 , pp. 520-521
    • Seegers, W.H.1    Nieft, M.2    Loomis, E.C.3
  • 59
    • 0344721707 scopus 로고
    • The nature of plasma antithrombin activity
    • Klein PD, Seegers WH. The nature of plasma antithrombin activity. Blood. 1950;5:742-752.
    • (1950) Blood , vol.5 , pp. 742-752
    • Klein, P.D.1    Seegers, W.H.2
  • 60
    • 0025146426 scopus 로고
    • Clot-bound thrombin is protected from inhibition by heparin-antithrombin III but is susceptible to inactivation by antithrombin III-independent inhibitors
    • Weitz JI, Hudoba M, Massel D, Maraganore J, Hirsh J. Clot-bound thrombin is protected from inhibition by heparin-antithrombin III but is susceptible to inactivation by antithrombin III-independent inhibitors. J Clin Invest. 1990;86:385-391.
    • (1990) J Clin Invest , vol.86 , pp. 385-391
    • Weitz, J.I.1    Hudoba, M.2    Massel, D.3    Maraganore, J.4    Hirsh, J.5
  • 61
    • 27144433871 scopus 로고    scopus 로고
    • Studies on the basis for the properties of fibrin produced from fibrinogen-containing γ′ chains
    • Siebenlist KR, Mosesson MW, Hernandez I, et al. Studies on the basis for the properties of fibrin produced from fibrinogen-containing γ′ chains. Blood. 2005;106:2730-2736.
    • (2005) Blood , vol.106 , pp. 2730-2736
    • Siebenlist, K.R.1    Mosesson, M.W.2    Hernandez, I.3
  • 63
    • 0033069413 scopus 로고    scopus 로고
    • Plasma gamma′/gamma fibrinogen ratio, a marker of arterial thrombotic activity: A new potential cardiovascular risk factor?
    • Drouet L, Paolucci F, Pasqualini N, et al. Plasma gamma′/gamma fibrinogen ratio, a marker of arterial thrombotic activity: a new potential cardiovascular risk factor? Blood Coagul Fibrinolysis. 1999;(suppl 1):S35-S39.
    • (1999) Blood Coagul Fibrinolysis , Issue.1 SUPPL.
    • Drouet, L.1    Paolucci, F.2    Pasqualini, N.3
  • 64
    • 0037418247 scopus 로고    scopus 로고
    • No evidence of association between prothrombotic gene polymorphisms and the development of acute myocardial infarction at a young age
    • Atherosclerosis, Thrombosis, and Vascular Biology Italian Study Group. No evidence of association between prothrombotic gene polymorphisms and the development of acute myocardial infarction at a young age. Circulation. 2003;107:1117-1122.
    • (2003) Circulation , vol.107 , pp. 1117-1122
  • 65
    • 0027428484 scopus 로고
    • Human fibrinogen polymorphic site analysis by restriction endonuclease digestion and allele-specific polymerase chain reaction amplification: Identification of polymorphisms at positions A alpha 312 and B beta 448
    • Baumann RE, Henschen AH. Human fibrinogen polymorphic site analysis by restriction endonuclease digestion and allele-specific polymerase chain reaction amplification: identification of polymorphisms at positions A alpha 312 and B beta 448. Blood. 1993;82:2117-2124.
    • (1993) Blood , vol.82 , pp. 2117-2124
    • Baumann, R.E.1    Henschen, A.H.2
  • 66
    • 0037986620 scopus 로고    scopus 로고
    • Functional analysis of the fibrinogen Aα Thr312Ala polymorphism: Effects on fibrin structure and function
    • Standeven KF, Grant PJ, Carter AM, et al. Functional analysis of the fibrinogen Aα Thr312Ala polymorphism: effects on fibrin structure and function. Circulation. 2003;107:2326-2330.
    • (2003) Circulation , vol.107 , pp. 2326-2330
    • Standeven, K.F.1    Grant, P.J.2    Carter, A.M.3
  • 67
    • 0034254277 scopus 로고    scopus 로고
    • α-Fibrinogen Thr312Ala polymorphism and venous thromboembolism
    • Carter AM, Catto AJ, Kohler HP, et al. α-Fibrinogen Thr312Ala polymorphism and venous thromboembolism. Blood. 2000;96:1177-1179.
    • (2000) Blood , vol.96 , pp. 1177-1179
    • Carter, A.M.1    Catto, A.J.2    Kohler, H.P.3


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