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Volumn 86, Issue 4, 2008, Pages 406-416

Evaluating epigenetic landmarks in the brain of multiple sclerosis patients: A contribution to the current debate on disease pathogenesis

Author keywords

Chromatin; DNA methylation; Epigenetics; Histone; Multiple sclerosis

Indexed keywords

GLUCOCORTICOID; HISTONE; HISTONE DEACETYLASE INHIBITOR; LYSINE; TRICHOSTATIN A;

EID: 57049160500     PISSN: 03010082     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.pneurobio.2008.09.012     Document Type: Review
Times cited : (39)

References (202)
  • 1
    • 33745099273 scopus 로고    scopus 로고
    • Histone deacetylation: an important mechanism in inflammatory lung diseases
    • Adcock I.M., Ito K., and Barnes P.J. Histone deacetylation: an important mechanism in inflammatory lung diseases. COPD 2 (2005) 445-455
    • (2005) COPD , vol.2 , pp. 445-455
    • Adcock, I.M.1    Ito, K.2    Barnes, P.J.3
  • 2
    • 33947547648 scopus 로고    scopus 로고
    • Extensive cortical remyelination in patients with chronic multiple sclerosis
    • Albert M., Antel J., Bruck W., and Stadelmann C. Extensive cortical remyelination in patients with chronic multiple sclerosis. Brain Pathol. 17 (2007) 129-138
    • (2007) Brain Pathol. , vol.17 , pp. 129-138
    • Albert, M.1    Antel, J.2    Bruck, W.3    Stadelmann, C.4
  • 3
    • 37249024572 scopus 로고    scopus 로고
    • Structure and mechanism of lysine specific demethylase enzymes
    • Anand R., and Marmorstein R. Structure and mechanism of lysine specific demethylase enzymes. J. Biol. Chem. 282 (2007) 35425-35429
    • (2007) J. Biol. Chem. , vol.282 , pp. 35425-35429
    • Anand, R.1    Marmorstein, R.2
  • 4
    • 0032563941 scopus 로고    scopus 로고
    • Transcriptional control: repression by local chromatin modification
    • Ashraf S.I., and Ip Y.T. Transcriptional control: repression by local chromatin modification. Curr. Biol. 8 (1998) R683-686
    • (1998) Curr. Biol. , vol.8
    • Ashraf, S.I.1    Ip, Y.T.2
  • 5
    • 34547596890 scopus 로고    scopus 로고
    • Id sustains Hes1 expression to inhibit precocious neurogenesis by releasing negative autoregulation of Hes1
    • Bai G., Sheng N., Xie Z., Bian W., Yokota Y., Benezra R., Kageyama R., Guillemot F., and Jing N. Id sustains Hes1 expression to inhibit precocious neurogenesis by releasing negative autoregulation of Hes1. Dev. Cell 13 (2007) 283-297
    • (2007) Dev. Cell , vol.13 , pp. 283-297
    • Bai, G.1    Sheng, N.2    Xie, Z.3    Bian, W.4    Yokota, Y.5    Benezra, R.6    Kageyama, R.7    Guillemot, F.8    Jing, N.9
  • 6
    • 24144475284 scopus 로고    scopus 로고
    • Reversing histone methylation
    • Bannister A.J., and Kouzarides T. Reversing histone methylation. Nature 436 (2005) 1103-1106
    • (2005) Nature , vol.436 , pp. 1103-1106
    • Bannister, A.J.1    Kouzarides, T.2
  • 7
    • 0037188911 scopus 로고    scopus 로고
    • Histone methylation: dynamic or static?
    • Bannister A.J., Schneider R., and Kouzarides T. Histone methylation: dynamic or static?. Cell 109 (2002) 801-806
    • (2002) Cell , vol.109 , pp. 801-806
    • Bannister, A.J.1    Schneider, R.2    Kouzarides, T.3
  • 8
    • 1642281535 scopus 로고    scopus 로고
    • Relapsing and remitting multiple sclerosis: pathology of the newly forming lesion
    • Barnett M.H., and Prineas J.W. Relapsing and remitting multiple sclerosis: pathology of the newly forming lesion. Ann. Neurol. 55 (2004) 458-468
    • (2004) Ann. Neurol. , vol.55 , pp. 458-468
    • Barnett, M.H.1    Prineas, J.W.2
  • 9
    • 33744472199 scopus 로고    scopus 로고
    • The pathology of multiple sclerosis: a paradigm shift
    • Barnett M.H., and Sutton I. The pathology of multiple sclerosis: a paradigm shift. Curr. Opin. Neurol. 19 (2006) 242-247
    • (2006) Curr. Opin. Neurol. , vol.19 , pp. 242-247
    • Barnett, M.H.1    Sutton, I.2
  • 11
    • 33745631754 scopus 로고    scopus 로고
    • Antigen presentation in autoimmunity and CNS inflammation: how T lymphocytes recognize the brain
    • Becher B., Bechmann I., and Greter M. Antigen presentation in autoimmunity and CNS inflammation: how T lymphocytes recognize the brain. J. Mol. Med. (Berlin, Germany) 84 (2006) 532-543
    • (2006) J. Mol. Med. (Berlin, Germany) , vol.84 , pp. 532-543
    • Becher, B.1    Bechmann, I.2    Greter, M.3
  • 12
    • 20844450998 scopus 로고    scopus 로고
    • Arginine methylation an emerging regulator of protein function
    • Bedford M.T., and Richard S. Arginine methylation an emerging regulator of protein function. Mol. Cell 18 (2005) 263-272
    • (2005) Mol. Cell , vol.18 , pp. 263-272
    • Bedford, M.T.1    Richard, S.2
  • 14
    • 0036532026 scopus 로고    scopus 로고
    • Histone modifications in transcriptional regulation
    • Berger S.L. Histone modifications in transcriptional regulation. Curr. Opin. Genet. Dev. 12 (2002) 142-148
    • (2002) Curr. Opin. Genet. Dev. , vol.12 , pp. 142-148
    • Berger, S.L.1
  • 15
    • 0033601073 scopus 로고    scopus 로고
    • Methylation-induced repression-belts, braces, and chromatin
    • Bird A.P., and Wolffe A.P. Methylation-induced repression-belts, braces, and chromatin. Cell 99 (1999) 451-454
    • (1999) Cell , vol.99 , pp. 451-454
    • Bird, A.P.1    Wolffe, A.P.2
  • 16
    • 33645607060 scopus 로고    scopus 로고
    • Protein interfaces in signaling regulated by arginine methylation
    • Boisvert F.M., Chenard C.A., and Richard S. Protein interfaces in signaling regulated by arginine methylation. Sci. STKE 2005 (2005) re2
    • (2005) Sci. STKE , vol.2005
    • Boisvert, F.M.1    Chenard, C.A.2    Richard, S.3
  • 17
    • 0025979549 scopus 로고
    • Identification and expression of a regeneration-specific homeobox gene in the newt limb blastema
    • Brown R., and Brockes J.P. Identification and expression of a regeneration-specific homeobox gene in the newt limb blastema. Development (Cambridge, England) 111 (1991) 489-496
    • (1991) Development (Cambridge, England) , vol.111 , pp. 489-496
    • Brown, R.1    Brockes, J.P.2
  • 22
    • 0033545896 scopus 로고    scopus 로고
    • Rapid release and unusual stability of immunodominant peptide 45-89 from citrullinated myelin basic protein
    • Cao L., Goodin R., Wood D., Moscarello M.A., and Whitaker J.N. Rapid release and unusual stability of immunodominant peptide 45-89 from citrullinated myelin basic protein. Biochemistry 38 (1999) 6157-6163
    • (1999) Biochemistry , vol.38 , pp. 6157-6163
    • Cao, L.1    Goodin, R.2    Wood, D.3    Moscarello, M.A.4    Whitaker, J.N.5
  • 23
    • 33747478288 scopus 로고    scopus 로고
    • Conformation-activity relationship of designed glycopeptides as synthetic probes for the detection of autoantibodies, biomarkers of multiple sclerosis
    • Carotenuto A., D'Ursi A.M., Mulinacci B., Paolini I., Lolli F., Papini A.M., Novellino E., and Rovero P. Conformation-activity relationship of designed glycopeptides as synthetic probes for the detection of autoantibodies, biomarkers of multiple sclerosis. J Med Chem. 49 (2006) 5072-5079
    • (2006) J Med Chem. , vol.49 , pp. 5072-5079
    • Carotenuto, A.1    D'Ursi, A.M.2    Mulinacci, B.3    Paolini, I.4    Lolli, F.5    Papini, A.M.6    Novellino, E.7    Rovero, P.8
  • 24
    • 57049155614 scopus 로고    scopus 로고
    • Casaccia-Bonnefil P. and Shen S. 2008. Histone acetylation and timing of neural progenitor differentiation. In: Encyclopedia of Neuroscience. Edited by U. Windhorst, M. Binder and N. Hirokawa. Heidelberg, Springer Verlag Publishers.
    • Casaccia-Bonnefil P. and Shen S. 2008. Histone acetylation and timing of neural progenitor differentiation. In: Encyclopedia of Neuroscience. Edited by U. Windhorst, M. Binder and N. Hirokawa. Heidelberg, Springer Verlag Publishers.
  • 25
    • 34548493712 scopus 로고    scopus 로고
    • Mechanisms and modulation of neural cell damage induced by oxidative stress
    • Ceccatelli S., Tamm C., Zhang Q., and Chen M. Mechanisms and modulation of neural cell damage induced by oxidative stress. Physiol. Behav. 92 (2007) 87-92
    • (2007) Physiol. Behav. , vol.92 , pp. 87-92
    • Ceccatelli, S.1    Tamm, C.2    Zhang, Q.3    Chen, M.4
  • 26
    • 0034281366 scopus 로고    scopus 로고
    • NG2-positive oligodendrocyte progenitor cells in human brain and multiple sclerosis lesions
    • Chang A., Nishiyama A., Peterson J., Proneas J., and Trapp B.D. NG2-positive oligodendrocyte progenitor cells in human brain and multiple sclerosis lesions. J. Neurosci. 20 (2000) 6404-6412
    • (2000) J. Neurosci. , vol.20 , pp. 6404-6412
    • Chang, A.1    Nishiyama, A.2    Peterson, J.3    Proneas, J.4    Trapp, B.D.5
  • 27
    • 5344272503 scopus 로고    scopus 로고
    • Multiple sclerosis is not an autoimmune disease
    • Chaudhuri A., and Behan P.O. Multiple sclerosis is not an autoimmune disease. Arch. Neurol. 61 (2004) 1610-1612
    • (2004) Arch. Neurol. , vol.61 , pp. 1610-1612
    • Chaudhuri, A.1    Behan, P.O.2
  • 28
    • 16244412634 scopus 로고    scopus 로고
    • Virus-specific and bystander CD8 T cells recruited during virus-induced encephalomyelitis
    • Chen A.M., Khanna N., Stohlman S.A., and Bergmann C.C. Virus-specific and bystander CD8 T cells recruited during virus-induced encephalomyelitis. J. Virol. 79 (2005) 4700-4708
    • (2005) J. Virol. , vol.79 , pp. 4700-4708
    • Chen, A.M.1    Khanna, N.2    Stohlman, S.A.3    Bergmann, C.C.4
  • 32
    • 0027158033 scopus 로고
    • Limiting and repairing the damage in multiple sclerosis
    • Compston A. Limiting and repairing the damage in multiple sclerosis. Schweizerische Medizinische Wochenschrift 123 (1993) 1145-1152
    • (1993) Schweizerische Medizinische Wochenschrift , vol.123 , pp. 1145-1152
    • Compston, A.1
  • 33
    • 0028962622 scopus 로고
    • Brain repair
    • Compston A. Brain repair. J. Intern. Med. 237 (1995) 127-134
    • (1995) J. Intern. Med. , vol.237 , pp. 127-134
    • Compston, A.1
  • 35
    • 29744438031 scopus 로고    scopus 로고
    • Histone deacetylase 1 is essential for oligodendrocyte specification in the zebrafish CNS
    • Cunliffe V.T., and Casaccia-Bonnefil P. Histone deacetylase 1 is essential for oligodendrocyte specification in the zebrafish CNS. Mech. Dev. 123 (2006) 24-30
    • (2006) Mech. Dev. , vol.123 , pp. 24-30
    • Cunliffe, V.T.1    Casaccia-Bonnefil, P.2
  • 36
    • 33748178872 scopus 로고    scopus 로고
    • Differences in susceptibility of MBP charge isomers to digestion by stromelysin-1 (MMP-3) and release of an immunodominant epitope
    • D'Souza C.A., and Moscarello M.A. Differences in susceptibility of MBP charge isomers to digestion by stromelysin-1 (MMP-3) and release of an immunodominant epitope. Neurochem. Res. 31 (2006) 1045-1054
    • (2006) Neurochem. Res. , vol.31 , pp. 1045-1054
    • D'Souza, C.A.1    Moscarello, M.A.2
  • 37
    • 25444524820 scopus 로고    scopus 로고
    • Autocatalytic cleavage of myelin basic protein: an alternative to molecular mimicry
    • D'Souza C.A., Wood D.D., She Y.M., and Moscarello M.A. Autocatalytic cleavage of myelin basic protein: an alternative to molecular mimicry. Biochemistry 44 (2005) 12905-12913
    • (2005) Biochemistry , vol.44 , pp. 12905-12913
    • D'Souza, C.A.1    Wood, D.D.2    She, Y.M.3    Moscarello, M.A.4
  • 38
    • 35348856827 scopus 로고    scopus 로고
    • Global epiproteomic signatures distinguish ES cells from differentiated cells
    • Dai B., and Rasmussen T.P. Global epiproteomic signatures distinguish ES cells from differentiated cells. Stem Cells (2007)
    • (2007) Stem Cells
    • Dai, B.1    Rasmussen, T.P.2
  • 39
    • 0032577868 scopus 로고    scopus 로고
    • Differential expression of human histone deacetylase mRNAs in response to immune cell apoptosis induction by trichostatin A and butyrate
    • Dangond F., and Gullans S.R. Differential expression of human histone deacetylase mRNAs in response to immune cell apoptosis induction by trichostatin A and butyrate. Biochem. Biophys. Res. Commun. 247 (1998) 833-837
    • (1998) Biochem. Biophys. Res. Commun. , vol.247 , pp. 833-837
    • Dangond, F.1    Gullans, S.R.2
  • 40
    • 0037154312 scopus 로고    scopus 로고
    • Transcriptional control: an activating role for arginine methylation
    • Davie J.K., and Dent S.Y. Transcriptional control: an activating role for arginine methylation. Curr. Biol. 12 (2002) R59-61
    • (2002) Curr. Biol. , vol.12
    • Davie, J.K.1    Dent, S.Y.2
  • 42
    • 33646814688 scopus 로고    scopus 로고
    • The role of CD4+ T-cells in the development of MS
    • Delgado S., and Sheremata W.A. The role of CD4+ T-cells in the development of MS. Neurol. Res. 28 (2006) 245-249
    • (2006) Neurol. Res. , vol.28 , pp. 245-249
    • Delgado, S.1    Sheremata, W.A.2
  • 43
    • 15944368623 scopus 로고    scopus 로고
    • PAD: the smoking gun behind arginine methylation signaling?
    • Denman R.B. PAD: the smoking gun behind arginine methylation signaling?. Bioessays 27 (2005) 242-246
    • (2005) Bioessays , vol.27 , pp. 242-246
    • Denman, R.B.1
  • 45
    • 34248230257 scopus 로고    scopus 로고
    • Distinct effector cytokine profiles of memory and naive human B cell subsets and implication in multiple sclerosis
    • Duddy M., Niino M., Adatia F., Hebert S., Freedman M., Atkins H., Kim H.J., and Bar-Or A. Distinct effector cytokine profiles of memory and naive human B cell subsets and implication in multiple sclerosis. J. Immunol. 178 (2007) 6092-6099
    • (2007) J. Immunol. , vol.178 , pp. 6092-6099
    • Duddy, M.1    Niino, M.2    Adatia, F.3    Hebert, S.4    Freedman, M.5    Atkins, H.6    Kim, H.J.7    Bar-Or, A.8
  • 46
    • 34247860705 scopus 로고    scopus 로고
    • A balancing act-making the right choices in anti-inflammatory drug development
    • Elices M.J. A balancing act-making the right choices in anti-inflammatory drug development. Curr. Opin. Investig. Drugs 8 (2007) 362-363
    • (2007) Curr. Opin. Investig. Drugs , vol.8 , pp. 362-363
    • Elices, M.J.1
  • 47
    • 0015504862 scopus 로고
    • A myelin protein fraction extracted with thioethanol
    • Finch P.R., and Moscarello M.A. A myelin protein fraction extracted with thioethanol. Brain Res. 42 (1972) 177-187
    • (1972) Brain Res. , vol.42 , pp. 177-187
    • Finch, P.R.1    Moscarello, M.A.2
  • 48
    • 0034814993 scopus 로고    scopus 로고
    • Histone acetylation beyond promoters: long-range acetylation patterns in the chromatin world
    • Forsberg E.C., and Bresnick E.H. Histone acetylation beyond promoters: long-range acetylation patterns in the chromatin world. Bioessays 23 (2001) 820-830
    • (2001) Bioessays , vol.23 , pp. 820-830
    • Forsberg, E.C.1    Bresnick, E.H.2
  • 50
    • 0032950794 scopus 로고    scopus 로고
    • Identification of autoantibodies associated with myelin damage in multiple sclerosis
    • Genain C.P., Cannella B., Hauser S.L., and Raine C.S. Identification of autoantibodies associated with myelin damage in multiple sclerosis. Nat. Med. 5 (1999) 170-175
    • (1999) Nat. Med. , vol.5 , pp. 170-175
    • Genain, C.P.1    Cannella, B.2    Hauser, S.L.3    Raine, C.S.4
  • 52
    • 0037099468 scopus 로고    scopus 로고
    • Histone modification and replacement in chromatin activation
    • Goll M.G., and Bestor T.H. Histone modification and replacement in chromatin activation. Genes Dev 16 (2002) 1739-1742
    • (2002) Genes Dev , vol.16 , pp. 1739-1742
    • Goll, M.G.1    Bestor, T.H.2
  • 53
    • 0035325163 scopus 로고    scopus 로고
    • Histone acetylation and chromatin remodeling
    • Gregory P.D., Wagner K., and Horz W. Histone acetylation and chromatin remodeling. Exp. Cell Res. 265 (2001) 195-202
    • (2001) Exp. Cell Res. , vol.265 , pp. 195-202
    • Gregory, P.D.1    Wagner, K.2    Horz, W.3
  • 55
    • 2142662186 scopus 로고    scopus 로고
    • Multiple sclerosis
    • Hafler D.A. Multiple sclerosis. J. Clin. Investig. 113 (2004) 788-794
    • (2004) J. Clin. Investig. , vol.113 , pp. 788-794
    • Hafler, D.A.1
  • 57
    • 36849084465 scopus 로고    scopus 로고
    • Linking the epigenetic 'language' of covalent histone modifications to cancer
    • Hake S.B., Xiao A., and Allis C.D. Linking the epigenetic 'language' of covalent histone modifications to cancer. Br. J. Cancer 96 Suppl. (2007) R31-R39
    • (2007) Br. J. Cancer , vol.96 , Issue.SUPPL
    • Hake, S.B.1    Xiao, A.2    Allis, C.D.3
  • 60
  • 62
    • 34548299553 scopus 로고    scopus 로고
    • Reexpression of a developmentally restricted potassium channel in autoimmune demyelination: Kv1.4 is implicated in oligodendroglial proliferation
    • Herrero-Herranz E., Pardo L.A., Bunt G., Gold R., Stuhmer W., and Linker R.A. Reexpression of a developmentally restricted potassium channel in autoimmune demyelination: Kv1.4 is implicated in oligodendroglial proliferation. Am. J. Pathol. 171 (2007) 589-598
    • (2007) Am. J. Pathol. , vol.171 , pp. 589-598
    • Herrero-Herranz, E.1    Pardo, L.A.2    Bunt, G.3    Gold, R.4    Stuhmer, W.5    Linker, R.A.6
  • 63
    • 33748075167 scopus 로고    scopus 로고
    • Symptoms of multiple sclerosis in women in relation to sex steroid exposure
    • Holmqvist P., Wallberg M., Hammar M., Landtblom A.M., and Brynhildsen J. Symptoms of multiple sclerosis in women in relation to sex steroid exposure. Maturitas 54 (2006) 149-153
    • (2006) Maturitas , vol.54 , pp. 149-153
    • Holmqvist, P.1    Wallberg, M.2    Hammar, M.3    Landtblom, A.M.4    Brynhildsen, J.5
  • 64
    • 9344252804 scopus 로고    scopus 로고
    • Histone deacetylase inhibition-mediated neuronal differentiation of multipotent adult neural progenitor cells
    • Hsieh J., Nakashima K., Kuwabara T., Mejia E., and Gage F.H. Histone deacetylase inhibition-mediated neuronal differentiation of multipotent adult neural progenitor cells. Proc. Natl. Acad. Sci. U. S. A. 101 (2004) 16659-16664
    • (2004) Proc. Natl. Acad. Sci. U. S. A. , vol.101 , pp. 16659-16664
    • Hsieh, J.1    Nakashima, K.2    Kuwabara, T.3    Mejia, E.4    Gage, F.H.5
  • 65
    • 31344446119 scopus 로고    scopus 로고
    • Histone deacetylase 2-mediated deacetylation of the glucocorticoid receptor enables NF-kappaB suppression
    • Ito K., Yamamura S., Essilfie-Quaye S., Cosio B., Ito M., Barnes P.J., and Adcock I.M. Histone deacetylase 2-mediated deacetylation of the glucocorticoid receptor enables NF-kappaB suppression. J. Exp. Med. 203 (2006) 7-13
    • (2006) J. Exp. Med. , vol.203 , pp. 7-13
    • Ito, K.1    Yamamura, S.2    Essilfie-Quaye, S.3    Cosio, B.4    Ito, M.5    Barnes, P.J.6    Adcock, I.M.7
  • 67
    • 0036799650 scopus 로고    scopus 로고
    • Multiple sclerosis: re-expression of a developmental pathway that restricts oligodendrocyte maturation
    • John G.R., Shankar S.L., Shafit-Zagardo B., Massimi A., Lee S.C., Raine C.S., and Brosnan C.F. Multiple sclerosis: re-expression of a developmental pathway that restricts oligodendrocyte maturation. Nat. Med. 8 (2002) 1115-1121
    • (2002) Nat. Med. , vol.8 , pp. 1115-1121
    • John, G.R.1    Shankar, S.L.2    Shafit-Zagardo, B.3    Massimi, A.4    Lee, S.C.5    Raine, C.S.6    Brosnan, C.F.7
  • 68
    • 4143098311 scopus 로고    scopus 로고
    • CBP and p300: HATs for different occasions
    • Kalkhoven E. CBP and p300: HATs for different occasions. Biochem. Pharmacol. 68 (2004) 1145-1155
    • (2004) Biochem. Pharmacol. , vol.68 , pp. 1145-1155
    • Kalkhoven, E.1
  • 69
    • 33847095134 scopus 로고    scopus 로고
    • Complex disease, gender and epigenetics
    • Kaminsky Z., Wang S.C., and Petronis A. Complex disease, gender and epigenetics. Ann. Med. 38 (2006) 530-544
    • (2006) Ann. Med. , vol.38 , pp. 530-544
    • Kaminsky, Z.1    Wang, S.C.2    Petronis, A.3
  • 70
    • 33748908067 scopus 로고    scopus 로고
    • Protecting axonal degeneration by increasing nicotinamide adenine dinucleotide levels in experimental autoimmune encephalomyelitis models
    • Kaneko S., Wang J., Kaneko M., Yiu G., Hurrell J.M., Chitnis T., Khoury S.J., and He Z. Protecting axonal degeneration by increasing nicotinamide adenine dinucleotide levels in experimental autoimmune encephalomyelitis models. J. Neurosci. 26 (2006) 9794-9804
    • (2006) J. Neurosci. , vol.26 , pp. 9794-9804
    • Kaneko, S.1    Wang, J.2    Kaneko, M.3    Yiu, G.4    Hurrell, J.M.5    Chitnis, T.6    Khoury, S.J.7    He, Z.8
  • 72
    • 33846798072 scopus 로고    scopus 로고
    • Niche-to-niche migration of bone-marrow-derived cells
    • Kaplan R.N., Psaila B., and Lyden D. Niche-to-niche migration of bone-marrow-derived cells. Trends Mol. Med. 13 (2007) 72-81
    • (2007) Trends Mol. Med. , vol.13 , pp. 72-81
    • Kaplan, R.N.1    Psaila, B.2    Lyden, D.3
  • 73
    • 33748510173 scopus 로고    scopus 로고
    • Innate immunity in multiple sclerosis: myeloid dendritic cells in secondary progressive multiple sclerosis are activated and drive a proinflammatory immune response
    • Karni A., Abraham M., Monsonego A., Cai G., Freeman G.J., Hafler D., Khoury S.J., and Weiner H.L. Innate immunity in multiple sclerosis: myeloid dendritic cells in secondary progressive multiple sclerosis are activated and drive a proinflammatory immune response. J. Immunol. 177 (2006) 4196-4202
    • (2006) J. Immunol. , vol.177 , pp. 4196-4202
    • Karni, A.1    Abraham, M.2    Monsonego, A.3    Cai, G.4    Freeman, G.J.5    Hafler, D.6    Khoury, S.J.7    Weiner, H.L.8
  • 74
    • 0033024388 scopus 로고    scopus 로고
    • TNF accelerates the onset but does not alter the incidence and severity of myelin basic protein-induced experimental autoimmune encephalomyelitis
    • Kassiotis G., Pasparakis M., Kollias G., and Probert L. TNF accelerates the onset but does not alter the incidence and severity of myelin basic protein-induced experimental autoimmune encephalomyelitis. Eur. J. Immunol. 29 (1999) 774-780
    • (1999) Eur. J. Immunol. , vol.29 , pp. 774-780
    • Kassiotis, G.1    Pasparakis, M.2    Kollias, G.3    Probert, L.4
  • 75
    • 34249687536 scopus 로고    scopus 로고
    • B cells: no longer the nondominant arm of multiple sclerosis
    • Klawiter E.C., and Cross A.H. B cells: no longer the nondominant arm of multiple sclerosis. Curr. Neurol. Neurosci. Rep. 7 (2007) 231-238
    • (2007) Curr. Neurol. Neurosci. Rep. , vol.7 , pp. 231-238
    • Klawiter, E.C.1    Cross, A.H.2
  • 76
    • 33947513027 scopus 로고    scopus 로고
    • Regulation of histone methylation by demethylimination and demethylation
    • Klose R.J., and Zhang Y. Regulation of histone methylation by demethylimination and demethylation. Nat. Rev. Mol. Cell Biol. 8 (2007) 307-318
    • (2007) Nat. Rev. Mol. Cell Biol. , vol.8 , pp. 307-318
    • Klose, R.J.1    Zhang, Y.2
  • 78
    • 34147154707 scopus 로고    scopus 로고
    • Treatment with interferon beta-1b delays conversion to clinically definite and McDonald MS in patients with clinically isolated syndromes
    • (author reply 1163-1164)
    • Koch M.W., Mostert J.P., de Vries J.J., and De Keyser J. Treatment with interferon beta-1b delays conversion to clinically definite and McDonald MS in patients with clinically isolated syndromes. Neurology 68 (2007) 1163 (author reply 1163-1164)
    • (2007) Neurology , vol.68 , pp. 1163
    • Koch, M.W.1    Mostert, J.P.2    de Vries, J.J.3    De Keyser, J.4
  • 79
    • 21444447035 scopus 로고    scopus 로고
    • Experimental demyelination caused by primary oligodendrocyte dystrophy. Regional distribution of the lesions in the nervous system of mice [corrected]
    • Komoly S. Experimental demyelination caused by primary oligodendrocyte dystrophy. Regional distribution of the lesions in the nervous system of mice [corrected]. Ideggyogyaszati Szemle 58 (2005) 40-43
    • (2005) Ideggyogyaszati Szemle , vol.58 , pp. 40-43
    • Komoly, S.1
  • 80
    • 9944266165 scopus 로고    scopus 로고
    • Chromatin remodeling and histone modification in the conversion of oligodendrocyte precursors to neural stem cells
    • Kondo T., and Raff M. Chromatin remodeling and histone modification in the conversion of oligodendrocyte precursors to neural stem cells. Genes Dev. 18 (2004) 2963-2972
    • (2004) Genes Dev. , vol.18 , pp. 2963-2972
    • Kondo, T.1    Raff, M.2
  • 81
    • 0041589180 scopus 로고    scopus 로고
    • Neuropathology of multiple sclerosis-new concepts
    • Kornek B., and Lassmann H. Neuropathology of multiple sclerosis-new concepts. Brain Res Bull 61 (2003) 321-326
    • (2003) Brain Res Bull , vol.61 , pp. 321-326
    • Kornek, B.1    Lassmann, H.2
  • 83
    • 0036532202 scopus 로고    scopus 로고
    • Histone methylation in transcriptional control
    • Kouzarides T. Histone methylation in transcriptional control. Curr. Opin. Genet. Dev. 12 (2002) 198-209
    • (2002) Curr. Opin. Genet. Dev. , vol.12 , pp. 198-209
    • Kouzarides, T.1
  • 84
    • 33847076849 scopus 로고    scopus 로고
    • Chromatin modifications and their function
    • Kouzarides T. Chromatin modifications and their function. Cell 128 (2007) 693-705
    • (2007) Cell , vol.128 , pp. 693-705
    • Kouzarides, T.1
  • 85
    • 11144277879 scopus 로고    scopus 로고
    • A crack in histone lysine methylation
    • Kubicek S., and Jenuwein T. A crack in histone lysine methylation. Cell 119 (2004) 903-906
    • (2004) Cell , vol.119 , pp. 903-906
    • Kubicek, S.1    Jenuwein, T.2
  • 87
    • 0036591878 scopus 로고    scopus 로고
    • The many faces of histone lysine methylation
    • Lachner M., and Jenuwein T. The many faces of histone lysine methylation. Curr. Opin. Cell Biol. 14 (2002) 286-298
    • (2002) Curr. Opin. Cell Biol. , vol.14 , pp. 286-298
    • Lachner, M.1    Jenuwein, T.2
  • 88
    • 0026277324 scopus 로고
    • CpG methylation of an endogenous retroviral enhancer inhibits transcription factor binding and activity
    • Lamb B.T., Satyamoorthy K., Li L., Solter D., and Howe C.C. CpG methylation of an endogenous retroviral enhancer inhibits transcription factor binding and activity. Gene Exp. 1 (1991) 185-196
    • (1991) Gene Exp. , vol.1 , pp. 185-196
    • Lamb, B.T.1    Satyamoorthy, K.2    Li, L.3    Solter, D.4    Howe, C.C.5
  • 89
    • 0027317616 scopus 로고
    • Deimination of human myelin basic protein by a peptidylarginine deiminase from bovine brain
    • Lamensa J.W., and Moscarello M.A. Deimination of human myelin basic protein by a peptidylarginine deiminase from bovine brain. J. Neurochem. 61 (1993) 987-996
    • (1993) J. Neurochem. , vol.61 , pp. 987-996
    • Lamensa, J.W.1    Moscarello, M.A.2
  • 90
    • 0032526198 scopus 로고    scopus 로고
    • Immunopathology of multiple sclerosis: report on an international meeting held at the Institute of Neurology of the University of Vienna
    • Lassmann H., Raine C.S., Antel J., and Prineas J.W. Immunopathology of multiple sclerosis: report on an international meeting held at the Institute of Neurology of the University of Vienna. J. Neuroimmunol. 86 (1998) 213-217
    • (1998) J. Neuroimmunol. , vol.86 , pp. 213-217
    • Lassmann, H.1    Raine, C.S.2    Antel, J.3    Prineas, J.W.4
  • 91
    • 33847305516 scopus 로고    scopus 로고
    • Is there a role for neurotrophins in the pathology of multiple sclerosis?
    • Linker R., Lee D.H., Siglienti I., and Gold R. Is there a role for neurotrophins in the pathology of multiple sclerosis?. J. Neurol. 254 Suppl. 1 (2007) I33-I40
    • (2007) J. Neurol. , vol.254 , Issue.SUPPL. 1
    • Linker, R.1    Lee, D.H.2    Siglienti, I.3    Gold, R.4
  • 92
    • 0344013131 scopus 로고    scopus 로고
    • Oligodendrocyte process outgrowth in vitro is modulated by epigenetic regulation of cytoskeletal severing proteins
    • Liu A., Muggironi M., Marin-Husstege M., and Casaccia-Bonnefil P. Oligodendrocyte process outgrowth in vitro is modulated by epigenetic regulation of cytoskeletal severing proteins. Glia. 44 (2003) 264-274
    • (2003) Glia. , vol.44 , pp. 264-274
    • Liu, A.1    Muggironi, M.2    Marin-Husstege, M.3    Casaccia-Bonnefil, P.4
  • 93
  • 94
    • 33750213516 scopus 로고    scopus 로고
    • A molecular insight of Hes5-dependent inhibition of myelin gene expression: old partners and new players
    • Liu A., Li J., Marin-Husstege M., Kageyama R., Fan Y., Gelinas C., and Casaccia-Bonnefil P. A molecular insight of Hes5-dependent inhibition of myelin gene expression: old partners and new players. EMBO J. 25 (2006) 4833-4842
    • (2006) EMBO J. , vol.25 , pp. 4833-4842
    • Liu, A.1    Li, J.2    Marin-Husstege, M.3    Kageyama, R.4    Fan, Y.5    Gelinas, C.6    Casaccia-Bonnefil, P.7
  • 97
    • 0342906187 scopus 로고    scopus 로고
    • Heterogeneity of multiple sclerosis lesions: implications for the pathogenesis of demyelination
    • Lucchinetti C., Bruck W., Parisi J., Scheithauer B., Rodriguez M., and Lassmann H. Heterogeneity of multiple sclerosis lesions: implications for the pathogenesis of demyelination. Ann. Neurol. 47 (2000) 707-717
    • (2000) Ann. Neurol. , vol.47 , pp. 707-717
    • Lucchinetti, C.1    Bruck, W.2    Parisi, J.3    Scheithauer, B.4    Rodriguez, M.5    Lassmann, H.6
  • 98
    • 33744966338 scopus 로고    scopus 로고
    • The pathogenesis of multiple sclerosis: relating human pathology to experimental studies
    • Ludwin S.K. The pathogenesis of multiple sclerosis: relating human pathology to experimental studies. J. Neuropathol. Exp. Neurol. 65 (2006) 305-318
    • (2006) J. Neuropathol. Exp. Neurol. , vol.65 , pp. 305-318
    • Ludwin, S.K.1
  • 100
    • 35448949103 scopus 로고    scopus 로고
    • Inhibition of histone deacetylase activity induces developmental plasticity in oligodendrocyte precursor cells
    • Lyssiotis C.A., Walker J., Wu C., Kondo T., Schultz P.G., and Wu X. Inhibition of histone deacetylase activity induces developmental plasticity in oligodendrocyte precursor cells. Proc. Natl. Acad. Sci. U. S. A. 104 (2007) 14982-14987
    • (2007) Proc. Natl. Acad. Sci. U. S. A. , vol.104 , pp. 14982-14987
    • Lyssiotis, C.A.1    Walker, J.2    Wu, C.3    Kondo, T.4    Schultz, P.G.5    Wu, X.6
  • 101
    • 33749187336 scopus 로고    scopus 로고
    • Increased "vigilance" of antioxidant mechanisms in neural stem cells potentiates their capability to resist oxidative stress
    • Madhavan L., Ourednik V., and Ourednik J. Increased "vigilance" of antioxidant mechanisms in neural stem cells potentiates their capability to resist oxidative stress. Stem Cells 24 (2006) 2110-2119
    • (2006) Stem Cells , vol.24 , pp. 2110-2119
    • Madhavan, L.1    Ourednik, V.2    Ourednik, J.3
  • 102
    • 0036897351 scopus 로고    scopus 로고
    • Histone deacetylase activity is necessary for oligodendrocyte lineage progression
    • Marin-Husstege M., Muggironi M., Liu A., and Casaccia-Bonnefil P. Histone deacetylase activity is necessary for oligodendrocyte lineage progression. J. Neurosci. 22 (2002) 10333-10345
    • (2002) J. Neurosci. , vol.22 , pp. 10333-10345
    • Marin-Husstege, M.1    Muggironi, M.2    Liu, A.3    Casaccia-Bonnefil, P.4
  • 103
    • 2442494039 scopus 로고    scopus 로고
    • Attenuation of experimental autoimmune encephalomyelitis and nonimmune demyelination by IFN-beta plus vitamin B12: treatment to modify notch-1/sonic hedgehog balance
    • Mastronardi F.G., Min W., Wang H., Winer S., Dosch M., Boggs J.M., and Moscarello M.A. Attenuation of experimental autoimmune encephalomyelitis and nonimmune demyelination by IFN-beta plus vitamin B12: treatment to modify notch-1/sonic hedgehog balance. J. Immunol. 172 (2004) 6418-6426
    • (2004) J. Immunol. , vol.172 , pp. 6418-6426
    • Mastronardi, F.G.1    Min, W.2    Wang, H.3    Winer, S.4    Dosch, M.5    Boggs, J.M.6    Moscarello, M.A.7
  • 104
    • 20344365607 scopus 로고    scopus 로고
    • Molecules affecting myelin stability: a novel hypothesis regarding the pathogenesis of multiple sclerosis
    • Mastronardi F.G., and Moscarello M.A. Molecules affecting myelin stability: a novel hypothesis regarding the pathogenesis of multiple sclerosis. J. Neurosci. Res. 80 (2005) 301-308
    • (2005) J. Neurosci. Res. , vol.80 , pp. 301-308
    • Mastronardi, F.G.1    Moscarello, M.A.2
  • 105
    • 34447334574 scopus 로고    scopus 로고
    • Peptidyl argininedeiminase 2 CpG island in multiple sclerosis white matter is hypomethylated
    • Mastronardi F.G., Noor A., Wood D.D., Paton T., and Moscarello M.A. Peptidyl argininedeiminase 2 CpG island in multiple sclerosis white matter is hypomethylated. J. Neurosci. Res. 85 (2007) 2006-2016
    • (2007) J. Neurosci. Res. , vol.85 , pp. 2006-2016
    • Mastronardi, F.G.1    Noor, A.2    Wood, D.D.3    Paton, T.4    Moscarello, M.A.5
  • 107
    • 33750957133 scopus 로고    scopus 로고
    • Increased citrullination of histone [3H] in multiple sclerosis brain and animal models of demyelination: a role for tumor necrosis factor-induced peptidylarginine deiminase 4 translocation
    • Mastronardi F.G., Wood D.D., Mei J., Raijmakers R., Tseveleki V., Dosch H.M., Probert L., Casaccia-Bonnefil P., and Moscarello M.A. Increased citrullination of histone [3H] in multiple sclerosis brain and animal models of demyelination: a role for tumor necrosis factor-induced peptidylarginine deiminase 4 translocation. J. Neurosci. 26 (2006) 11387-11396
    • (2006) J. Neurosci. , vol.26 , pp. 11387-11396
    • Mastronardi, F.G.1    Wood, D.D.2    Mei, J.3    Raijmakers, R.4    Tseveleki, V.5    Dosch, H.M.6    Probert, L.7    Casaccia-Bonnefil, P.8    Moscarello, M.A.9
  • 108
    • 33646787755 scopus 로고    scopus 로고
    • The role of CD8+ T-cells in lesion formation and axonal dysfunction in multiple sclerosis
    • McDole J., Johnson A.J., and Pirko I. The role of CD8+ T-cells in lesion formation and axonal dysfunction in multiple sclerosis. Neurol. Res. 28 (2006) 256-261
    • (2006) Neurol. Res. , vol.28 , pp. 256-261
    • McDole, J.1    Johnson, A.J.2    Pirko, I.3
  • 110
    • 0028835697 scopus 로고
    • Reactivity of normal T-cell lines to MBP isolated from normal and multiple sclerosis white matter
    • McLaurin J., Hafler D., and Antel J.P. Reactivity of normal T-cell lines to MBP isolated from normal and multiple sclerosis white matter. J. Neurol. Sci. 128 (1995) 205-211
    • (1995) J. Neurol. Sci. , vol.128 , pp. 205-211
    • McLaurin, J.1    Hafler, D.2    Antel, J.P.3
  • 111
    • 0141427768 scopus 로고    scopus 로고
    • Clearance of Theiler's virus infection depends on the ability to generate a CD8+ T cell response against a single immunodominant viral peptide
    • Mendez-Fernandez Y.V., Johnson A.J., Rodriguez M., and Pease L.R. Clearance of Theiler's virus infection depends on the ability to generate a CD8+ T cell response against a single immunodominant viral peptide. Eur. J. Immunol. 33 (2003) 2501-2510
    • (2003) Eur. J. Immunol. , vol.33 , pp. 2501-2510
    • Mendez-Fernandez, Y.V.1    Johnson, A.J.2    Rodriguez, M.3    Pease, L.R.4
  • 113
    • 34249083199 scopus 로고    scopus 로고
    • Sirtuins in mammals: insights into their biological function
    • Michan S., and Sinclair D. Sirtuins in mammals: insights into their biological function. Biochem. J. 404 (2007) 1-13
    • (2007) Biochem. J. , vol.404 , pp. 1-13
    • Michan, S.1    Sinclair, D.2
  • 114
    • 3042566927 scopus 로고    scopus 로고
    • The histone deacetylase inhibitor Trichostatin A modulates CD4+ T cell responses
    • Moreira J.M., Scheipers P., and Sorensen P. The histone deacetylase inhibitor Trichostatin A modulates CD4+ T cell responses. BMC Cancer 3 (2003) 30
    • (2003) BMC Cancer , vol.3 , pp. 30
    • Moreira, J.M.1    Scheipers, P.2    Sorensen, P.3
  • 115
    • 0022630746 scopus 로고
    • The role of charge microheterogeneity of basic protein in the formation and maintenance of the multilayered structure of myelin: a possible role in multiple sclerosis
    • Moscarello M.A., Brady G.W., Fein D.B., Wood D.D., and Cruz T.F. The role of charge microheterogeneity of basic protein in the formation and maintenance of the multilayered structure of myelin: a possible role in multiple sclerosis. J. Neurosci. Res. 15 (1986) 87-99
    • (1986) J. Neurosci. Res. , vol.15 , pp. 87-99
    • Moscarello, M.A.1    Brady, G.W.2    Fein, D.B.3    Wood, D.D.4    Cruz, T.F.5
  • 116
    • 33846914679 scopus 로고    scopus 로고
    • The role of citrullinated proteins suggests a novel mechanism in the pathogenesis of multiple sclerosis
    • Moscarello M.A., Mastronardi F.G., and Wood D.D. The role of citrullinated proteins suggests a novel mechanism in the pathogenesis of multiple sclerosis. Neurochem. Res. 32 (2007) 251-256
    • (2007) Neurochem. Res. , vol.32 , pp. 251-256
    • Moscarello, M.A.1    Mastronardi, F.G.2    Wood, D.D.3
  • 117
    • 0036316687 scopus 로고    scopus 로고
    • Peptidylarginine deiminase: a candidate factor in demyelinating disease
    • Moscarello M.A., Pritzker L., Mastronardi F.G., and Wood D.D. Peptidylarginine deiminase: a candidate factor in demyelinating disease. J. Neurochem. 81 (2002) 335-343
    • (2002) J. Neurochem. , vol.81 , pp. 335-343
    • Moscarello, M.A.1    Pritzker, L.2    Mastronardi, F.G.3    Wood, D.D.4
  • 119
    • 33749852275 scopus 로고    scopus 로고
    • The role of HLA promoters in autoimmunity
    • Muller-Hilke B., and Mitchison N.A. The role of HLA promoters in autoimmunity. Curr. Pharm. Des. 12 (2006) 3743-3752
    • (2006) Curr. Pharm. Des. , vol.12 , pp. 3743-3752
    • Muller-Hilke, B.1    Mitchison, N.A.2
  • 120
    • 0034956124 scopus 로고    scopus 로고
    • Spontaneous remyelination following extensive demyelination is associated with improved neurological function in a viral model of multiple sclerosis
    • Murray P.D., McGavern D.B., Sathornsumetee S., and Rodriguez M. Spontaneous remyelination following extensive demyelination is associated with improved neurological function in a viral model of multiple sclerosis. Brain 124 (2001) 1403-1416
    • (2001) Brain , vol.124 , pp. 1403-1416
    • Murray, P.D.1    McGavern, D.B.2    Sathornsumetee, S.3    Rodriguez, M.4
  • 121
    • 33645210449 scopus 로고    scopus 로고
    • Deimination of membrane-bound myelin basic protein in multiple sclerosis exposes an immunodominant epitope
    • Musse A.A., Boggs J.M., and Harauz G. Deimination of membrane-bound myelin basic protein in multiple sclerosis exposes an immunodominant epitope. Proc. Natl. Acad. Sci. U. S. A. 103 (2006) 4422-4427
    • (2006) Proc. Natl. Acad. Sci. U. S. A. , vol.103 , pp. 4422-4427
    • Musse, A.A.1    Boggs, J.M.2    Harauz, G.3
  • 122
    • 34248681263 scopus 로고    scopus 로고
    • Molecular "negativity" may underlie multiple sclerosis: role of the myelin basic protein family in the pathogenesis of MS
    • Musse A.A., and Harauz G. Molecular "negativity" may underlie multiple sclerosis: role of the myelin basic protein family in the pathogenesis of MS. Int Rev Neurobiol. 79 (2007) 149-172
    • (2007) Int Rev Neurobiol. , vol.79 , pp. 149-172
    • Musse, A.A.1    Harauz, G.2
  • 124
    • 0027340084 scopus 로고
    • Regulation of Epstein-Barr virus BamHI-H divergent promoter by DNA methylation
    • Nonkwelo C.B., and Long W.K. Regulation of Epstein-Barr virus BamHI-H divergent promoter by DNA methylation. Virology 197 (1993) 205-215
    • (1993) Virology , vol.197 , pp. 205-215
    • Nonkwelo, C.B.1    Long, W.K.2
  • 125
    • 33748488245 scopus 로고    scopus 로고
    • Human cytomegalovirus inhibits neuronal differentiation and induces apoptosis in human neural precursor cells
    • Odeberg J., Wolmer N., Falci S., Westgren M., Seiger A., and Soderberg-Naucler C. Human cytomegalovirus inhibits neuronal differentiation and induces apoptosis in human neural precursor cells. J. Virol. 80 (2006) 8929-8939
    • (2006) J. Virol. , vol.80 , pp. 8929-8939
    • Odeberg, J.1    Wolmer, N.2    Falci, S.3    Westgren, M.4    Seiger, A.5    Soderberg-Naucler, C.6
  • 126
    • 21744439328 scopus 로고    scopus 로고
    • Biological implications of cell fusion
    • Ogle B.M., Cascalho M., and Platt J.L. Biological implications of cell fusion. Nat. Rev. 6 (2005) 567-575
    • (2005) Nat. Rev. , vol.6 , pp. 567-575
    • Ogle, B.M.1    Cascalho, M.2    Platt, J.L.3
  • 127
    • 0027537296 scopus 로고
    • CpG methylation inactivates the promoter activity of the human retinoblastoma tumorsuppressor gene
    • Ohtani-Fujita N., Fujita T., Aoike A., Osifchin N.E., Robbins P.D., and Sakai T. CpG methylation inactivates the promoter activity of the human retinoblastoma tumorsuppressor gene. Oncogene 8 (1993) 1063-1067
    • (1993) Oncogene , vol.8 , pp. 1063-1067
    • Ohtani-Fujita, N.1    Fujita, T.2    Aoike, A.3    Osifchin, N.E.4    Robbins, P.D.5    Sakai, T.6
  • 128
    • 33646687713 scopus 로고    scopus 로고
    • New era for MS treatment, Severe setback when it comes to enthusiasm-highly effective agent caused serious adverse effects
    • Olsson T. New era for MS treatment, Severe setback when it comes to enthusiasm-highly effective agent caused serious adverse effects. Lakartidningen 103 (2006) 1282-1283
    • (2006) Lakartidningen , vol.103 , pp. 1282-1283
    • Olsson, T.1
  • 129
    • 33845418030 scopus 로고    scopus 로고
    • Protein arginine methylation: cellular functions and methods of analysis
    • Pahlich S., Zakaryan R.P., and Gehring H. Protein arginine methylation: cellular functions and methods of analysis. Biochim. Biophys. Acta 1764 (2006) 1890-1903
    • (2006) Biochim. Biophys. Acta , vol.1764 , pp. 1890-1903
    • Pahlich, S.1    Zakaryan, R.P.2    Gehring, H.3
  • 130
    • 6344222803 scopus 로고    scopus 로고
    • Human SWI/SNF-associated PRMT5 methylates histone H3 arginine 8 and negatively regulates expression of ST7 and NM23 tumor suppressor genes
    • Pal S., Vishwanath S.N., Erdjument-Bromage H., Tempst P., and Sif S. Human SWI/SNF-associated PRMT5 methylates histone H3 arginine 8 and negatively regulates expression of ST7 and NM23 tumor suppressor genes. Mol. Cell Biol. 24 (2004) 9630-9645
    • (2004) Mol. Cell Biol. , vol.24 , pp. 9630-9645
    • Pal, S.1    Vishwanath, S.N.2    Erdjument-Bromage, H.3    Tempst, P.4    Sif, S.5
  • 132
    • 33745752370 scopus 로고    scopus 로고
    • Epigenetics and twins: three variations on the theme
    • Petronis A. Epigenetics and twins: three variations on the theme. Trends Genet. 22 (2006) 347-350
    • (2006) Trends Genet. , vol.22 , pp. 347-350
    • Petronis, A.1
  • 133
    • 33947095512 scopus 로고    scopus 로고
    • The pathology of MS: new insights and potential clinical applications
    • Pittock S.J., and Lucchinetti C.F. The pathology of MS: new insights and potential clinical applications. Neurologist 13 (2007) 45-56
    • (2007) Neurologist , vol.13 , pp. 45-56
    • Pittock, S.J.1    Lucchinetti, C.F.2
  • 134
    • 33644619154 scopus 로고    scopus 로고
    • The multiple sclerosis trait and the development of multiple sclerosis: genetic vulnerability and environmental effect
    • Poser C.M. The multiple sclerosis trait and the development of multiple sclerosis: genetic vulnerability and environmental effect. Clin. Neurol. Neurosurg. 108 (2006) 227-233
    • (2006) Clin. Neurol. Neurosurg. , vol.108 , pp. 227-233
    • Poser, C.M.1
  • 135
    • 0018410045 scopus 로고
    • Remyelination in multiple sclerosis
    • Prineas J.W., and Connell F. Remyelination in multiple sclerosis. Ann. Neurol. 5 (1979) 22-31
    • (1979) Ann. Neurol. , vol.5 , pp. 22-31
    • Prineas, J.W.1    Connell, F.2
  • 136
    • 0021647150 scopus 로고
    • Continual breakdown and regeneration of myelin in multiple sclerosis plaques
    • Prineas J.W., Kwon E.E., ChoES, and Sharer L.R. Continual breakdown and regeneration of myelin in multiple sclerosis plaques. Ann. N. Y. Acad. Sci. 436 (1984) 11-32
    • (1984) Ann. N. Y. Acad. Sci. , vol.436 , pp. 11-32
    • Prineas, J.W.1    Kwon, E.E.2    ChoES3    Sharer, L.R.4
  • 138
    • 0034625091 scopus 로고    scopus 로고
    • Deimination of myelin basic protein 1. Effect of deimination of arginyl residues of myelin basic protein on its structure and susceptibility to digestion by cathepsin D
    • Pritzker L.B., Joshi S., Gowan J.J., Harauz G., and Moscarello M.A. Deimination of myelin basic protein 1. Effect of deimination of arginyl residues of myelin basic protein on its structure and susceptibility to digestion by cathepsin D. Biochemistry 39 (2000) 5374-5381
    • (2000) Biochemistry , vol.39 , pp. 5374-5381
    • Pritzker, L.B.1    Joshi, S.2    Gowan, J.J.3    Harauz, G.4    Moscarello, M.A.5
  • 139
    • 33947693747 scopus 로고    scopus 로고
    • On the use of the word 'epigenetic'
    • Ptashne M. On the use of the word 'epigenetic'. Curr. Biol. 17 (2007) R233-236
    • (2007) Curr. Biol. , vol.17
    • Ptashne, M.1
  • 141
    • 0024245664 scopus 로고
    • On the immunopathology of plaque development and repair in multiple sclerosis
    • Raine C.S., and Scheinberg L.C. On the immunopathology of plaque development and repair in multiple sclerosis. J Neuroimmunol. 20 (1988) 189-201
    • (1988) J Neuroimmunol. , vol.20 , pp. 189-201
    • Raine, C.S.1    Scheinberg, L.C.2
  • 142
    • 0027173943 scopus 로고
    • Multiple sclerosis: remyelination in acute lesions
    • Raine C.S., and Wu E. Multiple sclerosis: remyelination in acute lesions. J Neuropathol Exp Neurol. 52 (1993) 199-204
    • (1993) J Neuropathol Exp Neurol. , vol.52 , pp. 199-204
    • Raine, C.S.1    Wu, E.2
  • 144
    • 0035370439 scopus 로고    scopus 로고
    • Histone methylation versus histone acetylation: new insights into epigenetic regulation
    • Rice J.C., and Allis C.D. Histone methylation versus histone acetylation: new insights into epigenetic regulation. Curr. Opin. Cell Biol. 13 (2001) 263-273
    • (2001) Curr. Opin. Cell Biol. , vol.13 , pp. 263-273
    • Rice, J.C.1    Allis, C.D.2
  • 145
    • 0037108457 scopus 로고    scopus 로고
    • Chromatin methylation: who's on first?
    • Richards E.J. Chromatin methylation: who's on first?. Curr. Biol. 12 (2002) R694-695
    • (2002) Curr. Biol. , vol.12
    • Richards, E.J.1
  • 148
    • 33846019277 scopus 로고    scopus 로고
    • Methylation of lysine 4 on histone H3: intricacy of writing and reading a single epigenetic mark
    • Ruthenburg A.J., Allis C.D., and Wysocka J. Methylation of lysine 4 on histone H3: intricacy of writing and reading a single epigenetic mark. Mol. Cell 25 (2007) 15-30
    • (2007) Mol. Cell , vol.25 , pp. 15-30
    • Ruthenburg, A.J.1    Allis, C.D.2    Wysocka, J.3
  • 149
    • 0024293519 scopus 로고
    • Position dependent expression of a homeobox gene transcript in relation to amphibian limb regeneration
    • Savard P., Gates P.B., and Brockes J.P. Position dependent expression of a homeobox gene transcript in relation to amphibian limb regeneration. EMBO J. 7 (1988) 4275-4282
    • (1988) EMBO J. , vol.7 , pp. 4275-4282
    • Savard, P.1    Gates, P.B.2    Brockes, J.P.3
  • 150
    • 0029063231 scopus 로고
    • Differential regulation of Hox C6 in the appendages of adult urodeles and anurans
    • Savard P., and Tremblay M. Differential regulation of Hox C6 in the appendages of adult urodeles and anurans. J. Mol. Biol. 249 (1995) 879-889
    • (1995) J. Mol. Biol. , vol.249 , pp. 879-889
    • Savard, P.1    Tremblay, M.2
  • 151
    • 33744457667 scopus 로고    scopus 로고
    • A new era in the genetic analysis of multiple sclerosis
    • Sawcer S. A new era in the genetic analysis of multiple sclerosis. Curr. Opin. Neurol. 19 (2006) 237-241
    • (2006) Curr. Opin. Neurol. , vol.19 , pp. 237-241
    • Sawcer, S.1
  • 152
    • 33645166049 scopus 로고    scopus 로고
    • Multiple sclerosis: light at the end of the tunnel
    • Sawcer S., and Compston A. Multiple sclerosis: light at the end of the tunnel. Eur. J. Hum. Genet. 14 (2006) 257-258
    • (2006) Eur. J. Hum. Genet. , vol.14 , pp. 257-258
    • Sawcer, S.1    Compston, A.2
  • 154
    • 22344446199 scopus 로고    scopus 로고
    • Histone modifications affect timing of oligodendrocyte progenitor differentiation in the developing rat brain
    • Shen S., Li J., and Casaccia-Bonnefil P. Histone modifications affect timing of oligodendrocyte progenitor differentiation in the developing rat brain. J. Cell Biol. 169 (2005) 577-589
    • (2005) J. Cell Biol. , vol.169 , pp. 577-589
    • Shen, S.1    Li, J.2    Casaccia-Bonnefil, P.3
  • 155
    • 45949109126 scopus 로고    scopus 로고
    • Post-translational modifications of nucleosomal histones in oligodendrocyte lineage cells in development and disease
    • Shen S., and Casaccia-Bonnefil P. Post-translational modifications of nucleosomal histones in oligodendrocyte lineage cells in development and disease. J. Mol. Neurosci. 35 (2008) 13-22
    • (2008) J. Mol. Neurosci. , vol.35 , pp. 13-22
    • Shen, S.1    Casaccia-Bonnefil, P.2
  • 156
    • 38949136675 scopus 로고    scopus 로고
    • Epigenetic memory loss in aging oligodendrocytes in the corpus callosum
    • Shen S., Liu A., Li J., Wolubah C., and Casaccia-Bonnefil P. Epigenetic memory loss in aging oligodendrocytes in the corpus callosum. Neurobiol. Aging 29 (2008) 452-463
    • (2008) Neurobiol. Aging , vol.29 , pp. 452-463
    • Shen, S.1    Liu, A.2    Li, J.3    Wolubah, C.4    Casaccia-Bonnefil, P.5
  • 157
    • 50249167673 scopus 로고    scopus 로고
    • Age-dependent epigenetic control of differentiation inhibitors is critical for remyelination efficiency
    • Shen S., Sandoval J., Swiss V.A., Li J., Dupree J., Franklin R.J., and Casaccia-Bonnefil P. Age-dependent epigenetic control of differentiation inhibitors is critical for remyelination efficiency. Nat Neurosci. 11 (2008) 1024-1034
    • (2008) Nat Neurosci. , vol.11 , pp. 1024-1034
    • Shen, S.1    Sandoval, J.2    Swiss, V.A.3    Li, J.4    Dupree, J.5    Franklin, R.J.6    Casaccia-Bonnefil, P.7
  • 158
    • 33749383260 scopus 로고    scopus 로고
    • Interferon beta1a reduces plasma CD31+ endothelial microparticles (CD31+EMP) in multiple sclerosis
    • Sheremata W.A., Jy W., Delgado S., Minagar A., McLarty J., and Ahn Y. Interferon beta1a reduces plasma CD31+ endothelial microparticles (CD31+EMP) in multiple sclerosis. J. Neuroinflamm. 3 (2006) 23
    • (2006) J. Neuroinflamm. , vol.3 , pp. 23
    • Sheremata, W.A.1    Jy, W.2    Delgado, S.3    Minagar, A.4    McLarty, J.5    Ahn, Y.6
  • 159
    • 0344824404 scopus 로고    scopus 로고
    • Histone sumoylation is associated with transcriptional repression
    • Shiio Y., and Eisenman R.N. Histone sumoylation is associated with transcriptional repression. Proc. Natl. Acad. Sci. U. S. A. 100 (2003) 13225-13230
    • (2003) Proc. Natl. Acad. Sci. U. S. A. , vol.100 , pp. 13225-13230
    • Shiio, Y.1    Eisenman, R.N.2
  • 160
    • 0037441885 scopus 로고    scopus 로고
    • Histone deacetylase inhibitors: a new class of immunosuppressors targeting a novel signal pathway essential for CD154 expression
    • Skov S., Rieneck K., Bovin L.F., Skak K., Tomra S., Michelsen B.K., and Odum N. Histone deacetylase inhibitors: a new class of immunosuppressors targeting a novel signal pathway essential for CD154 expression. Blood 101 (2003) 1430-1438
    • (2003) Blood , vol.101 , pp. 1430-1438
    • Skov, S.1    Rieneck, K.2    Bovin, L.F.3    Skak, K.4    Tomra, S.5    Michelsen, B.K.6    Odum, N.7
  • 161
    • 17644396349 scopus 로고    scopus 로고
    • Immunology of multiple sclerosis
    • Sospedra M., and Martin R. Immunology of multiple sclerosis. Ann. Rev. Immunol. 23 (2005) 683-747
    • (2005) Ann. Rev. Immunol. , vol.23 , pp. 683-747
    • Sospedra, M.1    Martin, R.2
  • 162
    • 0032702598 scopus 로고    scopus 로고
    • Role of covalent modifications of histones in regulating gene expression
    • Spencer V.A., and Davie J.R. Role of covalent modifications of histones in regulating gene expression. Gene 240 (1999) 1-12
    • (1999) Gene , vol.240 , pp. 1-12
    • Spencer, V.A.1    Davie, J.R.2
  • 163
    • 34250201427 scopus 로고    scopus 로고
    • Lysine-specific demethylase 1 as a potential therapeutic target
    • Stavropoulos P., and Hoelz A. Lysine-specific demethylase 1 as a potential therapeutic target. Exp. Opin. Ther. Targets 11 (2007) 809-820
    • (2007) Exp. Opin. Ther. Targets , vol.11 , pp. 809-820
    • Stavropoulos, P.1    Hoelz, A.2
  • 164
    • 0034610814 scopus 로고    scopus 로고
    • The language of covalent histone modifications
    • Strahl B.D., and Allis C.D. The language of covalent histone modifications. Nature 403 (2000) 41-45
    • (2000) Nature , vol.403 , pp. 41-45
    • Strahl, B.D.1    Allis, C.D.2
  • 166
    • 0028597893 scopus 로고
    • Binding site revealed of nature's most beautiful cofactor
    • Stubbe J. Binding site revealed of nature's most beautiful cofactor. Science (New York, NY) 266 (1994) 1663-1664
    • (1994) Science (New York, NY) , vol.266 , pp. 1663-1664
    • Stubbe, J.1
  • 167
    • 38149020508 scopus 로고    scopus 로고
    • Epigenetic regulation of established human type 1 versus type 2 cytokine responses
    • e53
    • Su R.C., Becker A.B., Kozyrskyj A.L., and Hayglass K.T. Epigenetic regulation of established human type 1 versus type 2 cytokine responses. J. Allergy Clin. Immunol. 121 (2008) 57-63 e53
    • (2008) J. Allergy Clin. Immunol. , vol.121 , pp. 57-63
    • Su, R.C.1    Becker, A.B.2    Kozyrskyj, A.L.3    Hayglass, K.T.4
  • 168
    • 0141884374 scopus 로고    scopus 로고
    • Regulation of microglial inflammatory response by histone deacetylase inhibitors
    • Suuronen T., Huuskonen J., Pihlaja R., Kyrylenko S., and Salminen A. Regulation of microglial inflammatory response by histone deacetylase inhibitors. J. Neurochem. 87 (2003) 407-416
    • (2003) J. Neurochem. , vol.87 , pp. 407-416
    • Suuronen, T.1    Huuskonen, J.2    Pihlaja, R.3    Kyrylenko, S.4    Salminen, A.5
  • 169
    • 0028223453 scopus 로고
    • DNA methylation properties: consequences for pharmacology
    • Szyf M. DNA methylation properties: consequences for pharmacology. Trends Pharmacol. Sci. 15 (1994) 233-238
    • (1994) Trends Pharmacol. Sci. , vol.15 , pp. 233-238
    • Szyf, M.1
  • 171
    • 33751054292 scopus 로고    scopus 로고
    • Eukaryotic DNA replication in a chromatin context
    • Tabancay Jr. A.P., and Forsburg S.L. Eukaryotic DNA replication in a chromatin context. Curr. Top. Dev. Biol. 76 (2006) 129-184
    • (2006) Curr. Top. Dev. Biol. , vol.76 , pp. 129-184
    • Tabancay Jr., A.P.1    Forsburg, S.L.2
  • 172
    • 33748291758 scopus 로고    scopus 로고
    • Roles of jumonji and jumonji family genes in chromatin regulation and development
    • Takeuchi T., Watanabe Y., Takano-Shimizu T., and Kondo S. Roles of jumonji and jumonji family genes in chromatin regulation and development. Dev. Dynam. 235 (2006) 2449-2459
    • (2006) Dev. Dynam. , vol.235 , pp. 2449-2459
    • Takeuchi, T.1    Watanabe, Y.2    Takano-Shimizu, T.3    Kondo, S.4
  • 174
    • 33751001725 scopus 로고    scopus 로고
    • Histone citrullination by protein arginine deiminase: is arginine methylation a green light or a roadblock?
    • Thompson P.R., and Fast W. Histone citrullination by protein arginine deiminase: is arginine methylation a green light or a roadblock?. ACS Chem. Biol. 1 (2006) 433-441
    • (2006) ACS Chem. Biol. , vol.1 , pp. 433-441
    • Thompson, P.R.1    Fast, W.2
  • 175
    • 33646592531 scopus 로고    scopus 로고
    • Sex hormones: a role in the control of multiple sclerosis?
    • Tomassini V., and Pozzilli C. Sex hormones: a role in the control of multiple sclerosis?. Exp. Opin. Pharmacother. 7 (2006) 857-868
    • (2006) Exp. Opin. Pharmacother. , vol.7 , pp. 857-868
    • Tomassini, V.1    Pozzilli, C.2
  • 177
    • 0033845902 scopus 로고    scopus 로고
    • Enhanced T cell responsiveness to citrulline-containing myelin basic protein in Multiple Sclerosis
    • Tranquill L.R., Cao L., Ling N.C., Kalbacher H., Martin R.M., and Whitaker J.N. Enhanced T cell responsiveness to citrulline-containing myelin basic protein in Multiple Sclerosis. Mult. Scler. 6 (2000) 220-225
    • (2000) Mult. Scler. , vol.6 , pp. 220-225
    • Tranquill, L.R.1    Cao, L.2    Ling, N.C.3    Kalbacher, H.4    Martin, R.M.5    Whitaker, J.N.6
  • 178
    • 0033848849 scopus 로고    scopus 로고
    • Histone acetylation and an epigenetic code
    • Turner B.M. Histone acetylation and an epigenetic code. Bioessays 22 (2000) 836-845
    • (2000) Bioessays , vol.22 , pp. 836-845
    • Turner, B.M.1
  • 179
    • 34247531858 scopus 로고    scopus 로고
    • The ambivalent nature of T cell infiltration in the central nervous system of patients with multiple sclerosis
    • Vanderlocht J., Hellings N., Hendriks J.J., and Stinissen P. The ambivalent nature of T cell infiltration in the central nervous system of patients with multiple sclerosis. Crit. Rev. Immunol. 27 (2007) 1-13
    • (2007) Crit. Rev. Immunol. , vol.27 , pp. 1-13
    • Vanderlocht, J.1    Hellings, N.2    Hendriks, J.J.3    Stinissen, P.4
  • 180
    • 0242720407 scopus 로고    scopus 로고
    • PAD, a growing family of citrullinating enzymes: genes, features and involvement in disease
    • Vossenaar E.R., Zendman A.J., van Venrooij W.J., and Pruijn G.J. PAD, a growing family of citrullinating enzymes: genes, features and involvement in disease. Bioessays 25 (2003) 1106-1118
    • (2003) Bioessays , vol.25 , pp. 1106-1118
    • Vossenaar, E.R.1    Zendman, A.J.2    van Venrooij, W.J.3    Pruijn, G.J.4
  • 181
    • 33644629885 scopus 로고    scopus 로고
    • Pregnancy and multiple sclerosis: the children of PRIMS
    • Vukusic S., and Confavreux C. Pregnancy and multiple sclerosis: the children of PRIMS. Clin. Neurol. Neurosurg. 108 (2006) 266-270
    • (2006) Clin. Neurol. Neurosurg. , vol.108 , pp. 266-270
    • Vukusic, S.1    Confavreux, C.2
  • 182
    • 0035063182 scopus 로고    scopus 로고
    • Transcriptional control at regulatory checkpoints by histone deacetylases: molecular connections between cancer and chromatin
    • Wade P.A. Transcriptional control at regulatory checkpoints by histone deacetylases: molecular connections between cancer and chromatin. Hum. Mol. Genet. 10 (2001) 693-698
    • (2001) Hum. Mol. Genet. , vol.10 , pp. 693-698
    • Wade, P.A.1
  • 184
    • 33749371515 scopus 로고    scopus 로고
    • An oligodendrocyte-specific zinc-finger transcription regulator cooperates with Olig2 to promote oligodendrocyte differentiation
    • Wang S.Z., Dulin J., Wu H., Hurlock E., Lee S.E., Jansson K., and Lu Q.R. An oligodendrocyte-specific zinc-finger transcription regulator cooperates with Olig2 to promote oligodendrocyte differentiation. Development (Cambridge, England) 133 (2006) 3389-3398
    • (2006) Development (Cambridge, England) , vol.133 , pp. 3389-3398
    • Wang, S.Z.1    Dulin, J.2    Wu, H.3    Hurlock, E.4    Lee, S.E.5    Jansson, K.6    Lu, Q.R.7
  • 187
    • 33644763991 scopus 로고    scopus 로고
    • Maternal care effects on the hippocampal transcriptome and anxiety-mediated behaviors in the offspring that are reversible in adulthood
    • Weaver I.C., Meaney M.J., and Szyf M. Maternal care effects on the hippocampal transcriptome and anxiety-mediated behaviors in the offspring that are reversible in adulthood. Proc. Natl. Acad. Sci. U. S. A. 103 (2006) 3480-3485
    • (2006) Proc. Natl. Acad. Sci. U. S. A. , vol.103 , pp. 3480-3485
    • Weaver, I.C.1    Meaney, M.J.2    Szyf, M.3
  • 189
    • 34547692686 scopus 로고    scopus 로고
    • Targeting the JMJD2A histone lysine demethylase
    • Wilson J.R. Targeting the JMJD2A histone lysine demethylase. Nat. Struct. Mol. Biol. 14 (2007) 682-684
    • (2007) Nat. Struct. Mol. Biol. , vol.14 , pp. 682-684
    • Wilson, J.R.1
  • 190
    • 0030776198 scopus 로고    scopus 로고
    • Growth characteristics of ganglion cell axons in the developing and regenerating retino-tectal projection of the rat
    • Wizenmann A., and Bahr M. Growth characteristics of ganglion cell axons in the developing and regenerating retino-tectal projection of the rat. Cell Tissue Res. 290 (1997) 395-403
    • (1997) Cell Tissue Res. , vol.290 , pp. 395-403
    • Wizenmann, A.1    Bahr, M.2
  • 191
    • 0033962548 scopus 로고    scopus 로고
    • Oligodendrocyte survival. loss and birth in lesions of chronic-stage multiple sclerosis
    • Wolswijk G. Oligodendrocyte survival. loss and birth in lesions of chronic-stage multiple sclerosis. Brain 123 (2000) 105-115
    • (2000) Brain , vol.123 , pp. 105-115
    • Wolswijk, G.1
  • 192
    • 0029927069 scopus 로고    scopus 로고
    • Acute multiple sclerosis (Marburg type) is associated with developmentally immature myelin basic protein
    • Wood D.D., Bilbao J.M., O'Connors P., and Moscarello M.A. Acute multiple sclerosis (Marburg type) is associated with developmentally immature myelin basic protein. Ann. Neurol. 40 (1996) 18-24
    • (1996) Ann. Neurol. , vol.40 , pp. 18-24
    • Wood, D.D.1    Bilbao, J.M.2    O'Connors, P.3    Moscarello, M.A.4
  • 193
    • 0024567052 scopus 로고
    • The isolation, characterization, and lipid-aggregating properties of a citrulline containing myelin basic protein
    • Wood D.D., and Moscarello M.A. The isolation, characterization, and lipid-aggregating properties of a citrulline containing myelin basic protein. J. Biol. Chem. 264 (1989) 5121-5127
    • (1989) J. Biol. Chem. , vol.264 , pp. 5121-5127
    • Wood, D.D.1    Moscarello, M.A.2
  • 194
    • 32844468049 scopus 로고    scopus 로고
    • Histone arginine methylation and its dynamic regulation
    • Wysocka J., Allis C.D., and Coonrod S. Histone arginine methylation and its dynamic regulation. Front. Biosci. 11 (2006) 344-355
    • (2006) Front. Biosci. , vol.11 , pp. 344-355
    • Wysocka, J.1    Allis, C.D.2    Coonrod, S.3
  • 195
    • 24144470824 scopus 로고    scopus 로고
    • Taking LSD 1 to a new high
    • Wysocka J., Milne T.A., and Allis C.D. Taking LSD 1 to a new high. Cell 122 (2005) 654-658
    • (2005) Cell , vol.122 , pp. 654-658
    • Wysocka, J.1    Milne, T.A.2    Allis, C.D.3
  • 196
    • 33847042352 scopus 로고    scopus 로고
    • Evidence that tumor necrosis factor related apoptosis-inducing ligand induction by 5-Aza-2'-deoxycytidine sensitizes human breast cancer cells to adriamycin
    • Xu J., Zhou J.Y., Tainsky M.A., and Wu G.S. Evidence that tumor necrosis factor related apoptosis-inducing ligand induction by 5-Aza-2'-deoxycytidine sensitizes human breast cancer cells to adriamycin. Cancer Res. 67 (2007) 1203-1211
    • (2007) Cancer Res. , vol.67 , pp. 1203-1211
    • Xu, J.1    Zhou, J.Y.2    Tainsky, M.A.3    Wu, G.S.4
  • 197
    • 2342599619 scopus 로고    scopus 로고
    • The diverse superfamily of lysine acetyltransferases and their roles in leukemia and other diseases
    • Yang X.J. The diverse superfamily of lysine acetyltransferases and their roles in leukemia and other diseases. Nucleic Acids Res. 32 (2004) 959-976
    • (2004) Nucleic Acids Res. , vol.32 , pp. 959-976
    • Yang, X.J.1
  • 198
    • 0141885037 scopus 로고    scopus 로고
    • From discovery to the coming generation of histone deacetylase inhibitors
    • Yoshida M., Matsuyama A., Komatsu Y., and Nishino N. From discovery to the coming generation of histone deacetylase inhibitors. Curr. Med. Chem. 10 (2003) 2351-2358
    • (2003) Curr. Med. Chem. , vol.10 , pp. 2351-2358
    • Yoshida, M.1    Matsuyama, A.2    Komatsu, Y.3    Nishino, N.4
  • 199
    • 33845947272 scopus 로고    scopus 로고
    • Relationship between the clinical scoring and demyelination in central nervous system with total antioxidant capacity of plasma during experimental autoimmune encephalomyelitis development in mice
    • Zargari M., Allameh A., Sanati M.H., Tiraihi T., Lavasani S., and Emadyan O. Relationship between the clinical scoring and demyelination in central nervous system with total antioxidant capacity of plasma during experimental autoimmune encephalomyelitis development in mice. Neurosci. Lett. 412 (2007) 24-28
    • (2007) Neurosci. Lett. , vol.412 , pp. 24-28
    • Zargari, M.1    Allameh, A.2    Sanati, M.H.3    Tiraihi, T.4    Lavasani, S.5    Emadyan, O.6
  • 200
    • 0035883954 scopus 로고    scopus 로고
    • Transcription regulation by histone methylation: interplay between different covalent modifications of the core histone tails
    • Zhang Y., and Reinberg D. Transcription regulation by histone methylation: interplay between different covalent modifications of the core histone tails. Genes Dev. 15 (2001) 2343-2360
    • (2001) Genes Dev. , vol.15 , pp. 2343-2360
    • Zhang, Y.1    Reinberg, D.2
  • 201
    • 0028874611 scopus 로고
    • The effects of citrullination on variable aminoterminus acylation on the encephalitogenicity of human MBP in the Pl?J mouse
    • Zhou S.R., Moscarello M.A., and Whitaker J.N. The effects of citrullination on variable aminoterminus acylation on the encephalitogenicity of human MBP in the Pl?J mouse. J. Neuroimmunol. 62 (1995) 147-152
    • (1995) J. Neuroimmunol. , vol.62 , pp. 147-152
    • Zhou, S.R.1    Moscarello, M.A.2    Whitaker, J.N.3
  • 202
    • 34248680532 scopus 로고    scopus 로고
    • HLA-DRB1*1501, -DQB1*0301, -DQB1*0302, -DQB1*0602, and -DQB1*0603 alleles are associated with more severe disease outcome on MRI in patients with multiple sclerosis
    • Zivadinov R., Uxa L., Bratina A., Bosco A., Srinivasaraghavan B., Minagar A., Ukmar M., Benedetto S., and Zorzon M. HLA-DRB1*1501, -DQB1*0301, -DQB1*0302, -DQB1*0602, and -DQB1*0603 alleles are associated with more severe disease outcome on MRI in patients with multiple sclerosis. Int. Rev. Neurobiol. 79 (2007) 521-535
    • (2007) Int. Rev. Neurobiol. , vol.79 , pp. 521-535
    • Zivadinov, R.1    Uxa, L.2    Bratina, A.3    Bosco, A.4    Srinivasaraghavan, B.5    Minagar, A.6    Ukmar, M.7    Benedetto, S.8    Zorzon, M.9


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